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SAMD8 Gene

protein-coding   GIFtS: 50
GCID: GC10P076859

Sterile Alpha Motif Domain Containing 8

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Sterile Alpha Motif Domain Containing 81 2     HEL-1772
Ceramide Phosphoethanolamine Synthase2 3     Epididymis Luminal Protein 1772
Sterile Alpha Motif Domain-Containing Protein 82 3     Sphingomyelin Synthase Related2
SMSr2 3     Sphingomyelin Synthase-Related Protein 12
CPE Synthase2 3     EC 2.7.8.-3
SAM Domain-Containing Protein 82 3     SMSR5

External Ids:    HGNC: 263201   Entrez Gene: 1428912   Ensembl: ENSG000001566717   OMIM: 6115755   UniProtKB: Q96LT43   

Export aliases for SAMD8 gene to outside databases

Previous GC identifers: GC10P076216 GC10P076541 GC10P070869


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SAMD8 Gene:
SAMD8 (sterile alpha motif domain containing 8) is a protein-coding gene. GO annotations related to this gene include transferase activity. An important paralog of this gene is SGMS2.

UniProtKB/Swiss-Prot: SAMD8_HUMAN, Q96LT4
Function: Sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the
primary hydroxyl of ceramide. SAMD8 is an endoplasmic reticulum (ER) transferase that has no sphingomyelin
synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine
(CPE) albeit with low product yield. Appears to operate as a ceramide sensor to control ceramide homeostasis in
the endoplasmic reticulum rather than a converter of ceramides. Seems to be critical for the integrity of the
early secretory pathway




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the SAMD8 gene promoter:
         NF-1   NF-1/L   AML1a   FOXF2   NRSF form 1   NRSF form 2   AREB6   PPAR-gamma1   HOXA5   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSAMD8 promoter sequence
   Search Chromatin IP Primers for SAMD8

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SAMD8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q22.2   Ensembl cytogenetic band:  10q22.2   HGNC cytogenetic band: 10q22.3

SAMD8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SAMD8 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P076859:  view genomic region     (about GC identifiers)

Start:
76,859,344 bp from pter      End:
76,941,881 bp from pter
Size:
82,538 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SAMD8_HUMAN, Q96LT4 (See protein sequence)
Recommended Name: Sphingomyelin synthase-related protein 1  
Size: 415 amino acids; 48321 Da
Sequence caution: Sequence=AAH80593.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: Q5JSC5 Q5JSC8 Q66K52
Alternative splicing: 2 isoforms:  Q96LT4-1   Q96LT4-2   

Explore the universe of human proteins at neXtProt for SAMD8: NX_Q96LT4

Explore proteomics data for SAMD8 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SAMD8 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001167627.1  NP_653261.1  

    ENSEMBL proteins: 
     ENSP00000391799   ENSP00000361775   ENSP00000361772   ENSP00000438042  

    SAMD8 Human Recombinant Protein Products:

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    Browse Proteins at Cloud-Clone Corp.

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SAMD: Sterile alpha motif (SAM) domain containing

    4 InterPro protein domains:
     IPR021129 SAM_type1
     IPR025749 Sphingomyelin_synth-like_dom
     IPR013761 SAM/pointed
     IPR001660 SAM

    Graphical View of Domain Structure for InterPro Entry Q96LT4

    ProtoNet protein and cluster: Q96LT4

    1 Blocks protein domain: IPB001660 Sterile alpha motif SAM

    UniProtKB/Swiss-Prot: SAMD8_HUMAN, Q96LT4
    Domain: The SAM domain is required to retain SMAD8 in the endoplasmic reticulum
    Similarity: Belongs to the sphingomyelin synthase family
    Similarity: Contains 1 SAM (sterile alpha motif) domain


    Find genes that share domains with SAMD8           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SAMD8_HUMAN, Q96LT4
    Function: Sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the
    primary hydroxyl of ceramide. SAMD8 is an endoplasmic reticulum (ER) transferase that has no sphingomyelin
    synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine
    (CPE) albeit with low product yield. Appears to operate as a ceramide sensor to control ceramide homeostasis in
    the endoplasmic reticulum rather than a converter of ceramides. Seems to be critical for the integrity of the
    early secretory pathway

