Aliases for SARDH Gene
External Ids for SARDH Gene
Previous HGNC Symbols for SARDH Gene
Previous GeneCards Identifiers for SARDH Gene
This gene encodes an enzyme localized to the mitochondrial matrix which catalyzes the oxidative demethylation of sarcosine. This enzyme is distinct from another mitochondrial matrix enzyme, dimethylglycine dehydrogenase, which catalyzes a reaction resulting in the formation of sarcosine. Mutations in this gene are associated with sarcosinemia. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2008]
GeneCards Summary for SARDH Gene
SARDH (Sarcosine Dehydrogenase) is a Protein Coding gene. Diseases associated with SARDH include sarcosinemia and dimethylglycine dehydrogenase deficiency. Among its related pathways are Metabolism and Glycine, serine and threonine metabolism. GO annotations related to this gene include aminomethyltransferase activity and sarcosine dehydrogenase activity. An important paralog of this gene is PDPR.