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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SCARB2 Gene

protein-coding   GIFtS: 60
GCID: GC04M077079

scavenger receptor class B, member 2

(Previous names: CD36 antigen (collagen type I receptor, thrombospondin...)
(Previous symbol: CD36L2)
 Explore 30 diseases affiliated with
SCARB2 via our new
 Human Malady Compendium 
Biological research products
for SCARB2
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Scavenger Receptor Class B, Member 21 2     LGP852 3
CD36L21 2 3 5     CD36 Antigen-Like 22 3
LIMPII1 2 3 5     LIMP II2 3
HLGP851 2     AMRF2 5
LIMP-21 2     85 KDa Lysosomal Sialoglycoprotein Scavenger Receptor Class B, Member 22
SR-BII1 2     EPM42
CD36 Antigen (Collagen Type I Receptor, Thrombospondin Receptor)-Like 2
(Lysosomal Integral Membrane Protein II)1 2
     Lysosome Membrane Protein 22
Lysosome Membrane Protein II2 3     CD36 Antigen3
85 KDa Lysosomal Membrane Sialoglycoprotein2 3     Scavenger Receptor Class B Member 23

External Ids:    HGNC: 16651   Entrez Gene: 9502   Ensembl: ENSG000001387607   OMIM: 6022575   UniProtKB: Q141083   

Export aliases for SCARB2 gene to outside databases

Previous GC identifers: GC04M076978 GC04M077272 GC04M077472 GC04M077540 GC04M077538 GC04M077437 GC04M077298 GC04M072831


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SCARB2:
The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of
lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane
transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported
to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral
neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is
involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by
coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also
known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different
isoforms have been found for this gene.(provided by RefSeq, Feb 2011)

UniProtKB/Swiss-Prot: SCRB2_HUMAN, Q14108
Function: Acts as a lysosomal receptor for glucosylceramidase (GBA) targeting

Gene Wiki entry for SCARB2


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.1  NT_016354.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SCARB2 gene promoter:
         NF-1   AP-2alpha isoform 3   AP-1   ATF-2   AP-2alpha isoform 2   PPAR-gamma1   AP-2alpha isoform 4   c-Jun   PPAR-gamma2   AP-2alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSCARB2 promoter sequence
   Search SABiosciences Chromatin IP Primers for SCARB2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SCARB2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q21.1   Ensembl cytogenetic band:  4q21.1   HGNC cytogenetic band: 4q21.1

SCARB2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SCARB2 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M077079:  view genomic region     (about GC identifiers)

Start:
77,079,890 bp from pter      End:
77,135,046 bp from pter
Size:
55,157 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: SCRB2_HUMAN, Q14108 (See protein sequence)
Recommended Name: Lysosome membrane protein 2  
Size: 478 amino acids; 54290 Da
Subunit: Interacts with GBA (via the coiled-coil domain)
Subcellular location: Lysosome membrane; Multi-pass membrane protein
Mass spectrometry: Mass=54158.97; Method=MALDI; Range=2-478; Source=PubMed:11840567;
Secondary accessions: B4DKD8 E7EM68 Q53Y63
Alternative splicing: 2 isoforms:  Q14108-1   Q14108-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SCARB2: NX_Q14108

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q14108

  • SCARB2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001191184.1  NP_005497.1  

    ENSEMBL proteins: 
     ENSP00000264896   ENSP00000399154   ENSP00000420988  

    Human Recombinant Protein Products: 
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    Uscn Proteins for SCARB2

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005624membrane fraction ----
    GO:0005764lysosome ----
    GO:0005765lysosomal membrane ISS18022370
    GO:0005887integral to plasma membrane TAS1374238
    GO:0016020membrane TAS1374238


    SCARB2 for ontologies           About GeneDecksing



    SCARB2 Antibody Products: 
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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    SCARB2 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR005429 LimpII
     IPR002159 CD36

    Graphical View of Domain Structure for InterPro Entry Q14108

    ProtoNet protein and cluster: Q14108

    2 Blocks protein families:
    IPB002159 Adhesion molecule CD36 family signature
    IPB005429 Lysosome membrane protein II (LIMP II) signature


    UniProtKB/Swiss-Prot: SCRB2_HUMAN, Q14108
    Similarity: Belongs to the CD36 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: SCRB2_HUMAN, Q14108
    Function: Acts as a lysosomal receptor for glucosylceramidase (GBA) targeting

    miRNA
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    hsa-miR-300 hsa-miR-513a-5p hsa-miR-548k hsa-miR-1245 hsa-miR-200a hsa-miR-4305 hsa-miR-219-5p hsa-miR-508-3p
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004872receptor activity IEA--
    GO:0019899enzyme binding IPI18022370