         Enzyme Number (IUBMB): EC 2.7.8.-1

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0005515protein binding ----
    GO:0016740transferase activity IEA--
         
    Find genes that share ontologies with SAMD8           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for SAMD8:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SAMD8
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    Block miRNA regulation of human, mouse, rat SAMD8 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SAMD8 (see all 87):
    hsa-miR-411* hsa-miR-607 hsa-miR-106a hsa-miR-218-1* hsa-miR-200a hsa-miR-30d hsa-miR-519a hsa-miR-30a
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SAMD8_HUMAN, Q96LT4: Endoplasmic reticulum membrane; Multi-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum5
    plasma membrane3
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane NAS14685263
    GO:0030176integral component of endoplasmic reticulum membrane IDA19506037

    Find genes that share ontologies with SAMD8           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SAMD8 About    
    See pathways by source

    SuperPathContained pathways About
    1sphingomyelin metabolism/ceramide salvage
    sphingomyelin metabolism/ceramide salvage


    1 BioSystems Pathway for SAMD8
        sphingomyelin metabolism/ceramide salvage


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SAMD8
    Interactions:

        Search GeneGlobe Interaction Network for SAMD8

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    4 Interacting proteins for SAMD8 (Q96LT43 ENSP000003617724) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TGFBR1P368973, ENSP000003641334I2D: score=3 STRING: ENSP00000364133
    COPS4Q9BT783I2D: score=5 
    CLN3Q132863I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006686sphingomyelin biosynthetic process NAS14685263
    GO:0046513ceramide biosynthetic process IDA19506037
    GO:2000303regulation of ceramide biosynthetic process IDA19506037

    Find genes that share ontologies with SAMD8           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SAMD8

    Selected HMDB Compounds for SAMD8 (see all 40)    About this table
    CompoundSynonyms CAS #PubMed Ids
    LysoSM(d18:0)sphinganine-1-phosphocholine (see all 2)----
    LysoSM(d18:1)C18-Sphingosine phosphocholine (see all 7)1670-26-4--
    SM(d16:1/24:1(15Z))Sphingomyelin (d16:1/24:1(15Z)) (see all 2)----
    SM(d17:1/24:0)Sphingomyelin (d17:1/24:0) (see all 2)----
    SM(d17:1/24:1(15Z))Sphingomyelin (d17:1/24:1(15Z)) (see all 2)----
    SM(d18:0/12:0)Sphingomyelin (see all 4)----
    SM(d18:0/14:0)Sphingomyelin (see all 4)----
    SM(d18:0/14:1(9Z)(OH))C14:1-OH Sphingomyelin (see all 2)----
    SM(d18:0/16:0)Sphingomyelin (see all 4)----
    SM(d18:0/16:1(9Z)(OH))C16:1-OH Sphingomyelin (see all 2)----



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SAMD8 gene (2 alternative transcripts): 
    NM_001174156.1  NM_144660.2  

    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000447533 ENST00000372690 ENST00000372687 ENST00000542569(uc001jwx.2 uc001jwy.2)

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate SAMD8 (see all 87):
    hsa-miR-411* hsa-miR-607 hsa-miR-106a hsa-miR-218-1* hsa-miR-200a hsa-miR-30d hsa-miR-519a hsa-miR-30a
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    21 AceView cDNA sequences:

    BX280496 AK057811 BQ227867 AW991245 AI341118 NM_144660 AL600808 BI461349 
    BG778855 BP355712 BG332990 BG571120 BX510136 BE551749 BX496935 BC080593 
    BE890410 BX384859 AW991585 BX462930 BU181071 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for SAMD8    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b
    SP1:              -                                       
    SP2:                                                      


    ECgene alternative splicing isoforms for SAMD8

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SAMD8 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTCTCTTTTT
    SAMD8 Expression
    About this image

