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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SCAMP5 Gene

protein-coding   GIFtS: 49
GCID: GC15P075287

secretory carrier membrane protein 5
 Explore 2 diseases affiliated with
SCAMP5 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SCAMP5    

Aliases
for SCAMP5 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Secretory Carrier Membrane Protein 51 2 3
HSCAMP51
MGC249691
Secretory Carrier-Associated Membrane Protein 52

External Ids:    HGNC: 303861   Entrez Gene: 1926832   Ensembl: ENSG000001987947   OMIM: 6137665   UniProtKB: Q8TAC93   

Export aliases for SCAMP5 gene to outside databases

Previous GC identifers: GC15P071137 GC15P068402 GC15P072863 GC15P073003 GC15P073074 GC15P052084


Summaries
for SCAMP5 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: SCAM5_HUMAN, Q8TAC9
Function: Required for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5. Probably
acts in cooperation with the SNARE machinery. May play a role in accumulation of expanded polyglutamine (polyQ)
protein huntingtin (HTT) in case of endoplasmic reticulum stress by inhibiting the endocytosis pathway

Gene Wiki entry for SCAMP5


Genomic Views
for SCAMP5 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NC_018926.1  NT_010194.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SCAMP5 gene promoter:
         SRF   C/EBPbeta   AML1a   SRF (504 AA)   p300   NRSF form 1   NRSF form 2   Egr-4   PPAR-gamma1   HSF2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SCAMP5 promoter sequence
   Search SABiosciences Chromatin IP Primers for SCAMP5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SCAMP5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q24.2   Ensembl cytogenetic band:  15q24.2   HGNC cytogenetic band: 15q23

SCAMP5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SCAMP5 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P075287:  view genomic region     (about GC identifiers)

Start:
 75,249,560 bp from pter      End:
 75,313,837 bp from pter
Size:
 64,278 bases      Orientation:
 plus strand

Proteins
for SCAMP5 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: SCAM5_HUMAN, Q8TAC9 (See protein sequence)
Recommended Name: Secretory carrier-associated membrane protein 5  
Size: 235 amino acids; 26104 Da
Subunit: Interacts (via C-terminal part) with SYT1 and SYT2; interaction with synaptotagmins making a link with the
SNARE molecules. Interacts with SLC9A7
Subcellular location: Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane
protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Recycling endosome membrane;
Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane
protein (By similarity). Note=Mainly localizes in Golgi apparatus membrane. Upon calcium-triggered exocytosis, it
translocates to the cell membrane. Highly enriched in synaptic vesicles (By similarity)
Secondary accessions: B3KPJ7 B7Z762 D3DW71 Q8N3M4
Alternative splicing: 3 isoforms:  Q8TAC9-1   Q8TAC9-2   Q8TAC9-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SCAMP5: NX_Q8TAC9

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8TAC9

    • SCAMP5 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_001171582.1  NP_001171583.1  NP_620417.1  

    ENSEMBL proteins: 
     ENSP00000457520   ENSP00000406547   ENSP00000456505   ENSP00000456991   ENSP00000455313  
     ENSP00000454860   ENSP00000455598   ENSP00000454766   ENSP00000458072   ENSP00000355387  
     ENSP00000457444   ENSP00000457121   ENSP00000455039   ENSP00000455203   ENSP00000454602  
     ENSP00000439685  

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    Uscn Proteins for SCAMP5

    Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IDA19234194
    GO:0005886plasma membrane IDA19234194
    GO:0016021integral to membrane IDA19234194
    GO:0030054cell junction IEA--
    GO:0030672synaptic vesicle membrane IEA--


    SCAMP5 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for SCAMP5 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SCAMP5 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR007273 SCAMP

    Graphical View of Domain Structure for InterPro Entry Q8TAC9

    ProtoNet protein and cluster: Q8TAC9

    UniProtKB/Swiss-Prot: SCAM5_HUMAN, Q8TAC9
    Similarity: Belongs to the SCAMP family. SCAMP5 subfamily


    Function
    for SCAMP5 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: SCAM5_HUMAN, Q8TAC9
    Function: Required for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5. Probably
    acts in cooperation with the SNARE machinery. May play a role in accumulation of expanded polyglutamine (polyQ)
    protein huntingtin (HTT) in case of endoplasmic reticulum stress by inhibiting the endocytosis pathway
    Induction: By endoplasmic reticulum stress

    miRNA
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    8/60 QIAGEN miScript miRNA Assays for microRNAs that regulate SCAMP5 (see all 60):
    hsa-miR-4254 hsa-miR-631 hsa-miR-106a hsa-miR-765 hsa-miR-29a hsa-let-7a-2* hsa-miR-138-2* hsa-miR-519a
    SwitchGear 3'UTR luciferase reporter plasmid: SCAMP5 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    Search LifeMap BioReagents cell lines for SCAMP5

    In Situ Assay
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI19234194


    SCAMP5 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for SCAMP5:
     Actin fiber cells 


