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SCARF2 Gene

protein-coding   GIFtS: 51
GCID: GC22M020778

Scavenger Receptor Class F, Member 2

  See SCARF2-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Scavenger Receptor Class F, Member 21 2     VDEGS2 5
SREC22 3 5     NSR12
Scavenger Receptor Expressed By Endothelial Cells 2 Protein2 3     Scavenger Receptor Class F Member 22
SREC-II2 3     SREPCR3
SRECRP-12 3     

External Ids:    HGNC: 198691   Entrez Gene: 911792   Ensembl: ENSG000002444867   OMIM: 6136195   UniProtKB: Q96GP63   

Export aliases for SCARF2 gene to outside databases

Previous GC identifers: GC22M017481 GC22M019103 GC22M004042


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SCARF2 Gene:
The protein encoded by this gene is similar to SCARF1/SREC-I, a scavenger receptor protein that mediates the
binding and degradation of acetylated low density lipoprotein (Ac-LDL). This protein has only little activity of
internalizing modified low density lipoproteins (LDL), but it can interact with SCARF1 through its extracellular
domain. The association of this protein with SCARF1 is suppressed by the presence of scavenger ligands.
Alternatively spliced transcript variants encoding distinct isoforms have been reported. (provided by RefSeq, Jul
2008)

GeneCards Summary for SCARF2 Gene:
SCARF2 (scavenger receptor class F, member 2) is a protein-coding gene. Diseases associated with SCARF2 include marden walker like syndrome, and histidinemia. GO annotations related to this gene include scavenger receptor activity. An important paralog of this gene is SCARF1.

UniProtKB/Swiss-Prot: SREC2_HUMAN, Q96GP6
Function: Probable adhesion protein, which mediates homophilic and heterophilic interactions. In contrast to
SCARF1, it poorly mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL) (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000022.10  NT_011520.13  NC_018933.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SCARF2 gene promoter:
         AhR   GR   Sp1   p300   GR-beta   Nkx2-5   Arnt   POU2F1   POU2F1a   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSCARF2 promoter sequence
   Search Chromatin IP Primers for SCARF2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SCARF2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q11.21   Ensembl cytogenetic band:  22q11.21   HGNC cytogenetic band: 22q11.21

SCARF2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SCARF2 gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22M020778:  view genomic region     (about GC identifiers)

Start:
20,778,874 bp from pter      End:
20,792,146 bp from pter
Size:
13,273 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SREC2_HUMAN, Q96GP6 (See protein sequence)
Recommended Name: Scavenger receptor class F member 2 precursor  
Size: 870 amino acids; 92479 Da
Subunit: Homophilic and heterophilic interaction via its extracellular domain. Interacts with SCARF1. The
heterophilic interaction with SCARF1, which is stronger than the homophilic interaction with itself, is
suppressed by the presence of SCARF1 ligand such as Ac-LDL (By similarity)
Caution: The conflict at position 750-768 is due to frameshifts. The frameshifted sequence is found in mouse
Secondary accessions: E5RFB8 Q58A83 Q8IXF3 Q9BW74
Alternative splicing: 2 isoforms:  Q96GP6-1   Q96GP6-2   

Explore the universe of human proteins at neXtProt for SCARF2: NX_Q96GP6

Explore proteomics data for SCARF2 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn83, Asn310, Asn365, Asn403
  • Modification sites at PhosphoSitePlus

  • See SCARF2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_699165.3  NP_878315.2  

    ENSEMBL proteins: 
     ENSP00000385589   ENSP00000266214  

    SCARF2 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR000742 EG-like_dom
     IPR002049 EGF_laminin
     IPR009030 Growth_fac_rcpt_N_dom
     IPR013032 EGF-like_CS

    Graphical View of Domain Structure for InterPro Entry Q96GP6

    ProtoNet protein and cluster: Q96GP6

    3 Blocks protein domains:
    IPB002049 Laminin-type EGF-like domain
    IPB006210 Type I EGF
    IPB013111 EGF


    UniProtKB/Swiss-Prot: SREC2_HUMAN, Q96GP6
    Similarity: Contains 7 EGF-like domains


    Find genes that share domains with SCARF2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SREC2_HUMAN, Q96GP6
    Function: Probable adhesion protein, which mediates homophilic and heterophilic interactions. In contrast to
    SCARF1, it poorly mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL) (By
    similarity)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005044scavenger receptor activity IEA--
    GO:0005515protein binding IPI17474147
         
    Find genes that share ontologies with SCARF2           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for SCARF2:
     Decreased Wnt reporter activit  Decreased nuclei size in G2M 

