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Aliases for SBNO1 Gene

Aliases for SBNO1 Gene

  • Strawberry Notch Homolog 1 (Drosophila) 2 3
  • Monocyte Protein 3 3 4
  • MOP3 3 4
  • Sno, Strawberry Notch Homolog 1 (Drosophila) 2
  • Protein Strawberry Notch Homolog 1 3
  • MOP-3 4
  • SNO 3

External Ids for SBNO1 Gene

Previous GeneCards Identifiers for SBNO1 Gene

  • GC12M123587
  • GC12M122216
  • GC12M122217
  • GC12M122305
  • GC12M123780
  • GC12M120734
  • GC12M123774

Summaries for SBNO1 Gene

GeneCards Summary for SBNO1 Gene

SBNO1 (Strawberry Notch Homolog 1 (Drosophila)) is a Protein Coding gene. An important paralog of this gene is SBNO2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SBNO1 Gene

Genomics for SBNO1 Gene

Regulatory Elements for SBNO1 Gene

Genomic Location for SBNO1 Gene

Start:
123,289,109 bp from pter
End:
123,365,257 bp from pter
Size:
76,149 bases
Orientation:
Minus strand

Genomic View for SBNO1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SBNO1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SBNO1 Gene

Proteins for SBNO1 Gene

  • Protein details for SBNO1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A3KN83-SBNO1_HUMAN
    Recommended name:
    Protein strawberry notch homolog 1
    Protein Accession:
    A3KN83
    Secondary Accessions:
    • Q05C06
    • Q3ZTS3
    • Q9H3T8
    • Q9NVB2

    Protein attributes for SBNO1 Gene

    Size:
    1393 amino acids
    Molecular mass:
    154312 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAQ76814.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for SBNO1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SBNO1 Gene

Proteomics data for SBNO1 Gene at MOPED

Post-translational modifications for SBNO1 Gene

  • Ubiquitination at Lys155 and Lys378
  • Modification sites at PhosphoSitePlus

Other Protein References for SBNO1 Gene

No data available for DME Specific Peptides for SBNO1 Gene

Domains for SBNO1 Gene

Protein Domains for SBNO1 Gene

Suggested Antigen Peptide Sequences for SBNO1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A3KN83

UniProtKB/Swiss-Prot:

SBNO1_HUMAN :
  • A3KN83
Family:
  • Belongs to the SBNO family.
genes like me logo Genes that share domains with SBNO1: view

No data available for Gene Families for SBNO1 Gene

Function for SBNO1 Gene

Gene Ontology (GO) - Molecular Function for SBNO1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0003677 DNA binding --
GO:0003824 catalytic activity --
GO:0005524 ATP binding --
GO:0016491 oxidoreductase activity --
genes like me logo Genes that share ontologies with SBNO1: view

Phenotypes for SBNO1 Gene

GenomeRNAi human phenotypes for SBNO1:
genes like me logo Genes that share phenotypes with SBNO1: view

Animal Model Products

miRNA for SBNO1 Gene

miRTarBase miRNAs that target SBNO1

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SBNO1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for SBNO1 Gene

Localization for SBNO1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SBNO1 Gene COMPARTMENTS Subcellular localization image for SBNO1 gene
Compartment Confidence
nucleus 3
cytosol 1

Gene Ontology (GO) - Cellular Components for SBNO1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with SBNO1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for SBNO1 Gene

Pathways for SBNO1 Gene

SuperPathways for SBNO1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SBNO1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0008150 biological_process ND --
GO:0055114 oxidation-reduction process --
genes like me logo Genes that share ontologies with SBNO1: view

No data available for Pathways by source for SBNO1 Gene

Transcripts for SBNO1 Gene

Unigene Clusters for SBNO1 Gene

Strawberry notch homolog 1 (Drosophila):
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SBNO1

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SBNO1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7: -

ExUns: 25 ^ 26 ^ 27 ^ 28 ^ 29 ^ 30 ^ 31 ^ 32 ^ 33
SP1:
SP2:
SP3: -
SP4:
SP5:
SP6:
SP7:

Relevant External Links for SBNO1 Gene

GeneLoc Exon Structure for
SBNO1
ECgene alternative splicing isoforms for
SBNO1

Expression for SBNO1 Gene

mRNA expression in normal human tissues for SBNO1 Gene

Protein differential expression in normal tissues for SBNO1 Gene

This gene is overexpressed in Testis (28.8), Peripheral blood mononuclear cells (8.7), and Fetal ovary (6.8).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for SBNO1 Gene

