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Aliases & Descriptions for SAP30BP
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| DKFZp586L2022 2 | | HCNGP 1, 2, 3 | | HTRG 1, 2, 3 | | HTRP 1, 2, 3 |
| | | Descriptions |
|---|
| HSV-1 binding 2 | | SAP30 binding protein 2 | | Transcriptional regulator protein HCNGP 3 | | transcriptional regulator protein 2 |
|
| | Search outside databases for aliases for SAP30BP gene |
Summaries for SAP30BP(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: S30BP_HUMAN, Q9UHR5Function: Induces cell death. May act as a transcriptional corepressor of a gene related to cell survival. May be involved in the regulation of beta-2-microglobulin genes |
Genomic Location for SAP30BP
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Transcription factor binding sites upstream to the SAP30BP gene 
Entrez Gene cytogenetic band: 17q25.1 Ensembl cytogenetic band: 17q25.1 HGNC cytogenetic band: 17q25.1SAP30BP Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P071175:
(about GC identifiers)
Start:
|
71,174,994 bp from pter |
End:
|
71,215,734 bp from pter |
Size:
|
40,741 bases |
Orientation:
|
plus strand |
RefSeq DNA sequence:- NC_000017.9 NT_010641.15
| Proteins for SAP30BP
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: S30BP_HUMAN, Q9UHR5 (See
protein sequence)Recommended Name: SAP30-binding protein Size: 308 amino acids; 33870 Da
Subunit: Interacts with SAP30
Subcellular location: Nucleus
Secondary accessions: Q8N1R5 Q8TDR8 Q96D27Alternative splicing: 2 isoforms: Q9UHR5-1 Q9UHR5-2 Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_037392.1
ENSEMBL proteins: ENSP00000347592 ENSP00000293208
Human Recombinant Proteins               OriGene Purified Recombinant Human Protein: SAP30BP 
1 Gene Ontology (GO) cellular component term (links to tree view): About this table
Antibodies for SAP30BP: Assays for SAP30BP: | Protein
Domains/ Families for SAP30BP(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q9UHR5
ProtoNet protein and cluster: Q9UHR5 1 Blocks protein family: IPB012479 HCNGP-like
UniProtKB/Swiss-Prot: S30BP_HUMAN, Q9UHR5Similarity: Belongs to the HCNGP family | Gene Function for SAP30BP
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_013260
Applied Biosystems Silencer® siRNAs for SAP30BP
Sigma-Aldrich siRNA for SAP30BP  Sigma-Aldrich shRNA for SAP30BP  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_013260                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_013260                                  untagged cDNA clone in CMV expression vector: NM_013260 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_013260
UniProtKB/Swiss-Prot: S30BP_HUMAN, Q9UHR5Function: Induces cell death. May act as a transcriptional corepressor of a gene related to cell survival. May be involved in the regulation of beta-2-microglobulin genesInduction: In fibroblasts by binding of HSV11 Gene Ontology (GO) molecular function term (links to tree view): About this table | Pathways & Interactions for SAP30BP
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
2 Interacting proteins for SAP30BP (ENSP000003475923 Q9UHR51, 2) via UniProtKB, MINT, and/or STRINGAbout this table
4 Gene Ontology (GO) biological process terms (links to tree view): About this table
|
Drugs & Compounds for SAP30BP(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for SAP30BP 1 Novoseek chemical compound relationship for SAP30BP gene
| Compound |
Score |
Articles |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| zinc |
33.23 |
1 |
10995766 (1) |
About this table
|
Transcripts for SAP30BP(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_013260
Sigma-Aldrich siRNA for SAP30BP  Sigma-Aldrich shRNA for SAP30BP  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_013260 REFSEQ mRNAs for SAP30BP gene: NM_013260.6
Applied Biosystems TaqMan ® Gene Expression Assays: NM_013260               OriGene GFP tagged cDNA clone in CMV expression vector: NM_013260                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_013260                                  untagged cDNA clone in CMV expression vector: NM_013260  Additional cDNA sequence: AF087869.1 AF119664.1 AF450482.1 AK002202.1 AK023157.1 AK095265.1 AK098247.1 AK298060.1 AK310177.1 AL049465.1 AY082382.1 BC007592.1 BC011724.2 BC013409.2 BC030233.1 BC063793.1 BX647066.1 CR611306.1 CR618344.1 CR621811.1 24/26 DOTS entries (see all 26
): DT.75118005 DT.446148 DT.97851801 DT.100827118 DT.40108014 DT.100031045 DT.100827117 DT.95198338 DT.120933951 DT.100827120 DT.120933802 DT.120933955 DT.100799003 DT.95235979 DT.120933786 DT.91764122 DT.95235977 DT.100759960 DT.100827109 DT.100827116 DT.120933741 DT.40257380 DT.40283007 DT.75103840 24/394 AceView cDNA sequences (see all 394