         1 MGI phenotypic allele for Scarf2 (no phenotypes)

    Find genes that share phenotypes with SCARF2           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SCARF2
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    hsa-miR-125a-5p hsa-miR-548s hsa-miR-548o hsa-miR-4290 hsa-miR-548aa hsa-miR-2355-5p hsa-miR-544b hsa-miR-1323
    SwitchGear 3'UTR luciferase reporter plasmidSCARF2 3' UTR sequence
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    Predesigned siRNA for gene silencing in human, mouse, rat SCARF2

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SREC2_HUMAN, Q96GP6: Membrane; Single-pass type I membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    cytosol1
    endoplasmic reticulum1
    golgi apparatus1
    nucleus1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with SCARF2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SCARF2
    Interactions:

        Search GeneGlobe Interaction Network for SCARF2

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5 Interacting proteins for SCARF2 (Q96GP61, 2, 3 ENSP000002662144) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ABL1P005192, 3, ENSP000003614234MINT-8110803 I2D: score=3 STRING: ENSP00000361423
    NCK1P163331, 3, ENSP000002889864EBI-1752088,EBI-389883 I2D: score=2 STRING: ENSP00000288986
    FYNP062413, ENSP000003576564I2D: score=2 STRING: ENSP00000357656
    SCARF1Q141623, ENSP000002630714I2D: score=1 STRING: ENSP00000263071
    GRB2P629933, ENSP000003390074I2D: score=2 STRING: ENSP00000339007
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007157heterophilic cell-cell adhesion IEA--

    Find genes that share ontologies with SCARF2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SCARF2 (SREC2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SCARF2 gene (2 alternative transcripts): 
    NM_153334.6  NM_182895.4  

    Unigene Cluster for SCARF2:

    Scavenger receptor class F, member 2
    Hs.474251  [show with all ESTs]
    Unigene Representative Sequence: NM_153334
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000405555(uc002zsj.2 uc002zsk.2) ENST00000266214 ENST00000494535

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate SCARF2 (see all 13):
    hsa-miR-125a-5p hsa-miR-548s hsa-miR-548o hsa-miR-4290 hsa-miR-548aa hsa-miR-2355-5p hsa-miR-544b hsa-miR-1323
    SwitchGear 3'UTR luciferase reporter plasmidSCARF2 3' UTR sequence
    Inhib. RNA
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    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SCARF2
      QuantiTect SYBR Green Assays in human, mouse, rat SCARF2
      QuantiFast Probe-based Assays in human, mouse, rat SCARF2

    Additional mRNA sequence: 

    AB024433.1 AB052951.1 AF088043.1 AF522196.1 BC000584.2 BC009326.2 

    6 DOTS entries:

    DT.100742073  DT.452973  DT.101977829  DT.100024208  DT.100024209  DT.95299041 

    Selected AceView cDNA sequences (see all 354):

    AI912007 NM_182895 AF088043 BG105986 BC015923 BF196914 CK824857 CR610643 
    BM663549 BU541355 AW136571 AA069102 BX345275 CR601347 AI949809 AI083921 
    AI338167 BX282290 AI467996 AK027266 AA256005 CR593866 BM768496 CA433979 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SCARF2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGGCCGCTG
    SCARF2 Expression
    About this image

    SCARF2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SCARF2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.474251

    UniProtKB/Swiss-Prot: SREC2_HUMAN, Q96GP6
    Tissue specificity: Predominantly expressed in endothelial cells. Expressed in heart, placenta, lung, kidney,
    spleen, small intestine and ovary

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SCARF2 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Scarf21 , 5 scavenger receptor class F, member 21, 5 83.45(n)1
    85.84(a)1
      16 (11.03 cM)5
    2240241  NM_153790.21  NP_722485.11 
     177972825 
    chicken
    (Gallus gallus)
    Aves SCARF21 scavenger receptor class F, member 2 68.44(n)
    66.25(a)
      772263  XM_001235424.3  XP_001235425.3 
    lizard
    (Anolis carolinensis)
    Reptilia SCARF26
    scavenger receptor class F, member 2
    58(a)
    1 ↔ 1
    GL343417.1(760187-777215)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia LOC1004856661 scavenger receptor class F member 2-like 56.76(n)
    58.83(a)
      100485666  XM_002932102.2  XP_002932148.2 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003296321 scavenger receptor class F member 2-like 56.03(n)
    52.19(a)
      100329632  XM_003198601.2  XP_003198649.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta nimA6
    nimrod A
    17(a)
    1 → many
    2L(13957539-13963381)