SOURCE GeneReport for Unigene cluster for SBNO1 Gene Hs.7012

genes like me logo Genes that share expressions with SBNO1: view

Expression partners for SBNO1 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SBNO1 Gene

Orthologs for SBNO1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for SBNO1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia SBNO1 35
  • 93.41 (n)
  • 98.13 (a)
SBNO1 36
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SBNO1 35
  • 94.09 (n)
  • 98.13 (a)
SBNO1 36
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Sbno1 35
  • 89.33 (n)
  • 97.19 (a)
Sbno1 16
Sbno1 36
  • 97 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia SBNO1 35
  • 99.71 (n)
  • 99.93 (a)
SBNO1 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Sbno1 35
  • 89.58 (n)
  • 97.19 (a)
oppossum
(Monodelphis domestica)
Mammalia SBNO1 36
  • 89 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 86 (a)
OneToMany
-- 36
  • 95 (a)
OneToMany
-- 36
  • 95 (a)
OneToMany
-- 36
  • 96 (a)
OneToMany
chicken
(Gallus gallus)
Aves SBNO1 35
  • 82.33 (n)
  • 92.66 (a)
SBNO1 36
  • 92 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SBNO1 36
  • 79 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia sbno1 35
  • 76.74 (n)
  • 87.13 (a)
Str.16725 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.19331 35
zebrafish
(Danio rerio)
Actinopterygii Dr.25585 35
sbno1 35
  • 70.25 (n)
  • 81.23 (a)
SBNO1 36
  • 19 (a)
OneToOne
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.13697 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP011199 35
  • 26.36 (n)
  • 5.16 (a)
fruit fly
(Drosophila melanogaster)
Insecta sno 35
  • 58.24 (n)
  • 62.51 (a)
CG3491 36
  • 33 (a)
ManyToMany
sno 36
  • 38 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea let-765 35
  • 59.86 (n)
  • 61.06 (a)
let-765 36
  • 32 (a)
OneToMany
thale cress
(Arabidopsis thaliana)
eudicotyledons EMB1135 35
  • 52.06 (n)
  • 47.02 (a)
rice
(Oryza sativa)
Liliopsida Os.14486 35
Os08g0223700 35
  • 53.25 (n)
  • 49.2 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.5929 35
sea squirt
(Ciona savignyi)
Ascidiacea CSA.5085 36
  • 51 (a)
OneToMany
Species with no ortholog for SBNO1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SBNO1 Gene

ENSEMBL:
Gene Tree for SBNO1 (if available)
TreeFam:
Gene Tree for SBNO1 (if available)

Paralogs for SBNO1 Gene

Paralogs for SBNO1 Gene

Selected SIMAP similar genes for SBNO1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SBNO1: view

Variants for SBNO1 Gene

Sequence variations from dbSNP and Humsavar for SBNO1 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs1060105 -, - 123,321,672(-) TAGCA(A/G)TTCTG missense, reference
rs1064748 -- 123,320,817(-) AAAAA(A/G)AAGAA synonymous-codon, reference
rs1064749 -- 123,320,814(-) AAGAA(A/G)AAAAG synonymous-codon, reference
rs2277343 -- 123,309,903(-) AAAAA(A/T)TTTTA intron-variant
rs2277344 -- 123,309,889(-) ATCAT(G/T)TGCAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SBNO1 Gene

Variant ID Type Subtype PubMed ID
esv2746502 CNV Deletion 23290073
esv2746503 CNV Deletion 23290073
esv2746504 CNV Deletion 23290073

Relevant External Links for SBNO1 Gene

HapMap Linkage Disequilibrium report
SBNO1
Human Gene Mutation Database (HGMD)
SBNO1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SBNO1 Gene

Disorders for SBNO1 Gene

Relevant External Links for SBNO1

Genetic Association Database (GAD)
SBNO1
Human Genome Epidemiology (HuGE) Navigator
SBNO1

No disorders were found for SBNO1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for SBNO1 Gene

Publications for SBNO1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  3. Biological, clinical and population relevance of 95 loci for blood lipids. (PMID: 20686565) Teslovich T.M. … Kathiresan S. (Nature 2010) 3 48
  4. Hundreds of variants clustered in genomic loci and biological pathways affect human height. (PMID: 20881960) Lango Allen H. … Hirschhorn J.N. (Nature 2010) 3 48
  5. Common variants at 12q15 and 12q24 are associated with infant head circumference. (PMID: 22504419) Taal H.R. … Jaddoe V.W. (Nat. Genet. 2012) 3 48

Products for SBNO1 Gene

Sources for SBNO1 Gene

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