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SCAI Gene

protein-coding   GIFtS: 47
GCID: GC09M127704

Suppressor Of Cancer Cell Invasion

(Previous name: chromosome 9 open reading frame 126)
(Previous symbol: C9orf126)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Suppressor Of Cancer Cell Invasion1 2
C9orf1261 2 3
Suppressor Of Cancer Cell Invasion Protein2 3
Chromosome 9 Open Reading Frame 1261
NET402
Protein SCAI2

External Ids:    HGNC: 267091   Entrez Gene: 2862052   Ensembl: ENSG000001736117   UniProtKB: Q8N9R83   

Export aliases for SCAI gene to outside databases

Previous GC identifers: GC09M126755 GC09M097317


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SCAI Gene:
This gene encodes a regulator of cell migration. The encoded protein appears to function in the RhoA (ras homolog
gene family, member A)-Dia1 (diaphanous homolog 1) signal transduction pathway. Alternatively spliced transcript
variants have been described. (provided by RefSeq, Feb 2010)

GeneCards Summary for SCAI Gene:
SCAI (suppressor of cancer cell invasion) is a protein-coding gene. Diseases associated with SCAI include transient cerebral ischemia, and ischemia. GO annotations related to this gene include transcription corepressor activity.

UniProtKB/Swiss-Prot: SCAI_HUMAN, Q8N9R8
Function: Tumor suppressor which functions to suppress MKL1-induced SRF transcriptional activity. May function in
the RHOA-DIAPH1 signal transduction pathway and regulate cell migration through transcriptional regulation of
ITGB1




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000009.12  NT_008470.20  NC_018920.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for SCAI
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for SCAI

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SCAI


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q33.3   Ensembl cytogenetic band:  9q33.3   HGNC cytogenetic band: 9q34.11

SCAI Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SCAI gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M127704:  view genomic region     (about GC identifiers)

Start:
127,704,887 bp from pter      End:
127,905,838 bp from pter
Size:
200,952 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SCAI_HUMAN, Q8N9R8 (See protein sequence)
Recommended Name: Protein SCAI  
Size: 606 amino acids; 70399 Da
Subunit: Interacts with DIAPH1 (By similarity). Forms a nuclear ternary complex with MKL1 and SRF
Secondary accessions: Q3SXZ1 Q3SXZ2 Q5T163 Q8N1I4
Alternative splicing: 2 isoforms:  Q8N9R8-1   Q8N9R8-2   

Explore the universe of human proteins at neXtProt for SCAI: NX_Q8N9R8

Explore proteomics data for SCAI at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SCAI Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001138349.1  NP_775961.2  

    ENSEMBL proteins: 
     ENSP00000336756   ENSP00000419576   ENSP00000362650   ENSP00000418148   ENSP00000419358  

    SCAI Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
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    Cloud-Clone Corp. Proteins for SCAI

    SCAI Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Novus Biologicals SCAI Antibodies
    Abcam antibodies for SCAI
    Cloud-Clone Corp. Antibodies for SCAI
    ThermoFisher Antibodies for SCAI
    Search LSBio for Antibodies for SCAI

    SCAI Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SCAI
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SCAI
    Cloud-Clone Corp. CLIAs for SCAI


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR022709 SCAI
     IPR016607 SCAI_metazoan/Viridiplantae

    Graphical View of Domain Structure for InterPro Entry Q8N9R8

    ProtoNet protein and cluster: Q8N9R8

    UniProtKB/Swiss-Prot: SCAI_HUMAN, Q8N9R8
    Similarity: Belongs to the SCAI family


    SCAI for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SCAI_HUMAN, Q8N9R8
    Function: Tumor suppressor which functions to suppress MKL1-induced SRF transcriptional activity. May function in
    the RHOA-DIAPH1 signal transduction pathway and regulate cell migration through transcriptional regulation of
    ITGB1

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003714transcription corepressor activity IMP19350017
    GO:0005515protein binding IPI19350017
         
