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SAPS2 Gene

protein-coding GIFtS: 57

GC22P049072

SAPS domain family, member 2
(Previous name: KIAA0685 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: KIAA0685)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
KIAA0685 ^¹, ², ³, ⁵
PP6R2 ^², ³, ⁵
SAP190 ^¹, ²
dJ579N16.1 ^¹, ²

Descriptions
SAPS domain family member 2 ^³
SAPS domain family, member 2 ^²

External Ids
HGNC: 19253¹
Entrez Gene: 9701²
UniProtKB: O75170³
Ensembl: ENSG00000100239⁷

Search outside databases for aliases for SAPS2 gene

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for SAPS2:

Protein phosphatase regulatory subunits, such as SAPS2, modulate the activity of protein

phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and

determining the intracellular localization of the holoenzyme. SAPS2 is a regulatory subunit for

the protein phosphatase-6 catalytic subunit (PPP6C; MIM 300141) (Stefansson and Brautigan, 2006

[PubMed 16769727]).[supplied by OMIM]

UniProtKB/Swiss-Prot: SAPS2_HUMAN, O75170

Function: Regulatory subunit of protein phospatase 6 (PP6). May function as a scaffolding PP6

subunit. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in

response to TNF-alpha

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the SAPS2 gene

Entrez Gene cytogenetic band: 22q13.33 Ensembl cytogenetic band: 22q13.33 HGNC cytogenetic band: 22q13.33

SAPS2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 22 GeneLoc Exon Structure

GeneLoc location for GC22P049072: (about GC identifiers)

Start:	49,128,599 bp from pter
End:	49,230,380 bp from pter
Size:	101,782 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000022.9 NT_011526.6

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: SAPS2_HUMAN, O75170 (See protein sequence)

Recommended Name: Serine/threonine-protein phosphatase 6 regulatory subunit 2

Size: 966 amino acids; 104942 Da

Subunit: Protein phospatase 6 (PP6) holoenzyme is proposed to be a heterotrimeric complex formed by

the catalytic subunit, a SAPS domain-containing subunit (PP6R) and an ankyrin repeat-domain

containing regulatory subunit (ARS). Interacts with PPP6C and NFKBIE. Interacts with ANKRD28

Subcellular location: Cytoplasm

Secondary accessions: A6PVG3 Q7Z5G5 Q9UGB9

Alternative splicing: 2 isoforms: O75170-1 O75170-2

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_055493.2

ENSEMBL proteins:

ENSP00000379095 ENSP00000352051 ENSP00000379090 ENSP00000379093 ENSP00000216061 ENSP00000384532

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (SAPS2)
	Human Recombinant Proteins from Abnova (SAPS2)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--

About this table

Antibodies for SAPS2:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse Antibodies at Sigma-Aldrich
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (SAPS2), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (SAPS2)
	Novus Biologicals Antibodies for SAPS2

Assays for SAPS2:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry O75170

ProtoNet protein and cluster: O75170

1 Blocks protein family: IPB007587 SIT4 phosphatase-associated protein

UniProtKB/Swiss-Prot: SAPS2_HUMAN, O75170

Similarity: Belongs to the SAPS family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (SAPS2)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): BC006568

Applied Biosystems Silencer® siRNAs for SAPS2

Sigma-Aldrich siRNA for SAPS2

Sigma-Aldrich shRNA for SAPS2

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for SAPS2
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_014678
Myc/DDK tagged cDNA clone in CMV expression vector: NM_014678
untagged cDNA clones in CMV expression vector (see all 4): BC006568

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_014678

UniProtKB/Swiss-Prot: SAPS2_HUMAN, O75170

Function: Regulatory subunit of protein phospatase 6 (PP6). May function as a scaffolding PP6

subunit. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in

response to TNF-alpha

1 Gene Ontology (GO) molecular function term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	16769727 18186651

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

3 Interacting proteins for SAPS2 (ENSP00000216061³ O75170^{1, 2}) via UniProtKB, MINT, and/or STRING

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
PPP6C	O00743¹	STRING (score=.972) EBI-359739, EBI-359751
NFKBIE	O00221¹^,²	STRING (score=.973) EBI-359739, EBI-355098 MINT-47945 EBI-359739, EBI-355098 MINT-47945
ANKRD28	O15084¹	EBI-359739, EBI-359567
NFKBIE	O00221¹^,²	STRING (score=.973) EBI-359739, EBI-355098 MINT-47945 EBI-359739, EBI-355098 MINT-47945
NFKBIE	O00221¹^,²	STRING (score=.973) EBI-359739, EBI-355098 MINT-47945 EBI-359739, EBI-355098 MINT-47945

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for SAPS2

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (SAPS2)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): BC006568

Sigma-Aldrich siRNA for SAPS2

Sigma-Aldrich shRNA for SAPS2

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_014678

REFSEQ mRNAs for SAPS2 gene:

NM_014678.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_014678

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_014678
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_014678
                                 untagged cDNA clones in CMV expression vector (see all 4): BC006568

Additional cDNA sequence:

