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SCG3 Gene

protein-coding   GIFtS: 56
GCID: GC15P051973

Secretogranin III

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Secretogranin III1 2 3
SGIII2
secretogranin-32
SgIII3

External Ids:    HGNC: 137071   Entrez Gene: 291062   Ensembl: ENSG000001041127   OMIM: 6117965   UniProtKB: Q8WXD23   

Export aliases for SCG3 gene to outside databases

Previous GC identifers: GC15P047530 GC15P045020 GC15P049552 GC15P049689 GC15P049760 GC15P028804


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SCG3 Gene:
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory
proteins. Granins may serve as precursors for biologically active peptides. Some granins have been shown to
function as helper proteins in sorting and proteolytic processing of prohormones; however, the function of this
protein is unknown. Two transcript variants encoding different isoforms have been found for this gene. (provided
by RefSeq, Sep 2009)

GeneCards Summary for SCG3 Gene:
SCG3 (secretogranin III) is a protein-coding gene. Diseases associated with SCG3 include limb-girdle muscular dystrophy, type 2c, and limb-girdle muscular dystrophy.

Gene Wiki entry for SCG3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000015.10  NC_018926.2  NT_010194.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the SCG3 gene promoter:
         STAT5B   AML1a   POU3F1   NRSF form 1   IRF-1   NRSF form 2   FAC1   SRY   FOXJ2 (long isoform)   FOXJ2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSCG3 promoter sequence
   Search Chromatin IP Primers for SCG3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SCG3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q21   Ensembl cytogenetic band:  15q21.2   HGNC cytogenetic band: 15q21.2

SCG3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SCG3 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P051973:  view genomic region     (about GC identifiers)

Start:
51,973,550 bp from pter      End:
52,013,223 bp from pter
Size:
39,674 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: SCG3_HUMAN, Q8WXD2 (See protein sequence)
Recommended Name: Secretogranin-3 precursor  
Size: 468 amino acids; 53005 Da
Subunit: Interacts with CHGA (By similarity)
Secondary accessions: A8K2B0 B3KQP6 B4DK99 F5H3R8 Q96C83 Q96GE8 Q9Y6G7
Alternative splicing: 2 isoforms:  Q8WXD2-1   Q8WXD2-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SCG3: NX_Q8WXD2

Explore proteomics data for SCG3 at MOPED

Post-translational modifications: 

  • O-glycosylated1
  • Glycosylation2 at Asn68, Thr144, Thr216, Thr231, Asn346, Ser359
  • Modification sites at PhosphoSitePlus

  • See SCG3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001158729.1  NP_037375.2  

    ENSEMBL proteins: 
     ENSP00000220478   ENSP00000445205   ENSP00000452745  
    Reactome Protein details: Q8WXD2

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR026197 SCG3

    Graphical View of Domain Structure for InterPro Entry Q8WXD2

    ProtoNet protein and cluster: Q8WXD2


    SCG3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0044822poly(A) RNA binding IDA--
         
    SCG3 for ontologies           About GeneDecksing


    Animal Models:
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SCG3
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    miRNA
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    miRTarBase miRNAs that target SCG3:
    hsa-mir-335-5p (MIRT017386)

    Block miRNA regulation of human, mouse, rat SCG3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SCG3 (see all 9):
    hsa-miR-3163 hsa-miR-4291 hsa-miR-576-5p hsa-miR-4307 hsa-miR-4263 hsa-miR-606 hsa-miR-3920 hsa-miR-330-3p
    SwitchGear 3'UTR luciferase reporter plasmidSCG3 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for SCG3
    Predesigned siRNA for gene silencing in human, mouse, rat SCG3

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector (see all 2): SCG3 (NM_013243)
    Sino Biological Human cDNA Clone for SCG3
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SCG3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCG3

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCG3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SCG3_HUMAN, Q8WXD2: Cytoplasmic vesicle, secretory vesicle lumen (By similarity). Cytoplasmic vesicle, secretory
    vesicle membrane; Peripheral membrane protein (By similarity). Secreted. Note=Associated with the secretory
    granule membrane through direct binding to cholesterol-enriched lipid rafts in intragranular conditions (By
    similarity). Neuroendocrine and endocrine secretory granules
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    endoplasmic reticulum2
    cytosol1
    mitochondrion1
    nucleus1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--
    GO:0030658transport vesicle membrane IEA--
    GO:0034774secretory granule lumen TAS--

    SCG3 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SCG3 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Response to elevated platelet cytosolic Ca2+
    Response to elevated platelet cytosolic Ca2+0.94
    Platelet degranulation0.94
    2Hemostasis
    Hemostasis0.43
    Platelet activation, signaling and aggregation0.43

