SBF2 Gene
protein-coding GIFtS: 53
GCID: GC11M009800
|
|
SET binding factor 2(Previous names: Charcot-Marie-Tooth neuropathy 4B2 (autosomal recessive,...)
(Previous symbol: CMT4B2)
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Aliases
for SBF2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| SET Binding Factor 21 2 | | KIAA17661 3 | | CMT4B21 2 3 5 | | Charcot-Marie-Tooth Neuropathy 4B2 (Autosomal Recessive, With MyelinOutfolding)1 | | MTMR131 2 3 5 | | Myotubularin-Related Protein 132 | | DENND7B1 2 | | SET-Binding Factor 23 | | DENN/MADD Domain Containing 7B1 2 | | |
Export aliases for SBF2 gene to outside databasesPrevious GC identifers: GC11M009757 GC11M009472 |
Summaries
for SBF2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SBF2:
This gene encodes a pseudophosphatase and member of the myotubularin-related protein family. This gene maps within theCMT4B2 candidate region of chromosome 11p15 and mutations in this gene have been associated with Charcot-Marie-ToothDisease, type 4B2. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: MTMRD_HUMAN, Q86WG5Function: Guanine nucleotide exchange factor (GEF) which may activate RAB28. Promotes the exchange of GDP to GTP,converting inactive GDP-bound Rab proteins into their active GTP-bound form
Gene Wiki entry for SBF2
|
Genomic Views
for SBF2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_009237.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SBF2 gene promoter:
AP-2alpha isoform 3 AP-2alpha isoform 4 AP-2alpha isoform 2 AP-2alpha AP-2alphaA
Other transcription factors
Search SABiosciences Chromatin IP Primers for SBF2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SBF2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11p15.4 Ensembl cytogenetic band: 11p15.4 HGNC cytogenetic band: 11p15.3SBF2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M009800: view genomic region
(about GC identifiers)
Start:
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9,800,214 bp from pter |
End:
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10,315,754 bp from pter |
Size:
|
515,541 bases |
Orientation:
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minus strand |
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Proteins
for SBF2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MTMRD_HUMAN, Q86WG5 (See
protein sequence)Recommended Name: Myotubularin-related protein 13 Size: 1849 amino acids; 208464 Da
Subunit: Interacts with MTMR2
Subcellular location: Cytoplasm. Membrane; Peripheral membrane protein. Note=Associated with membranes
Caution: In contrast to other members of the family, it lacks a canonical protein-tyrosine phosphatase domain and lacksthe conserved Cys residue in position 1410 which is replaced by a Leu residue. It therefore probably does not havephosphatase activity
Secondary accessions: Q3MJF0 Q68DQ3 Q6P459 Q6PJD1 Q7Z325 Q7Z621 Q86VE2 Q96FE2 Q9C097Alternative splicing: 2 isoforms: Q86WG5-1 Q86WG5-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SBF2: NX_Q86WG5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q86WG5
SBF2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_112224.1
ENSEMBL proteins: ENSP00000256190 ENSP00000434620 ENSP00000432643 ENSP00000410478
Human Recombinant Protein Products for SBF2:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
SBF2 for ontologies About GeneDecksing
SBF2 Antibody Products:
Assay Products for SBF2: |
Protein
Domains /
Families
for SBF2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SBF2 for domains About GeneDecksing
5/9 InterPro domains/families (see all 9):Graphical View of Domain Structure for InterPro Entry Q86WG5ProtoNet protein and cluster: Q86WG5 2 Blocks protein families: IPB001849 Pleckstrin-like IPB004182 GRAM domain
UniProtKB/Swiss-Prot: MTMRD_HUMAN, Q86WG5Similarity: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamilySimilarity: Contains 1 dDENN domainSimilarity: Contains 1 DENN domainSimilarity: Contains 1 GRAM domainSimilarity: Contains 1 myotubularin phosphatase domainSimilarity: Contains 1 PH domainSimilarity: Contains 1 uDENN domain |
Function
for SBF2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: MTMRD_HUMAN, Q86WG5Function: Guanine nucleotide exchange factor (GEF) which may activate RAB28. Promotes the exchange of GDP to GTP,converting inactive GDP-bound Rab proteins into their active GTP-bound form Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table
SBF2 for ontologies About GeneDecksing
Phenotypes:
3 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Sbf2):
SBF2 for phenotypes About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SBF2 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SBF2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SBF2 (NM_030962) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SBF2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SBF2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SBF2 |
|
Pathways & Interactions
for SBF2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SBF2
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
