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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SCARF1 Gene

protein-coding   GIFtS: 58
GCID: GC17M001537

Scavenger Receptor Class F, Member 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Scavenger Receptor Class F, Member 11 2     KIAA01493 5
Acetyl LDL Receptor1 2 3     Scavenger Receptor Expressed By Endothelial Cells1
SREC2 3 5     SREC12
Scavenger Receptor Expressed By Endothelial Cells 12 3     Scavenger Receptor Class F Member 12
SREC-I2 3     

External Ids:    HGNC: 168201   Entrez Gene: 85782   Ensembl: ENSG000000746607   OMIM: 6078735   UniProtKB: Q141623   
ORGUL members:         
NONCODE14:n408129 n408130      

Export aliases for SCARF1 gene to outside databases

Previous GC identifers: GC17P001630 GC17M001872 GC17M001487 GC17M001743 GC17M001484 GC17M001485 GC17M001436


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SCARF1 Gene:
The protein encoded by this gene is a scavenger receptor that is expressed in endothelial cells. It regulates the
uptake of chemically modified low density lipoproteins, including acetylated low density lipoprotein (Ac-LDL),
and it may be involved in atherogenesis. This gene is regulated by the transcription factors ZNF444/EZF-2 and
SP1. Alternative splicing results in multiple transcript variants. (provided by RefSeq, Apr 2013)

GeneCards Summary for SCARF1 Gene: 
SCARF1 (scavenger receptor class F, member 1) is a protein-coding gene, and is affiliated with the lncRNA class. Diseases associated with SCARF1 include endotheliitis, and peritonitis, and among its related super-pathways are Scavenging of Heme from Plasma. GO annotations related to this gene include low-density lipoprotein particle binding and transmembrane signaling receptor activity. An important paralog of this gene is MEGF11.

UniProtKB/Swiss-Prot: SREC_HUMAN, Q14162
Function: Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates
heterophilic interactions, suggesting a function as adhesion protein. Plays a role in the regulation of
neurite-like outgrowth (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.2  NT_010718.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SCARF1 gene promoter:
         AML1a   Tal-1   Lmo2   NF-E2 p45   Nkx5-1   E47   c-Ets-1   ZID   NF-E2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSCARF1 promoter sequence
   Search SABiosciences Chromatin IP Primers for SCARF1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SCARF1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.3   Ensembl cytogenetic band:  17p13.3   HGNC cytogenetic band: 17p13.3

SCARF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SCARF1 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M001537:  view genomic region     (about GC identifiers)

Start:
1,537,152 bp from pter      End:
1,549,041 bp from pter
Size:
11,890 bases      Orientation:
minus strand
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for SCARF1

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SREC_HUMAN, Q14162 (See protein sequence)
Recommended Name: Scavenger receptor class F member 1 precursor  
Size: 830 amino acids; 87387 Da
Subunit: Heterophilic interaction with SREC2 via its extracellular domain. The heterophilic interaction is
suppressed by the presence of ligand such as Ac-LDL. Interacts with AVIL (By similarity)
Subcellular location: Membrane; Single-pass type I membrane protein (Potential)
Secondary accessions: A8MQ05 O43701 Q8NHD2 Q8NHD3 Q8NHD4 Q8NHD5
Alternative splicing: 5 isoforms:  Q14162-1   Q14162-2   Q14162-3   Q14162-4   Q14162-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SCARF1: NX_Q14162

Explore proteomics data for SCARF1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q14162

  • SCARF1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SCARF1 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_003684.2  NP_663325.1  

    ENSEMBL proteins: 
     ENSP00000263071   ENSP00000411167   ENSP00000458174   ENSP00000461468   ENSP00000323964  
    Reactome Protein details: Q14162
    Human Recombinant Protein Products for SCARF1: 
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    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SCARF1 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016021integral to membrane IDA9395444
    GO:0030666endocytic vesicle membrane TAS--

    SCARF1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR000742 EG-like_dom
     IPR009030 Growth_fac_rcpt_N_dom
     IPR013032 EGF-like_CS
     IPR002049 EGF_laminin

    Graphical View of Domain Structure for InterPro Entry Q14162

    ProtoNet protein and cluster: Q14162

    1 Blocks protein domain: IPB006210 Type I EGF

    UniProtKB/Swiss-Prot: SREC_HUMAN, Q14162
    Similarity: Contains 6 EGF-like domains


    SCARF1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SREC_HUMAN, Q14162
    Function: Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates
    heterophilic interactions, suggesting a function as adhesion protein. Plays a role in the regulation of
    neurite-like outgrowth (By similarity)

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004888transmembrane signaling receptor activity TAS9395444
    GO:0005044scavenger receptor activity IDA9395444
    GO:0005515protein binding ----
    GO:0030169low-density lipoprotein particle binding IDA9395444
         
    SCARF1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SCARF1:
     Synthetic lethal with Ras 

         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Scarf1):
     immune system  normal 