    Pathways & Interactions
    for SCAMP5 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SCAMP5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/10 Interacting proteins for SCAMP5 (Q8TAC91, 3 ENSP000004065474) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SLC9A7Q96T833, ENSP000003303204I2D: score=1 STRING: ENSP00000330320
    STX4Q128463, ENSP000003177144I2D: score=1 STRING: ENSP00000317714
    STX8Q9UNK03, ENSP000003052554I2D: score=1 STRING: ENSP00000305255
    VAMP3Q158363, ENSP000000546664I2D: score=1 STRING: ENSP00000054666
    SNAP23O001613, ENSP000002496474I2D: score=1 STRING: ENSP00000249647
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006887exocytosis IEA--
    GO:0015031protein transport IEA--
    GO:0034976response to endoplasmic reticulum stress IDA19240033
    GO:0045806negative regulation of endocytosis IDA19240033
    GO:0045956positive regulation of calcium ion-dependent exocytosis IDA19234194


    SCAMP5 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SCAMP5 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SCAMP5
    Search CenterWatch for drugs/clinical trials and news about SCAMP5 / SCAM5 

    Transcripts
    for SCAMP5 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SCAMP5 gene (3 alternative transcripts): 
    NM_001178111.1  NM_001178112.1  NM_138967.3  

    Unigene Cluster for SCAMP5:

    Secretory carrier membrane protein 5
    Hs.374180  [show with all ESTs]
    Unigene Representative Sequence: AL390185
    18/19 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19):
    ENST00000568423 ENST00000425597(uc002azm.2 uc002azk.2 uc010uly.2 uc002azn.2)
    ENST00000562327 ENST00000568018 ENST00000562212 ENST00000565923 ENST00000567920
    ENST00000562765 ENST00000567535 ENST00000566872 ENST00000564491 ENST00000361900(uc002azl.2)
    ENST00000564141 ENST00000568119 ENST00000565989 ENST00000564779 ENST00000567529
    ENST00000568081

    miRNA
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    8/60 QIAGEN miScript miRNA Assays for microRNAs that regulate SCAMP5 (see all 60):
    hsa-miR-4254 hsa-miR-631 hsa-miR-106a hsa-miR-765 hsa-miR-29a hsa-let-7a-2* hsa-miR-138-2* hsa-miR-519a
    SwitchGear 3'UTR luciferase reporter plasmid: SCAMP5 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SCAMP5 (see all 7)
    OriGene shRNA RFP: SCAMP5
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    Clone
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    Primer
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    Additional cDNA sequence: 

    AF495715.1 AK025678.1 AK056438.1 AK126940.1 AK127480.1 AK301505.1 AL360203.1 AL390185.1 
    AL833230.1 AL834226.1 BC024700.1 BC141942.1 BC141943.1 BC150506.1 BC150507.1 CR936761.1 
    NR_033660.1 

    15 DOTS entries:

    DT.97854060  DT.101983913  DT.115460  DT.121055831  DT.100029689  DT.100823119  DT.100823122  DT.100673164 
    DT.121055779  DT.121055763  DT.97762427  DT.100773044  DT.91852797  DT.91939244  DT.100784701 

    24/169 AceView cDNA sequences (see all 169):

    AA350399 AA928538 Z40103 AI272341 BM821292 AF495715 AA339566 AL360203 
    BM672960 BQ643781 H84247 AA663609 BU732702 NM_138967 BC024700 BI259921 
    AI424678 BM926986 AL390185 AK056438 BM710582 T32900 AK126940 BQ647211 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for SCAMP5 (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b
    SP1:              -     -                       -                                       
    SP2:              -           -                 -                                       
    SP3:              -     -     -                 -                                       
    SP4:              -     -     -                 -     -     -                           
    SP5:                    -     -                 -                                       


    ECgene alternative splicing isoforms for SCAMP5

    Expression
    for SCAMP5 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SCAMP5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CTCTGGCTCT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See SCAMP5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SCAMP5

    SOURCE GeneReport for Unigene cluster: Hs.374180

    UniProtKB/Swiss-Prot: SCAM5_HUMAN, Q8TAC9
    Tissue specificity: Expressed both by neuronal and non-neuronal tissues. Expressed in brain, stomach, thyroid, spinal
    cord, lymph node, trachea, adrenal gland, bone marrow and in the different parts of brain. In thyroid tissues, it is
    expressed by the follicular epithelial cells. In the adrenal gland tissues it is detected in the zona fasciculata of
    the cortex region (at protein level)

