SARDH Gene
protein-coding GIFtS: 56
GCID: GC09M136528
|
|
sarcosine dehydrogenase
(Previous symbol: DMGDHL1)
| |
Aliases
for SARDH gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Sarcosine Dehydrogenase1 2 | | SARD2 5 | | DMGDHL11 2 3 | | Dimethylglycine Dehydrogenase-Like 12 | | SDH1 2 | | Sarcosine Dehydrogenase, Mitochondrial2 | | BPR-22 3 | | EC 1.5.8.33 | | SAR2 5 | | SarDH3 |
Export aliases for SARDH gene to outside databasesPrevious GC identifers: GC09M127604 GC09P128054 GC09M129954 GC09M131870 GC09M133558 GC09M135518 GC09M106029 |
Summaries
for SARDH gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SARDH:
This gene encodes an enzyme localized to the mitochondrial matrix which catalyzes the oxidative demethylation ofsarcosine. This enzyme is distinct from another mitochondrial matrix enzyme, dimethylglycine dehydrogenase, whichcatalyzes a reaction resulting in the formation of sarcosine. Mutations in this gene are associated with sarcosinemia.Alternatively spliced transcript variants have been described. (provided by RefSeq, Oct 2008)
Gene Wiki entry for SARDH
|
Genomic Views
for SARDH gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_035014.4
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SARDH gene promoter:
N-Myc Zic1 NF-kappaB Tal-1beta ITF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for SARDH
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SARDH |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9q33-q34 Ensembl cytogenetic band: 9q34.2 HGNC cytogenetic band: 9q33-q34SARDH Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09M136528: view genomic region
(about GC identifiers)
Start:
|
136,528,682 bp from pter |
End:
|
136,605,077 bp from pter |
Size:
|
76,396 bases |
Orientation:
|
minus strand |
|
Proteins
for SARDH gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SARDH_HUMAN, Q9UL12 (See
protein sequence)Recommended Name: Sarcosine dehydrogenase, mitochondrial precursor Size: 918 amino acids; 101037 Da
Cofactor: Binds 1 FAD covalently per monomer (By similarity)
Subcellular location: Mitochondrion matrix (By similarity)
Sequence caution: Sequence=AAD33412.1; Type=Frameshift; Positions=867;
Secondary accessions: B2RMR5 B7ZLT6 Q5SYV0 Q9Y280 Q9Y2Y3Explore the universe of human proteins at neXtProt for SARDH: NX_Q9UL12
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UL12
SARDH Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001128179.1 NP_009032.2
ENSEMBL proteins: ENSP00000360938 ENSP00000360934 ENSP00000394210 ENSP00000360933 ENSP00000403084 ENSP00000415537 ENSP00000298628
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
SARDH for ontologies About GeneDecksing
SARDH Antibody Products:
Assay Products for SARDH: |
Protein
Domains /
Families
for SARDH gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SARDH for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9UL12ProtoNet protein and cluster: Q9UL12 1 Blocks protein family: IPB006222 Glycine cleavage T protein (aminomethyl transferase)
UniProtKB/Swiss-Prot: SARDH_HUMAN, Q9UL12Similarity: Belongs to the GcvT family |
Function
for SARDH gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SARDH_HUMAN, Q9UL12Catalytic activity: Sarcosine + H(2)O + electron-transfer flavoprotein = glycine + formaldehyde + reducedelectron-transfer flavoprotein Genatlas biochemistry entry for SARDH:sarcosine dehydrogenase,catalyzing qlycine synthesis,"one-carbone" metabolism,liver motochondrial flavoenzyme
Enzyme Number (IUBMB): EC 1.5.8.31
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SARDH (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SARDH (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): SARDH (NM_007101) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SARDH | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SARDH |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SARDH |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004047 | aminomethyltransferase activity |
IEA | -- | | GO:0008480 | sarcosine dehydrogenase activity |
IEA | -- | | GO:0016491 | oxidoreductase activity |
-- | -- | | GO:0050660 | flavin adenine dinucleotide binding |
-- | -- |
SARDH for ontologies About GeneDecksing
|
Pathways & Interactions
for SARDH gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | glycine betaine degradation | | | 2 | Glycine, serine and threonine metabolism | | | 3 | Metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for SARDH
2 
Kegg Pathways (Kegg details for SARDH):
UniProtKB/Swiss-Prot: SARDH_HUMAN, Q9UL12Pathway: Amine and polyamine degradation; sarcosine degradation; formaldehyde and glycine from sarcosine: step 1/1
SARDH for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SARDH
STRING Interaction
