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Aliases for SBNO1 Gene

Aliases for SBNO1 Gene

  • Strawberry Notch Homolog 1 (Drosophila) 2 3 5
  • Monocyte Protein 3 3 4
  • MOP3 3 4
  • Sno, Strawberry Notch Homolog 1 (Drosophila) 2
  • MOP-3 4
  • Sno 3

External Ids for SBNO1 Gene

Previous GeneCards Identifiers for SBNO1 Gene

  • GC12M123587
  • GC12M122216
  • GC12M122217
  • GC12M122305
  • GC12M123780
  • GC12M120734
  • GC12M123774

Summaries for SBNO1 Gene

GeneCards Summary for SBNO1 Gene

SBNO1 (Strawberry Notch Homolog 1 (Drosophila)) is a Protein Coding gene. GO annotations related to this gene include oxidoreductase activity and hydrolase activity. An important paralog of this gene is SBNO2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SBNO1 Gene

Genomics for SBNO1 Gene

Regulatory Elements for SBNO1 Gene

Promoters for SBNO1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around SBNO1 on UCSC Golden Path with GeneCards custom track

Genomic Location for SBNO1 Gene

123,289,109 bp from pter
123,365,525 bp from pter
76,417 bases
Minus strand

Genomic View for SBNO1 Gene

Genes around SBNO1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SBNO1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SBNO1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SBNO1 Gene

Proteins for SBNO1 Gene

  • Protein details for SBNO1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein strawberry notch homolog 1
    Protein Accession:
    Secondary Accessions:
    • Q05C06
    • Q3ZTS3
    • Q9H3T8
    • Q9NVB2

    Protein attributes for SBNO1 Gene

    1393 amino acids
    Molecular mass:
    154312 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAQ76814.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for SBNO1 Gene


neXtProt entry for SBNO1 Gene

Proteomics data for SBNO1 Gene at MOPED

Post-translational modifications for SBNO1 Gene

  • Ubiquitination at Lys 155 and Lys 378
  • Modification sites at PhosphoSitePlus

Other Protein References for SBNO1 Gene

No data available for DME Specific Peptides for SBNO1 Gene

Domains & Families for SBNO1 Gene

Protein Domains for SBNO1 Gene

Suggested Antigen Peptide Sequences for SBNO1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the SBNO family.
  • Belongs to the SBNO family.
genes like me logo Genes that share domains with SBNO1: view

No data available for Gene Families for SBNO1 Gene

Function for SBNO1 Gene

genes like me logo Genes that share phenotypes with SBNO1: view

Animal Model Products

miRNA for SBNO1 Gene

miRTarBase miRNAs that target SBNO1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SBNO1 Gene

Localization for SBNO1 Gene

Subcellular locations from

Jensen Localization Image for SBNO1 Gene COMPARTMENTS Subcellular localization image for SBNO1 gene
Compartment Confidence
nucleus 4
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for SBNO1 Gene

Pathways & Interactions for SBNO1 Gene

SuperPathways for SBNO1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SBNO1 Gene


No data available for Pathways by source and SIGNOR curated interactions for SBNO1 Gene

Drugs & Compounds for SBNO1 Gene

No Compound Related Data Available

Transcripts for SBNO1 Gene

Unigene Clusters for SBNO1 Gene

Strawberry notch homolog 1 (Drosophila):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SBNO1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^
SP7: -

ExUns: 25 ^ 26 ^ 27 ^ 28 ^ 29 ^ 30 ^ 31 ^ 32 ^ 33
SP3: -

Relevant External Links for SBNO1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SBNO1 Gene

mRNA expression in normal human tissues for SBNO1 Gene

Protein differential expression in normal tissues from HIPED for SBNO1 Gene

This gene is overexpressed in Testis (28.8), Peripheral blood mononuclear cells (8.7), and Fetal ovary (6.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for SBNO1 Gene

SOURCE GeneReport for Unigene cluster for SBNO1 Gene Hs.7012

genes like me logo Genes that share expression patterns with SBNO1: view

Protein tissue co-expression partners for SBNO1 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SBNO1 Gene

