SBDS Gene
protein-coding GIFtS: 62
GCID: GC07M066452
|
|
Shwachman-Bodian-Diamond syndrome
| |
Aliases
for SBDS gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Shwachman-Bodian-Diamond Syndrome1 2 | | FLJ109171 | | SDS1 2 5 | | Ribosome Maturation Protein SBDS2 | | SWDS1 2 | | Shwachman-Bodian-Diamond Syndrome Protein3 | | CGI-971 | | |
Export aliases for SBDS gene to outside databasesPrevious GC identifers: GC07M065093 GC07M065850 GC07M065864 GC07M065896 GC07M066090 GC07M062635 |
Summaries
for SBDS gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SBDS:
This gene encodes a member of a highly conserved protein family that exists from archaea to vertebrates and plants. Theencoded protein may function in RNA metabolism. Mutations within this gene are associated withShwachman-Bodian-Diamond syndrome. An alternative transcript has been described, but its biological nature has notbeen determined. This gene has a closely linked pseudogene that is distally located. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: SBDS_HUMAN, Q9Y3A5Function: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFTUD1, triggers theGTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translationcompetence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellularstress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation
Gene Wiki entry for SBDS
|
Genomic Views
for SBDS gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007933.15 NT_079593.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SBDS gene promoter:
SRF Elk-1 SRF (504 AA) RREB-1 FOXO3 FOXO3b GATA-1 RORalpha1 STAT3 FOXO3a
Other transcription factors
Search SABiosciences Chromatin IP Primers for SBDS
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SBDS |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q11.21 Ensembl cytogenetic band: 7q11.21 HGNC cytogenetic band: 7q11.22SBDS Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07M066452: view genomic region
(about GC identifiers)
Start:
|
66,452,664 bp from pter |
End:
|
66,460,635 bp from pter |
Size:
|
7,972 bases |
Orientation:
|
minus strand |
1 alternative location:
| Chr7-,CRA_TCAG 65,790,252-65,798,150 |
|
Proteins
for SBDS gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SBDS_HUMAN, Q9Y3A5 (See
protein sequence)Recommended Name: Ribosome maturation protein SBDS Size: 250 amino acids; 28764 Da
Subunit: Associates with the 60S ribosomal subunit. Interacts with NPM1, RPA1 and PRKDC. May interact with NIP7
Subcellular location: Cytoplasm. Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, spindle.Note=Primarily detected in the cytoplasm, and at low levels in nucleus and nucleolus (PubMed:19602484 andPubMed:17475909). Detected in the nucleolus during G1 and G2 phase of the cell cycle, and diffusely distributed in thenucleus during S phase. Detected at the mitotic spindle. Colocalizes with the microtubule organizing center duringinterphase (PubMed:19759903)
2 PDB 3D structures from  and Proteopedia  for SBDS:2KDO (3D)
2L9N (3D)
Secondary accessions: A8K0P4 Q96FX0 Q9NV53Explore the universe of human proteins at neXtProt for SBDS: NX_Q9Y3A5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y3A5
SBDS Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_057122.2
ENSEMBL proteins: ENSP00000246868 ENSP00000415618 ENSP00000394586
Human Recombinant Protein Products for SBDS:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
SBDS for ontologies About GeneDecksing
SBDS Antibody Products:
Assay Products for SBDS: |
Protein
Domains /
Families
for SBDS gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SBDS for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9Y3A5ProtoNet protein and cluster: Q9Y3A5 1 Blocks protein family: IPB002140 Protein of unknown function UPF0023
UniProtKB/Swiss-Prot: SBDS_HUMAN, Q9Y3A5Similarity: Belongs to the SDO1/SBDS family |
Function
for SBDS gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: SBDS_HUMAN, Q9Y3A5Function: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFTUD1, triggers theGTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translationcompetence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellularstress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
SBDS for ontologies About GeneDecksing
Phenotypes:
13 MGI mutant phenotypes (inferred from 6 alleles ) (MGI details for Sbds):
SBDS for phenotypes About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SBDS (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SBDS (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SBDS (NM_016038) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SBDS | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SBDS |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SBDS |
|
Pathways & Interactions
for SBDS gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Ribosome biogenesis in eukaryotes | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Kegg Pathway (Kegg details for SBDS):
SBDS for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SBDS
STRING Interaction
Network Preview (showing 5 interactants - click image to see 22)
5/51 Interacting proteins for SBDS (Q9Y3A53 ENSP000002468684) via UniProtKB, MINT, STRING, and/or I2D (see all 51)About this table
Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table
SBDS for ontologies About GeneDecksing
|
Drugs & Compounds
for SBDS gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SBDS
1 HMDB Compound for SBDS About this table
Search CenterWatch for drugs/clinical trials and news about SBDS
|
Transcripts
for SBDS gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SBDS gene: NM_016038.2 Unigene Cluster for SBDS: Shwachman-Bodian-Diamond syndrome Hs.110445 [show with all ESTs]Unigene Representative Sequence: AY1699636 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000246868(uc003tvm.1) ENST00000420420 ENST00000414306 ENST00000496763
ENST00000490953 ENST00000463579
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SBDS (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SBDS (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SBDS (NM_016038) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SBDS | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SBDS |
Additional cDNA sequence: AF151855.1 AK001779.1 AK289609.1 AY169963.1 BC065700.1 15 DOTS entries: DT.100828046 DT.442442 DT.121116345 DT.100828036 DT.100031370 DT.100828026 DT.100828038 DT.100828027 DT.121057685 DT.121058023 DT.91900904 DT.102843941 DT.121057811 DT.121116324 DT.92454584 24/321 AceView cDNA sequences (see all 321): NM_016038 BM505370 BC065700 AA932576 CA448228 CR596032 BF792729 AA564849 AW161209 AI809949 CR626007 BM833373 BP355898 BM126186 AI270663 BM784674 AL550005 AA860575 BF343814 BM141988 AI572774 CR613195 BF844583 AW302566
