SC5DL Gene
protein-coding GIFtS: 59
GCID: GC11P121197
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|
sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S....(Previous names: sterol-C5-desaturase (fungal ERG3, delta-5-desaturase)-like,...)
| |
Aliases for SC5DL gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Sterol-C5-Desaturase (ERG3 Delta-5-Desaturase Homolog, S.Cerevisiae)-Like1 2 | | S5DES2 | | Delta(7)-Sterol 5-Desaturase2 3 | | SC5D2 | | Lathosterol 5-Desaturase2 3 | | Fungal ERG3, Delta-5-Desaturase-Like2 | | C-5 Sterol Desaturase2 3 | | Lathosterol Dehydrogenase2 | | ERG32 5 | | Lathosterol Oxidase2 | | Sterol-C5-Desaturase (ERG3 Delta-5-Desaturase Homolog, Fungal)-Like1 | | EC 1.14.21.63 | | Sterol-C5-Desaturase (Fungal ERG3, Delta-5-Desaturase)-Like1 | | Sterol-C5-Desaturase1 | | 3beta-Hydroxysteroid-Delta5-Desaturase1 | | |
Export aliases for SC5DL gene to outside databasesPrevious GC identifers: GC11P123163 GC11P122675 GC11P120701 GC11P120668 GC11P117105 |
Summaries for SC5DL gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for SC5DL: This gene encodes an enzyme of cholesterol biosynthesis. The encoded protein catalyzes the conversion of lathosterolinto 7-dehydrocholesterol. Mutations in this gene have been associated with lathosterolosis. Alternatively splicedtranscript variants encoding the same protein have been described. (provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: SC5D_HUMAN, O75845Function: Catalyzes a dehydrogenation to introduce C5-6 double bond into lathosterol Gene Wiki entry for SC5DL (Sterol-C5-desaturase-like)
|
Genomic Views for SC5DL gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_033899.8
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the SC5DL gene promoter: SREBP-1a GATA-1 ATF6 C/EBPalpha GATA-2 Other transcription factors
Search SABiosciences Chromatin IP Primers for SC5DL
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SC5DL |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q23.3 Ensembl cytogenetic band: 11q23.3 HGNC cytogenetic band: 11q23.3SC5DL Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11P121197: view genomic region
(about GC identifiers)
Start:
|
121,163,162 bp from pter |
End:
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121,184,119 bp from pter |
Size:
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20,958 bases |
Orientation:
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plus strand |
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Proteins for SC5DL gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: SC5D_HUMAN, O75845 (See
protein sequence)Recommended Name: Lathosterol oxidase Size: 299 amino acids; 35301 Da
Cofactor: Iron (By similarity)
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein (Probable)
Secondary accessions: O00119 Q9UK15Explore the universe of human proteins at neXtProt for SC5DL: NX_O75845
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O75845 SC5DL Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001020127.1 NP_008849.2 ENSEMBL proteins: ENSP00000264027 ENSP00000436290 ENSP00000432550 ENSP00000376539 Reactome Protein details: O75845 Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
SC5DL for ontologies About GeneDecksing
SC5DL Antibody Products: Assay Products for SC5DL: |
Protein
Domains / Families for SC5DL gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SC5DL for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry O75845ProtoNet protein and cluster: O75845 1 Blocks protein family: IPB006088 Sterol desaturase
UniProtKB/Swiss-Prot: SC5D_HUMAN, O75845Domain: The histidine box domains may contain the active site and/or be involved in metal ion bindingSimilarity: Belongs to the sterol desaturase family |
Function for SC5DL gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: SC5D_HUMAN, O75845Function: Catalyzes a dehydrogenation to introduce C5-6 double bond into lathosterolCatalytic activity: 5-alpha-cholest-7-en-3-beta-ol + NAD(P)H + O(2) = cholesta-5,7-dien-3-beta-ol + NAD(P)(+) + 2 H(2)O Genatlas biochemistry entry for SC5DL:sterol-C5-desaturase,fungal homolog Enzyme Number (IUBMB): EC 1.14.21.61
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SC5DL (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SC5DL (see all 3) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): SC5DL (NM_001024956) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SC5DL | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SC5DL  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SC5DL |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000248 | C-5 sterol desaturase activity |
IEA | -- | | GO:0005506 | iron ion binding |
IEA | -- | | GO:0016491 | oxidoreductase activity |
-- | -- | | GO:0050046 | lathosterol oxidase activity |
IEA | -- |
SC5DL for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for SC5DL: Animal Models: Mouse knock-out Sc5dtm1Fdp for SC5DL 13 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Sc5d):
SC5DL for phenotypes About GeneDecksing
|
Pathways & Interactions for SC5DL gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | cholesterol biosynthesis III (via desmosterol) | | | 2 | Metabolism | | | 3 | Cholesterol biosynthesis | | | 4 | Regulation of Cholesterol Biosynthesis by SREBP (SREBF) | | | 5 | Expression of Lathosterol Oxidase (SC5D, SC5DL) | |
Pathway sources See GeneCards unified pathways Show all pathways
5 BioSystems Pathways for SC5DL 
5/6
Reactome Pathways for SC5DL (see all 6)
2
Kegg Pathways (Kegg details for SC5DL):
SC5DL for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SC5DL
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/142 Interacting proteins for SC5DL (O758453 ENSP000002640274) via UniProtKB, MINT, STRING, and/or I2D (see all 142)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006629 | lipid metabolic process |
TAS | 8976377 | | GO:0006633 | fatty acid biosynthetic process |
IEA | -- | | GO:0006695 | cholesterol biosynthetic process |
TAS | -- | | GO:0033490 | cholesterol biosynthetic process via lathosterol |
IEA | -- | | GO:0044281 | small molecule metabolic process |
TAS | -- |
SC5DL for ontologies About GeneDecksing
|
Drugs & Compounds for SC5DL gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SC5DL for compounds About GeneDecksing
Browse Tocris compounds for SC5DL
10/15 HMDB Compounds for SC5DL (see all 15) About this table 6 Novoseek chemical compound relationships for SC5DL gene About this table
Search CenterWatch for drugs/clinical trials and news about SC5DL / SC5D 
|