4 Interacting proteins for SBF2 (Q86WG53 ENSP000002561904) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
SBF2 for ontologies About GeneDecksing
|
Drugs & Compounds
for SBF2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SBF2
Search CenterWatch for drugs/clinical trials and news about SBF2 / MTMRD
|
Transcripts
for SBF2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SBF2 gene: NM_030962.3 Unigene Cluster for SBF2: SET binding factor 2 Hs.577252 [show with all ESTs]Unigene Representative Sequence: NM_03096214 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000256190(uc001mic.2 uc001mid.2 uc001mib.2) ENST00000525040
ENST00000529587 ENST00000532095 ENST00000528478 ENST00000525697 ENST00000530741
ENST00000524961 ENST00000533584 ENST00000533770(uc001mif.3) ENST00000420722
ENST00000526353(uc001mih.4) ENST00000527019 ENST00000533661
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SBF2 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SBF2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SBF2 (NM_030962) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SBF2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SBF2 |
Additional cDNA sequence: AB051553.1 AF085830.1 AK022478.1 AK026571.1 AK091362.1 AK123621.1 AL512756.1 AL832942.1 AY234241.1 BC011143.1 BC027492.1 BC043389.1 BC053867.1 BC063656.1 BC101466.1 BX538184.1 BX647533.1 CR749312.1 15 DOTS entries: DT.313555 DT.40213458 DT.91957512 DT.101969480 DT.95326543 DT.100736649 DT.95293345 DT.100750046 DT.75134541 DT.97837682 DT.100639703 DT.120715513 DT.75154979 DT.91686032 DT.95075484 24/138 AceView cDNA sequences (see all 138): BQ774853 BM702128 AA598451 NM_030962 BM461560 AY234241 AI754979 BQ446647 H88098 AI831899 AL512756 Z44474 D79793 BX647533 CR611690 AA630746 BC063656 BC027492 BM664833 BM806984 AB051553 BQ720683 CR603765 BX644333
GeneLoc Exon Structure
|
Expression
for SBF2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SBF2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTAAACAGAA
About this image
See SBF2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SBF2
SOURCE GeneReport for Unigene cluster: Hs.577252
UniProtKB/Swiss-Prot: MTMRD_HUMAN, Q86WG5Tissue specificity: Widely expressed. Expressed in spinal cord
SABiosciences Custom PCR Arrays for SBF2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SBF2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SBF2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SBF2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SBF2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SBF2 |
Orthologs
for SBF2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SBF2 gene from 8/25 species (see all 25) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
SBF21 |
SET binding factor 2 |
78.81(n)
86.12(a) |
|
423043 NM_001012895.2 NP_001012913.2 |
lizard
(Anolis carolinensis) |
Reptilia |
SBF26 |
-- |
88(a) |
1 ↔ 1 |
1(63807826-63980799) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.86492 |
Xenopus laevis transcribed sequence with weak similarity to protein pirT00375 (H.sapiens) T00375 hypothetical protein KIAA0647 - human (fragment) less |
73.75(n) |
|
CA792031.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
BM534438.12 |
-- |
75.12(n) |
|
BM534438.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Sbf1 |
SET domain binding factor |
51.87(n)
45.84(a) |
|
41427 NM_169430.2 NP_731633.2 |
worm
(Caenorhabditis elegans) |
Secernentea |
mtm-51 |
Protein MTM-5 |
42.66(n)
31.03(a) |
|
180792 NM_076487.2 NP_508888.2 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT5G045406MTM16 |
Myotubularin-like phosphatases II-like protein |
17(a)16(a) |
many ↔ manymany ↔ many |
5(1296442-1302444) 3(3292899-3298522) |
rice
(Oryza sativa) |
Liliopsida |
-- |
inositol or phosphatidylinositol phosphatase/ phos... |
16(a) |
1 → many |
8(27856282-27865603) |
ENSEMBL Gene Tree for SBF2 (if available)
TreeFam Gene Tree for SBF2 (if available) |
Paralogs
for SBF2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SBF2 gene
- MTMR42 MTMR72 MTMR122 MTMR22 MTMR102 MTM12 MTMR82 MTMR32
- MTMR92 MTMR62 MTMR112 SBF12 MTMR12
3 SIMAP similar genes for SBF2 using alignment to 4 protein entries: MTMRD_HUMAN (see all proteins):DKFZp666I2310 DKFZp761D0422 SBF1
SBF2 for paralogs About GeneDecksing
|
Genomic Variants
for SBF2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SBF2 (9800214 - 10050214 bp, first 250kb of SBF2)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 28 variations for SBF2
15 CNVs: 48932 43835 61099 35031 48680 43812 101135 101134 39067 65864 0143 43267 85647 101133 48679
13 Indels: 85648 33539 75538 33538 75540 85649 85645 85646 33235 75542 75539 48931 75541
Human Gene Mutation Database (HGMD): SBF2
Locus Specific Mutation Databases (LSDB): SBF2
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SBF2 |
|
Disorders
/ Diseases
for SBF2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SBF2 for disorders About GeneDecksing
OMIM gene information: 607697
OMIM disorders: 604563
UniProtKB/Swiss-Prot: MTMRD_HUMAN, Q86WG5
