Aliases for SAXO2 Gene
Aliases for SAXO2 Gene
External Ids for SAXO2 Gene
- HGNC: 33727
- Entrez Gene: 283726
- Ensembl: ENSG00000188659
- UniProtKB: Q658L1
Previous HGNC Symbols for SAXO2 Gene
- FAM154B
Summaries for SAXO2 Gene
GeneCards Summary for SAXO2 Gene
SAXO2 (Stabilizer Of Axonemal Microtubules 2) is a Protein Coding gene. An important paralog of this gene is SAXO1.
No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SAXO2 Gene
Genomics for SAXO2 Gene
Regulatory Elements for SAXO2 Gene
Enhancers for SAXO2 Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around SAXO2 on UCSC Golden Path with GeneCards custom track
Promoters for SAXO2 Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|
ENSRs around SAXO2 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for SAXO2 Gene
- Chromosome:
- 15
- Start:
- 82,262,810 bp from pter
- End:
- 82,284,930 bp from pter
- Size:
- 22,121 bases
- Orientation:
- Plus strand
Genomic View for SAXO2 Gene
Genes around SAXO2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 15q25.2 by Ensembl
- 15q25.2 by Entrez Gene
- 15q25.2 by HGNC
SAXO2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SAXO2 Gene
Proteins for SAXO2 Gene
-
Protein details for SAXO2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q658L1-SAXO2_HUMAN
- Recommended name:
- Stabilizer of axonemal microtubules 2
- Protein Accession:
- Q658L1
- B4E2M2
Protein attributes for SAXO2 Gene
- Size:
- 398 amino acids
- Molecular mass:
- 45933 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for SAXO2 Gene
Other Protein References for SAXO2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Protein Products
-
OriGene Purified Proteins for SAXO2
- Search Origene for MassSpec and Protein Over-expression Lysates for SAXO2
- Origene Custom Protein Services for SAXO2
- Search GeneTex for Proteins for SAXO2
Assay Products
No data available for DME Specific Peptides for SAXO2 Gene
Domains & Families for SAXO2 Gene
Protein Domains for SAXO2 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for SAXO2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q658L1- Family:
-
- Belongs to the FAM154 family.
No data available for Gene Families for SAXO2 Gene
Function for SAXO2 Gene
Phenotypes for SAXO2 Gene
- GenomeRNAi human phenotypes for SAXO2:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for SAXO2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for SAXO2 gene
- Search ViGene Biosciences for SAXO2
CRISPR Products
-
OriGene CRISPR knockouts for SAXO2
- GenScript: Design CRISPR guide RNA sequences for SAXO2
miRNA Products
- Search ViGene Biosciences for SAXO2
Inhibitory RNA Products
- Origene RNAi, shRNA, rat_shrna, and siRNA products in human, mouse, rat for SAXO2
- Browse OriGene Inhibitory RNA Products For SAXO2
-
ViGene Biosciences ready-to-package AAV shRNAs for SAXO2 gene
Clone Products
- OriGene ORF clones in human,rat for SAXO2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for SAXO2 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for SAXO2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for SAXO2 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SAXO2 Gene
Localization for SAXO2 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SAXO2 Gene
More details on SuperPathways for SAXO2Transcripts for SAXO2 Gene
mRNA/cDNA for SAXO2 Gene
- (1) REFSEQ mRNAs :
- (20) Selected AceView cDNA sequences:
- (8) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for SAXO2
- GenScript: Design CRISPR guide RNA sequences for SAXO2
miRNA Products
- Search ViGene Biosciences for SAXO2
Inhibitory RNA Products
- Origene RNAi, shRNA, rat_shrna, and siRNA products in human, mouse, rat for SAXO2
- Browse OriGene Inhibitory RNA Products For SAXO2
-
ViGene Biosciences ready-to-package AAV shRNAs for SAXO2 gene
Clone Products
- OriGene ORF clones in human,rat for SAXO2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
Flow Cytometry Products
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||
| SP2: | - | - | |||||||||||||||
| SP3: | - | ||||||||||||||||
| SP4: | - | - |
Expression for SAXO2 Gene
Primer Products
-
OriGene qPCR primer pairs for SAXO2
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SAXO2 Gene
Orthologs for SAXO2 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | FAM154B 35 |
|
||
| FAM154B 36 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | FAM154B 35 |
|
||