Orthologs for SBNO1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for SBNO1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SBNO1 35
  • 93.41 (n)
  • 98.13 (a)
SBNO1 36
  • 98 (a)
(Canis familiaris)
Mammalia SBNO1 35
  • 94.09 (n)
  • 98.13 (a)
SBNO1 36
  • 98 (a)
(Mus musculus)
Mammalia Sbno1 35
  • 89.33 (n)
  • 97.19 (a)
Sbno1 16
Sbno1 36
  • 97 (a)
(Pan troglodytes)
Mammalia SBNO1 35
  • 99.71 (n)
  • 99.93 (a)
SBNO1 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Sbno1 35
  • 89.58 (n)
  • 97.19 (a)
(Monodelphis domestica)
Mammalia SBNO1 36
  • 89 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 86 (a)
-- 36
  • 95 (a)
-- 36
  • 95 (a)
-- 36
  • 96 (a)
(Gallus gallus)
Aves SBNO1 35
  • 82.33 (n)
  • 92.66 (a)
SBNO1 36
  • 92 (a)
(Anolis carolinensis)
Reptilia SBNO1 36
  • 79 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia sbno1 35
  • 76.74 (n)
  • 87.13 (a)
Str.16725 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.19331 35
(Danio rerio)
Actinopterygii Dr.25585 35
sbno1 35
  • 70.25 (n)
  • 81.23 (a)
SBNO1 36
  • 19 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.13697 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP011199 35
  • 26.36 (n)
  • 5.16 (a)
fruit fly
(Drosophila melanogaster)
Insecta sno 35
  • 58.24 (n)
  • 62.51 (a)
CG3491 36
  • 33 (a)
sno 36
  • 38 (a)
(Caenorhabditis elegans)
Secernentea let-765 35
  • 59.86 (n)
  • 61.06 (a)
let-765 36
  • 32 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons EMB1135 35
  • 52.06 (n)
  • 47.02 (a)
(Oryza sativa)
Liliopsida Os.14486 35
Os08g0223700 35
  • 53.25 (n)
  • 49.2 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.5929 35
sea squirt
(Ciona savignyi)
Ascidiacea CSA.5085 36
  • 51 (a)
Species with no ortholog for SBNO1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SBNO1 Gene

Gene Tree for SBNO1 (if available)
Gene Tree for SBNO1 (if available)

Paralogs for SBNO1 Gene

Paralogs for SBNO1 Gene

(1) SIMAP similar genes for SBNO1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SBNO1: view

Variants for SBNO1 Gene

Sequence variations from dbSNP and Humsavar for SBNO1 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
VAR_037910 A breast cancer sample
rs1060105 -, - 123,321,672(-) TAGCA(A/G)TTCTG reference, missense
VAR_037912 A breast cancer sample
VAR_037913 A breast cancer sample
rs1064748 -- 123,320,817(-) AAAAA(A/G)AAGAA reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for SBNO1 Gene

Variant ID Type Subtype PubMed ID
esv2746502 CNV Deletion 23290073
esv2746503 CNV Deletion 23290073
esv2746504 CNV Deletion 23290073

Variation tolerance for SBNO1 Gene

Residual Variation Intolerance Score: 1.95% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.13; 80.63% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SBNO1 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SBNO1 Gene

Disorders for SBNO1 Gene

Relevant External Links for SBNO1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SBNO1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SBNO1 Gene

Publications for SBNO1 Gene

  1. Common variants at 12q15 and 12q24 are associated with infant head circumference. (PMID: 22504419) Taal H.R. … Jaddoe V.W. (Nat. Genet. 2012) 3 48 67
  2. Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation. (PMID: 25921289) Emdal K.B. … Olsen J.V. (Sci Signal 2015) 3
  3. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3
  4. Biological insights from 108 schizophrenia-associated genetic loci. (PMID: 25056061) (Nature 2014) 3
  5. Common genetic variants associated with cognitive performance identified using the proxy-phenotype method. (PMID: 25201988) Rietveld C.A. … Koellinger P.D. (Proc. Natl. Acad. Sci. U.S.A. 2014) 3

Products for SBNO1 Gene

Sources for SBNO1 Gene

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