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Reactome Pathway for SCG3
        Platelet degranulation



    SCG3 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SCG3
    Interactions:

        GeneGlobe Interaction Network for SCG3

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for SCG3 (Q8WXD23 ENSP000002204784) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CHGAP106453, ENSP000002164924I2D: score=1 STRING: ENSP00000216492
    PTK2Q053973I2D: score=1 
    FLNCENSP000003271454STRING: ENSP00000327145
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002576platelet degranulation TAS--
    GO:0007596blood coagulation TAS--
    GO:0030168platelet activation TAS--

    SCG3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SCG3

    1 Novoseek inferred chemical compound relationship for SCG3 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    testosterone 21.1 1 10027412 (1)



    SCG3 for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SCG3 gene (2 alternative transcripts): 
    NM_001165257.1  NM_013243.3  

    Unigene Cluster for SCG3:

    Secretogranin III
    Hs.232618  [show with all ESTs]
    Unigene Representative Sequence: AF453583
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000220478(uc002abh.3 uc010ufz.2) ENST00000542355 ENST00000558709

    miRNA
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    Block miRNA regulation of human, mouse, rat SCG3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SCG3 (see all 9):
    hsa-miR-3163 hsa-miR-4291 hsa-miR-576-5p hsa-miR-4307 hsa-miR-4263 hsa-miR-606 hsa-miR-3920 hsa-miR-330-3p
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    OriGene qPCR primer pairs and template standards for SCG3
    OriGene qSTAR qPCR primer pairs in human, mouse for SCG3
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      QuantiTect SYBR Green Assays in human, mouse, rat SCG3
      QuantiFast Probe-based Assays in human, mouse, rat SCG3

    Additional mRNA sequence: 

    AF078851.1 AF453583.1 AK075314.1 AK290175.1 AK296466.1 AY359093.1 BC009511.2 BC014539.1 

    7 DOTS entries:

    DT.113058  DT.95374661  DT.92432117  DT.100787799  DT.97845265  DT.92432116  DT.121075796 

    Selected AceView cDNA sequences (see all 169):

    AK075314 AW444753 AA364934 AA127581 CA976030 AL713343 BU176773 BQ128196 
    AA234547 AY359093 BI823378 BM452526 BX488794 AI423166 BQ130506 BQ638034 
    F11631 BX094948 CR597634 BQ637862 AI990706 BQ288004 CR609040 AI589601 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for SCG3    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12
    SP1:                                                                              
    SP2:                          -                                                   


    ECgene alternative splicing isoforms for SCG3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SCG3 expression in normal human tissues (normalized intensities)      SCG3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGAGGGGACA
    SCG3 Expression
    About this image


    SCG3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 11) fully expand
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 6 entries
             hIPS1
     
     Pancreas (Endocrine System)    fully expand to see all 5 entries
             Endocrine Progenitor Cells Ventral Pancreatic Bud
             Islets of Langerhans
     
     Brain (Nervous System)    fully expand to see all 5 entries
             Cerebellum
             Oligodendrocyte-like cells
     
     Neural Tube (Nervous System)    fully expand to see all 3 entries
             Metencephalon
     
     Eye (Sensory Organs)    fully expand to see all 3 entries
             Mature Horizontal Cells Inner Nuclear Layer
    SCG3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SCG3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.232618

    UniProtKB/Swiss-Prot: SCG3_HUMAN, Q8WXD2
    Tissue specificity: Expressed in brain, heart, kidney, liver and skeletal muscle

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for SCG3 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Scg31 , 5 secretogranin III1, 5 86.25(n)1
    88.89(a)1
      9 (42.32 cM)5
    202551  NM_009130.31  NP_033156.11 
     756433665 
    chicken
    (Gallus gallus)
    Aves SCG31 secretogranin III 73.22(n)
    68.87(a)
      415424  XM_413807.4  XP_413807.2 
    lizard
    (Anolis carolinensis)
    Reptilia SCG36
    secretogranin III
    63(a)
    1 ↔ 1
    GL343330.1(682510-720932)
    African clawed frog
    (Xenopus laevis)
    Amphibia scg3-A2 secretogranin III 76.18(n)    X92872.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc732362 hypothetical protein MGC73236 74.93(n)   393730  BC059577.1 


    ENSEMBL Gene Tree for SCG3 (if available)
    TreeFam Gene Tree for SCG3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Polymorphic Variants from UniProtKB/Swiss-Prot
    SCG3_HUMAN, Q8WXD2: Polymorphisms in the 5'-flanking region and in intron 1 may have an effect on transcriptional
    activity and be associated with an increase in subcutaneous, but not visceral, fat area. Hence, may influence the
    risk of obesity


