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Aliases for SAPCD1 Gene

Aliases for SAPCD1 Gene

  • Suppressor APC Domain Containing 1 2 3 5
  • Protein G7d 3 4
  • C6orf26 3 4
  • NG23 3 4
  • Chromosome 6 Open Reading Frame 26 2
  • G7D 4

External Ids for SAPCD1 Gene

Previous HGNC Symbols for SAPCD1 Gene

  • C6orf26

Previous GeneCards Identifiers for SAPCD1 Gene

  • GC06P031732
  • GC06P031748
  • GC06P031765

Summaries for SAPCD1 Gene

GeneCards Summary for SAPCD1 Gene

SAPCD1 (Suppressor APC Domain Containing 1) is a Protein Coding gene. Among its related pathways are Ovarian Infertility Genes.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SAPCD1 Gene

Genomics for SAPCD1 Gene

Genomic Location for SAPCD1 Gene

31,762,799 bp from pter
31,764,851 bp from pter
2,053 bases
Plus strand

Genomic View for SAPCD1 Gene

Genes around SAPCD1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SAPCD1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SAPCD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for Regulatory Elements for SAPCD1 Gene

Proteins for SAPCD1 Gene

  • Protein details for SAPCD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Suppressor APC domain-containing protein 1
    Protein Accession:
    Secondary Accessions:
    • A2ABF2
    • A2ABS9
    • Q9Y335

    Protein attributes for SAPCD1 Gene

    148 amino acids
    Molecular mass:
    16650 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAI18428.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAM24986.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAM26109.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for SAPCD1 Gene


neXtProt entry for SAPCD1 Gene

Proteomics data for SAPCD1 Gene at MOPED

Post-translational modifications for SAPCD1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SAPCD1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SAPCD1 Gene

Domains & Families for SAPCD1 Gene

Protein Domains for SAPCD1 Gene


Suggested Antigen Peptide Sequences for SAPCD1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SAPCD1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for SAPCD1 Gene

Function for SAPCD1 Gene

Phenotypes for SAPCD1 Gene

genes like me logo Genes that share phenotypes with SAPCD1: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SAPCD1 Gene

Localization for SAPCD1 Gene

Subcellular locations from

Jensen Localization Image for SAPCD1 Gene COMPARTMENTS Subcellular localization image for SAPCD1 gene
Compartment Confidence
extracellular 2
cytosol 1
mitochondrion 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for SAPCD1 Gene

Pathways & Interactions for SAPCD1 Gene

SuperPathways for SAPCD1 Gene

Superpath Contained pathways
1 Ovarian Infertility Genes
genes like me logo Genes that share pathways with SAPCD1: view

Pathways by source for SAPCD1 Gene

1 BioSystems pathway for SAPCD1 Gene

Interacting Proteins for SAPCD1 Gene

Gene Ontology (GO) - Biological Process for SAPCD1 Gene


No data available for SIGNOR curated interactions for SAPCD1 Gene

Drugs & Compounds for SAPCD1 Gene

No Compound Related Data Available

Transcripts for SAPCD1 Gene

mRNA/cDNA for SAPCD1 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SAPCD1 Gene

Suppressor APC domain containing 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SAPCD1 Gene

No ASD Table

Relevant External Links for SAPCD1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SAPCD1 Gene

mRNA expression in normal human tissues for SAPCD1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

SOURCE GeneReport for Unigene cluster for SAPCD1 Gene Hs.371225

genes like me logo Genes that share expression patterns with SAPCD1: view

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SAPCD1 Gene

Orthologs for SAPCD1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SAPCD1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SAPCD1 35
  • 84.27 (n)
  • 78.09 (a)
MGC151586 36
  • 71 (a)
(Canis familiaris)
Mammalia SAPCD1 35
  • 81.17 (n)
  • 74.01 (a)
  • 74 (a)
(Mus musculus)
Mammalia Sapcd1 35
  • 78.77 (n)
  • 71.92 (a)
Sapcd1 16
Sapcd1 36
  • 71 (a)
(Pan troglodytes)
Mammalia SAPCD1 35
  • 99.81 (n)
  • 100 (a)
  • 100 (a)
(Rattus norvegicus)
Mammalia Sapcd1 35
  • 76.87 (n)
  • 68.03 (a)
(Anolis carolinensis)
Reptilia SAPCD1 36
  • 45 (a)
Species with no ortholog for SAPCD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SAPCD1 Gene

Gene Tree for SAPCD1 (if available)
Gene Tree for SAPCD1 (if available)

Paralogs for SAPCD1 Gene

No data available for Paralogs for SAPCD1 Gene

Variants for SAPCD1 Gene

Sequence variations from dbSNP and Humsavar for SAPCD1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
VAR_056889 -
VAR_056890 -

Variation tolerance for SAPCD1 Gene

Residual Variation Intolerance Score: 83.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.26; 70.24% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SAPCD1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SAPCD1 Gene

Disorders for SAPCD1 Gene

Relevant External Links for SAPCD1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SAPCD1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SAPCD1 Gene

Publications for SAPCD1 Gene

  1. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Biochemical and computational analysis of LNX1 interacting proteins. (PMID: 22087225) Wolting C.D. … McGlade C.J. (PLoS ONE 2011) 3
  4. High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PMID: 19851445) Barcellos L.F. … Criswell L.A. (PLoS Genet. 2009) 3
  5. Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse. (PMID: 14656967) Xie T. … Hood L. (Genome Res. 2003) 3

Products for SAPCD1 Gene

Sources for SAPCD1 Gene

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