    SCARB2 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-out Scarb2tm1Psa for SCARB2
         8 MGI mutant phenotypes (inferred from 1 allele(MGI details for Scarb2):
     behavior/neurological  cardiovascular system  growth/size  hearing/vestibular/ear  homeostasis/metabolism 
     mortality/aging  nervous system  renal/urinary system 

    SCARB2 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Lysosome
    Lysosome1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways



    1         Kegg Pathway  (Kegg details for SCARB2):
        Lysosome


    SCARB2 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SCARB2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    5/43 Interacting proteins for SCARB2 (Q141081, 2, 3 ENSP000002648964) via UniProtKB, MINT, STRING, and/or I2D (see all 43)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PLCG1P191742, 3, ENSP000002440074MINT-7309951 MINT-7309916 I2D: score=1 STRING: ENSP00000244007
    CAV1Q031352, 3, ENSP000003391914MINT-7309906 I2D: score=1 STRING: ENSP00000339191
    CSKP412402, 3, ENSP000002200034MINT-7309937 I2D: score=1 STRING: ENSP00000220003
    GBAP040622, 3, ENSP000003145084MINT-4054731 I2D: score=1 STRING: ENSP00000314508
    AP3S1Q925723, ENSP000003253694I2D: score=2 STRING: ENSP00000325369
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006622protein targeting to lysosome IMP18022370
    GO:0007155cell adhesion IEA--


    SCARB2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SCARB2 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SCARB2
    9 Novoseek chemical compound relationships for SCARB2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    u18666a 67.3 1 14733906 (1)
    phosphoramidon 57.6 1 8615890 (1)
    leucine 31.7 6 12370188 (2), 10985965 (1)
    cholesterol 30.8 10 14570588 (5), 9614139 (2), 12356916 (1), 15114099 (1) (see all 5)
    zinc 17.9 2 10620363 (1), 9177475 (1)
    lipid 9.55 3 9614139 (2), 17967141 (1)
    tacrolimus 2.8 1 15114099 (1)
    alanine 0 1 10753663 (1)
    polysaccharide 0 1 1560026 (1)

    Search CenterWatch for drugs/clinical trials and news about SCARB2 / SCRB2 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SCARB2 gene (2 alternative transcripts): 
    NM_001204255.1  NM_005506.3  

    Unigene Cluster for SCARB2:

    Scavenger receptor class B, member 2
    Hs.349656  [show with all ESTs]
    Unigene Representative Sequence: NM_005506
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000264896(uc003hju.2 uc011cbu.2) ENST00000452464 ENST00000511129
    ENST00000502908 ENST00000509994

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    hsa-miR-300 hsa-miR-513a-5p hsa-miR-548k hsa-miR-1245 hsa-miR-200a hsa-miR-4305 hsa-miR-219-5p hsa-miR-508-3p
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    Additional cDNA sequence: 

    AK056001.1 AK296519.1 AK313016.1 BC021892.1 BC035111.1 BT006939.1 D12676.1 

    20 DOTS entries:

    DT.100686283  DT.456246  DT.100886539  DT.100886545  DT.121235180  DT.100046105  DT.95069189  DT.121235207 
    DT.100886544  DT.100886555  DT.121235213  DT.100716407  DT.121235228  DT.99971108  DT.121235206  DT.121235208 
    DT.92442764  DT.95136807  DT.95159015  DT.40217279 

    24/571 AceView cDNA sequences (see all 571):

    BT006939 BG109877 AA479214 AA361420 AI096722 CA840901 BE552003 BM760331 
    CA434973 AI597644 BM679492 AI282749 AI816733 AI004146 BM823672 CA840905 
    AA576723 AA056647 CA390492 CA841153 AA877238 CA417917 CB851965 BQ575359 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for SCARB2    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b · 13c
    SP1:                          -           -                                                                     
    SP2:                                                                                                            
    SP3:                                                                                            -               
    SP4:                          -                                                                                 


    ECgene alternative splicing isoforms for SCARB2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SCARB2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTTATTTCTA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See SCARB2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SCARB2

    SOURCE GeneReport for Unigene cluster: Hs.349656
        SABiosciences Custom PCR Arrays for SCARB2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCARB2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SCARB2 gene from 6/20 species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Scarb21 , 5 scavenger receptor class B, member 21, 5 84.52(n)1
    85.77(a)1
      5 (46.82 cM)5
    124921  NM_007644.31  NP_031670.11 
     924438735 
    chicken
    (Gallus gallus)
    Aves SCARB21 scavenger receptor class B, member 2 65.9(n)
    59.62(a)
      422638  XM_420593.3  XP_420593.1 
    lizard
    (Anolis carolinensis)
    Reptilia SCARB26
    --
    53(a)
    1 ↔ 1
    5(146878187-146906456)
    African clawed frog
    (Xenopus laevis)
    Amphibia cd36l2-prov2 CD36 antigen (collagen type I receptor, thrombospondin more 74.15(n)    BC045028.1 
    zebrafish
    (Danio rerio)
    Actinopterygii cd36l22 CD36 antigen (collagen type I receptor, thrombospondin more 75.09(n)   192340  AY099528.1 
    worm
    (Caenorhabditis elegans)
    Secernentea scav-36
    scav-26
    (see all 6)
    --
    24(a)
    23(a)
    (see all 6)
    possible ortholog
    possible ortholog
    (see all 6)
    III(12453487-12456751)
    III(13551081-13555233)