    Selected SNPs for SCG3 (see all 954)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs774767361,2
    C,F--28831823(+) GGAGGC/TCTCAG 2 -- int12Minor allele frequency- T:0.50NA 4
    rs1830265261,2
    --32038401(+) CCTGTA/TAAGTG 2 -- us2k10--------
    rs1856966091,2
    --32038406(+) TAAGTG/TAATTG 2 -- us2k10--------
    rs1475605761,2
    --32038488(+) TGAATA/GATGTA 2 -- us2k10--------
    rs1922931141,2
    --32038503(+) AATTCA/GTGCCT 2 -- us2k10--------
    rs10176781,2
    C,F,O,A,H--32038555(-) GGATCA/GTGTTA 2 -- us2k128Minor allele frequency- G:0.31NS EA NA 6992
    rs800773901,2
    C,F--32038589(+) AATCAC/TTTTAA 2 -- us2k11Minor allele frequency- T:0.02NA 120
    rs1181659151,2
    F--32038658(+) ACTCAA/GCAGAC 2 -- us2k11Minor allele frequency- G:0.01NA 120
    rs1419958221,2
    --32038661(+) CAACAA/GACATC 2 -- us2k10--------
    rs37642201,2
    C,F,H--32038689(+) CCTGAA/GTCTCT 2 -- us2k124Minor allele frequency- G:0.12EA NA NS CSA WA 6870

    HapMap Linkage Disequilibrium report for SCG3 (51973550 - 52013223 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for SCG3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv270503CNV Insertion20981092
    nsv457139CNV Loss19166990
    nsv904219CNV Loss21882294
    nsv471243CNV Gain18288195

    Human Gene Mutation Database (HGMD): SCG3
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SCG3
    DNA2.0 Custom Variant and Variant Library Synthesis for SCG3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611796    OMIM disorders: --

    15 diseases for SCG3:    About MalaCards
    limb-girdle muscular dystrophy, type 2c    limb-girdle muscular dystrophy    neuroendocrine tumor    pituitary adenoma
    muscular dystrophy    major depressive disorder    adenoma    obesity
    asthma    tonsillitis    prostate cancer    prostatitis
    cerebritis    pancreatitis    neuronitis


    SCG3 for disorders           About GeneDecksing

    2 Novoseek inferred disease relationships for SCG3 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    adenoma 20 3 7680355 (1), 8162254 (1)
    tumors 0 2 7680355 (1), 8162254 (1)

    Genetic Association Database (GAD): SCG3
    Human Genome Epidemiology (HuGE) Navigator: SCG3 (5 documents)

    Export disorders for SCG3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SCG3 gene, integrated from 10 sources (see all 46):
    (articles sorted by number of sources associating them with SCG3)
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    1. Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity. (PubMed id 17200173)1, 2, 4, 9 Tanabe A.... Hotta K. (J. Clin. Endocrinol. Metab. 2007)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    4. Cloning and characterization of a novel human secretory protein: secretogranin III. (PubMed id 12098761)1, 2 Rong Y.P.... Han Z.G. (Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao 2002)
    5. The granin family--its role in sorting and secretory granule formation. (PubMed id 8825061)1, 3 Ozawa H. and Takata K. (Cell Struct. Funct. 1995)
    6. The granin (chromogranin/secretogranin) family. (PubMed id 2053134)1, 3 Huttner W.B....Rosa P. (Trends Biochem. Sci. 1991)
    7. LDL oxidation by THP-1 monocytes: implication of HNP-1, SgIII and DMT-1. (PubMed id 19150442)1, 9 He C....Wu J. ( international journal of clinical chemistry 2009)
    8. Measurements of secretogranins II, III, V and proconvertases 1/3 and 2 in plasma from patients with neuroendocrine tumours. (PubMed id 18448176)1, 9 Stridsberg M....Janson E.T. (Regul. Pept. 2008)
    9. Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions. (PubMed id 14630798)1, 9 Coppinger J.A....Maguire P.B. (Blood 2004)
    10. Protein interaction discovery using parallel analysis of translated ORFs (PLATO). (PubMed id 23503679)1 Zhu J....Elledge S.J. (Nat. Biotechnol. 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 29106 HGNC: 13707 AceView: SCG3 Ensembl:ENSG00000104112 euGenes: HUgn29106
    ECgene: SCG3 H-InvDB: SCG3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SCG3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SCG3 gene:
    Search GeneIP for patents involving SCG3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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