Defects in SBF2 are the cause of Charcot-Marie-Tooth disease type 4B2 (CMT4B2) [MIM:604563]. CMT4B2 is arecessive form of Charcot-Marie-Tooth disease, the most common inherited disorder of the peripheral nervous system.Charcot-Marie-Tooth disease is classified in two main groups on the basis of electrophysiologic properties andhistopathology: primary peripheral demyelinating neuropathy and primary peripheral axonal neuropathy. DemyelinatingCMT neuropathies are characterized by severely reduced nerve conduction velocities (less than 38 m/sec), segmentaldemyelination and remyelination with onion bulb formations on nerve biopsy, slowly progressive distal muscle atrophyand weakness, absent deep tendon reflexes, and hollow feet. By convention, autosomal recessive forms of demyelinatingCharcot-Marie-Tooth disease are designated CMT4. CMT4B2 is characterized by abnormal folding of myelin sheaths
15  diseases for SBF2: About MalaCardscharcot-marie-tooth disease type 4b2 charcot-marie-tooth disease type 4 charcot-marie-tooth disease charcot-marie-tooth neuropathy
charcot-marie-tooth neuropathy type 4 charcot-marie-tooth neuropathy type 4b2 tooth disease neuropathy
early-onset glaucoma centronuclear myopathy axonal neuropathy glaucoma
peripheral neuropathy myopathy cholesterol
2 diseases from the University of Copenhagen DISEASES database for SBF2:Neuropathy Myopathy 5 Novoseek disease relationships for SBF2 gene About this table
GeneTests: SBF2
Charcot-Marie-Tooth Neuropathy Type 4
Human Genome Epidemiology (HuGE) Navigator: SBF2 (3 documents)
Export disorders for SBF2 gene to outside databases
|
Publications
for SBF2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SBF2 gene, integrated from 9 sources (see all 33):
(articles sorted by number of sources associating them with SBF2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Mutation of the SBF2 gene, encoding a novel member of the myotubularin family, in Charcot-Marie-Tooth neuropathy type 4B2/11p15. (PubMed id 12554688)1, 2, 9 Senderek J.... Zerres K. (2003)
- The phosphoinositide-3-phosphatase MTMR2 associates with MTMR13, a membrane-associated pseudophosphatase also mutated in type 4B Charcot- Marie-Tooth disease. (PubMed id 15998640)1, 2, 9 Robinson F.L. and Dixon J.E. (2005)
- SET binding factor 2 (SBF2) mutation causes CMT4B with juvenile onset glaucoma. (PubMed id 15304601)1, 2, 9 Hirano R....Arimura K. (2004)
- Mutations in MTMR13, a new pseudophosphatase homologue of MTMR2 and Sbf1, in two families with an autosomal recessive demyelinating form of Charcot-Marie-Tooth disease associated with early-onset glaucoma. (PubMed id 12687498)1, 2, 9 Azzedine H.... LeGuern E. (2003)
- A new SBF2 mutation in a family with recessive demyelinating Charcot- Marie-Tooth (CMT4B2). (PubMed id 15477569)1, 2 Conforti F.L.... Quattrone A. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2 Nagase T.... Ohara O. (2000)
- Identification of a new locus for autosomal recessive Charcot-Marie-Tooth disease with focally folded myelin on chromosome 11p15. (PubMed id 10644431)1, 3 Othmane K.B....Vance J.M. (1999)
- Genome-wide association study identifies two novel loci containing FLNB and SBF2 genes underlying stature variation. (PubMed id 19039035)1, 9 Lei S.F....Deng H.W. (2009)
- Charcot-Marie-Tooth type 4B demyelinating neuropathy: deciphering the role of MTMR phosphatases. (PubMed id 17880751)1, 9 Previtali S.C....Bolino A. (2007)
|
External Searches for SBF2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SBF2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SBF2 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing SBF2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SBF2 | Pharmacogenomics, SNPs, Pathways | | Inherited peripheral neuropathies mutation db | http://www.molgen.ua.ac.be/CMTMutations/ | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/SBF2 |
|
| | |
About This Section
| Patent Information for SBF2 gene:
Search GeneIP for patents involving SBF2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SBF2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | Browse OriGene 29mer shRNA kits in GFP-retroviral vector | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SBF2 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SBF2 | | OriGene 3'-UTR Clone for SBF2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SBF2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SBF2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SBF2 | | OriGene Custom Protein Services for SBF2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SBF2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SBF2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SBF2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SBF2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SBF2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SBF2 |
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| | | | Search Tocris compounds for SBF2 |
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 | | | SBF2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SBF2 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for SBF2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SBF2 |
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