Aliases for SAP130 Gene
External Ids for SAP130 Gene
Previous GeneCards Identifiers for SAP130 Gene
SAP130 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003 [PubMed 12724404]).[supplied by OMIM, Mar 2008]
GeneCards Summary for SAP130 Gene
SAP130 (Sin3A-Associated Protein, 130kDa) is a Protein Coding gene. Among its related pathways are Development NOTCH1-mediated pathway for NF-KB activity modulation and RNA Polymerase I Promoter Opening. GO annotations related to this gene include transcription coactivator activity and histone acetyltransferase activity.
UniProtKB/Swiss-Prot for SAP130 Gene
Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.