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Aliases for SCD Gene

Aliases for SCD Gene

  • Stearoyl-CoA Desaturase 2 3 4 5
  • Fatty Acid Desaturase 2 3 4
  • Stearoyl-CoA Desaturase (Delta-9-Desaturase) 2 3
  • Stearoyl-CoA Desaturase Opposite Strand 2 3
  • Acyl-CoA Desaturase 2 3
  • Delta(9)-Desaturase 3 4
  • EC 1.14.19.1 4 58
  • HSCD1 3 4
  • Predicted Protein Of HQ0998 3
  • Delta-9-Desaturase 2
  • Delta-9 Desaturase 4
  • MSTP008 3
  • FADS5 3
  • SCDOS 3
  • SCD1 3

External Ids for SCD Gene

Previous HGNC Symbols for SCD Gene

  • SCDOS

Previous GeneCards Identifiers for SCD Gene

  • GC10P101000
  • GC10P101340
  • GC10P102238
  • GC10P101771
  • GC10P102096
  • GC10P095735

Summaries for SCD Gene

Entrez Gene Summary for SCD Gene

  • This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. The protein belongs to the fatty acid desaturase family and is an integral membrane protein located in the endoplasmic reticulum. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detected. A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17. [provided by RefSeq, Sep 2015]

GeneCards Summary for SCD Gene

SCD (Stearoyl-CoA Desaturase) is a Protein Coding gene. Diseases associated with SCD include Reye Syndrome and Obesity. Among its related pathways are oleate biosynthesis and Metabolism. GO annotations related to this gene include iron ion binding and stearoyl-CoA 9-desaturase activity. An important paralog of this gene is SCD5.

UniProtKB/Swiss-Prot for SCD Gene

  • Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates (PubMed:15907797, PubMed:18765284). Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (PubMed:15907797, PubMed:18765284). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids (PubMed:15610069). Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation (By similarity). Plays an important role in body energy homeostasis (By similarity). Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity).

Gene Wiki entry for SCD Gene

Additional gene information for SCD Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SCD Gene

Genomics for SCD Gene

Regulatory Elements for SCD Gene

Enhancers for SCD Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10H100369 1.8 FANTOM5 ENCODE dbSUPER 12.9 +25.4 25429 6 MLX FEZF1 DMAP1 YY1 ZNF548 SP3 NFYC MEF2D GLIS1 NBN ENSG00000231188 PHBP9 SEC31B HIF1AN EBAG9P1 SPCS2P2 TPM4P1 LOC101927300 SCD CHUK
GH10H100507 1.3 Ensembl ENCODE dbSUPER 11.3 +162.6 162563 4 CTCF PKNOX1 NFIB MAX RAD21 RFX5 GATA3 POLR2A EGR1 SMC3 SEC31B ENSG00000231188 SCD GC10M100502 GC10M100501
GH10H100433 1 Ensembl 12.2 +86.7 86687 0 HDGF ATF1 ARNT SIN3A SLC30A9 ZNF143 ATF7 SP3 REST MIER2 ENSG00000231188 SCD WNT8B SEC31B HIF1AN NDUFB8 ENSG00000255339 ENSG00000212325
GH10H100434 1 ENCODE 12.2 +86.9 86944 0 HDGF ATF1 ARNT ARID4B SIN3A ZNF2 SLC30A9 ZNF143 ATF7 DEK SEC31B SCD ENSG00000231188 WNT8B HIF1AN NDUFB8 ENSG00000255339 ENSG00000212325
GH10H100307 1 FANTOM5 ENCODE 11.3 -39.1 -39115 0 TBP STAT1 MXI1 JUN MAX USF2 CEBPB RAD21 EP300 RFX5 BLOC1S2 CWF19L1 ENSG00000231188 SCD MRPL43 ERLIN1 DNMBP
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SCD on UCSC Golden Path with GeneCards custom track

Promoters for SCD Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000032502 585 2401 MLX ARID4B SIN3A DMAP1 YY1 FOS SP3 SP5 ZHX2 MXD4

Genomic Location for SCD Gene

Chromosome:
10
Start:
100,347,015 bp from pter
End:
100,364,834 bp from pter
Size:
17,820 bases
Orientation:
Plus strand

Genomic View for SCD Gene

Genes around SCD on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SCD Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SCD Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SCD Gene

Proteins for SCD Gene

  • Protein details for SCD Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O00767-ACOD_HUMAN
    Recommended name:
    Acyl-CoA desaturase
    Protein Accession:
    O00767
    Secondary Accessions:
    • B2R5U0
    • D3DR68
    • Q16150
    • Q53GR9
    • Q5W037
    • Q5W038
    • Q6GSS4
    • Q96KF6
    • Q9BS07
    • Q9Y695

    Protein attributes for SCD Gene

    Size:
    359 amino acids
    Molecular mass:
    41523 Da
    Cofactor:
    Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
    Quaternary structure:
    • May self-associate and form homodimers.

