SARS2 Gene
protein-coding GIFtS: 59
GCID: GC19M039405
|
|
seryl-tRNA synthetase 2, mitochondrial(Previous names: serine-tRNA ligase, mitochondrial, seryl-tRNA synthetase...) (Previous symbol: SARSM)
| |
Aliases for SARS2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Seryl-TRNA Synthetase 2, Mitochondrial1 2 | | SerRS2 3 | | SARSM1 2 3 | | EC 6.1.1.113 8 | | SerRSmt1 2 3 | | FLJ204501 | | SARS1 2 | | Seryl-TRNA Synthetase 21 | | SERS1 2 | | Mitochondrial Seryl-TRNA Synthetase2 | | SYS1 2 | | Serine TRNA Ligase 2, Mitochondrial2 | | MtSerRS1 | | Serine--TRNA Ligase, Mitochondrial2 | | Serine-TRNA Ligase, Mitochondrial1 2 | | Seryl-TRNA Synthetase, Mitochondrial2 | | Seryl-TRNA(Ser/Sec) Synthetase2 3 | | Seryl-TRNA Synthetase3 |
Export aliases for SARS2 gene to outside databasesPrevious GC identifers: GC19M040018 GC19M039797 GC19M044081 GC19M044097 |
Summaries for SARS2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for SARS2: This gene encodes the mitochondrial seryl-tRNA synthethase precursor, a member of the class II tRNA synthetase family.The mature enzyme catalyzes the ligation of Serine to tRNA(Ser) and participates in the biosynthesis ofselenocysteinyl-tRNA(sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalyticdomain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by abidirectional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are withinthe critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to this disease. Multipletranscript variants encoding different isoforms have been identified for this gene. (provided by RefSeq, Mar 2009) UniProtKB/Swiss-Prot: SYSM_HUMAN, Q9NP81Function: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to formthe misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) Gene Wiki entry for SARS2
|
Genomic Views for SARS2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the SARS2 gene promoter: AhR AML1a ATF-2 p300 Arnt CRE-BP1 POU2F1 POU2F1a SEF-1 (1) Other transcription factors
Search SABiosciences Chromatin IP Primers for SARS2
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SARS2 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.2 Ensembl cytogenetic band: 19q13.2 HGNC cytogenetic band: 19q13.2SARS2 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M039405: view genomic region
(about GC identifiers)
Start:
|
39,405,904 bp from pter |
End:
|
39,466,380 bp from pter |
Size:
|
60,477 bases |
Orientation:
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minus strand |
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Proteins for SARS2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: SYSM_HUMAN, Q9NP81 (See
protein sequence)Recommended Name: Serine--tRNA ligase, mitochondrial precursor Size: 518 amino acids; 58283 Da
Subunit: Homodimer. The tRNA molecule binds across the dimer (By similarity)
Subcellular location: Mitochondrion matrix (By similarity)
Sequence caution: Sequence=AAH01020.2; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: A6NHW7 B4DE10 Q9BVP3Alternative splicing: 2 isoforms: Q9NP81-1 Q9NP81-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SARS2: NX_Q9NP81
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NP81 2 DME Specific Peptides for SARS2 (Q9NP81)
SARS2 Protein expression data from MOPED and PaxDb: About this image 
 REFSEQ proteins (2 alternative transcripts):
NP_001139373.1 NP_060297.1 ENSEMBL proteins: ENSP00000399330 ENSP00000406754 ENSP00000221431 ENSP00000414954 ENSP00000292852 Reactome Protein details: Q9NP81 Human Recombinant Protein Products for SARS2:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
SARS2 for ontologies About GeneDecksing
SARS2 Antibody Products: Assay Products for SARS2: |
Protein
Domains / Families for SARS2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SARS2 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9NP81ProtoNet protein and cluster: Q9NP81 1 Blocks protein family: IPB002317 Seryl-tRNA SYNTHETASE signature
UniProtKB/Swiss-Prot: SYSM_HUMAN, Q9NP81Domain: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding(By similarity)Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily |
Function for SARS2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Molecular Function: UniProtKB/Swiss-Prot Summary: SYSM_HUMAN, Q9NP81Function: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to formthe misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)Catalytic activity: ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser)Catalytic activity: ATP + L-serine + tRNA(Sec) = AMP + diphosphate + L-seryl-tRNA(Sec) Enzyme Number (IUBMB): EC 6.1.1.111 2
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
SARS2 for ontologies About GeneDecksing
Animal Models:
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SARS2 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SARS2 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): SARS2 (NM_017827) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SARS2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SARS2  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SARS2 |
|
Pathways & Interactions for SARS2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | tRNA Aminoacylation | | | 2 | Selenium Metabolism and Selenoproteins | | | 3 | Generic Transcription Pathway | |
Pathway sources See GeneCards unified pathways Show all pathways
1 BioSystems Pathway for SARS2 
3
Reactome Pathways for SARS2
1
Kegg Pathway (Kegg details for SARS2): UniProtKB/Swiss-Prot: SYSM_HUMAN, Q9NP81Pathway: Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine andtRNA(Sec): step 1/1
SARS2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SARS2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/353 Interacting proteins for SARS2 (Q9NP812, 3 ENSP000002214314) via UniProtKB, MINT, STRING, and/or I2D (see all 353) About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
SARS2 for ontologies About GeneDecksing
|
Drugs & Compounds for SARS2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for SARS2
5 HMDB Compounds for SARS2 About this table Search CenterWatch for drugs/clinical trials and news about SARS2 / SYSM 
|
Transcripts for SARS2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for SARS2 gene (2 alternative transcripts): NM_001145901.1 NM_017827.3 Unigene Cluster for SARS2: Seryl-tRNA synthetase 2, mitochondrial Hs.709416 [show with all ESTs]Unigene Representative Sequence: NM_0011459015 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000448145(uc010xuq.1) ENST00000430193(uc010xup.1 uc010xus.1) ENST00000221431(uc002ojz.2 uc002oka.2 uc010xur.1) ENST00000455102 ENST00000292852(uc002okf.1 uc002okg.1)
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SARS2 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SARS2 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): SARS2 (NM_017827) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SARS2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SARS2  |
Additional cDNA sequence: AB029948.1 AK000457.1 AK098522.1 AK293414.1 AK296170.1 BC001020.2 BC042912.1 12 DOTS entries: DT.109655 DT.100778004 DT.97845416 DT.95070365 DT.100778008 DT.95070364 DT.121448218 DT.100641924 DT.100807435 DT.100839528 DT.95120726 DT.40238903 24/175 AceView cDNA sequences (see all 175): BQ070460 BG250432 BQ054152 AL521384 CR599609 BM788801 AL523540 BQ227012 BX098767 BC042912 AI392724 CR611000 BE905396 BM791903 AL559404 BF002302 BI860987 AA336553 AI590551 BU196970 BM912108 BQ690710 BU617807 CA488180 GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for SARS2 (see all 6) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13a | · | 13b | ^ | 14 | ^ | 15a | · | 15b | ^ | 16 | ^ | 17a | · | 17b | · | 17c | |
| SP1: | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | - |   | |   | |   | - |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for SARS2
|
Expression for SARS2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SARS2 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: --
 About this image See SARS2 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for SARS2
SOURCE GeneReport for Unigene cluster: Hs.709416 SABiosciences Custom PCR Arrays for SARS2
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SARS2 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SARS2 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SARS2 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SARS2 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SARS2 |
Orthologs for SARS2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for SARS2 gene from 9/38 species (see all 38) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
LOC1008582141 |
seryl-tRNA synthetase, mitochondrial-like |
69.45(n) 63.11(a) |
  |
100858214 XM_003643499.1 XP_003643547.1 |
tropical clawed frog (Xenopus tropicalis) |
Amphibia |
BQ390056.12 |
-- |
74.23(n) |
  |
BQ390056.1 |
zebrafish (Danio rerio) |
Actinopterygii |
BC055610.12 |
-- |
76.1(n) |
  |
394154 BC055610.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
Aats-ser1 |
Seryl-tRNA synthetase |
49.79(n) 38.42(a) |
  |
41862 NM_079641.2 NP_524365.1 |
worm (Caenorhabditis elegans) |
Secernentea |
sars-21 |
Protein SARS-2 |
50.37(n) 42.86(a) |
  |
177200 NM_068148.5 NP_500549.1 |
baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes |
DIA4(YHR011W)4 DIA41 |
Probable mitochondrial seryl-tRNA synthetase, mutant more4 Dia4p1 |
43.94(n)1 33.97(a)1 |
  |
8(127780-129120)4 8564021, 4 NP_011875.11, 4 |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
SRS1 |
Seryl-tRNA synthetase |
47.45(n) 40.85(a) |
  |
837734 NM_101058.2 NP_172651.1 |
rice (Oryza sativa) |
