Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



SCAMP4 Gene

protein-coding   GIFtS: 47
GCID: GC19P001905

Secretory Carrier Membrane Protein 4

  Search for SCAMP4
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Secretory Carrier Membrane Protein 41 2 3
SCAMP-42
Secretory Carrier-Associated Membrane Protein 42

External Ids:    HGNC: 303851   Entrez Gene: 1131782   Ensembl: ENSG000002275007   OMIM: 6137645   UniProtKB: Q969E23   

Export aliases for SCAMP4 gene to outside databases

Previous GC identifers: GC19P001859 GC19P001860 GC19P001862 GC19P001676


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for SCAMP4 Gene:
Secretory carrier membrane proteins (SCAMPs) are widely distributed integral membrane proteins implicated in
membrane trafficking. Most SCAMPs (e.g., SCAMP1; MIM 606911) have N-terminal cytoplasmic NPF (arg-pro-phe)
repeats, 4 central transmembrane regions, and a short C-terminal cytoplasmic tail. These SCAMPs likely have a
role in endocytosis that is mediated by their NPF repeats. Other SCAMPs, such as SCAMP4, lack the NPF repeats and
are therefore unlikely to function in endocytosis (summary by Fernandez-Chacon and Sudhof, 2000 (PubMed
11050114)).(supplied by OMIM, Feb 2011)

GeneCards Summary for SCAMP4 Gene:
SCAMP4 (secretory carrier membrane protein 4) is a protein-coding gene. An important paralog of this gene is SCAMP3.

UniProtKB/Swiss-Prot: SCAM4_HUMAN, Q969E2
Function: Probably involved in membrane protein trafficking (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000019.10  NC_018930.2  NT_011295.12  
Regulatory elements:
   Regulatory transcription factor binding sites in the SCAMP4 gene promoter:
         Max1   Pax-5   Tal-1   Olf-1   E47   Max   ZID   c-Myc   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): SCAMP4 promoter sequence
   Search Chromatin IP Primers for SCAMP4

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SCAMP4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.3   Ensembl cytogenetic band:  19p13.3   HGNC cytogenetic band: 19p13.3

SCAMP4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SCAMP4 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P001905:  view genomic region     (about GC identifiers)

Start:
1,905,213 bp from pter      End:
1,926,016 bp from pter
Size:
20,804 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: SCAM4_HUMAN, Q969E2 (See protein sequence)
Recommended Name: Secretory carrier-associated membrane protein 4  
Size: 229 amino acids; 25728 Da
Secondary accessions: Q8N2N1 Q8NAV0
Alternative splicing: 3 isoforms:  Q969E2-1   Q969E2-2   Q969E2-3   

Explore the universe of human proteins at neXtProt for SCAMP4: NX_Q969E2

Explore proteomics data for SCAMP4 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys4, Lys185
  • Modification sites at PhosphoSitePlus

  • See SCAMP4 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_524558.1  
    ENSEMBL proteins: 
     ENSP00000316007   ENSP00000386865   ENSP00000388185   ENSP00000465199  

    SCAMP4 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for SCAMP4
    OriGene Custom MassSpec
    OriGene Custom Protein Services for SCAMP4
    GenScript Custom Purified and Recombinant Proteins Services for SCAMP4
    Novus Biologicals SCAMP4 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SCAMP4

    SCAMP4 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for SCAMP4
    OriGene Custom Antibody Services for SCAMP4
    Novus Biologicals SCAMP4 Antibody
    Abcam antibodies for SCAMP4
    Cloud-Clone Corp. Antibodies for SCAMP4
    ThermoFisher Antibodies for SCAMP4
    LSBio Antibodies in human, mouse, rat for SCAMP4

    SCAMP4 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for SCAMP4
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SCAMP4
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SCAMP4
    Cloud-Clone Corp. CLIAs for SCAMP4


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    SCAMP: Secretory carrier membrane proteins

    1 InterPro protein domain:
     IPR007273 SCAMP

    Graphical View of Domain Structure for InterPro Entry Q969E2

    ProtoNet protein and cluster: Q969E2

    UniProtKB/Swiss-Prot: SCAM4_HUMAN, Q969E2
    Similarity: Belongs to the SCAMP family


    SCAMP4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SCAM4_HUMAN, Q969E2
    Function: Probably involved in membrane protein trafficking (By similarity)

    Animal Models:

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SCAMP4
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SCAMP4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SCAMP4
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SCAMP4

    miRNA
    Products:
        
    miRTarBase miRNAs that target SCAMP4:
    hsa-mir-193b-3p (MIRT041297), hsa-mir-1226-3p (MIRT036439)

    Block miRNA regulation of human, mouse, rat SCAMP4 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate SCAMP4:
    hsa-miR-495 hsa-miR-298 hsa-miR-7-2* hsa-miR-7-1* hsa-miR-143
    SwitchGear 3'UTR luciferase reporter plasmidSCAMP4 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SCAMP4
    Predesigned siRNA for gene silencing in human, mouse, rat SCAMP4

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SCAMP4

    Clone
    Products:
         
