SARM1 Gene
protein-coding GIFtS: 51
GCID: GC17P026698
|
|
sterile alpha and TIR motif containing 1
| |
Aliases
for SARM1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Sterile Alpha And TIR Motif Containing 11 2 | | Tir-1 Homolog2 3 | | SARM1 2 3 5 | | MyD88-52 3 | | SAMD21 2 3 | | SAM Domain-Containing Protein 22 3 | | KIAA05241 3 5 | | Sterile Alpha And HEAT/Armadillo Motif Protein, Ortholog Of Drosophila2 | | Sterile Alpha And Armadillo Repeat Protein2 3 | | Sterile Alpha And TIR Motif-Containing Protein 12 | | Sterile Alpha Motif Domain-Containing Protein 22 3 | | |
Export aliases for SARM1 gene to outside databasesPrevious GC identifers: GC17P026550 GC17P026844 GC17P023723 GC17P026685 GC17P022907 |
Summaries
for SARM1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: SARM1_HUMAN, Q6SZW1Function: Negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway which plays a pivotalrole in activating axonal degeneration following injury. Promotes Wallerian degeneration an injury-induced axonaldeath pathway which involves degeneration of an axon distal to the injury site. Can activate neuronal death inresponse to stress. Regulates dendritic arborization through the MAPK4-JNK pathway. Involved in innate immuneresponse. Inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1, TRIF-dependent activation ofNF-kappa-B and IRF3, and the phosphorylation of MAPK14/p38
|
Genomic Views
for SARM1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010799.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SARM1 gene promoter:
AhR p300 NRSF form 1 NF-kappaB NRSF form 2 GATA-2 ARP-1 NF-kappaB1 LyF-1 ATF
Other transcription factors
Search SABiosciences Chromatin IP Primers for SARM1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SARM1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q11 Ensembl cytogenetic band: 17q11.2 HGNC cytogenetic band: 17q11SARM1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P026698: view genomic region
(about GC identifiers)
Start:
|
26,691,378 bp from pter |
End:
|
26,728,065 bp from pter |
Size:
|
36,688 bases |
Orientation:
|
plus strand |
|
Proteins
for SARM1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SARM1_HUMAN, Q6SZW1 (See
protein sequence)Recommended Name: Sterile alpha and TIR motif-containing protein 1 precursor Size: 724 amino acids; 79388 Da
Subunit: Interacts with TICAM1/TRIF and thereby interferes with TICAM1/TRIF function. Interacts with MAPK10/JNK3 andSDC2 (via cytoplasmic domain) (By similarity)
Subcellular location: Cytoplasm. Cell projection, axon (By similarity). Cell projection, dendrite (By similarity). Celljunction, synapse (By similarity). Mitochondrion. Note=Associated with microtubules (By similarity)
Caution: Was initially (PubMed:11386760) reported to contain ARM repeats. Such repeats are however not predicted by anydetection method
Secondary accessions: O60277 Q7LGG3 Q9NXY5Alternative splicing: 2 isoforms: Q6SZW1-1 Q6SZW1-2 Explore the universe of human proteins at neXtProt for SARM1: NX_Q6SZW1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6SZW1
SARM1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055892.2
ENSEMBL proteins: ENSP00000406738 ENSP00000464166 ENSP00000462479 ENSP00000462228 Reactome Protein details: Q6SZW1
Human Recombinant Protein Products:
Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8): About this table
SARM1 for ontologies About GeneDecksing
SARM1 Antibody Products:
Assay Products for SARM1: |
Protein
Domains /
Families
for SARM1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SARM1 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q6SZW1ProtoNet protein and cluster: Q6SZW1 2 Blocks protein families: IPB001660 Sterile alpha motif SAM IPB011510 Sterile alpha motif homology 2
UniProtKB/Swiss-Prot: SARM1_HUMAN, Q6SZW1Similarity: Contains 2 SAM (sterile alpha motif) domainsSimilarity: Contains 1 TIR domain |
Function
for SARM1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SARM1_HUMAN, Q6SZW1Function: Negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway which plays a pivotalrole in activating axonal degeneration following injury. Promotes Wallerian degeneration an injury-induced axonaldeath pathway which involves degeneration of an axon distal to the injury site. Can activate neuronal death inresponse to stress. Regulates dendritic arborization through the MAPK4-JNK pathway. Involved in innate immuneresponse. Inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1, TRIF-dependent activation ofNF-kappa-B and IRF3, and the phosphorylation of MAPK14/p38Induction: Up-regulated by lipopolysaccharides (LPS)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SARM1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SARM1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SARM1 (NM_015077) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SARM1 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SARM1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SARM1 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
-- | -- |
SARM1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for SARM1:
Animal Models:
Mouse knock-out Sarm1tm1Aidi for SARM1
2 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Sarm1):
SARM1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for SARM1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | TRAF6 Mediated Induction of proinflammatory cytokines | | | 2 | Immune System | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/7 
Reactome Pathways for SARM1 (see all 7)
SARM1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SARM1
5/21 Interacting proteins for SARM1 (Q6SZW13) via UniProtKB, MINT, STRING, and/or I2D (see all 21)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007165 | signal transduction |
IEA | -- | | GO:0009749 | response to glucose stimulus |
-- | -- | | GO:0042981 | regulation of apoptotic process |
-- | -- | | GO:0045087 | innate immune response |
IEA | -- | | GO:0048814 | regulation of dendrite morphogenesis |
ISS | -- |
SARM1 for ontologies About GeneDecksing
|
Drugs & Compounds
for SARM1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SARM1
Search CenterWatch for drugs/clinical trials and news about SARM1
|
Transcripts
for SARM1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SARM1 gene: NM_015077.2 Unigene Cluster for SARM1: Sterile alpha and TIR motif containing 1 Hs.743510 [show with all ESTs]Unigene Representative Sequence: NM_0150778 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000379061(uc010waj.1) ENST00000457710(uc010crl.1 uc002hbe.1)