| FAM154B 36 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | Fam154b 35 |
|
||
| Saxo2 16 |
|
||||
| Fam154b 36 |
|
OneToOne | |||
| chimpanzee (Pan troglodytes) |
Mammalia | FAM154B 35 |
|
||
| FAM154B 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | Fam154b 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | FAM154B 36 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | FAM154B 36 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | FAM154B 35 |
|
||
| FAM154B 36 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | FAM154B 36 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | fam154b 35 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | Dr.15468 35 |
|
||
| fam154b 35 |
|
||||
| fam154b 36 |
|
OneToOne | |||
| worm (Caenorhabditis elegans) |
Secernentea | T08G11.3 36 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 36 |
|
ManyToMany | |
| -- 36 |
|
ManyToMany |
- Species with no ortholog for SAXO2:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for SAXO2 Gene
Pseudogenes.org Pseudogenes for SAXO2 Gene
Variants for SAXO2 Gene
| SNP ID | Clin | Chr 15 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| VAR_039359 | - | ||||
| rs16973457 | - | 82,271,650(+) | TGTGC(C/T)AGAAG | reference, missense | |
| rs11630197 | - | 82,282,538(+) | AACCA(C/T)GGGAA | reference, missense | |
| rs11856677 | -- | 82,266,110(+) | ataca(A/G)taaca | intron-variant | |
| rs12372925 | -- | 82,270,165(+) | ctaag(C/T)tgtgg | intron-variant |
Residual Variation Intolerance Score:
92.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
20.17;
99.04% of all genes are more intolerant (likely to be disease-causing)
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for SAXO2 Gene
Disorders for SAXO2 Gene
Relevant External Links for SAXO2
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- SAXO2
No disorders were found for SAXO2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SAXO2 Gene
Publications for SAXO2 Gene
- Human FAM154A (SAXO1) is a microtubule-stabilizing protein specific to cilia and related structures. (PMID: 25673876) Dacheux D. … Bonhivers M. (J. Cell. Sci. 2015) 2 3 67
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
Products for SAXO2 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for SAXO2
- Search Origene for MassSpec and Protein Over-expression Lysates for SAXO2
- Origene Custom Protein Services for SAXO2
- Origene siRNA, shRNA, rat_shrna, and RNAi products in human, mouse, rat for SAXO2
- Browse OriGene Inhibitory RNA Products For SAXO2
- OriGene qPCR primer pairs for SAXO2
- OriGene CRISPR knockouts for SAXO2
- OriGene ORF clones in human,rat for SAXO2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: Next-day shipping cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for SAXO2
- GenScript Custom Assay Services for SAXO2
- GenScript Custom overexpressing Cell Line Services for SAXO2
- GenScript: Design CRISPR guide RNA sequences for SAXO2
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for SAXO2
- Novus Biologicals Antibodies for SAXO2
- Novus Biologicals proteins and lysates for SAXO2
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ViGene Biosciences adenoviral particle packaged cDNA for SAXO2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for SAXO2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for SAXO2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for SAXO2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for SAXO2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for SAXO2 gene
- Search ViGene Biosciences for SAXO2
- Search ViGene Biosciences for SAXO2
Sources for SAXO2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
- (111) Addgene
- (112) Advanced Cell Diagnostics
- (113) antibodies-online
- (114) CYP
- (115) NONCODE
- (116) SwitchGear Genomics
- (117) TreeFam
- (118) PathCards
- (119) GeneReviews
- (120) GeneTex
- (121) Taconic Biosciences
- (122) GTEx
- (123) ProteomicsDB
- (124) SCBT
- (125) DGIdb
- (126) ClinicalTrials
- (127) FDA Approved Drugs
- (128) RVIS
- (129) SIGNOR
- (130) diseasecard
- (131) NIH Rare Diseases
- (132) Orphanet
- (133) UMLS
- (134) GTR
- (135) Disease Ontology
- (136) Genetics Home Reference
- (137) MeSH
- (138) MedlinePlus
- (139) CDC
- (140) NINDS
- (141) NCBI Bookshelf
- (142) ClinVar
- (143) Gene Damage Index
- (144) ViGene Biosciences
- (145) HPO
- (146) UDN
- (147) VISTA
- (148) FANTOM5
- (149) ENCODE
- (150) ProSci
- (151) Horizon