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for SBDS About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 |
|---|
|
| SP1: | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | | | | | | | | |
ECgene alternative splicing isoforms for SBDS
|
Expression
for SBDS gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SBDS expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGCCATAAC
About this image
See SBDS Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SBDS
SOURCE GeneReport for Unigene cluster: Hs.110445
UniProtKB/Swiss-Prot: SBDS_HUMAN, Q9Y3A5Tissue specificity: Widely expressed
SABiosciences Custom PCR Arrays for SBDS
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SBDS
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SBDS | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SBDS | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SBDS | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SBDS |
Orthologs
for SBDS gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SBDS gene from 9/38 species (see all 38) About this table
ENSEMBL Gene Tree for SBDS (if available)
TreeFam Gene Tree for SBDS (if available) |
Paralogs
for SBDS gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SBDS gene
SBDS for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for SBDS
PGOHUM00000233413
|
Genomic Variants
for SBDS gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SBDS (66452664 - 66460635 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for SBDS
1 CNV: 3683
Human Gene Mutation Database (HGMD): SBDS
Locus Specific Mutation Databases (LSDB): SBDS
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SBDS |
|
Disorders
/ Diseases
for SBDS gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SBDS for disorders About GeneDecksing
OMIM gene information: 607444
OMIM disorders: 260400
UniProtKB/Swiss-Prot: SBDS_HUMAN, Q9Y3A5
Defects in SBDS are the cause of Shwachman-Diamond syndrome (SDS) [MIM:260400]. SDS is an autosomal recessivedisorder characterized by pancreatic exocrine insufficiency, hematologic dysfunction, and skeletal abnormalities
18  diseases for SBDS: About MalaCardsshwachman-diamond syndrome exocrine pancreatic insufficiency common variable immunodeficiency dyskeratosis congenita
type 1 diabetes mellitus metaphyseal dysplasia aplastic anemia batten disease
diabetes mellitus dyskeratosis neutropenia myeloid malignancy
anemia osteoporosis immunodeficiency pancreatitis
malaria leukemia
4 diseases from the University of Copenhagen DISEASES database for SBDS:Exocrine pancreatic insufficiency Neutropenia Metaphyseal dysplasia Autosomal recessive disease 4 Novoseek disease relationships for SBDS gene About this table
GeneTests: SBDS
Shwachman-Diamond Syndrome
Human Genome Epidemiology (HuGE) Navigator: SBDS (3 documents)
Export disorders for SBDS gene to outside databases
|
Publications
for SBDS gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SBDS gene, integrated from 9 sources (see all 67):
(articles sorted by number of sources associating them with SBDS) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Mutations in SBDS are associated with Shwachman-Diamond syndrome. (PubMed id 12496757)1, 2, 3, 9 Boocock G.R.B.... Rommens J.M. (2003)
- The human Shwachman-Diamond syndrome protein, SBDS, associates with ribosomal RNA. (PubMed id 17475909)1, 2, 9 Ganapathi K.A....Shimamura A. (2007)
- SBDS expression and localization at the mitotic spind le in human myeloid progenitors. (PubMed id 19759903)1, 2, 9 Orelio C....Kuijpers T.W. (2009)
- The Shwachman-Diamond SBDS protein localizes to the nucleolus. (PubMed id 15860664)1, 2, 9 Austin K.M....Shimamura A. (2005)
- Structure, dynamics, and RNA interaction analysis of the human SBDS protein. (PubMed id 20053358)1, 2, 9 de Oliveira J.F....Zeri A.C. (2010)
- The Shwachman-Bodian-Diamond syndrome associated protein interacts with HsNip7 and its down-regulation affects gene expression at the transcriptional and translational levels. (PubMed id 17643419)1, 2, 9 Hesling C....Zanchin N.I. (2007)
- Shwachman-Bodian Diamond syndrome is a multi-function al protein implicated in cellular stress responses. (PubMed id 19602484)1, 2 Ball H.L....Myers J.S. (2009)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2 Lai C.H....Lin W. (2000)
|
External Searches for SBDS gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SBDS gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SBDS gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SBDS gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SBDS | Pharmacogenomics, SNPs, Pathways | | ATLAS Chromosomes in Cancer entry for SBDS | Genetics and Cytogenetics in Oncology and Haematology | | SBDSbase | http://bioinf.uta.fi/SBDSbase/ | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/SBDS |
|
| | |
About This Section
| Patent Information for SBDS gene:
Search GeneIP for patents involving SBDS
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SBDS gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for SBDS | | OriGene shRNA RFP for SBDS | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SBDS | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SBDS | | | OriGene Protein Over-expression Lysate for SBDS | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SBDS | | OriGene 3'-UTR Clone for SBDS | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SBDS | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SBDS | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for SBDS | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SBDS | | OriGene Custom Protein Services for SBDS | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SBDS | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SBDS | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SBDS | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SBDS | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SBDS | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SBDS |
| |
 |  |  |  | |
| | | | Search Tocris compounds for SBDS |
| |  |  |  |  | | | | | | Recombinant Protein for SBDS |
|
 |
 |
 |
 | | | SBDS Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SBDS |
|  |  |  |  | | | | Search ThermoFisher Antibodies for SBDS |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SBDS |
| |  | |
|
|
|