    ENSEMBL Gene Tree for SCARB2 (if available)
    TreeFam Gene Tree for SCARB2 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SCARB2 gene
    SCARB12  CD362  
    2 SIMAP similar genes for SCARB2 using alignment to 3 protein entries:     SCRB2_HUMAN (see all proteins):
    SCARB1    CD36

    SCARB2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for SCARB2
         1 CNV: 10049
    Human Gene Mutation Database (HGMD): SCARB2
    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    SCARB2 for disorders           About GeneDecksing

    OMIM gene information: 602257   
    OMIM disorders: 254900  
    UniProtKB/Swiss-Prot: SCRB2_HUMAN, Q14108
  • Defects in SCARB2 are the cause of progressive myoclonic epilepsy type 4 with or without renal failure (EPM4)
  • [MIM:254900]. An autosomal recessive progressive myoclonic epilepsy associated with renal failure in some cases.
    Cognitive function is preserved. Myoclonus is a brief, involuntary twitching of a muscle or a group of muscles.
    Cognitive function is preserved
  • Note=Genetic variants in SCARB2 can act as modifier of the phenotypic expression and severity of Gaucher
  • disease

    20/30 diseases for SCARB2 (see all 30):    About MalaCards
    action myoclonus-renal failure syndrome    hand, foot and mouth disease    mouth disease    myoclonus
    peripheral neuropathy    neuropathy    myoclonus epilepsy    progressive myoclonus epilepsy
    protein s deficiency    acute lymphoblastic leukemia    lymphoblastic leukemia    gaucher's disease
    nephrotic syndrome    glomerulosclerosis    hepatitis c    hepatitis b
    parkinson's disease    choriocarcinoma    choroiditis    dementia

    3 diseases from the University of Copenhagen DISEASES database for SCARB2:
    Malaria     Atherosclerosis     Diabetes mellitus

    2 Novoseek disease relationships for SCARB2 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    necrosis 0 3 7500022 (1), 10533808 (1), 10614784 (1)
    tumors 0 4 7500022 (1), 10533808 (1), 10614784 (1), 11095979 (1)

    Human Genome Epidemiology (HuGE) Navigator: SCARB2 (6 documents)

    Export disorders for SCARB2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SCARB2 gene, integrated from 9 sources (see all 151):
    (articles sorted by number of sources associating them with SCARB2)
        Utopia: connect your pdf to the dynamic
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    1. Isolation and sequencing of a cDNA clone encoding the 85 kDa human lysosomal sialoglycoprotein (hLGP85) in human metastatic pancreas islet tumor cells. (PubMed id 1374238)1, 2, 3, 9 Fujita H....Kato K. (1992)
    2. The CD36, CLA-1 (CD36L1), and LIMPII (CD36L2) gene family: cellular distribution, chromosomal location, and genetic evolution. (PubMed id 7539776)1, 2, 9 Calvo D.... Vega M.A. (1995)
    3. The residues Leu(Ile)475-Ile(Leu, Val, Ala)476, contained in the extended carboxyl cytoplasmic tail, are critical for targeting of the resident lysosomal membrane protein LIMP II to lysosomes. (PubMed id 7509809)1, 2, 9 Sandoval I.V.... Rico M. (1994)
    4. A mutation in SCARB2 is a modifier in Gaucher disease. (PubMed id 21796727)1, 2 Velayati A....Sidransky E. (2011)
    5. Array-based gene discovery with three unrelated subjects shows SCARB2/LIMP-2 deficiency causes myoclonus epilepsy and glomerulosclerosis. (PubMed id 18308289)1, 2 Berkovic S.F.... Bahlo M. (2008)
    6. LIMP-2 is a receptor for lysosomal mannose-6-phosphate-independent targeting of beta-glucocerebrosidase. (PubMed id 18022370)1, 2 Reczek D....Saftig P. (2007)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    9. Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry. (PubMed id 12754519)1, 2 Zhang H.... Aebersold R. (2003)
    10. Cluster analysis of an extensive human breast cancer cell line protein expression map database. (PubMed id 11840567)1, 2 Harris R.A....Zvelebil M.J. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 950 HGNC: 1665 AceView: SCARB2 Ensembl:ENSG00000138760 euGenes: HUgn950
    ECgene: SCARB2 Kegg: 950 H-InvDB: SCARB2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SCARB2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SCARB2 gene:
    Search GeneIP for patents involving SCARB2

    GeneCards and IP:
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