Free for academic non-profit institutions. Other users need a Commercial license

Aliases for SATL1 Gene

Aliases for SATL1 Gene

  • Spermidine/Spermine N1-Acetyl Transferase Like 1 2 3 5
  • EC 2.3.1.- 4

External Ids for SATL1 Gene

Previous GeneCards Identifiers for SATL1 Gene

  • GC0XM083120
  • GC0XM084153
  • GC0XM084347
  • GC0XM077920

Summaries for SATL1 Gene

GeneCards Summary for SATL1 Gene

SATL1 (Spermidine/Spermine N1-Acetyl Transferase Like 1) is a Protein Coding gene. GO annotations related to this gene include N-acetyltransferase activity. An important paralog of this gene is SAT1.

Additional gene information for SATL1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SATL1 Gene

Genomics for SATL1 Gene

Regulatory Elements for SATL1 Gene

Enhancers for SATL1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XH085003 1 ENCODE 16.5 +112.0 111994 1 FOXA2 PKNOX1 ARID4B SIN3A FEZF1 DMAP1 YY1 ZNF121 KLF7 ATF7 SATL1 APOOL
GH0XH085051 0.9 Ensembl ENCODE 16.3 +63.4 63381 2 SCRT1 CTCF JUN CEBPB EP300 RAD21 JUND POLR2A SMC3 FOS SATL1 APOOL
GH0XH085111 0.6 ENCODE 18.9 +3.8 3815 1 ELF3 CTCF NFIC NFIA BHLHE40 NR2C1 SATL1 APOOL
GH0XH085220 0.3 FANTOM5 9.1 -104.5 -104504 0 SATL1 LOC101928128 LOC105369163
GH0XH085188 0.3 FANTOM5 8.6 -72.4 -72390 0 SATL1 ZNF711 ENSG00000276391 ENSG00000283446
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SATL1 on UCSC Golden Path with GeneCards custom track

Genomic Location for SATL1 Gene

85,092,286 bp from pter
85,116,178 bp from pter
23,893 bases
Minus strand

Genomic View for SATL1 Gene

Genes around SATL1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SATL1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SATL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SATL1 Gene

Proteins for SATL1 Gene

  • Protein details for SATL1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Spermidine/spermine N(1)-acetyltransferase-like protein 1
    Protein Accession:
    Secondary Accessions:
    • A0AVK7
    • E9PB72
    • Q5H8V9

    Protein attributes for SATL1 Gene

    508 amino acids
    Molecular mass:
    55833 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SATL1 Gene


neXtProt entry for SATL1 Gene

Post-translational modifications for SATL1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SATL1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SATL1 Gene

Domains & Families for SATL1 Gene

Gene Families for SATL1 Gene

Protein Domains for SATL1 Gene

Suggested Antigen Peptide Sequences for SATL1 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the acetyltransferase family.
  • Belongs to the acetyltransferase family.
genes like me logo Genes that share domains with SATL1: view

Function for SATL1 Gene

Enzyme Numbers (IUBMB) for SATL1 Gene

Gene Ontology (GO) - Molecular Function for SATL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004145 diamine N-acetyltransferase activity IBA --
GO:0008080 N-acetyltransferase activity IEA --
GO:0016740 transferase activity IEA --
GO:0016746 transferase activity, transferring acyl groups IEA --
GO:0019809 spermidine binding IBA --
genes like me logo Genes that share ontologies with SATL1: view
genes like me logo Genes that share phenotypes with SATL1: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for SATL1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SATL1 Gene

Localization for SATL1 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SATL1 gene
Compartment Confidence
cytosol 4
nucleus 3

Gene Ontology (GO) - Cellular Components for SATL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005829 cytosol IBA --
genes like me logo Genes that share ontologies with SATL1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for SATL1 Gene

Pathways & Interactions for SATL1 Gene

SuperPathways for SATL1 Gene

No Data Available

Interacting Proteins for SATL1 Gene

Gene Ontology (GO) - Biological Process for SATL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0032918 spermidine acetylation IBA --
GO:0046208 spermine catabolic process IBA --
genes like me logo Genes that share ontologies with SATL1: view

No data available for Pathways by source and SIGNOR curated interactions for SATL1 Gene

Drugs & Compounds for SATL1 Gene

No Compound Related Data Available

Transcripts for SATL1 Gene

mRNA/cDNA for SATL1 Gene

(3) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SATL1 Gene

Spermidine/spermine N1-acetyl transferase-like 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for SATL1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for SATL1 Gene

No ASD Table

Relevant External Links for SATL1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SATL1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SATL1 Gene

NURSA nuclear receptor signaling pathways regulating expression of SATL1 Gene:


SOURCE GeneReport for Unigene cluster for SATL1 Gene:

genes like me logo Genes that share expression patterns with SATL1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SATL1 Gene

Orthologs for SATL1 Gene

This gene was present in the common ancestor of animals.

Orthologs for SATL1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SATL1 34
  • 97 (a)
(Bos Taurus)
Mammalia SATL1 33 34
  • 89.67 (n)
(Canis familiaris)
Mammalia LOC491992 33
  • 75 (n)
SATL1 34
  • 40 (a)
(Rattus norvegicus)
Mammalia Satl1 33
  • 60.48 (n)
(Mus musculus)
Mammalia Satl1 33 16 34
  • 59.33 (n)
(Monodelphis domestica)
Mammalia SATL1 34
  • 31 (a)
(Ornithorhynchus anatinus)
Mammalia SATL1 34
  • 30 (a)
(Anolis carolinensis)
Reptilia SATL1 34
  • 35 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100488114 33
  • 59.03 (n)
(Danio rerio)
Actinopterygii CR318653.1 34
  • 23 (a)
sat2a 34
  • 21 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG4210 34
  • 17 (a)
(Caenorhabditis elegans)
Secernentea D2023.4 34
  • 16 (a)
Species where no ortholog for SATL1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SATL1 Gene

Gene Tree for SATL1 (if available)
Gene Tree for SATL1 (if available)

Paralogs for SATL1 Gene

Paralogs for SATL1 Gene

(4) SIMAP similar genes for SATL1 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with SATL1: view

Variants for SATL1 Gene

Sequence variations from dbSNP and Humsavar for SATL1 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs1000048388 -- 85,109,783(+) GCGGG(G/T)GGATG intron-variant, upstream-variant-2KB
rs1000195782 -- 85,117,634(+) GAGCC(A/G)GACTG upstream-variant-2KB
rs1000274751 -- 85,112,037(+) TTAGA(C/G)CAGGA intron-variant
rs1000383828 -- 85,100,038(+) CCATC(C/T)CTACT intron-variant
rs1000484534 -- 85,117,064(+) AGTAG(C/G)CCACT upstream-variant-2KB

Variation tolerance for SATL1 Gene

Residual Variation Intolerance Score: 99.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.65; 31.60% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SATL1 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SATL1 Gene

Disorders for SATL1 Gene

Relevant External Links for SATL1

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SATL1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SATL1 Gene

Publications for SATL1 Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross MT … Bentley DR (Nature 2005) 3 4 60
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 60
  4. Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data. (PMID: 17362836) Schymick JC … Traynor BJ (The Lancet. Neurology 2007) 45 60

Products for SATL1 Gene

Sources for SATL1 Gene

Loading form....