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Aliases for SCARNA4 Gene

Subcategory (RNA class) for SCARNA4 Gene

scaRNA

Quality Score for this RNA gene is

12

Aliases for SCARNA4 Gene

  • Small Cajal Body-Specific RNA 4 2 3 5
  • ACA26 ScaRNA 3
  • ACA26 3

External Ids for SCARNA4 Gene

Previous GeneCards Identifiers for SCARNA4 Gene

  • GC01M154162
  • GC01M155895
  • GC01M127256

Summaries for SCARNA4 Gene

GeneCards Summary for SCARNA4 Gene

SCARNA4 (Small Cajal Body-Specific RNA 4) is an RNA Gene, and is affiliated with the scaRNA class.

fRNAdb sequence ontologies for SCARNA4 Gene - the ORGUL cluster for this gene includes several descriptions:

  • snoRNA: A snoRNA (small nucleolar RNA) is any one of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins. They participate in the processing or modifications of many RNAs, mostly ribosomal RNAs (rRNAs) though snoRNAs are also known to target other classes of RNA, including spliceosomal RNAs, tRNAs, and mRNAs via a stretch of sequence that is complementary to a sequence in the targeted RNA.

  • Small Cajal body specific RNA 15: scaRNAs are a specific class of small nuclear RNAs which localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12 [1]. ACA45 belongs to the H/ACA box class of guide RNAs as it has the predicted hairpin-hinge-hairpin-tail structure, the conserved H/ACA-box motifs and is found associated with GAR1 [2]. ACA45 is predicted to guide the pseudouridylation of residue U37 of the U2 spliceosomal snRNA [2].

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SCARNA4 Gene

Genomics for SCARNA4 Gene

Regulatory Elements for SCARNA4 Gene

Enhancers for SCARNA4 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G155965 1.8 FANTOM5 ENCODE dbSUPER 12 -49.3 -49291 19.0 CREB3L1 MLX AGO1 ZFP64 DMAP1 FEZF1 SLC30A9 ZNF416 ZNF143 ZNF263 RIT1 ARHGEF2 PAQR6 KIAA0907 ASH1L RXFP4 SCARNA4 LAMTOR2 UBQLN4 THBS3
GH01G156000 1.5 Ensembl ENCODE dbSUPER 11.6 -76.4 -76393 3.6 HDGF FOXA2 CREB3L1 ARID4B SIN3A ZNF207 FOS ZNF263 JUNB SMARCB1 RIT1 RXFP4 KIAA0907 UBQLN4 LAMTOR2 SCARNA4 MEX3A LMNA SNORA80E GLMP
GH01G155960 1.4 Ensembl ENCODE dbSUPER 12.1 -35.0 -35044 4.4 NFIB INSM2 KLF17 SIN3A RAD21 ZNF121 RCOR1 FOS IKZF2 DEK RIT1 LOC107985210 ARHGEF2 KIAA0907 SCARNA4 LAMTOR2 UBQLN4 LOC107985209 MIR6738
GH01G155964 1.1 dbSUPER 12.1 -39.1 -39079 0.6 HDGF FOXA2 PKNOX1 ARNT CREB3L1 ARID4B SIN3A YY1 SLC30A9 ZNF766 KIAA0907 RIT1 RRNAD1 LOC107985210 ARHGEF2 RXFP4 ENSG00000271267 SCARNA4 LAMTOR2 UBQLN4
GH01G156006 1.1 ENCODE dbSUPER 11.6 -80.8 -80759 0.2 PKNOX1 NFRKB FEZF1 GLIS2 EGR1 ELK1 KLF7 RELB IKZF2 EGR2 RXFP4 KIAA0907 UBQLN4 LAMTOR2 SCARNA4 LMNA MEX3A SNORA80E GLMP ARHGEF2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SCARNA4 on UCSC Golden Path with GeneCards custom track