Network Preview (showing 5 interactants - click image to see 14)
5/14 Interacting proteins for SARDH (ENSP000003609384) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006546 | glycine catabolic process |
IEA | -- | | GO:0008150 | biological_process |
-- | -- |
SARDH for ontologies About GeneDecksing
|
Drugs & Compounds
for SARDH gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SARDH for compounds About GeneDecksing
 Browse Tocris compounds for SARDH
10/11 HMDB Compounds for SARDH (see all 11) About this table
9 Novoseek chemical compound relationships for SARDH gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| sarcosine |
93.9 |
35 |
10444331 (4), 9528896 (2), 1700744 (1), 1372986 (1) (see all 17) |
| dimethylglycine |
90 |
5 |
10444331 (1), 9528896 (1), 11122247 (1), 14744856 (1) (see all 5) |
| mannitol |
55.2 |
7 |
15658461 (1), 8753449 (1), 10503458 (1), 11954740 (1) (see all 7) |
| n-ethyl-n-nitrosourea |
52.7 |
1 |
8812433 (1) |
| flavin |
51.6 |
1 |
15069080 (1) |
| succinate |
27.5 |
2 |
9528896 (1), 10448053 (1) |
| folate |
14.6 |
2 |
10767172 (1) |
| creatinine |
13.7 |
2 |
10448053 (1), 20347908 (1) |
| lactate |
0 |
1 |
8621045 (1) |
Search CenterWatch for drugs/clinical trials and news about SARDH
|
Transcripts
for SARDH gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SARDH gene (2 alternative transcripts): NM_001134707.1 NM_007101.3 Unigene Cluster for SARDH: Sarcosine dehydrogenase Hs.198003 [show with all ESTs]Unigene Representative Sequence: NM_0071018 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000371872(uc004ceo.3 uc011mdo.2 uc011mdn.2) ENST00000371868(uc004cen.3)
ENST00000469828 ENST00000427237 ENST00000371867 ENST00000439388(uc004cep.4)
ENST00000422262 ENST00000298628
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SARDH (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SARDH (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): SARDH (NM_007101) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SARDH | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SARDH |
Additional cDNA sequence: AB073898.1 AF047004.1 AF047190.1 AF095735.2 AF095736.2 AF095737.2 AF129265.1 AF129266.1 AF162428.1 AJ223317.1 AK093794.1 AK223402.1 AK291211.1 AK298348.1 AK316494.1 BC033217.1 BC041574.1 BC136363.1 BC136364.1 BC144035.1 12 DOTS entries: DT.40198284 DT.95157356 DT.100777178 DT.95157357 DT.100668990 DT.91787189 DT.100777179 DT.95157355 DT.101969589 DT.121145033 DT.121145085 DT.121145087 24/65 AceView cDNA sequences (see all 65): CR593278 AF095736 BE207913 AF095735 AL602561 BE294520 NM_007101 BU500834 CR597974 CB136701 CR602119 AF162428 AI566543 BX463066 AJ223317 CD675365 AI245607 AX748310 AW731973 AF095737 BE019111 BX343603 AK124777 BE293990
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for SARDH About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SARDH
|
Expression
for SARDH gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SARDH expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCTTGTAGCC
About this image
See SARDH Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SARDH
SOURCE GeneReport for Unigene cluster: Hs.198003
SABiosciences Expression via Pathway-Focused PCR Array including SARDH:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SARDH
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SARDH | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SARDH | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SARDH | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SARDH |
Orthologs
for SARDH gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SARDH gene from 5/20 species (see all 20) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
SARDH1 |
sarcosine dehydrogenase |
77.36(n)
81.71(a) |
|
417146 XM_415428.3 XP_415428.3 |
lizard
(Anolis carolinensis) |
Reptilia |
SARDH6-- |
-- |
81(a)74(a) |
1 ↔ many1 ↔ many |
GL344411.1(32212-38621) GL343736.1(225868-271553) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.126822 |
Xenopus laevis transcribed sequence with weak similarity more |
73.67(n) |
|
BJ072373.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
zgc563632 |
similar to sarcosine dehydrogenase |
76.73(n) |
|
394103 BC051605.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG63851 , 3 |
sarcosine dehydrogenase3
CG63851 |
50(a)
(best of 2)3
56.73(n)1
52.28(a)1 |
|
54E83
370261 NM_137419.21 NP_611263.11 |
ENSEMBL Gene Tree for SARDH (if available)
TreeFam Gene Tree for SARDH (if available) |
Paralogs
for SARDH gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SARDH gene
- PDPR2 DMGDH2
4 SIMAP similar genes for SARDH using alignment to 8 protein entries: SARDH_HUMAN (see all proteins):C3orf64 DSERG1 PDPR DMGDH
SARDH for paralogs About GeneDecksing
