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Aliases for SCARNA22 Gene

Subcategory (RNA class) for SCARNA22 Gene

scaRNA

Quality Score for this RNA gene is

3

Aliases for SCARNA22 Gene

  • Small Cajal Body-Specific RNA 22 2 3 5
  • ACA11 SnoRNA 3
  • ACA11 3

External Ids for SCARNA22 Gene

Previous GeneCards Identifiers for SCARNA22 Gene

  • GC04P001946
  • GC04P001977

Summaries for SCARNA22 Gene

GeneCards Summary for SCARNA22 Gene

SCARNA22 (Small Cajal Body-Specific RNA 22) is an RNA Gene, and is affiliated with the scaRNA class.

Additional gene information for SCARNA22 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SCARNA22 Gene

Genomics for SCARNA22 Gene

GeneHancer (GH) Regulatory Elements for SCARNA22 Gene

Promoters and enhancers for SCARNA22 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH04I002007 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 12.2 +34.6 34570 3.2 HDGF PKNOX1 FOXA2 ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 IRF4 NELFA NOP14-AS1 MAEA SCARNA22 C4orf48 SH3BP2 NSD2 MXD4 ENSG00000251148 ZFYVE28
GH04I002011 Enhancer 0.5 Ensembl 11.9 +37.2 37154 0.5 ATF4 HLF CEBPA CEBPB ZNF384 CEBPG C4orf48 NELFA SCARNA22 NSD2 MXD4 ENSG00000250623 ENSG00000251148 ZFYVE28 HAUS3 POLN
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SCARNA22 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SCARNA22 gene promoter:

Genomic Locations for SCARNA22 Gene

Genomic Locations for SCARNA22 Gene
chr4:1,974,636-1,974,760
(GRCh38/hg38)
Size:
125 bases
Orientation:
Plus strand
chr4:1,976,363-1,976,487
(GRCh37/hg19)

Genomic View for SCARNA22 Gene

Genes around SCARNA22 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SCARNA22 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SCARNA22 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SCARNA22 Gene

Proteins for SCARNA22 Gene

Post-translational modifications for SCARNA22 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SCARNA22 Gene

Domains & Families for SCARNA22 Gene

Gene Families for SCARNA22 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SCARNA22: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SCARNA22 Gene

Function for SCARNA22 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SCARNA22 Gene

Localization for SCARNA22 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SCARNA22 Gene

Pathways & Interactions for SCARNA22 Gene

SuperPathways for SCARNA22 Gene

No Data Available

Interacting Proteins for SCARNA22 Gene

Gene Ontology (GO) - Biological Process for SCARNA22 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SCARNA22 Gene

Drugs & Compounds for SCARNA22 Gene

No Compound Related Data Available

Transcripts for SCARNA22 Gene

mRNA/cDNA for SCARNA22 Gene

(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SCARNA22 Gene

Small Cajal body-specific RNA 22:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SCARNA22 Gene

No ASD Table

Relevant External Links for SCARNA22 Gene

GeneLoc Exon Structure for
SCARNA22
ECgene alternative splicing isoforms for
SCARNA22

Expression for SCARNA22 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SCARNA22 Gene

mRNA differential expression in normal tissues according to GTEx for SCARNA22 Gene

This gene is overexpressed in Testis (x4.5).

NURSA nuclear receptor signaling pathways regulating expression of SCARNA22 Gene:

SCARNA22

SOURCE GeneReport for Unigene cluster for SCARNA22 Gene:

Hs.676951
genes like me logo Genes that share expression patterns with SCARNA22: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SCARNA22 Gene

Orthologs for SCARNA22 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SCARNA22 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SCARNA23 34
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm22728 34
  • 82 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SCARNA23 34
  • 81 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SCARNA23 34
  • 81 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SCARNA23 34
  • 69 (a)
OneToOne
chicken
(Gallus gallus)
Aves SCARNA23 34
  • 62 (a)
OneToOne
Species where no ortholog for SCARNA22 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SCARNA22 Gene

ENSEMBL:
Gene Tree for SCARNA22 (if available)
TreeFam:
Gene Tree for SCARNA22 (if available)

Paralogs for SCARNA22 Gene

No data available for Paralogs for SCARNA22 Gene

Variants for SCARNA22 Gene

Sequence variations from dbSNP and Humsavar for SCARNA22 Gene

SNP ID Clin Chr 04 pos Variation AA Info Type
rs138946638 likely-benign, 4p partial monosomy syndrome 1,974,964(+) C/T downstream_transcript_variant
rs73069117 likely-benign, 4p partial monosomy syndrome 1,974,985(+) C/T downstream_transcript_variant
rs886059319 uncertain-significance, 4p partial monosomy syndrome 1,974,976(+) C/T downstream_transcript_variant
rs1001068443 -- 1,972,670(+) T/C/G upstream_transcript_variant
rs1003486993 -- 1,974,198(+) T/C upstream_transcript_variant

Additional Variant Information for SCARNA22 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SCARNA22

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for SCARNA22 Gene

Disorders for SCARNA22 Gene

Additional Disease Information for SCARNA22

No disorders were found for SCARNA22 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SCARNA22 Gene

Publications for SCARNA22 Gene

  1. An updated human snoRNAome. (PMID: 27174936) Jorjani H … Gruber AR (Nucleic acids research 2016) 3 58
  2. Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress. (PMID: 22751105) Chu L … Tomasson MH (The Journal of clinical investigation 2012) 3 58
  3. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss AM … Kiss T (Molecular and cellular biology 2004) 3 58

Products for SCARNA22 Gene

Sources for SCARNA22 Gene

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