Genomic Location for SCARNA4 Gene

Chromosome:
1
Start:
155,925,958 bp from pter
End:
155,926,086 bp from pter
Size:
129 bases
Orientation:
Minus strand

Genomic View for SCARNA4 Gene

Genes around SCARNA4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SCARNA4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SCARNA4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SCARNA4 Gene

ORGUL Member Location for SCARNA4 Gene

ORGUL Member Location for SCARNA4 gene

Proteins for SCARNA4 Gene

Post-translational modifications for SCARNA4 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SCARNA4 Gene

Domains & Families for SCARNA4 Gene

Gene Families for SCARNA4 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SCARNA4: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SCARNA4 Gene

Function for SCARNA4 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SCARNA4 Gene

Localization for SCARNA4 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SCARNA4 Gene

Pathways & Interactions for SCARNA4 Gene

SuperPathways for SCARNA4 Gene

No Data Available

Interacting Proteins for SCARNA4 Gene

Gene Ontology (GO) - Biological Process for SCARNA4 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SCARNA4 Gene

Transcripts for SCARNA4 Gene

mRNA/cDNA for SCARNA4 Gene

(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SCARNA4 Gene

Small Cajal body-specific RNA 4:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SCARNA4 Gene

No ASD Table

Relevant External Links for SCARNA4 Gene

GeneLoc Exon Structure for
SCARNA4
ECgene alternative splicing isoforms for
SCARNA4

Expression for SCARNA4 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SCARNA4 Gene

NURSA nuclear receptor signaling pathways regulating expression of SCARNA4 Gene:

SCARNA4

SOURCE GeneReport for Unigene cluster for SCARNA4 Gene:

Hs.678903
genes like me logo Genes that share expression patterns with SCARNA4: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SCARNA4 Gene

Orthologs for SCARNA4 Gene

Evolution for SCARNA4 Gene

ENSEMBL:
Gene Tree for SCARNA4 (if available)
TreeFam:
Gene Tree for SCARNA4 (if available)

No data available for Orthologs for SCARNA4 Gene

Paralogs for SCARNA4 Gene

No data available for Paralogs for SCARNA4 Gene

Variants for SCARNA4 Gene

Sequence variations from dbSNP and Humsavar for SCARNA4 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1001258993 -- 155,927,807(+) CCAAA(A/G)AAAAA intron-variant, upstream-variant-2KB
rs1001697220 -- 155,926,295(+) CACGA(C/T)TTTTT intron-variant, upstream-variant-2KB
rs1007870728 -- 155,927,097(+) AACAT(C/T)ACTTA intron-variant, upstream-variant-2KB
rs1009887704 -- 155,927,565(+) TTTGG(A/G)AGGCT intron-variant, upstream-variant-2KB
rs1010048756 -- 155,926,274(+) CGGGA(C/T)TGGAA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SCARNA4 Gene

Variant ID Type Subtype PubMed ID
esv33869 CNV loss 17666407

Relevant External Links for SCARNA4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SCARNA4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SCARNA4 Gene

Disorders for SCARNA4 Gene

Relevant External Links for SCARNA4

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SCARNA4

No disorders were found for SCARNA4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SCARNA4 Gene

Publications for SCARNA4 Gene

  1. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss A.M. … Kiss T. (Mol. Cell. Biol. 2004) 1 3 64
  2. Cajal body-specific small nuclear RNAs: a novel class of 2'-O-methylation and pseudouridylation guide RNAs. (PMID: 12032087) Darzacq X. … Kiss T. (EMBO J. 2002) 1 3 64
  3. A common sequence motif determines the Cajal body-specific localization of box H/ACA scaRNAs. (PMID: 12912925) Richard P. … Kiss T. (EMBO J. 2003) 3 64
  4. The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. (PMID: 18089548) . … Gojobori T. (Nucleic Acids Res. 2008) 1
  5. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L. … Weber M.J. (Nucleic Acids Res. 2006) 1

Products for SCARNA4 Gene

Sources for SCARNA4 Gene

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