    OriGene clones in human, mouse for SCAMP4 (see all 10)
    OriGene ORF clones in mouse, rat for SCAMP4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SCAMP4 (NM_079834)
    Sino Biological Human cDNA Clone for SCAMP4
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SCAMP4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCAMP4

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for SCAMP4
    Browse ESI BIO Cell Lines and PureStem Progenitors for SCAMP4 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCAMP4


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    SCAM4_HUMAN, Q969E2: Membrane; Multi-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    golgi apparatus1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    SCAMP4 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus




        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SCAMP4
    Interactions:

        Search GeneGlobe Interaction Network for SCAMP4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    Selected Interacting proteins for SCAMP4 (ENSP000003160074) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCENSP000003448184STRING: ENSP00000344818
    JAGN1ENSP000003061064STRING: ENSP00000306106
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    RAB4AENSP000003556514STRING: ENSP00000355651
    RAB4BENSP000003495604STRING: ENSP00000349560
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015031protein transport IEA--

    SCAMP4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SCAMP4 (SCAM4)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for SCAMP4 gene: 
    NM_079834.2  

    Unigene Cluster for SCAMP4:

    Secretory carrier membrane protein 4
    Hs.144980  [show with all ESTs]
    Unigene Representative Sequence: BC062598
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000316097(uc002luj.3 uc002luk.3 uc010dss.3) ENST00000452128(uc002lui.1)
    ENST00000414057 ENST00000460767 ENST00000489554 ENST00000588555 ENST00000409472
    ENST00000411971 ENST00000588907 ENST00000590266 ENST00000585335 ENST00000472442

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SCAMP4 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate SCAMP4:
    hsa-miR-495 hsa-miR-298 hsa-miR-7-2* hsa-miR-7-1* hsa-miR-143
    SwitchGear 3'UTR luciferase reporter plasmidSCAMP4 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SCAMP4
    Predesigned siRNA for gene silencing in human, mouse, rat SCAMP4
    Clone
    Products:
         
    OriGene clones in human, mouse for SCAMP4 (see all 10)
    OriGene ORF clones in mouse, rat for SCAMP4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SCAMP4 (NM_079834)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SCAMP4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCAMP4
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for SCAMP4
    OriGene qSTAR qPCR primer pairs in human, mouse for SCAMP4
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SCAMP4
      QuantiTect SYBR Green Assays in human, mouse, rat SCAMP4
      QuantiFast Probe-based Assays in human, mouse, rat SCAMP4

    Additional mRNA sequence: 

    AF109187.1 AF173896.1 AK074967.1 AK092056.1 AK126544.1 AK307641.1 AK307700.1 AL832731.1 
    BC007958.2 BC011747.2 BC011824.1 BC016509.1 BC016685.1 BC062598.1 BX647235.1 

    17 DOTS entries:

    DT.315460  DT.121428532  DT.91725809  DT.100802577  DT.40314413  DT.121428533  DT.100781213  DT.91749470 
    DT.99942447  DT.121428529  DT.100781214  DT.121428537  DT.121428554  DT.97812873  DT.121428543  DT.121428546 
    DT.40195006 

    Selected AceView cDNA sequences (see all 362):

    BP355986 BU542053 BM714166 CR610772 AK096105 BM691899 BE207068 BI761802 
    BU626013 BM708430 AI017809 BM713797 BU844505 BU541426 BM044653 AA232686 
    BC011824 NM_138422 AI208430 BX105110 BM694499 AI470071 CR607576 BU543140 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    SCAMP4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTTCTGCACT
    SCAMP4 Expression
    About this image

    SCAMP4 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SCAMP4 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.144980
        Custom PCR Arrays for SCAMP4
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for SCAMP4
    OriGene qSTAR qPCR primer pairs in human, mouse for SCAMP4
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SCAMP4
    QuantiTect SYBR Green Assays in human, mouse, rat SCAMP4
    QuantiFast Probe-based Assays in human, mouse, rat SCAMP4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCAMP4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for SCAMP4 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Scamp41 , 5 secretory carrier membrane protein 41, 5 82.82(n)1
    83.84(a)1
      10 (39.72 cM)5
    562141  NM_019575.41  NP_062521.11 
     806028825 
    chicken
    (Gallus gallus)
    Aves SCAMP41 secretory carrier membrane protein 4 75.84(n)
    75.55(a)
      420081  XM_004948767.1  XP_004948824.1 
    zebrafish
    (Danio rerio)
    Actinopterygii scamp41 secretory carrier membrane protein 4 61.26(n)
    60.96(a)
      562881  NM_001025525.1  NP_001020696.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Scamp6
    Scamp
    29(a)
    1 → many
    X(15340212-15343916)
    worm
    (Caenorhabditis elegans)
    Secernentea scm-16
    Protein SCM-1 (scm-1) mRNA, complete cds
    27(a)
    1 → many
    I(1862612-1872306) WBGene00004743


    ENSEMBL Gene Tree for SCAMP4 (if available)
    TreeFam Gene Tree for SCAMP4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for SCAMP4 gene
    SCAMP32  SCAMP22  SCAMP52  SCAMP12  
    4 SIMAP similar genes for SCAMP4 using alignment to 3 protein entries:     SCAM4_HUMAN (see all proteins):
    SCAMP2    SCAMP5    SCAMP3    SCAMP1

