SAYSD1 Gene
protein-coding GIFtS: 39
GCID: GC06M039183
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SAYSVFN motif domain containing 1(Previous name: chromosome 6 open reading frame 64 )
(Previous symbol: C6orf64)
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Aliases
for SAYSD1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| SAYSVFN Motif Domain Containing 11 2 | | C6orf641 2 3 | | FLJ111011 | | Chromosome 6 Open Reading Frame 641 | | SAYSvFN Domain-Containing Protein 12 |
Export aliases for SAYSD1 gene to outside databasesPrevious GC identifers: GC06M039072 GC06M039076 |
Summaries
for SAYSD1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for SAYSD1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007592.15
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for SAYSD1
Other transcription factors
Search SABiosciences Chromatin IP Primers for SAYSD1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SAYSD1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p21.2 Ensembl cytogenetic band: 6p21.2 HGNC cytogenetic band: 6p21.1SAYSD1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06M039183: view genomic region
(about GC identifiers)
Start:
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39,071,840 bp from pter |
End:
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39,082,965 bp from pter |
Size:
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11,126 bases |
Orientation:
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minus strand |
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Proteins
for SAYSD1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SMDC1_HUMAN, Q9NPB0 (See
protein sequence)Recommended Name: SAYSvFN domain-containing protein 1 Size: 183 amino acids; 20163 Da
Subcellular location: Cytoplasmic vesicle membrane; Single-pass membrane protein
Secondary accessions: Q9H0D8Alternative splicing: 2 isoforms: Q9NPB0-1 Q9NPB0-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SAYSD1: NX_Q9NPB0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NPB0
SAYSD1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_060792.1
ENSEMBL proteins: ENSP00000362346 ENSP00000229903
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- | | GO:0030659 | cytoplasmic vesicle membrane |
IEA | -- |
SAYSD1 for ontologies About GeneDecksing
SAYSD1 Antibody Products:
Assay Products for SAYSD1: |
Protein
Domains /
Families
for SAYSD1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SAYSD1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9NPB0ProtoNet protein and cluster: Q9NPB0 |
Function
for SAYSD1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SAYSD1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SAYSD1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for SAYSD1 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SAYSD1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SAYSD1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SAYSD1 |
1 GenomeRNAi human phenotype for SAYSD1:
|
Pathways & Interactions
for SAYSD1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SAYSD1
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
2 Interacting proteins for SAYSD1 (Q9NPB03 ENSP000002299034) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for SAYSD1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SAYSD1
Search CenterWatch for drugs/clinical trials and news about SAYSD1 / SMDC1
|
Transcripts
for SAYSD1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SAYSD1 gene: NM_018322.1 Unigene Cluster for SAYSD1: SAYSVFN motif domain containing 1 Hs.58382 [show with all ESTs]Unigene Representative Sequence: CR6272443 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000373249(uc003oom.2) ENST00000229903(uc003ook.1) ENST00000481599
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SAYSD1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SAYSD1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for SAYSD1 | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SAYSD1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SAYSD1 |
Additional cDNA sequence: AF086405.1 AK001963.1 AK024286.1 AK124992.1 AL136839.1 BC022007.2 CR627244.1 9 DOTS entries: DT.310867 DT.95154284 DT.97769801 DT.310868 DT.92027547 DT.121348096 DT.121348002 DT.100778690 DT.91820002 24/152 AceView cDNA sequences (see all 152): BQ927151 CB240756 AA677121 BM681124 BE856483 CB853269 CR621024 AI816016 BX094530 AI361955 BP375658 BU631592 BU623927 BE467312 CR593115 AI624834 CK905050 AI249699 BG722325 AF086405 BM727697 BM843882 CB994038 BU858092
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for SAYSD1 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | · | 2c | · | 2d | · | 2e | ^ | 3a | · | 3b |
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| SP1: | | | | | | | - | | - | | - | | - | | - | | | | | | |
| SP2: | | | | | | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | - | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SAYSD1
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Expression
for SAYSD1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SAYSD1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See SAYSD1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SAYSD1
SOURCE GeneReport for Unigene cluster: Hs.58382
SABiosciences Custom PCR Arrays for SAYSD1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SAYSD1
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat SAYSD1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SAYSD1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SAYSD1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SAYSD1 |
Orthologs
for SAYSD1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SAYSD1 gene from 7/18 species (see all 18) About this table
ENSEMBL Gene Tree for SAYSD1 (if available)
TreeFam Gene Tree for SAYSD1 (if available) |
Paralogs
for SAYSD1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for SAYSD1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SAYSD1 (39071840 - 39082965 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SAYSD1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SAYSD1 |
|
Disorders
/ Diseases
for SAYSD1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for SAYSD1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SAYSD1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with SAYSD1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
- Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy. (PubMed id 22361696)2 Stadler C.... Lundberg E. (2012)
- Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for SAYSD1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing SAYSD1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SAYSD1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SAYSD1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SAYSD1 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for SAYSD1 gene:
Search GeneIP for patents involving SAYSD1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SAYSD1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 |
| | |  | OriGene Antibodies for SAYSD1 | | OriGene shRNA RFP for SAYSD1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SAYSD1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SAYSD1 | | | OriGene Protein Over-expression Lysate for SAYSD1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SAYSD1 | | OriGene 3'-UTR Clone for SAYSD1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SAYSD1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SAYSD1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for SAYSD1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SAYSD1 | | OriGene Custom Protein Services for SAYSD1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SAYSD1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SAYSD1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SAYSD1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SAYSD1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SAYSD1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SAYSD1 |
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| | | | Search Tocris compounds for SAYSD1 |
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 | | | SAYSD1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SAYSD1 |
|  |  |  | | | | Search ThermoFisher Antibodies for SAYSD1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SAYSD1 |
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