    SCARF1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Scarf1tm1Ishi for SCARF1

       inGenious Targeting Laboratory - Custom generated mouse model solutions for SCARF1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SCARF1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SCARF1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SCARF1 

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    8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate SCARF1 (see all 9):
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    SwitchGear 3'UTR luciferase reporter plasmidSCARF1 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCARF1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SCARF1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Binding and Uptake of Ligands by Scavenger Receptors
    Binding and Uptake of Ligands by Scavenger Receptors0.63
    2Scavenging by Class F Receptors
    Scavenging by Class F Receptors

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2        Reactome Pathways for SCARF1
        Scavenging by Class F Receptors
    Binding and Uptake of Ligands by Scavenger Receptors



    SCARF1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SCARF1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for SCARF1 (Q141623 ENSP000002630714) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CALRP277973, ENSP000003208664I2D: score=1 STRING: ENSP00000320866
    SCARF2Q96GP63, ENSP000002662144I2D: score=1 STRING: ENSP00000266214
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006707cholesterol catabolic process IC9395444
    GO:0006898receptor-mediated endocytosis TAS9395444
    GO:0007155cell adhesion IEA--
    GO:0010976positive regulation of neuron projection development ISS--
    GO:0016322neuron remodeling ISS--

    SCARF1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SCARF1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SCARF1 (SREC)

    2 Novoseek inferred chemical compound relationships for SCARF1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    fucoidan 72.7 1 1574712 (1)
    lipid 0 1 7755626 (1)

    Search CenterWatch for drugs/clinical trials and news about SCARF1 / SREC

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SCARF1 gene (3 alternative transcripts): 
    NM_003693.3  NM_145350.2  NM_145352.2  

    Unigene Cluster for SCARF1:

    Scavenger receptor class F, member 1
    Hs.647430  [show with all ESTs]
    Unigene Representative Sequence: NR_028076
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000263071(uc002fsy.1 uc002fsz.1 uc002fta.1) ENST00000434376
    ENST00000576012 ENST00000571272 ENST00000573852 ENST00000570902 ENST00000574545
    ENST00000573867 ENST00000348987(uc010cjv.1)
    miRNA
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    8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate SCARF1 (see all 9):
    hsa-miR-4307 hsa-miR-2114 hsa-miR-19b-2* hsa-miR-3922-3p hsa-miR-33a* hsa-miR-19b-1* hsa-miR-19a* hsa-miR-3176
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    Inhib. RNA
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    Additional mRNA sequence: 

    AB052947.1 AB052948.1 AB052949.1 AB052950.1 AK291810.1 AK298737.1 AK308904.1 AK310174.1 
    AK311370.1 BC039735.1 D63483.1 D86864.1 NR_028075.1 NR_028076.1 

    7 DOTS entries:

    DT.207478  DT.101981342  DT.100017293  DT.100017291  DT.100060372  DT.92416552  DT.100058307 

    24/32 AceView cDNA sequences (see all 32):

    BX107630 AI690686 AL541679 NM_145351 CA434049 NM_145350 NM_003693 NM_145349 
    NM_145352 AB052947 AB052948 BQ719167 AI623132 BC039735 AB052949 AL046076 
    AA359329 AB052950 D63483 D86864 AI689097 AA369254 CF594207 BX418466 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SCARF1 expression in normal human tissues (normalized intensities)      SCARF1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTTGCTGATA
    SCARF1 Expression
    About this image


    SCARF1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Endothelium (Cardiovascular System)
             cd31+ cells   
     
     Bone (Muscoskeletal System)
             Zeugopod Periosteum
     
     Blood (Cardiovascular System)
             cd31+ cells   
     
     Thyroid (Endocrine System)

    See SCARF1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SCARF1

    SOURCE GeneReport for Unigene cluster: Hs.647430

    UniProtKB/Swiss-Prot: SREC_HUMAN, Q14162
    Tissue specificity: Endothelial cells

        SABiosciences Expression via Pathway-Focused PCR Arrays including SCARF1: 
              Lipoprotein Signaling & Cholesterol Metabolism in human mouse rat
              Antifungal Response in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCARF1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SCARF1 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Scarf11 , 5 scavenger receptor class F, member 11, 5 78.08(n)1
    72.64(a)1
      11 (45.92 cM)5
    3807131  NM_001004157.21  NP_001004157.21 
     755135405 
    chicken
    (Gallus gallus)
    Aves SCARF11 scavenger receptor class F, member 1 60.61(n)
    53.26(a)
      771559  XM_001234822.2  XP_001234823.2 
    lizard
    (Anolis carolinensis)
    Reptilia SCARF16
    Uncharacterized protein
    44(a)
    1 ↔ 1
    GL343393.1(172775-181462)
    African clawed frog
    (Xenopus laevis)
    Amphibia BI449460.12   -- 77.32(n)    BI449460.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1000052731 endothelial cells scavenger receptor-like 52.46(n)
    46.15(a)
      100005273  XM_001344339.2  XP_001344375.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta nimA6
    nimrod A
    13(a)
    1 → many
    2L(13957539-13963381)