    SCAI for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SCAI:
     Decreased viability of wild-ty 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SCAI
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SCAI

    miRNA
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    Block miRNA regulation of human, mouse, rat SCAI using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SCAI (see all 162):
    hsa-miR-579 hsa-miR-361-5p hsa-miR-199a-3p hsa-miR-128 hsa-miR-519a hsa-miR-3622b-3p hsa-miR-298 hsa-miR-3909
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SCAI

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    Clone
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    OriGene ORF clones in mouse, rat for SCAI
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): SCAI (NM_173690)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SCAI
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCAI

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCAI


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SCAI_HUMAN, Q8N9R8: Membrane; Single-pass membrane protein (Potential). Nucleus. Cytoplasm. Note=Nuclear
    localization is required for inhibition of MKL1 (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    mitochondrion2

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--
    GO:0016021integral component of membrane IEA--

    SCAI for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SCAI
    Interactions:

        Search GeneGlobe Interaction Network for SCAI

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    Selected Interacting proteins for SCAI (Q8N9R83 ENSP000003626504) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TADA2BQ86TJ23I2D: score=5 
    RAD54LQ926983I2D: score=4 
    RPS8P622413I2D: score=4 
    SRFENSP000002653544STRING: ENSP00000265354
    ITGB1ENSP000003640944STRING: ENSP00000364094
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--
    GO:0030336negative regulation of cell migration IMP19350017
    GO:0035024negative regulation of Rho protein signal transduction ISS--

    SCAI for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SCAI



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SCAI gene (2 alternative transcripts): 
    NM_001144877.2  NM_173690.4  

    Unigene Cluster for SCAI:

    Suppressor of cancer cell invasion
    Hs.59504  [show with all ESTs]
    Unigene Representative Sequence: NM_173690
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000336505(uc004bpd.3 uc004bpe.3 uc010mwu.3) ENST00000477186
    ENST00000373549 ENST00000467917 ENST00000494102 ENST00000487795 ENST00000468569

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SCAI using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SCAI (see all 162):
    hsa-miR-579 hsa-miR-361-5p hsa-miR-199a-3p hsa-miR-128 hsa-miR-519a hsa-miR-3622b-3p hsa-miR-298 hsa-miR-3909
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for SCAI
    Predesigned siRNA for gene silencing in human, mouse, rat SCAI
    Clone
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    OriGene ORF clones in mouse, rat for SCAI
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): SCAI (NM_173690)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SCAI
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SCAI
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for SCAI
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SCAI
      QuantiTect SYBR Green Assays in human, mouse, rat SCAI
      QuantiFast Probe-based Assays in human, mouse, rat SCAI

    Additional mRNA sequence: 

    AF086497.1 AK021820.1 AK093983.1 AK098024.1 AL050012.1 BC029431.1 BC037940.1 BC104030.2 
    BC104031.1 

    12 DOTS entries:

    DT.100804252  DT.40116105  DT.305544  DT.86840618  DT.121162362  DT.91785959  DT.95368187  DT.40294444 
    DT.209436  DT.121193523  DT.40307222  DT.91851582 

    20 AceView cDNA sequences:

    AK093983 AX748393 AF086497 BX105452 NM_173690 W93859 AW978891 AK098024 
    AI015678 AW297952 W93898 AW298468 AA829836 CA424863 BC029431 N78319 
    BG497612 BI004178 AV754547 BG495801 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SCAI expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATTTTGTAC
    SCAI Expression
    About this image

    SCAI Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SCAI Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.59504
        Custom PCR Arrays for SCAI
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SCAI