AB014585.1 AK002063.1 AK022669.1 AK302472.1 BC000976.4 BC006568.2 BC032664.1 BC041698.1

BC052995.2 CR611290.1

24/39 DOTS entries (see all 39 ):

DT.448541 DT.100796870 DT.91754729 DT.100796851 DT.101984931 DT.100811416 DT.40296258 DT.95129220

DT.100796869 DT.95129217 DT.100796866 DT.95129242 DT.100796868 DT.120634500 DT.100699279 DT.95362164

DT.100796867 DT.91721997 DT.91746235 DT.100796860 DT.100811415 DT.102838633 DT.120634528 DT.120634577

24/324 AceView cDNA sequences (see all 324 ):

H55503 BM708928 CD742832 BC000976 F29393 BM806913 BQ643762 AA897448

BM789768 CA432857 AI459136 AW204394 BX508819 BQ648390 BQ937868 CK903718

AI739063 BU186078 AA991740 BM772885 AL046689 AW134896 NM_014678 BX487177

highest scoring ESTs for SAPS2:

AB014585 AA120796 AA341237 AA405797 AA550804 AA577405 AA595366 AA642372 AA676532 AA765065

Unigene Cluster for SAPS2:

SAPS domain family, member 2

Hs.449098 [show with all ESTs]

Unigene Representative Sequence: NM_014678

GeneLoc Exon Structure

5/15 Alternative Splicing Database (ASD) splice patterns (SP) for SAPS2 (see all 15 )

ExUns:	1a	·	1b	·	1c	·	1d	^	2a	·	2b	·	2c	^	3	^	4a	·	4b	^	5	^	6a	·	6b	^	7a	·	7b	·	7c	^	8	^	9	^	10a	·	10b	^	11	^	12a	·	12b	^	13	^	14	^	15a	·
SP1:									-		-		-		-
SP2:									-		-		-		-
SP3:									-		-		-		-
SP4:
SP5:

ExUns:	15b	^	16	^	17	^	18	^	19	^	20	^	21	^	22a	·	22b	^	23	^	24	^	25a	·	25b	^	26
SP1:					-												-						-
SP2:					-												-						-
SP3:					-												-						-
SP4:																	-						-
SP5:					-												-						-

About this scheme

ECgene alternative splicing isoforms for SAPS2

6 Ensembl transcripts including schematic representations:

ENST00000395746 ENST00000359139 ENST00000395741 ENST00000395744 ENST00000216061 ENST00000401672

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

SAPS2 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for SAPS2

¹ / ² / ³

7 probe-sets matching SAPS2 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
40224_s_at²^{, 3}	U95-A	2	1.00	0.94	0.95	1.05	AB014585	1.00	0.87	0.94	1
77912_at²^{, 3}	U95-D	1	0.44	1.00	0.73	0.96	AI459136	0.60	1.00	0.82	1
202792_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_014678	0.60	1.00	0.82	1
202791_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AK022669	0.80	1.00	0.91	1
202792_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
202791_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
1570210_x_at*²	U133Plus2	NULL	0.00	0.00	--	--	--	--	--	--	--

GeneDecks SAPS2 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TCGTCCTAGA

SOURCE GeneReport for Unigene cluster: Hs.449098
Expression variation in blood from EXPOLDB for SAPS2
UniProtKB/Swiss-Prot: SAPS2_HUMAN, O75170
Tissue specificity: Ubiquitously expressed with strongest expression in the testis followed by
liver, heart, kidney, brain and placenta

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for SAPS2 gene from 5/9 species (see all 9 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	SAPS2¹	--	SAPS domain family, member 2	76.79(n) 74.04(a)	481191 XM_538312.2 XP_538312.2
chimpanzee (Pan troglodytes)	SAPS2¹	--	SAPS domain family, member 2	95.09(n) 94.73(a)	458987 XM_001141555.1 XP_001141555.1
rat (Rattus norvegicus)	Saps2¹	--	SAPS domain family, member 2	83.66(n) 82.21(a)	300146 XM_217014.4 XP_217014.4
mouse (Mus musculus)	Saps2^{1, 5}	15⁵	SAPS domain family, member 2^{1, 5}	84.24(n)¹ 82.93(a)¹	71474¹ NM_026813.1¹ NP_081089.1¹ AK004079⁵ AK018403⁵ (see all 14)
zebrafish (Danio rerio)	DKEY-266M15.7¹	--	novel protein with a SIT4 phosphatase-associated protein more	63.4(n) 56.82(a)	565779 XM_689049.3 XP_694141.3

About this table Species with no ortholog for SAPS2

ENSEMBL Gene Tree for SAPS2

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for SAPS2 gene

SAPS1² SAPS3²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/699 NCBI SNPs in SAPS2 are shown (see all 699 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 127)