    ENSEMBL Gene Tree for SCARF1 (if available)
    TreeFam Gene Tree for SCARF1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SCARF1 gene
    MEGF112  PEAR12  MEGF102  SCARF22  
    2 SIMAP similar genes for SCARF1 using alignment to 4 protein entries:     SREC_HUMAN (see all proteins):
    PEAR1    SCARF2

    SCARF1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/402 SNPs in SCARF1 are shown (see all 402)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1856193021,2
    --1536704(+) CGGGCA/GCGGTG 4 -- ds50010--------
    rs1389508941,2
    --1536705(+) GGGCGC/TGGTGG 4 -- ds50010--------
    rs356783631,2
    C,F--1536882(+) CTGAGG/ACAGGA 4 -- ds50013Minor allele frequency- A:0.50NA 6
    rs1436679401,2
    --1536901(+) TGAACC/TGGGGA 4 -- ds50010--------
    rs1481047291,2
    --1536927(+) GAGCCA/GAGATC 4 -- ds50010--------
    rs614054501,2
    C--1536978(+) ATCTT-/AAAAAA 4 -- ds50012Minor allele frequency- A:0.00NA CSA 4
    rs1888611771,2
    --1537058(+) TTCAAA/CCAAGA 4 -- ds50010--------
    rs358744811,2
    C,F,H--1537078(+) TGCCAG/AGGAAA 4 -- ds500111Minor allele frequency- A:0.01NS NA 1448
    rs1471915701,2
    --1537115(+) ACAGAC/TGCCTC 4 -- ds50010--------
    rs1817160101,2
    --1537395(+) AAAAGA/TTCATA 4 -- ut31 nc-transcript-variant0--------

    HapMap Linkage Disequilibrium report for SCARF1 (1537152 - 1549041 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/11 variations for SCARF1 (see all 11):    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv907515CNV Loss21882294
    nsv907511CNV Loss21882294
    nsv907502CNV Loss21882294
    dgv3032n71CNV Loss21882294
    nsv907513CNV Loss21882294
    dgv3031n71CNV Loss21882294
    nsv827855CNV Loss20364138
    nsv907517CNV Loss21882294
    nsv527897CNV Loss19592680
    nsv457635CNV Gain19166990

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607873    OMIM disorders: --

    4 diseases for SCARF1:    About MalaCards
    endotheliitis    peritonitis    malaria    neuronitis


    SCARF1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SCARF1
    Human Genome Epidemiology (HuGE) Navigator: SCARF1 (1 document)

    Export disorders for SCARF1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SCARF1 gene, integrated from 9 sources (see all 36):
    (articles sorted by number of sources associating them with SCARF1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Expression cloning of a novel scavenger receptor from human endothelial cells. (PubMed id 9395444)1, 2, 3 Adachi H.... Inoue K. (1997)
    2. Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 8590280)1, 2, 3 Nagase T....Nomura N. (1995)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Characterization of the human gene encoding the scavenger receptor expressed by endothelial cell and its regulation by a novel transcription factor, endothelial zinc finger protein-2. (PubMed id 11978792)1, 2 Adachi H. and Tsujimoto M. (2002)
    5. N-glycans of SREC-I (scavenger receptor expressed by e ndothelial cells): essential role for ligand binding, trafficking and stability. (PubMed id 22279061)1 Sano M....Taniguchi N. (2012)
    6. The zymogen granule protein 2 (GP2) binds to scavenge r receptor expressed on endothelial cells I (SREC-I). (PubMed id 21190681)1 HAPlzl M.A....Zlabinger G.J. (2011)
    7. Single-nucleotide polymorphisms, acute rejection, and severity of tubulitis in kidney transplantation, accounting for center-to-center variation. (PubMed id 21085059)4 Israni A....Oetting W.S. (2010)
    8. Heat shock protein 90 mediates efficient antigen cross presentation through the scavenger receptor expressed by endothelial cells-I. (PubMed id 20686127)1 Murshid A....Calderwood S.K. (2010)
    9. The scavenger receptors SRA-1 and SREC-I cooperate wi th TLR2 in the recognition of the hepatitis C virus non-structural protein 3 by dendritic cells. (PubMed id 20338659)1 Beauvillain C....Jeannin P. (2010)
    10. Oligo-guanosine nucleotide induces neuropilin-1 intern alization in endothelial cells and inhibits angiogenesis. (PubMed id 20606164)1 Narazaki M....Tosato G. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8578 HGNC: 16820 AceView: SCARF1 Ensembl:ENSG00000074660 euGenes: HUgn8578
    ECgene: SCARF1 H-InvDB: SCARF1

    (According to HUGE)
    About This Section
    HUGE: KIAA0149

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SCARF1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SCARF1 gene:
    Search GeneIP for patents involving SCARF1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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