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SCAI gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Scai1 , 5 suppressor of cancer cell invasion1, 5 91.53(n)1
    97.52(a)1
      2 (24.42 cM)5
    3202711  NM_178778.31  NP_848893.21 
     390662145 
    chicken
    (Gallus gallus)
    Aves SCAI1 suppressor of cancer cell invasion 84.54(n)
    97.52(a)
      427751  XM_425325.4  XP_425325.4 
    lizard
    (Anolis carolinensis)
    Reptilia SCAI6
    suppressor of cancer cell invasion
    90(a)
    1 ↔ 1
    GL344637.1(13049-24846)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.84132 Xenopus laevis transcribed sequence with weak similarity more 80.45(n)    AW158123.1 
    zebrafish
    (Danio rerio)
    Actinopterygii scai1 suppressor of cancer cell invasion 71.74(n)
    81.77(a)
      556383  XM_005171962.1  XP_005172019.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG132931 CG13293 55.07(n)
    55.31(a)
      38695  NM_001274534.1  NP_001261463.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G035701 AT3G03570 46.48(n)
    37.9(a)
      821234  NM_111228.3  NP_566209.1 


    ENSEMBL Gene Tree for SCAI (if available)
    TreeFam Gene Tree for SCAI (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SCAI gene
    1 SIMAP similar gene for SCAI using alignment to 3 protein entries:     SCAI_HUMAN (see all proteins):
    C9orf126

    SCAI for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SCAI (see all 3800)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs349989301,2
    C--127706676(+) AGGTT-/ACAAGC 2 -- ut311Minor allele frequency- A:0.00NA 2
    rs59006361,2
    C,F--127707467(+) CTATT-/A/AA  
            
    AAAAA
    4 -- ut312NA CSA 4
    rs114639801,2
    C--127707468(+) AAAAA-/A/AA  
            
    CTGAG
    4 -- ut310--------
    rs559380571,2
    C--127713339(+) AAAAA-/AAGTAAA 2 -- ut310--------
    rs20175061,2
    C,F,A--127716518(-) CGATTC/ATCCTG 2 -- ds50018Minor allele frequency- A:0.29NA WA CSA 14
    rs1891647491,2
    --127716614(+) AAACAA/GAAAGT 2 -- ds50010--------
    rs1123461201,2
    C--127716618(+) AAAAAG/ATCACG 2 -- ds50011Minor allele frequency- A:0.50CSA 2
    rs353155471,2
    C--127716645(+) TAAGTC/AAGGTC 2 -- ds50011Minor allele frequency- A:0.01EA 120
    rs1456472641,2
    --127716696(+) GAACTC/GTGGTT 2 -- ds50010--------
    rs1810306701,2
    --127716707(+) CCATCC/GCCAGA 2 -- ds50010--------

    HapMap Linkage Disequilibrium report for SCAI (127704887 - 127905838 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for SCAI:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2739041CNV Deletion23290073
    esv2442459CNV Deletion19546169
    nsv893839CNV Loss21882294
    nsv893838CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SCAI
    DNA2.0 Custom Variant and Variant Library Synthesis for SCAI

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    4 diseases for SCAI:    
    About MalaCards
    transient cerebral ischemia    ischemia    cerebritis    malaria

    1 disease from the University of Copenhagen DISEASES database for SCAI:
    Transient cerebral ischemia

    SCAI for disorders           About GeneDecksing

    Genetic Association Database (GAD): SCAI
    Human Genome Epidemiology (HuGE) Navigator: SCAI (6 documents)

    Export disorders for SCAI gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SCAI gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with SCAI)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin. (PubMed id 19350017)1, 2 Brandt D.T.... Grosse R. (Nat. Cell Biol. 2009)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (Nature 2004)
    5. Characterization and role of SCAI during renal fibrosis and epithelial-to-mesenchymal transition. (PubMed id 23178076)1 Fintha A....Sebe A. (Am. J. Pathol. 2013)
    6. Protein complex interactor analysis and differential activity of KDM3 subfamily members towards H3K9 methylation. (PubMed id 23593242)1 Brauchle M....Ruffner H. (PLoS ONE 2013)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    8. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    9. Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation. (PubMed id 20562864)1 Nozawa R.S.... Obuse C. (Nat. Cell Biol. 2010)
    10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 286205 HGNC: 26709 AceView: C9orf126 Ensembl:ENSG00000173611 euGenes: HUgn286205
    ECgene: SCAI H-InvDB: SCAI

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for SCAI Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SCAI gene:
    Search GeneIP for patents involving SCAI

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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