        SABiosciences Custom PCR Arrays for SCAMP5
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    In Situ
    Assay Products:     
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    Orthologs
    for SCAMP5 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SCAMP5 gene from 8/21 species (see all 21)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves SCAMP51 secretory carrier membrane protein 5 83.69(n)
    91.49(a)    		   426413  XM_424061.3  XP_424061.2 
    lizard
    (Anolis carolinensis)    		 Reptilia SCAMP56
    		 --
    		 86(a)
    		 1 ↔ 1
    		 GL343492.1(500413-505941)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia Str.23182 Transcribed sequence with weak similarity to protein more 77.47(n)    CF221817.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii scamp51 secretory carrier membrane protein 5 75.65(n)
    82.17(a)    		   324467  NM_205547.1  NP_991110.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Scamp6
    		 Scamp
    		 28(a)
    		 1 → many
    		 X(15340212-15343916)
    worm
    (Caenorhabditis elegans)    		 Secernentea scm-16
    		 SCAMP (synaptic vesicle protein) homolog family me...
    		 27(a)
    		 1 → many
    		 I(1862614-1872308)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT2G208406
    SC36
    (see all 5)    		 secretory carrier-associated membrane protein 3
    (see all 5)    		 19(a)
    18(a)
    (see all 5)    		 many ↔ many
    many ↔ many
    (see all 5)    		 2(8971712-8974485)
    1(22585838-22588969)
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    (see all 8)    		 secretory carrier-associated membrane protein 5, p...
    secretory carrier-associated membrane protein, put...
    (see all 8)    		 20(a)
    17(a)
    (see all 8)    		 many ↔ many
    many ↔ many
    (see all 8)    		 8(3615627-3617822)
    4(29924842-29928534)


    ENSEMBL Gene Tree for SCAMP5 (if available)
    TreeFam Gene Tree for SCAMP5 (if available) 

    Paralogs
    for SCAMP5 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SCAMP5 gene
    SCAMP32  SCAMP22  SCAMP42  
    4 SIMAP similar genes for SCAMP5 using alignment to 10 protein entries:     SCAM5_HUMAN (see all proteins):
    SCAMP2    SCAMP4    SCAMP1    SCAMP3

    SCAMP5 for paralogs           About GeneDecksing



    Genomic Variants
    for SCAMP5 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/478 NCBI SNPs in SCAMP5 are shown (see all 478)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 15 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1930939521,2
    		--75285939(+) ACCATA/CCTTAT 4 -- us2k10--------
    rs587641591,2
    		C,F,--75286092(+) TGCCTA/CTTAAG 4 -- us2k11Minor allele frequency- C:0.02WA 118
    rs1178123181,2
    		--75286106(+) ACGTTT/GGTTTA 4 -- us2k11Minor allele frequency- G:0.01NA 120
    rs788193881,2
    		C,F,--75286130(+) CCCTTC/TCATTT 4 -- us2k11Minor allele frequency- T:0.02NA 120
    rs580688871,2
    		C,F,--75286140(+) TACCTG/AAATAG 4 -- us2k16Minor allele frequency- A:0.31WA CSA NA EA 364
    rs1121275981,2
    		--75286280(+) TCAGAT/CGGGAA 4 -- us2k11Minor allele frequency- C:0.00CSA 1
    rs594236131,2
    		C,F,--75286281(+) CAGACG/AGGAAC 4 -- us2k15Minor allele frequency- A:0.26WA CSA 125
    rs1445609651,2
    		--75286291(+) CCCCAA/GTATTT 4 -- us2k10--------
    rs1858006351,2
    		--75286318(+) ATGAAA/CCACAA 4 -- us2k10--------
    rs1883256111,2
    		--75286335(+) TCCTAC/TAAATT 4 -- us2k10--------

    HapMap Linkage Disequilibrium report for SCAMP5 (75249560 - 75313837 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for SCAMP5
         1 Inversion: 37170

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    Disorders / Diseases
    for SCAMP5 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SCAMP5 for disorders           About GeneDecksing

    OMIM gene information: 613766    OMIM disorders: --

    2 diseases for SCAMP5:    About MalaCards
    thyroiditis    neuronitis


    Export disorders for SCAMP5 gene to outside databases

    Publications
    for SCAMP5 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SCAMP5 gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with SCAMP5)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. SCAMP5 links ER stress to the accumulation of expanded polyglutamine protein aggregates via endocytosis inhibition. (PubMed id 19240033)1, 2 Noh J.-Y....Jung Y.-K. (2009)
    2. Human SCAMP5, a novel secretory carrier membrane protein, facilitates calcium-triggered cytokine secretion by interaction with SNARE machinery. (PubMed id 19234194)1, 2 Han C.... Cao X. (2009)
    3. Secretory carrier membrane proteins interact and regulate trafficking of the organellar (Na+,K+)/H+ exchanger NHE7. (PubMed id 15840657)1, 2 Lin P.J.... Numata M. (2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    7. Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption. (PubMed id 21490707)1 Cornelis M.C....Caporaso N.E. (2011)
    8. Interactome mapping suggests new mechanistic details u nderlying Alzheimer's disease. (PubMed id 21163940)1 Soler-Lopez M....Aloy P. (2011)
    9. SCAMP5, NBEA and AMISYN: three candidate genes for au tism involved in secretion of large dense-core vesicles. (PubMed id 20071347)1 Castermans D....Creemers J.W. (2010)
    10. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)

    External Searches for SCAMP5 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing SCAMP5 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 192683 HGNC: 30386 AceView: SCAMP5 Ensembl:ENSG00000198794 euGenes: HUgn192683
    ECgene: SCAMP5 H-InvDB: SCAMP5

    Other Databases showing SCAMP5 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SCAMP5 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SCAMP5 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SCAMP5 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SCAMP5 gene:
    Search GeneIP for patents involving SCAMP5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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