Liliopsida |
Os11g06109001 |
hypothetical protein |
49.87(n) 43.83(a) |
  |
4350906 NM_001074797.1 NP_001068265.1 |
E. coli (Escherichia coli) |
Gamma proteobacteria |
serS6 |
seryl-tRNA synthetase, also charges selenocysteiny... |
25(a) |
possible ortholog |
Chromosome(938651-939943) |
ENSEMBL Gene Tree for SARS2 (if available) TreeFam Gene Tree for SARS2 (if available)  |
Paralogs for SARS2 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for SARS2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 19 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for SARS2 (39405904 - 39466380 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for SARS2: -- Human Gene Mutation Database (HGMD): SARS2
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SARS2 |
|
Disorders
/ Diseases for SARS2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SARS2 for disorders About GeneDecksing
OMIM gene information: 612804
OMIM disorders: --
UniProtKB/Swiss-Prot: SYSM_HUMAN, Q9NP81
Defects in SARS2 are the cause of hyperuricemia pulmonary hypertension renal failure and alkalosis (HUPRA)[MIM:613845]. HUPRA is a multisystem disorder characterized by onset in infancy of progressive renal failure leadingto electrolyte imbalances, metabolic alkalosis, pulmonary hypertension, hypotonia, and delayed development. Affectedindividuals are born prematurely 10 diseases for SARS2: About MalaCardshyperuricemia, pulmonary hypertension, renal failure, and alkalosis hyperuricemia pulmonary hypertension hypotonia hypertension myopathy pneumonia tuberculosis malaria mycobacterium tuberculosis Human Genome Epidemiology (HuGE) Navigator: SARS2 (1 document) Export disorders for SARS2 gene to outside databases
|
Publications for SARS2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SARS2 gene, integrated from 9 sources (see all 24): (articles sorted by number of sources associating them with SARS2) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Characterization and tRNA recognition of mammalian mitochondrial seryl-tRNA synthetase. (PubMed id 10764807)1, 2, 3, 9 Yokogawa T.... Watanabe K. (2000)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Novel coding-region polymorphisms in mitochondrial seryl-tRNA synthetase (SARSM) and mitoribosomal protein S12 (RPMS12) genes in DFNA4 autosomal dominant deafness families. (PubMed id 11317363)1, 9 Shah Z.H....Jacobs H.T. (2001)
- NF-Y influences directionality of transcription from the bidirectional Mrps12/Sarsm promoter in both mouse and human cells. (PubMed id 19439209)1, 9 Zanotto E....Jacobs H.T. (2009)
- Modulation of Mrps12/Sarsm promoter activity in response to mitochondrial stress. (PubMed id 18755224)1, 9 Zanotto E....Jacobs H.T. (2008)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- A cohesin-RAD21 interactome. (PubMed id 22145905)1 Panigrahi A.K....Pati D. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
|
External Searches for SARS2 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing SARS2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SARS2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SARS2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for SARS2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SARS2 gene: Search GeneIP for patents involving SARS2
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products for SARS2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
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| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for SARS2 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SARS2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SARS2 | | OriGene Protein Over-expression Lysate for SARS2 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for SARS2 | | OriGene 3'-UTR Clone for SARS2 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SARS2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SARS2 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for SARS2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for SARS2 | | OriGene Custom Protein Services for SARS2 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SARS2 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SARS2 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SARS2 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SARS2 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SARS2 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SARS2 |
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| | | Search Tocris compounds for SARS2 |
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 | | SARS2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SARS2 |
|  |  |  |  | | | ThermoFisher Antibodies for SARS2 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SARS2 |
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