AB	SNP ID	Valid	Chr 22 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs756014^1,2	A,C,F,H,O	49230827(-)	`GGCGGT/CGAGAA`	1	--	ng3¹		13	MN EU EA WA NA	1226
	rs761744^1,2	A,C,F,H	49230594(+)	`ACTTCG/ACCTAA`	1	--	ng3¹		9	NA EA MN EU WA	1018
--	rs13057311^1,2	A,C,F,H	49225062(+)	`GGTGAG/AGGACG`	1	K/R	mis¹ ese³		8	NA EU EA WA	620
	rs1076780^1,2	C,F,H	49230225(+)	`GCACTG/AGGGGC`	1	--	ut3¹ ese³		10	NA PA EA WA MN	846
	rs11555194^1,2	C,F,H	49223528(+)	`GATGAT/GGAGGA`	1	E/D	mis¹ ese³		8	EU EA WA	812
	rs9617007^1,2	F,H	49230277(+)	`TCCTAG/AAAGGG`	1	--	ut3¹ ese³		4	EU EA WA	416
--	rs1056676^1,2	F	49229924(+)	`TTTTTT/GTTGTT`	1	--	ut3¹		1	MN	184
	rs4824131^1,2	A,C,F,H	49224032(+)	`GAAGCC/GCCCCC`	1	A/A	syn¹ ese³		5	MN EA WA NA	548
--	rs2273260^1,2	C,F	49226313(+)	`GAGGCT/GGTCGG`	1	A/A	syn¹ ese³		2	EA MN	910
	rs1005536^1,2	A,C,F,H,O	49216781(+)	`GACACG/AGGGGC`	1	--	int¹		8	EA NA EU WA	572

About this table

HapMap Linkage Disequilibrium images for SAPS2 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 610877

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/11 PubMed articles for SAPS2 gene (see all 11 ):

Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811)^{2, 3, 4} Ishikawa K....Ohara O. (1998)
Protein phosphatase 6 regulatory subunits composed of ankyrin repeat domains. (PubMed id 18186651)^{3, 4} Stefansson B.... Brautigan D.L. (2008)
Protein phosphatase 6 subunit with conserved Sit4-associated protein domain targets IkappaBepsilon. (PubMed id 16769727)^{3, 4} Stefansson B. and Brautigan D.L. (2006)
The DNA sequence of human chromosome 22. (PubMed id 10591208)^{3, 4} Dunham I....O'Brien K.P. (1999)
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)⁴ Daub H.... Mann M. (2008)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)⁴ Dephoure N.... Gygi S.P. (2008)
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)³ Lim J....Zoghbi H.Y. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)⁴ Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)³ Ota T....Sugano S. (2004)
A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. (PubMed id 14743216)³ Bouwmeester T....Superti-Furga G. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 9701	HGNC: 19253	AceView: KIAA0685	Ensembl:ENSG00000100239	euGenes: HUgn9701
ECgene: SAPS2	H-InvDB: SAPS2

(According to HUGE)
About This Section

HUGE: KIAA0685

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for SAPS2
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for SAPS2:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for SAPS2-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for SAPS2		Browse antibodies at Sigma-Aldrich
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for SAPS2		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (SAPS2)
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Search Tocris compounds for SAPS2

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for SAPS2

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SAPS2 Gene

protein-coding GIFtS: 57

Aliases &
Descriptions
for SAPS2

Summaries
for SAPS2

Genomic Location
for SAPS2

Proteins
for SAPS2

Protein Domains/
Families
for SAPS2

Gene Function
for SAPS2

Pathways & Interactions
for SAPS2

Drugs & Compounds
for SAPS2

Transcripts
for SAPS2

Expression
for SAPS2

Orthologs
for SAPS2

Paralogs
for SAPS2

SNPs/Variants
for SAPS2

Disorders & Mutations
for SAPS2

Medical News
for SAPS2

Publications
for SAPS2

Search for SAPS2

Genome Databases showing SAPS2

Other Databases showing SAPS2

Specialized Databases showing SAPS2

Licensable Technologies
for SAPS2

Services
for SAPS2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

SAPS2 Gene

protein-coding GIFtS: 57

Aliases & Descriptionsfor SAPS2

Summariesfor SAPS2

Genomic Locationfor SAPS2

Proteinsfor SAPS2

Protein Domains/Familiesfor SAPS2

Gene Functionfor SAPS2

Pathways & Interactionsfor SAPS2

Drugs & Compoundsfor SAPS2

Transcriptsfor SAPS2

Expression for SAPS2

Orthologsfor SAPS2

Paralogsfor SAPS2

SNPs/Variantsfor SAPS2

Disorders & Mutationsfor SAPS2

Medical Newsfor SAPS2

Publicationsfor SAPS2

Search for SAPS2

Genome Databases showing SAPS2

Other Databases showing SAPS2

Specialized Databases showing SAPS2

Licensable Technologiesfor SAPS2

Servicesfor SAPS2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for SAPS2

Summaries
for SAPS2

Genomic Location
for SAPS2

Proteins
for SAPS2

Protein Domains/
Families
for SAPS2

Gene Function
for SAPS2

Pathways & Interactions
for SAPS2

Drugs & Compounds
for SAPS2

Transcripts
for SAPS2

Expression
for SAPS2

Orthologs
for SAPS2

Paralogs
for SAPS2

SNPs/Variants
for SAPS2

Disorders & Mutations
for SAPS2

Medical News
for SAPS2

Publications
for SAPS2

Licensable Technologies
for SAPS2

Services
for SAPS2