    Three dimensional structures from OCA and Proteopedia for SCD Gene

neXtProt entry for SCD Gene

Selected DME Specific Peptides for SCD Gene

O00767:
  • SHVGWLLV
  • LLHLGALYG
  • FPYDYSASEYRWHIN
  • NTMAFQNDV
  • PTLVPWY
  • LVNSAAH
  • TWLVNSA
  • HRLWSHR
  • RDHRAHH
  • GEGFHNYHH

Post-translational modifications for SCD Gene

  • Ubiquitination at isoforms=162, isoforms=196, Lys209, and Lys341
  • Modification sites at PhosphoSitePlus

Other Protein References for SCD Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

  • Cell Signaling Technology (CST) Antibodies for SCD (SCD)

Domains & Families for SCD Gene

Gene Families for SCD Gene

HGNC:
Human Protein Atlas (HPA):
  • Enzymes
  • Predicted membrane proteins

Protein Domains for SCD Gene

Suggested Antigen Peptide Sequences for SCD Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O00767

UniProtKB/Swiss-Prot:

ACOD_HUMAN :
  • The histidine box domains are involved in binding the catalytic metal ions.
  • Belongs to the fatty acid desaturase type 1 family.
Domain:
  • The histidine box domains are involved in binding the catalytic metal ions.
Family:
  • Belongs to the fatty acid desaturase type 1 family.
genes like me logo Genes that share domains with SCD: view

Function for SCD Gene

Molecular function for SCD Gene

GENATLAS Biochemistry:
stearol-CoA-desaturase
UniProtKB/Swiss-Prot CatalyticActivity:
Stearoyl-CoA + 2 ferrocytochrome b5 + O(2) + 2 H(+) = oleoyl-CoA + 2 ferricytochrome b5 + 2 H(2)O.
UniProtKB/Swiss-Prot Function:
Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates (PubMed:15907797, PubMed:18765284). Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (PubMed:15907797, PubMed:18765284). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids (PubMed:15610069). Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation (By similarity). Plays an important role in body energy homeostasis (By similarity). Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity).

Enzyme Numbers (IUBMB) for SCD Gene

Phenotypes From GWAS Catalog for SCD Gene

Gene Ontology (GO) - Molecular Function for SCD Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004768 stearoyl-CoA 9-desaturase activity TAS --
GO:0005506 iron ion binding IDA 18765284
GO:0016491 oxidoreductase activity IDA,IEA 15907797
GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with SCD: view
genes like me logo Genes that share phenotypes with SCD: view

Animal Models for SCD Gene

MGI Knock Outs for SCD:

Animal Model Products

  • Taconic Biosciences Mouse Models for SCD

CRISPR Products

miRNA for SCD Gene

miRTarBase miRNAs that target SCD

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for SCD
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for SCD Gene

Localization for SCD Gene

Subcellular locations from UniProtKB/Swiss-Prot for SCD Gene

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SCD gene
Compartment Confidence
nucleus 5
endoplasmic reticulum 5
peroxisome 3
cytosol 3
plasma membrane 2
extracellular 2
mitochondrion 2
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Endoplasmic reticulum (4)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for SCD Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IDA --
GO:0005783 endoplasmic reticulum IEA,IDA --
GO:0005789 endoplasmic reticulum membrane TAS --
GO:0016020 membrane IDA,IEA 19946888
GO:0016021 integral component of membrane IDA,IEA 18765284
genes like me logo Genes that share ontologies with SCD: view

Pathways & Interactions for SCD Gene

genes like me logo Genes that share pathways with SCD: view

SIGNOR curated interactions for SCD Gene

Is inactivated by:

Gene Ontology (GO) - Biological Process for SCD Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006629 lipid metabolic process IEA --
GO:0006631 fatty acid metabolic process IEA --
GO:0006633 fatty acid biosynthetic process IEA --
GO:0006636 unsaturated fatty acid biosynthetic process IDA 15907797
GO:0045540 regulation of cholesterol biosynthetic process TAS --
genes like me logo Genes that share ontologies with SCD: view