    SAMD8 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SAMD8 Protein Expression
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SAMD8 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Samd81 , 5 sterile alpha motif domain containing 81, 5 91.97(n)1
    95.66(a)1
      14 (11.86 cM)5
    676301  NM_026283.21  NP_080559.11 
     217505315 
    chicken
    (Gallus gallus)
    Aves SAMD81 sterile alpha motif domain containing 8 80.64(n)
    90.12(a)
      428946  XM_426501.4  XP_426501.3 
    lizard
    (Anolis carolinensis)
    Reptilia SAMD86
    sterile alpha motif domain containing 8
    87(a)
    1 ↔ 1
    GL343196.1(2624790-2660279)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia samd81 sterile alpha motif domain containing 8 74.53(n)
    83.29(a)
      548951  NM_001016197.2  NP_001016197.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1621831 zgc:162183 63.73(n)
    68.87(a)
      100037314  NM_001089470.1  NP_001082939.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta SMSr1 SMSr 55.15(n)
    54.38(a)
      38823  NM_139857.3  NP_648114.1 
    worm
    (Caenorhabditis elegans)
    Secernentea F53B1.21 F53B1.2 53.52(n)
    50.39(a)
      180524  NM_075988.5  NP_508389.1 


    ENSEMBL Gene Tree for SAMD8 (if available)
    TreeFam Gene Tree for SAMD8 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SAMD8 gene
    SGMS22  SGMS12  
    3 SIMAP similar genes for SAMD8 using alignment to 2 protein entries:     SAMD8_HUMAN (see all proteins):
    SGMS2    SGMS1    TMEM23

    Find genes that share paralogs with SAMD8           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SAMD8 (see all 1325)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1178276401,2
    C,F--76871088(+) TCCTGT/CCGCTT 2 -- us2k11Minor allele frequency- C:0.02EA 120
    rs1932063151,2
    --76871123(+) CCTCGC/GGCTCC 2 -- us2k10--------
    rs1843821211,2
    --76871318(+) GCGCGC/TAGTCG 2 -- us2k10--------
    rs1509942261,2
    --76871563(+) GAGCCA/GGGGGC 2 -- int10--------
    rs1150753061,2
    C,F--76871777(+) TGCGCA/GGTGGG 2 -- int11Minor allele frequency- G:0.02WA 118
    rs1409637561,2
    --76871866(+) CAGAGA/GAGCAA 2 -- int10--------
    rs1893119491,2
    --76872071(+) AAGGGC/GTGAGG 2 -- int10--------
    rs1918463511,2
    --76872079(+) AGGGAA/GGCACT 2 -- int10--------
    rs1159287731,2
    C,F--76872176(+) CATCAA/C/GAGATC 2 -- int11WA 118
    rs1448851961,2
    --76872191(+) GGGCAA/GTGTAC 2 -- int10--------

    HapMap Linkage Disequilibrium report for SAMD8 (76859344 - 76941881 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for SAMD8:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv997196CNV Deletion20482838
    esv2671037CNV Deletion23128226
    nsv7199CNV Insertion18451855
    nsv520500CNV Loss19592680
    nsv831913CNV Loss17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611575    OMIM disorders: --


    Find genes that share disorders with SAMD8           About GenesLikeMe

    Genetic Association Database (GAD): SAMD8
    Human Genome Epidemiology (HuGE) Navigator: SAMD8 (1 document)

    Export disorders for SAMD8 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SAMD8 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with SAMD8)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Sphingomyelin synthase-related protein SMSr controls ceramide homeostasis in the ER. (PubMed id 19506037)1, 2 Vacaru A.M.... Holthuis J.C. (J. Cell Biol. 2009)
    2. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Identification of a family of animal sphingomyelin synthases. (PubMed id 14685263)1, 2 Huitema K.... Holthuis J.C. (EMBO J. 2004)
    5. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    6. High-throughput mapping of a dynamic signaling network in mammalian cells. (PubMed id 15761153)1 Barrios-Rodiles M....Wrana J.L. (Science 2005)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)2 Deloukas P.... Rogers J. (Nature 2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    10. (PubMed id )2 

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
    PubMed
    OMIM
    NCBI Bookshelf
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 142891 HGNC: 26320 AceView: SAMD8 Ensembl:ENSG00000156671 euGenes: HUgn142891
    ECgene: SAMD8 H-InvDB: SAMD8

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SAMD8 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SAMD8 gene:
    Search GeneIP for patents involving SAMD8

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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