Transcripts for SC5DL gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for SC5DL gene (2 alternative transcripts): NM_001024956.2 NM_006918.4 Unigene Cluster for SC5DL: Sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like Hs.287749 [show with all ESTs]Unigene Representative Sequence: NM_0010249569 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000264027(uc001pxt.3 uc001pxu.3) ENST00000534455 ENST00000531140 ENST00000524683(uc001pxs.1) ENST00000527762 ENST00000534230 ENST00000392789(uc001pxv.3) ENST00000528991 ENST00000527183
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SC5DL (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SC5DL (see all 3) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): SC5DL (NM_001024956) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SC5DL | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SC5DL  |
Additional cDNA sequence: AF069469.1 AF187981.1 AK027246.1 AK222686.1 AK223141.1 AK312634.1 BC012333.1 BC050427.1 13 DOTS entries: DT.87045635 DT.95329074 DT.100795276 DT.120689356 DT.95329066 DT.95329070 DT.92471906 DT.100795280 DT.100795278 DT.120689362 DT.120689373 DT.100000910 DT.95329072 24/315 AceView cDNA sequences (see all 315): BI494086 BM314114 BM721058 BX495986 BM721025 F11632 BX478737 AU130431 BG740027 BM683012 BF792424 AI394121 CB164483 AA639446 AI301316 BM510014 AI479481 AA868151 AV653958 AW235339 BU145531 AW020609 N91268 BM313833 GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for SC5DL About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | |
| SP1: | |   | |   | - |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | - |   | - |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for SC5DL
|
Expression for SC5DL gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SC5DL expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: ATTTAATCCA
About this image See SC5DL Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for SC5DL
SOURCE GeneReport for Unigene cluster: Hs.287749 SABiosciences Custom PCR Arrays for SC5DL
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SC5DL Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SC5DL | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SC5DL | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SC5DL | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SC5DL |
Orthologs for SC5DL gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SC5DL gene from 7/22 species (see all 22) About this table
ENSEMBL Gene Tree for SC5DL (if available) TreeFam Gene Tree for SC5DL (if available)  |
Paralogs for SC5DL gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for SC5DL gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 11 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for SC5DL (121163162 - 121184119 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for SC5DL: -- Human Gene Mutation Database (HGMD): SC5DL
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SC5DL |
|
Disorders
/ Diseases for SC5DL gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SC5DL for disorders About GeneDecksing
OMIM gene information: 602286 OMIM disorders: 607330 UniProtKB/Swiss-Prot: SC5D_HUMAN, O75845
Defects in SC5DL are the cause of lathosterolosis (LATHST) [MIM:607330]. This autosomal recessive disorder ischaracterized by a complex phenotype, including multiple congenital anomalies, mental retardation, and liver disease 6 diseases for SC5DL: About MalaCardslathosterolosis smith-lemli-opitz syndrome cholesterol mental retardation syndrome mucolipidosis schizophrenia 1 disease from the University of Copenhagen DISEASES database for SC5DL:Smith-Lemli-Opitz syndrome 1 Novoseek disease relationship for SC5DL gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| lathosterolosis |
95.5 |
1 |
12812989 (1) |
Human Genome Epidemiology (HuGE) Navigator: SC5DL (4 documents) Export disorders for SC5DL gene to outside databases
|
Publications for SC5DL gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SC5DL gene, integrated from 9 sources (see all 33): (articles sorted by number of sources associating them with SC5DL) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Molecular cloning and mapping of a human cDNA(SC5DL) encoding a protein homologous to fungal sterol-C5-desaturase. (PubMed id 8976377)1, 2, 3, 9 Matsushima M.... Nakamura Y. (1996)
- Molecular cloning and structural analysis of human sterol C5 desaturase. (PubMed id 11731337)1, 6, 9 Sugawara T....Ishibashi T. (2001)
- Lathosterolosis: an inborn error of human and murine cholesterol synthesis due to lathosterol 5-desaturase deficiency. (PubMed id 12812989)1, 2, 9 Krakowiak P.A.... Porter F.D. (2003)
- cDNA cloning of the mammalian sterol C5-desaturase and the expression in yeast mutant. (PubMed id 10786622)1, 2, 9 Nishi S.... Ishibashi T. (2000)
- Lathosterolosis, a novel multiple-malformation/mental retardation syndrome due to deficiency of 3beta-hydroxysteroid-delta5- desaturase. (PubMed id 12189593)1, 2, 9 Brunetti-Pierri N....Parenti G. (2002)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Delta7-sterol-C5-desaturase: molecular characterization and functional expression of wild-type and mutant alleles. (PubMed id 10344195)1, 2 Husselstein T.... Benveniste P. (1999)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
|
External Searches for SC5DL gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing SC5DL gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SC5DL gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SC5DL gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for SC5DL | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SC5DL gene: Search GeneIP for patents involving SC5DL
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for SC5DL gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
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variant library, vector shuttling | | OriGene Custom Antibody Services for SC5DL | | OriGene Custom Protein Services for SC5DL | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SC5DL | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SC5DL | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SC5DL | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SC5DL | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SC5DL | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SC5DL |
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| | | Search Tocris compounds for SC5DL |
| |  |  |  |  | | | | |
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 | | SC5DL Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SC5DL |
|  |  |  | | | Search ThermoFisher Antibodies for SC5DL |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SC5DL |
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