ENST00000003834 ENST00000582323 ENST00000578128 ENST00000577870 ENST00000580711
ENST00000579593
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SARM1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SARM1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SARM1 (NM_015077) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SARM1 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SARM1 |
Additional cDNA sequence: AB011096.1 AF086363.1 AJ290445.1 AK026397.1 AK093615.1 AK302038.1 AK314609.1 AY444166.1 BC040429.1 BC122860.1 8 DOTS entries: DT.95373041 DT.99968346 DT.100782897 DT.40240655 DT.100025807 DT.120988319 DT.99941606 DT.120988299 24/102 AceView cDNA sequences (see all 102): AA729916 CR623769 BM791687 BU178839 CR626592 BX106603 AA281090 BM795235 BX090713 AW770507 CR616327 BQ068917 AA281198 NM_015077 BQ894414 BX483880 BC040429 AI962488 AY444166 BQ899207 AI360056 AL565643 BU151384 AJ290445
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for SARM1 (see all 8) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | · | 9c | ^ | 10a | · | 10b | · | 10c | · | 10d | ^ | 11a | · | 11b | · | 11c | ^ | 12a | · | 12b | · | 12c |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | | | - | | | | | | | | | | | | - | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | | | | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | - | | | | - | | - | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | - | | | | | | | | | | | | - | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | - | | | | | | | |
ECgene alternative splicing isoforms for SARM1
|
Expression
for SARM1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SARM1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GATATGACAA
About this image
See SARM1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SARM1
SOURCE GeneReport for Unigene cluster: Hs.743510
UniProtKB/Swiss-Prot: SARM1_HUMAN, Q6SZW1Tissue specificity: Predominantly expressed in brain, kidney and liver. Expressed at lower level in placenta
SABiosciences Expression via Pathway-Focused PCR Array including SARM1: | Toll-Like Receptor Signaling Pathway in human mouse rat |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SARM1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SARM1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SARM1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SARM1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SARM1 |
Orthologs
for SARM1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SARM1 gene from 6/16 species (see all 16) About this table
ENSEMBL Gene Tree for SARM1 (if available)
TreeFam Gene Tree for SARM1 (if available) |
Paralogs
for SARM1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for SARM1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SARM1 (26691378 - 26728065 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SARM1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SARM1 |
|
Disorders
/ Diseases
for SARM1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SARM1 for disorders About GeneDecksing
OMIM gene information: 607732
OMIM disorders: --
8  diseases for SARM1: About MalaCardsretinoschisis chronic lymphocytic leukemia lymphocytic leukemia hypogonadism
osteoporosis leukemia retinitis neuronitis
1 disease from the University of Copenhagen DISEASES database for SARM1:Retinoschisis Human Genome Epidemiology (HuGE) Navigator: SARM1 (4 documents)
Export disorders for SARM1 gene to outside databases
|
Publications
for SARM1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SARM1 gene, integrated from 9 sources (see all 23):
(articles sorted by number of sources associating them with SARM1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9628581)1, 2, 3 Nagase T....Ohara O. (1998)
- Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response. (PubMed id 15123841)1, 2, 9 Liberati N.T....Ausubel F.M. (2004)
- Targeting of pro-apoptotic TLR adaptor SARM to mitocho ndria: definition of the critical region and residues in the signal sequence. (PubMed id 22145856)1, 2 Panneerselvam P....Ding J.L. (2012)
- SARM inhibits both TRIF- and MyD88-mediated AP-1 acti vation. (PubMed id 20306472)1, 2 Peng J....Ding J.L. (2010)
- Studies of SARM1 uncover similarities between immune and neuronal responses to danger. (PubMed id 18089857)1, 2 Dalod M. (2007)
- The human adaptor SARM negatively regulates adaptor protein TRIF- dependent Toll-like receptor signaling. (PubMed id 16964262)1, 2 Carty M....Bowie A.G. (2006)
- A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/beta-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans. (PubMed id 11386760)1, 2 Mink M.... Csiszar K. (2001)
- The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
- Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. (PubMed id 21903422)1 Li S....Dorf M.E. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
|
External Searches for SARM1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SARM1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SARM1 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing SARM1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SARM1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SARM1 gene:
Search GeneIP for patents involving SARM1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SARM1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for SARM1 | | OriGene shRNA RFP for SARM1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SARM1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SARM1 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SARM1 | | OriGene 3'-UTR Clone for SARM1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SARM1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SARM1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SARM1 | | OriGene Custom Protein Services for SARM1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SARM1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SARM1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SARM1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SARM1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SARM1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SARM1 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for SARM1 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SARM1 |
|  |  |  | | | | ThermoFisher Antibodies for SARM1 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SARM1 |
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