SCGB1C1 Gene
protein-coding GIFtS: 40
GCID: GC11P000187
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secretoglobin, family 1C, member 1
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Aliases
for SCGB1C1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Secretoglobin, Family 1C, Member 11 2 | | RYD51 2 | | Secretoglobin RYD52 3 | | Ligand Binding Protein RYD52 | | Secretoglobin Family 1C Member 12 |
Export aliases for SCGB1C1 gene to outside databasesPrevious GC identifer: GC11P000012 |
Summaries
for SCGB1C1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for SCGB1C1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_009237.18
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for SCGB1C1
Other transcription factors
Search SABiosciences Chromatin IP Primers for SCGB1C1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SCGB1C1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11p15.5 Ensembl cytogenetic band: 11p15.5 HGNC cytogenetic band: 11p15.5SCGB1C1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11P000187: view genomic region
(about GC identifiers)
Start:
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193,080 bp from pter |
End:
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194,573 bp from pter |
Size:
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1,494 bases |
Orientation:
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plus strand |
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Proteins
for SCGB1C1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SG1C1_HUMAN, Q8TD33 (See
protein sequence)Recommended Name: Secretoglobin family 1C member 1 precursor Size: 95 amino acids; 10414 Da
Subcellular location: Secreted (By similarity)
Secondary accessions: A8MSI9 Q14DW0Explore the universe of human proteins at neXtProt for SCGB1C1: NX_Q8TD33
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8TD33
SCGB1C1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_663626.2
ENSEMBL proteins: ENSP00000344545
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005576 | extracellular region |
IEA | -- |
SCGB1C1 for ontologies About GeneDecksing
SCGB1C1 Antibody Products:
Assay Products for SCGB1C1: |
Protein
Domains /
Families
for SCGB1C1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SCGB1C1 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8TD33ProtoNet protein and cluster: Q8TD33 1 Blocks protein family: IPB003628 Uteroglobin subtype
UniProtKB/Swiss-Prot: SG1C1_HUMAN, Q8TD33Similarity: Belongs to the secretoglobin family |
Function
for SCGB1C1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SCGB1C1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SCGB1C1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SCGB1C1 (NM_145651) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SCGB1C1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCGB1C1 |
|
Pathways & Interactions
for SCGB1C1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SCGB1C1
|
Drugs & Compounds
for SCGB1C1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SCGB1C1
Search CenterWatch for drugs/clinical trials and news about SCGB1C1 / SG1C1
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Transcripts
for SCGB1C1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SCGB1C1 gene: NM_145651.2 Unigene Cluster for SCGB1C1: Secretoglobin, family 1C, member 1 Hs.127059 [show with all ESTs]Unigene Representative Sequence: EL7363761 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000342878(uc001loa.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SCGB1C1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SCGB1C1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SCGB1C1 (NM_145651) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SCGB1C1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCGB1C1 |
Additional cDNA sequence: AY026938.1 BC069287.1 BC111427.1 BC111433.1 1 DOTS entry: DT.40126780 7 AceView cDNA sequences: BX098294 AY026938 AI791374 NM_145651 BC069287 BK000201 AI732981
GeneLoc Exon Structure
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Expression
for SCGB1C1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SCGB1C1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAAATGTATC
About this image
See SCGB1C1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SCGB1C1
SOURCE GeneReport for Unigene cluster: Hs.127059
SABiosciences Custom PCR Arrays for SCGB1C1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SCGB1C1
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat SCGB1C1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SCGB1C1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SCGB1C1 |
Orthologs
for SCGB1C1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of chordates.
Orthologs for SCGB1C1 gene from 2/7 species (see all 7) About this table
ENSEMBL Gene Tree for SCGB1C1 (if available)
TreeFam Gene Tree for SCGB1C1 (if available) |
Paralogs
for SCGB1C1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for SCGB1C1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SCGB1C1 (193080 - 194573 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for SCGB1C1
1 CNV: 71209
1 Indel: 101100 | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for SCGB1C1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SCGB1C1 for disorders About GeneDecksing
OMIM gene information: 610176
OMIM disorders: --
1  disease for SCGB1C1: About MalaCardscommon cold
1 disease from the University of Copenhagen DISEASES database for SCGB1C1:Common cold Export disorders for SCGB1C1 gene to outside databases
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Publications
for SCGB1C1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SCGB1C1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with SCGB1C1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Update of the human secretoglobin (SCGB) gene superfa mily and an example of 'evolutionary bloom' of androgen-binding protein genes w ithin the mouse Scgb gene superfamily. (PubMed id 22155607)1, 3 Jackson B.C....Vasiliou V. (2011)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in mouse and human airways. (PubMed id 12406855)1, 2 Reynolds S.D.... Stripp B.R. (2002)
- The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (2006)
- Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (2006)
- From ORFeome to biology: a functional genomics pipeline. (PubMed id 15489336)1 Wiemann S....Poustka A. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
- DNA cloning using in vitro site-specific recombination. (PubMed id 11076863)1 Hartley J.L....Brasch M.A. (2000)
- Novel genes for potential ligand-binding proteins in subregions of the olfactory mucosa. (PubMed id 1915264)1 Dear T.N....Rabbitts T.H. (1991)
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External Searches for SCGB1C1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing SCGB1C1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing SCGB1C1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SCGB1C1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SCGB1C1 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for SCGB1C1 gene:
Search GeneIP for patents involving SCGB1C1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SCGB1C1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SCGB1C1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SCGB1C1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SCGB1C1 | | | OriGene Protein Over-expression Lysate for SCGB1C1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SCGB1C1 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SCGB1C1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SCGB1C1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for SCGB1C1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SCGB1C1 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SCGB1C1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SCGB1C1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SCGB1C1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SCGB1C1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SCGB1C1 |
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| | | | Search Tocris compounds for SCGB1C1 |
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 | | | SCGB1C1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for SCGB1C1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCGB1C1 |
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