Drugs & Compounds for SCD Gene

(68) Drugs for SCD Gene - From: ClinicalTrials, ApexBio, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Oxygen Approved, Vet_approved Pharma 0
alemtuzumab Approved, Investigational Pharma Therapeutic Antibodies 316
Bosentan Approved, Investigational Pharma 106
Busulfan Approved, Investigational Pharma 556
Carbon monoxide Approved Pharma 130

(59) Additional Compounds for SCD Gene - From: HMDB and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
acetyl-coa
  • Ac-CoA
  • Ac-Coenzyme A
  • Ac-S-CoA
  • Ac-S-Coenzyme A
  • Acetyl coenzyme-A
72-89-9
stearoyl-coa
  • Octadecanoyl-CoA
  • Octadecanoyl-coenzyme A
  • S-Octadecanoate
  • S-Octadecanoate CoA
  • S-Octadecanoate Coenzyme A
362-66-3
(2E)-Decenoyl-CoA
  • (E)-S-2-decenoate
  • (E)-S-2-decenoate CoA
  • (E)-S-2-decenoate Coenzyme A
  • (E)-S-2-decenoic acid
  • 2-trans-Decenoyl-CoA
10018-95-8
(2E)-Dodecenoyl-CoA
  • (2E)-Dodec-2-enoyl-CoA
  • (2E)-Dodec-2-enoyl-Coenzyme A
  • 2-trans-Dodecenoyl-CoA
  • 2-trans-Dodecenoyl-Coenzyme A
1066-12-2
(2E)-Hexadecenoyl-CoA
  • (2E)-Hexadecenoyl-CoA
  • (2E)-Hexadecenoyl-Coenzyme A
  • trans-2-Hexadecenoyl-CoA
  • trans-2-Hexadecenoyl-Coenzyme A
4460-95-1

(4) ApexBio Compounds for SCD Gene

Compound Action Cas Number
A939572 Stearoyl-CoA desaturase1 (SCD1) inhibitor 1032229-33-6
MK-8245 SCD inhibitor,potent and liver-selective 1030612-90-8
MK-8245 Trifluoroacetate 1415559-41-9
PluriSIn #1 (NSC 14613) SCD1 inhibitor 91396-88-2
genes like me logo Genes that share compounds with SCD: view

Drug Products

Transcripts for SCD Gene

mRNA/cDNA for SCD Gene

(1) REFSEQ mRNAs :
(11) Additional mRNA sequences :
(1725) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SCD Gene

Stearoyl-CoA desaturase (delta-9-desaturase):
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for SCD
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for SCD Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6
SP1: -
SP2:

Relevant External Links for SCD Gene

GeneLoc Exon Structure for
SCD
ECgene alternative splicing isoforms for
SCD

Expression for SCD Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SCD Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SCD Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x7.2), Adipose - Visceral (Omentum) (x6.0), and Adipose - Subcutaneous (x4.9).

Protein differential expression in normal tissues from HIPED for SCD Gene

This gene is overexpressed in Fetal testis (11.1), Bone (10.3), Lung (10.0), Fetal Liver (8.0), Adrenal (7.5), and Spinal cord (6.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for SCD Gene



NURSA nuclear receptor signaling pathways regulating expression of SCD Gene:

SCD

SOURCE GeneReport for Unigene cluster for SCD Gene:

Hs.558396

mRNA Expression by UniProt/SwissProt for SCD Gene:

O00767-ACOD_HUMAN
Tissue specificity: Detected in fetal liver, lung and brain. Highly expressed in adult adipose tissue, and at lower levels in adult brain and lung.

Evidence on tissue expression from TISSUES for SCD Gene

  • Liver(5)
  • Nervous system(5)
  • Skin(4.9)
  • Intestine(4.5)
  • Lung(4.2)
  • Pancreas(4.2)
  • Muscle(4.1)
  • Kidney(3.9)
  • Eye(3.7)
  • Blood(3.1)
  • Heart(2.7)
  • Stomach(2.7)
  • Bone(2.3)
genes like me logo Genes that share expression patterns with SCD: view

No data available for Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for SCD Gene