):BG676274 BM809137 BQ575296 BM458645 AW005243 AU279772 BU733327 AK095265 AW071612 CA437237 BU731865 BU682923 AA350373 BG058482 BE295974 BU179689 BX338006 AW249882 AW024269 BM012075 BG257395 BM679609 BM807177 BQ073488
highest scoring ESTs for SAP30BP:AI074024 AI971125 AA036651 AA063582 AA074815 AA128916 AA314200 AA322293 AA350373 AA457232 Unigene Cluster for SAP30BP: SAP30 binding protein Hs.655088 [show with all ESTs]Unigene Representative Sequence: BX647066
GeneLoc Exon Structure
5/16 Alternative Splicing Database (ASD) splice patterns (SP) for SAP30BP (see all 16
)
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10a | · | 10b | ^ | 11a | · | 11b | · | 11c | · | 11d | ^ | 12a | · | 12b | ^ | 13a | · | |
| SP1: | |   | |   | |   | |   | - |   | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |   | - |   | |   | - |   | - |   | |   | |   | |   | - |   | |   | |   | |
| SP2: | |   | |   | |   | |   | - |   | |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |   | - |   | |   | - |   | - |   | |   | |   | |   | - |   | |   | |   | |
| SP3: | |   | |   | |   | |   | - |   | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |   | - |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |   | |
| SP4: | |   | |   | |   | |   | - |   | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |   | - |   | |   | - |   | - |   | |   | |   | |   | - |   | |   | |   | |
| SP5: | |   | |   | |   | |   | - |   | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |   | - |   | |   | - |   | - |   | |   | |   | |   | - |   | |   | |   |
| ExUns: | 13b | ^ | 14 | ^ | 15 | ^ | 16a | · | 16b | · | 16c | · | 16d | · | 16e | · | 16f | |
| SP1: | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   |
About this scheme
ECgene alternative splicing isoforms for SAP30BP
2 Ensembl transcripts including schematic representations: ENST00000355423
ENST00000293208
|
Expression for SAP30BP
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| SAP30BP expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for SAP30BP
1 / 2 / 3 8 probe-sets matching SAP30BP gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: GCTGGTCTGA
SOURCE GeneReport for Unigene cluster: Hs.655088
|
Orthologs for SAP30BP
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for SAP30BP gene from 5/14 species (see all 14
)
About this table Species with no ortholog for SAP30BP
ENSEMBL Gene Tree for SAP30BP | Paralogs for SAP30BP(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| -- |
SNPs/Variants for SAP30BP(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for SAP30BP (up to first 250kb)
|
Disorders & Mutations for SAP30BP
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 610218
|
Medical News for SAP30BP(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for SAP30BP (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 10/19 PubMed articles for SAP30BP gene (see all 19
):- HTRP -- an immediate-early gene product induced by HSV1 infection in human embryo fibroblasts, is involved in cellular co-repressors. (PubMed id 15496587)1, 2, 3, 4 Li J.-F.... Li Q.-H. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)3, 4 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)3, 4 Ota T....Sugano S. (2004)
- Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)3, 4 Hu R.-M.... Chen J.-L. (2000)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)4 Dephoure N.... Gygi S.P. (2008)
- A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)3 Stelzl U....Wanker E.E. (2005)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)3 Rual J.F....Vidal M. (2005)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)3 Strausberg R.L....Marra M.A. (2002)
- SAP30, a novel protein conserved between human and yeast, is a component of a histone deacetylase complex. (PubMed id 9651585)3 Zhang Y.... Reinberg D. (1998)
- Characterization of a nuclear deformed epidermal autoregulatory factor-1 (DEAF-1)-related (NUDR) transcriptional regulator protein. (PubMed id 9773984)1 Huggenvik J.I....Mowen K.A. (1998)
|
Search for SAP30BP
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing SAP30BP
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing SAP30BP
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SAP30BP(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for SAP30BP(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for SAP30BP:

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GeneCards Homepage - Last full update: 1 Jul 2009
Incremental update: 13 Oct 2009
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