|
Genomic Variants
for SARDH gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SARDH (136528682 - 136605077 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 9 variations for SARDH
6 CNVs: 30336 30335 31532 4657 4658 0132
3 Indels: 34399 41812 70810 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SARDH |
|
Disorders
/ Diseases
for SARDH gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SARDH for disorders About GeneDecksing
OMIM gene information: 604455
OMIM disorders: 268900
UniProtKB/Swiss-Prot: SARDH_HUMAN, Q9UL12
Defects in SARDH are a cause of sarcosinemia (SAR) [MIM:268900]. Sarcosinemia is a metabolic disordercharacterized by an increased concentration of sarcosine in plasma and urine due to sarcosine dehydrogenasedeficiency. Prevalence has been estimated at 1:28'000 to 1:350'000 in newborn screening programs. Sarcosinemia is mostprobably a benign condition without significant clinical problems. It is transmitted in an autosomal recessive manner
14  diseases for SARDH: About MalaCardssarcosinemia dimethylglycine dehydrogenase deficiency spina bifida primary biliary cirrhosis
dilated cardiomyopathy metabolic disorders cardiomyopathy prostate cancer, progression of
prostate cancer hepatocellular carcinoma laryngitis pharyngitis
prostatitis carcinoma
3 Novoseek disease relationships for SARDH gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| sarcosinemia |
96.4 |
5 |
10444331 (3), 8812433 (1), 10876657 (1) |
| myocarditis |
42.9 |
1 |
9528896 (1) |
| dilated cardiomyopathy |
24.9 |
1 |
9528896 (1) |
Genatlas disease: SARDH sarcosinemia
Human Genome Epidemiology (HuGE) Navigator: SARDH (2 documents)
Export disorders for SARDH gene to outside databases
|
Publications
for SARDH gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SARDH gene, integrated from 9 sources (see all 55):
(articles sorted by number of sources associating them with SARDH) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning and mapping of the cDNA for human sarcosine dehydrogenase, a flavoenzyme defective in patients with sarcosinemia. (PubMed id 10444331)1, 2, 3, 9 Eschenbrenner M. and Jorns M.S. (1999)
- Physical and cDNA mapping in the DBH region of human chromosome 9q34. (PubMed id 10686491)1, 2 Gilbert J.R.... Pericak-Vance M.A. (2000)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Mutations in the sarcosine dehydrogenase gene in patie nts with sarcosinemia. (PubMed id 22825317)1 Bar-joseph I....Anikster Y. (2012)
- Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (2010)
- An association study of 45 folate-related genes in spina bifida: Involvement of cubilin (CUBN) and tRNA aspartic acid methyltransferase 1 (TRDMT1). (PubMed id 19161160)1 Franke B....Blom H.J. (2009)
- Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in canonical Wnt signal transduction. (PubMed id 17693683)2 Tang L.Y....Zeng R. (2007)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)2 Humphray S.J.... Dunham I. (2004)
|
External Searches for SARDH gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SARDH gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SARDH gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SARDH gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SARDH | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SARDH gene:
Search GeneIP for patents involving SARDH
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for SARDH gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SARDH | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SARDH | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SARDH | | | OriGene Protein Over-expression Lysate for SARDH | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SARDH | | OriGene 3'-UTR Clone for SARDH | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SARDH | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SARDH | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SARDH | | OriGene Custom Protein Services for SARDH | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SARDH | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SARDH | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SARDH | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SARDH | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SARDH | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SARDH |
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| | | | Search Tocris compounds for SARDH |
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 | | | SARDH Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SARDH |
|  |  |  | | | | ThermoFisher Antibodies for SARDH |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SARDH |
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