Orthologs for SCD Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for SCD Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SCD 33 34
  • 99.44 (n)
dog
(Canis familiaris)
Mammalia SCD 33 34
  • 89.42 (n)
cow
(Bos Taurus)
Mammalia SCD 33 34
  • 86.07 (n)
-- 34
  • 84 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Scd1 33
  • 83.61 (n)
mouse
(Mus musculus)
Mammalia Scd2 34
  • 83 (a)
OneToMany
Scd3 34
  • 83 (a)
OneToMany
Scd1 33 16 34
  • 82.91 (n)
Scd4 34
  • 78 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia SCD 34
  • 75 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SCD 34
  • 72 (a)
OneToOne
chicken
(Gallus gallus)
Aves SCD 33 34
  • 70.52 (n)
lizard
(Anolis carolinensis)
Reptilia SCD 34
  • 60 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia scd 33
  • 64.69 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.8660 33
zebrafish
(Danio rerio)
Actinopterygii scdb 33 34
  • 64.18 (n)
scd 33 34
  • 61 (a)
fruit fly
(Drosophila melanogaster)
Insecta desat1 35 34
  • 58 (a)
desat2 35 33 34
  • 56.69 (n)
CG9743 35 34
  • 53 (a)
CG8630 35 34
  • 50 (a)
Fad2 35 34
  • 50 (a)
CG9747 35 34
  • 49 (a)
CG15531 35 34
  • 29 (a)
worm
(Caenorhabditis elegans)
Secernentea fat-6 35 34
  • 53 (a)
fat-7 35 34
  • 53 (a)
fat-5 35 34
  • 46 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes OLE1 34 36
  • 22 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.9947 34
  • 47 (a)
ManyToMany
CSA.9813 34
  • 46 (a)
ManyToMany
-- 34
  • 43 (a)
ManyToMany
Species where no ortholog for SCD was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SCD Gene

ENSEMBL:
Gene Tree for SCD (if available)
TreeFam:
Gene Tree for SCD (if available)

Paralogs for SCD Gene

Paralogs for SCD Gene

(1) SIMAP similar genes for SCD Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for SCD Gene

genes like me logo Genes that share paralogs with SCD: view

Variants for SCD Gene

Sequence variations from dbSNP and Humsavar for SCD Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs1000077946 -- 100,358,254(+) CCTTG(A/G)CCTCC intron-variant
rs1000139666 -- 100,358,470(+) GCCTG(C/T)AGTCC intron-variant
rs1000503829 -- 100,346,017(+) CACAG(C/G)GACAG intron-variant, upstream-variant-2KB
rs1000527886 -- 100,345,854(+) AATCA(C/T)TGGCG intron-variant, upstream-variant-2KB
rs1000624603 -- 100,359,787(+) TTAGG(A/G)TCAGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SCD Gene

Variant ID Type Subtype PubMed ID
nsv519672 CNV gain 19592680
nsv527448 CNV gain 19592680
nsv831961 CNV loss 17160897
nsv948167 CNV duplication 23825009

Variation tolerance for SCD Gene

Residual Variation Intolerance Score: 19.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.71; 57.46% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SCD Gene

Human Gene Mutation Database (HGMD)
SCD
SNPedia medical, phenotypic, and genealogical associations of SNPs for
SCD

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SCD Gene

Disorders for SCD Gene

MalaCards: The human disease database

(3) MalaCards diseases for SCD Gene - From: HGMD, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
reye syndrome
  • reye's syndrome
obesity
  • obesity, association with
diabetes mellitus, noninsulin-dependent
  • diabetes, type 2
- elite association - COSMIC cancer census association via MalaCards
Search SCD in MalaCards View complete list of genes associated with diseases

Relevant External Links for SCD

Genetic Association Database (GAD)
SCD
Human Genome Epidemiology (HuGE) Navigator
SCD
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SCD
genes like me logo Genes that share disorders with SCD: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SCD Gene

Publications for SCD Gene

  1. Human stearoyl-CoA desaturase: alternative transcripts generated from a single gene by usage of tandem polyadenylation sites. (PMID: 10229681) Zhang L … Prouty SM (The Biochemical journal 1999) 2 3 4 22 60
  2. Characterization of HSCD5, a novel human stearoyl-CoA desaturase unique to primates. (PMID: 15907797) Wang J … Cao G (Biochemical and biophysical research communications 2005) 3 4 22 60
  3. Characterization of human SCD2, an oligomeric desaturase with improved stability and enzyme activity by cross-linking in intact cells. (PMID: 15610069) Zhang S … Shi Y (The Biochemical journal 2005) 3 4 22 60
  4. Analysis of the contribution to type 2 diabetes susceptibility of sequence variation in the gene encoding stearoyl-CoA desaturase, a key regulator of lipid and carbohydrate metabolism. (PMID: 15662557) Liew CF … McCarthy MI (Diabetologia 2004) 3 22 45 60
  5. Partial characterization of a cDNA for human stearoyl-CoA desaturase and changes in its mRNA expression in some normal and malignant tissues. (PMID: 7909540) Li J … Gilmour RS (International journal of cancer 1994) 2 3 4 60

Products for SCD Gene

Sources for SCD Gene

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