    ENSEMBL Gene Tree for SCARF2 (if available)
    TreeFam Gene Tree for SCARF2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SCARF2 gene
    SCARF12  MEGF112  PEAR12  MEGF102  
    1 SIMAP similar gene for SCARF2 using alignment to 1 protein entry:     SREC2_HUMAN:
    SCARF1

    Find genes that share paralogs with SCARF2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SCARF2 (see all 364)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0358374
    A breast cancer sample4--see VAR_0358372 R C mis40--------
    VAR_0653024
    Van den Ende-Gupta syndrome (VDEGS)4--see VAR_0653022 C Y mis40--------
    rs1512537101,2
    --4720695(+) AGACCA/GGCTTG 2 -- ds50010--------
    rs102120801,2
    C,F--4720716(+) AGGAGG/ACCCGG 2 -- ds50013Minor allele frequency- A:0.19WA NA EA 358
    rs102120531,2
    C,F--4720717(+) GGAGGC/ACCGGC 2 -- ds50013Minor allele frequency- A:0.18WA NA EA 358
    rs10764861,2
    C,F,H--4721039(-) TCAGCG/AGGGAG 2 -- ds500116Minor allele frequency- A:0.29NS EA CSA NA 3323
    rs1404732191,2
    --4721189(+) CCCGCC/TGGGAG 2 -- ut310--------
    rs1445432821,2
    C--4721349(+) TGGGCC/TCGGGG 2 -- ut310--------
    rs1466288811,2
    --4721485(+) GGGACA/GGCCAA 2 -- ut310--------
    rs1855362591,2
    --4721497(+) GGAGGC/GAGCCT 2 -- ut310--------

    HapMap Linkage Disequilibrium report for SCARF2 (20778874 - 20792146 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for SCARF2 (see all 17):    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv436864CNV Insertion17901297
    nsv436867CNV Insertion17901297
    nsv509809CNV Insertion20534489
    dgv4868n71CNV Loss21882294
    nsv834138CNV Loss17160897
    nsv914401CNV Loss21882294
    nsv523162CNV Loss19592680
    nsv914400CNV Loss21882294
    nsv834136CNV Loss17160897
    nsv828955CNV Gain20364138

    Human Gene Mutation Database (HGMD): SCARF2
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SCARF2
    DNA2.0 Custom Variant and Variant Library Synthesis for SCARF2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 613619   
    OMIM disorders: 600920  
    UniProtKB/Swiss-Prot: SREC2_HUMAN, Q96GP6
  • Van den Ende-Gupta syndrome (VDEGS) [MIM:600920]: A syndrome characterized by craniofacial and skeletal
    abnormalities that include blepharophimosis, a flat and wide nasal bridge, narrow and beaked nose, hypoplastic
    maxilla with or without cleft palate and everted lower lip, prominent ears, down-slanting eyes, arachnodactyly,
    and camptodactyly. Patients present congenital joint contractures that improve without intervention, and normal
    growth and development. Intelligence is normal. Rarely, enlarged cerebella can be present. Some patients
    experience respiratory problems due to laryngeal abnormalities. Note=The disease is caused by mutations affecting
    the gene represented in this entry

  • 2 diseases for SCARF2:    
    About MalaCards
    marden walker like syndrome    histidinemia


    Find genes that share disorders with SCARF2           About GenesLikeMe

    Genetic Association Database (GAD): SCARF2
    Human Genome Epidemiology (HuGE) Navigator: SCARF2 (1 document)

    Export disorders for SCARF2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SCARF2 gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with SCARF2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. SREC-II, a new member of the scavenger receptor type F family, trans- interacts with SREC-I through its extracellular domain. (PubMed id 12154095)1, 2, 3 Ishii J.... Arai H. (J. Biol. Chem. 2002)
    2. Mutations in SCARF2 are responsible for Van Den Ende-Gupta syndrome. (PubMed id 20887961)1, 2 Anastasio N.... Jerome-Majewska L.A. (Am. J. Hum. Genet. 2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    5. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    6. Single-nucleotide polymorphisms, acute rejection, and severity of tubulitis in kidney transplantation, accounting for center-to-center variation. (PubMed id 21085059)4 Israni A....Oetting W.S. (Transplantation 2010)
    7. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (Anal. Chem. 2009)
    8. Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. (PubMed id 17474147)1 Wu C....Li S.S. (Proteomics 2007)
    9. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (Science 2006)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 91179 HGNC: 19869 AceView: SCARF2andKELCHL Ensembl:ENSG00000244486 euGenes: HUgn91179
    ECgene: SCARF2 H-InvDB: SCARF2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SCARF2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SCARF2 gene:
    Search GeneIP for patents involving SCARF2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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