    SCAMP4 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for SCAMP4 (see all 430)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1380188641,2
    C--1913970(+) CCACT-/GGCTGG 1 -- int10--------
    rs621277371,2
    F--1913994(+) AGGCCC/TGCAGT 1 -- int11Minor allele frequency- T:0.50NA 2
    rs16101041,2
    C,F,H--1914048(+) GTCCCT/GGATGG 1 -- int113Minor allele frequency- G:0.13NA WA CSA EA 376
    rs739168231,2
    C,F--1914146(+) TGCTCA/GGGTGC 1 -- int12Minor allele frequency- G:0.14WA 120
    rs1421885571,2
    --1914267(+) CCCCAC/TGGTGA 1 -- int10--------
    rs599884991,2
    C,F--1914363(+) CCGTGC/TCCGCC 1 -- int11Minor allele frequency- T:0.50WA 2
    rs1389668911,2
    --1914376(+) CTCGGA/GCCTGT 1 -- int10--------
    rs1853671421,2
    --1914431(+) ATGCCC/TAGTGG 1 -- int10--------
    rs1428858831,2
    --1914441(+) GGCAGC/TAGGCA 1 -- int10--------
    rs562123561,2
    C,F--1914465(+) CTGGCT/CCACCT 1 -- int18Minor allele frequency- C:0.47NA CSA WA EA 367

    HapMap Linkage Disequilibrium report for SCAMP4 (1905213 - 1926016 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for SCAMP4 (see all 24):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2717855CNV Deletion23290073
    esv2717854CNV Deletion23290073
    esv2675682CNV Deletion23128226
    esv2717853CNV Deletion23290073
    esv2571215CNV Insertion19546169
    nsv470107CNV Loss18288195
    dgv3614n71CNV Loss21882294
    nsv910499CNV Loss21882294
    nsv910588CNV Loss21882294
    dgv3609n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SCAMP4
    DNA2.0 Custom Variant and Variant Library Synthesis for SCAMP4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 613764    OMIM disorders: --


    SCAMP4 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SCAMP4
    Human Genome Epidemiology (HuGE) Navigator: SCAMP4 (1 document)

    Export disorders for SCAMP4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for SCAMP4 gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with SCAMP4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    5. Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (J. Proteome Res. 2012)
    6. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    7. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    8. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    9. A data set of human endogenous protein ubiquitination sites. (PubMed id 20972266)1 Shi Y....Qin J. (amp 2011)
    10. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 113178 HGNC: 30385 AceView: C19orf24 Ensembl:ENSG00000227500 euGenes: HUgn113178
    ECgene: SCAMP4 H-InvDB: SCAMP4

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for SCAMP4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for SCAMP4 gene:
    Search GeneIP for patents involving SCAMP4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for SCAMP4   OriGene RNAi products in human, mouse, rat for SCAMP4  
     OriGene qPCR primer pairs and template standards for SCAMP4   OriGene Protein Over-expression Lysate for SCAMP4  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for SCAMP4  
     OriGene qSTAR qPCR primer pairs in human, mouse for SCAMP4   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for SCAMP4   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for SCAMP4   OriGene Custom Protein Services for SCAMP4  

     
     
     Block miRNA regulation of human, mouse, rat SCAMP4 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing SCAMP4
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SCAMP4 Predesigned siRNA for gene silencing in human, mouse, rat SCAMP4
     QuantiFast Probe-based Assays in human, mouse, rat SCAMP4 QuantiTect SYBR Green Assays in human, mouse, rat SCAMP4
     Custom PCR Arrays for SCAMP4 Search Chromatin IP Primers for SCAMP4
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SCAMP4  Search GeneGlobe Interaction Network for SCAMP4
     Regulatory tfbs in SCAMP4 promoter
     GenScript Custom Purified and Recombinant Proteins Services for SCAMP4 GenScript cDNA clones with any tag delivered in your preferred vector for SCAMP4
     GenScript Custom Assay Services for SCAMP4 GenScript Custom overexpressing Cell Line Services for SCAMP4
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for SCAMP4 (SCAM4)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for SCAMP4
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     SCAMP4 antibodies
     SCAMP4 lysates
     Antibodies for SCAMP4
     See all of Abcam's Antibodies, Kits and Proteins for SCAMP4
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for SCAMP4
     Antibodies for SCAMP4
     ELISAs for SCAMP4
     CLIAs for SCAMP4



     Browse ESI BIO Cell Lines and PureStem Progenitors for SCAMP4
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCAMP4
     SwitchGear 3'UTR luciferase reporter plasmids for SCAMP4
     SwitchGear Promoter luciferase reporter plasmids for SCAMP4
     ThermoFisher Antibodies for SCAMP4
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCAMP4
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SCAMP4
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SCAMP4
     LSBio Antibodies in human, mouse, rat for SCAMP4
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      SCAMP4 gene at Home site.
    Version: 3.12.166 28 Aug 2014
    hostname: 356980-web2.xennexinc.com index build: 126 solr: 1.4