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Aliases for SAXO2 Gene

Aliases for SAXO2 Gene

  • Stabilizer Of Axonemal Microtubules 2 2 3
  • Family With Sequence Similarity 154, Member B 2 3
  • FAM154B 3 4
  • Protein FAM154B 3

External Ids for SAXO2 Gene

Previous HGNC Symbols for SAXO2 Gene

  • FAM154B

Summaries for SAXO2 Gene

GeneCards Summary for SAXO2 Gene

SAXO2 (Stabilizer Of Axonemal Microtubules 2) is a Protein Coding gene. An important paralog of this gene is SAXO1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SAXO2 Gene

Genomics for SAXO2 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SAXO2 Gene

82,262,810 bp from pter
82,284,930 bp from pter
22,121 bases
Plus strand

Genomic View for SAXO2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SAXO2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SAXO2 Gene

No data available for Regulatory Elements for SAXO2 Gene

Proteins for SAXO2 Gene

  • Protein details for SAXO2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Stabilizer of axonemal microtubules 2
    Protein Accession:
    Secondary Accessions:
    • B4E2M2

    Protein attributes for SAXO2 Gene

    398 amino acids
    Molecular mass:
    45933 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SAXO2 Gene


neXtProt entry for SAXO2 Gene

Proteomics data for SAXO2 Gene at MOPED

Post-translational modifications for SAXO2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SAXO2 Gene

No data available for DME Specific Peptides for SAXO2 Gene

Domains & Families for SAXO2 Gene

Protein Domains for SAXO2 Gene


Suggested Antigen Peptide Sequences for SAXO2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM154 family.
  • Belongs to the FAM154 family.
genes like me logo Genes that share domains with SAXO2: view

No data available for Gene Families for SAXO2 Gene

Function for SAXO2 Gene

Phenotypes for SAXO2 Gene

GenomeRNAi human phenotypes for SAXO2:
genes like me logo Genes that share phenotypes with SAXO2: view

miRNA for SAXO2 Gene

miRTarBase miRNAs that target SAXO2

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for SAXO2 Gene

Localization for SAXO2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SAXO2 Gene

Pathways & Interactions for SAXO2 Gene

SuperPathways for SAXO2 Gene

No Data Available

Interacting Proteins for SAXO2 Gene

Gene Ontology (GO) - Biological Process for SAXO2 Gene


No data available for Pathways by source and SIGNOR curated interactions for SAXO2 Gene

Drugs & Compounds for SAXO2 Gene

No Compound Related Data Available

Transcripts for SAXO2 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for SAXO2 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7
SP1: - - -
SP2: - -
SP3: -
SP4: - -

Relevant External Links for SAXO2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SAXO2 Gene

mRNA expression in normal human tissues for SAXO2 Gene

genes like me logo Genes that share expression patterns with SAXO2: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SAXO2 Gene

Orthologs for SAXO2 Gene

This gene was present in the common ancestor of animals.

Orthologs for SAXO2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM154B 35
  • 79.91 (n)
  • 75.58 (a)
FAM154B 36
  • 64 (a)
(Canis familiaris)
Mammalia FAM154B 35
  • 87.1 (n)
  • 84.16 (a)
FAM154B 36
  • 84 (a)
(Mus musculus)
Mammalia Fam154b 35
  • 86.68 (n)
  • 83.97 (a)
Fam154b 16
Fam154b 36
  • 84 (a)
(Pan troglodytes)
Mammalia FAM154B 35
  • 98.58 (n)
  • 97.74 (a)
FAM154B 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Fam154b 35
  • 86.6 (n)
  • 82.95 (a)
(Monodelphis domestica)
Mammalia FAM154B 36
  • 48 (a)
(Ornithorhynchus anatinus)
Mammalia FAM154B 36
  • 24 (a)
(Gallus gallus)
Aves FAM154B 35
  • 67.28 (n)
  • 58.16 (a)
FAM154B 36
  • 47 (a)
(Anolis carolinensis)
Reptilia FAM154B 36
  • 43 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam154b 35
  • 65.54 (n)
  • 58.18 (a)
(Danio rerio)
Actinopterygii Dr.15468 35
fam154b 35
  • 55.44 (n)
  • 48.13 (a)
fam154b 36
  • 39 (a)
(Caenorhabditis elegans)
Secernentea T08G11.3 36
  • 14 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 32 (a)
-- 36
  • 32 (a)
Species with no ortholog for SAXO2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SAXO2 Gene

Gene Tree for SAXO2 (if available)
Gene Tree for SAXO2 (if available)

Paralogs for SAXO2 Gene

Paralogs for SAXO2 Gene Pseudogenes for SAXO2 Gene

genes like me logo Genes that share paralogs with SAXO2: view

Variants for SAXO2 Gene

Sequence variations from dbSNP and Humsavar for SAXO2 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs1846910 -- 82,279,439(+) TTGAT(A/G)TGTTA intron-variant
rs1966026 -- 82,265,202(+) gtggc(A/C)ggatc intron-variant
rs1966027 -- 82,265,203(+) tggca(C/G)gatct intron-variant
rs1976416 -- 82,265,280(+) ggact(A/G)caggg intron-variant
rs3858954 -- 82,265,693(+) TTAAA(C/G)CCAAG intron-variant

Variation tolerance for SAXO2 Gene

Residual Variation Intolerance Score: 92.31% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 20.17; 99.04% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SAXO2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SAXO2 Gene

Disorders for SAXO2 Gene

Relevant External Links for SAXO2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with SAXO2: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SAXO2 Gene

Publications for SAXO2 Gene

  1. Human FAM154A (SAXO1) is a microtubule-stabilizing protein specific to cilia and related structures. (PMID: 25673876) Dacheux D. … Bonhivers M. (J. Cell. Sci. 2015) 2 67
  2. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 67
  3. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody M.C. … Nusbaum C. (Nature 2006) 67
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for SAXO2 Gene

Sources for SAXO2 Gene

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