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Aliases for SAYSD1 Gene

Aliases for SAYSD1 Gene

  • SAYSVFN Motif Domain Containing 1 2 3 5
  • C6orf64 3 4
  • Chromosome 6 Open Reading Frame 64 2

External Ids for SAYSD1 Gene

Previous HGNC Symbols for SAYSD1 Gene

  • C6orf64

Previous GeneCards Identifiers for SAYSD1 Gene

  • GC06M039072
  • GC06M039076
  • GC06M039183
  • GC06M039215
  • GC06M039259
  • GC06M039253
  • GC06M039331

Summaries for SAYSD1 Gene

GeneCards Summary for SAYSD1 Gene

SAYSD1 (SAYSVFN Motif Domain Containing 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SAYSD1 Gene

Genomics for SAYSD1 Gene

Regulatory Elements for SAYSD1 Gene

Enhancers for SAYSD1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around SAYSD1 on UCSC Golden Path with GeneCards custom track

Promoters for SAYSD1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around SAYSD1 on UCSC Golden Path with GeneCards custom track

Genomic Location for SAYSD1 Gene

39,104,063 bp from pter
39,115,189 bp from pter
11,127 bases
Minus strand

Genomic View for SAYSD1 Gene

Genes around SAYSD1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SAYSD1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SAYSD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SAYSD1 Gene

Proteins for SAYSD1 Gene

  • Protein details for SAYSD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    SAYSvFN domain-containing protein 1
    Protein Accession:
    Secondary Accessions:
    • Q9H0D8

    Protein attributes for SAYSD1 Gene

    183 amino acids
    Molecular mass:
    20163 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SAYSD1 Gene


neXtProt entry for SAYSD1 Gene

Proteomics data for SAYSD1 Gene at MOPED

Post-translational modifications for SAYSD1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SAYSD1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SAYSD1 Gene

Domains & Families for SAYSD1 Gene

Protein Domains for SAYSD1 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SAYSD1: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SAYSD1 Gene

Function for SAYSD1 Gene

Phenotypes for SAYSD1 Gene

genes like me logo Genes that share phenotypes with SAYSD1: view

Animal Model Products

CRISPR Products

miRNA for SAYSD1 Gene

miRTarBase miRNAs that target SAYSD1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SAYSD1 Gene

Localization for SAYSD1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SAYSD1 Gene

Cytoplasmic vesicle membrane; Single-pass membrane protein.

Subcellular locations from

Jensen Localization Image for SAYSD1 Gene COMPARTMENTS Subcellular localization image for SAYSD1 gene
Compartment Confidence
mitochondrion 2
peroxisome 2
cytosol 1
endoplasmic reticulum 1
extracellular 1
nucleus 1

Gene Ontology (GO) - Cellular Components for SAYSD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
GO:0043231 intracellular membrane-bounded organelle IDA --
genes like me logo Genes that share ontologies with SAYSD1: view

Pathways & Interactions for SAYSD1 Gene

SuperPathways for SAYSD1 Gene

No Data Available

Interacting Proteins for SAYSD1 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000229903 Q9NPB0-SMDC1_HUMAN for SAYSD1 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for SAYSD1 Gene


No data available for Pathways by source and SIGNOR curated interactions for SAYSD1 Gene

Drugs & Compounds for SAYSD1 Gene

No Compound Related Data Available

Transcripts for SAYSD1 Gene

Unigene Clusters for SAYSD1 Gene

SAYSVFN motif domain containing 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SAYSD1 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c · 2d · 2e ^ 3a · 3b
SP1: - - - - -
SP2: -
SP3: - -

Relevant External Links for SAYSD1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SAYSD1 Gene

mRNA expression in normal human tissues for SAYSD1 Gene

mRNA differential expression in normal tissues according to GTEx for SAYSD1 Gene

This gene is overexpressed in Testis (x6.5).

Protein differential expression in normal tissues from HIPED for SAYSD1 Gene

This gene is overexpressed in Bone (48.8) and Fetal ovary (7.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for SAYSD1 Gene

SOURCE GeneReport for Unigene cluster for SAYSD1 Gene Hs.58382

genes like me logo Genes that share expression patterns with SAYSD1: view

Protein tissue co-expression partners for SAYSD1 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for SAYSD1 Gene

Orthologs for SAYSD1 Gene

This gene was present in the common ancestor of animals.

Orthologs for SAYSD1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SAYSD1 35
  • 78.51 (n)
  • 77.05 (a)
  • 73 (a)
(Canis familiaris)
Mammalia SAYSD1 35
  • 87.25 (n)
  • 85.25 (a)
  • 80 (a)
(Mus musculus)
Mammalia Saysd1 35
  • 79.92 (n)
  • 78.41 (a)
Saysd1 16
Saysd1 36
  • 74 (a)
(Pan troglodytes)
Mammalia SAYSD1 35
  • 99.27 (n)
  • 98.91 (a)
  • 99 (a)
(Monodelphis domestica)
Mammalia SAYSD1 36
  • 86 (a)
(Ornithorhynchus anatinus)
Mammalia SAYSD1 36
  • 84 (a)
(Gallus gallus)
Aves SAYSD1 36
  • 49 (a)
(Anolis carolinensis)
Reptilia SAYSD1 36
  • 56 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia saysd1 35
  • 54.8 (n)
  • 53.11 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.30665 35
(Danio rerio)
Actinopterygii SAYSD1 36
  • 44 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG13663 36
  • 28 (a)
(Caenorhabditis elegans)
Secernentea C13F10.5 36
  • 31 (a)
Species with no ortholog for SAYSD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SAYSD1 Gene

Gene Tree for SAYSD1 (if available)
Gene Tree for SAYSD1 (if available)

Paralogs for SAYSD1 Gene

No data available for Paralogs for SAYSD1 Gene

Variants for SAYSD1 Gene

Sequence variations from dbSNP and Humsavar for SAYSD1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs6902597 -- 39,112,174(+) ACCTC(A/G)AAAGG intron-variant, utr-variant-5-prime
rs3840 -- 39,105,222(-) GGGTC(C/T)GACGC utr-variant-3-prime
rs7696 -- 39,104,905(+) TAAAG(A/G)TATTT utr-variant-3-prime
rs10023 -- 39,104,258(-) TGATA(C/T)GTGTT utr-variant-3-prime
rs6933717 -- 39,110,345(+) ATTTG(G/T)CCTGT intron-variant, utr-variant-5-prime

Variation tolerance for SAYSD1 Gene

Residual Variation Intolerance Score: 47.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.66; 31.71% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for SAYSD1 Gene

Disorders for SAYSD1 Gene

Relevant External Links for SAYSD1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SAYSD1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SAYSD1 Gene

Publications for SAYSD1 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  3. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  5. A germline-specific class of small RNAs binds mammalian Piwi proteins. (PMID: 16751776) Girard A. … Carmell M.A. (Nature 2006) 3

Products for SAYSD1 Gene

Sources for SAYSD1 Gene