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Aliases for SAMD7 Gene

Aliases for SAMD7 Gene

  • Sterile Alpha Motif Domain Containing 7 2 3
  • SAM Domain-Containing Protein 7 4

External Ids for SAMD7 Gene

Previous GeneCards Identifiers for SAMD7 Gene

  • GC03P170950
  • GC03P171112
  • GC03P169629
  • GC03P166999

Summaries for SAMD7 Gene

GeneCards Summary for SAMD7 Gene

SAMD7 (Sterile Alpha Motif Domain Containing 7) is a Protein Coding gene. An important paralog of this gene is SAMD11.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SAMD7 Gene

Genomics for SAMD7 Gene

Regulatory Elements for SAMD7 Gene

Genomic Location for SAMD7 Gene

169,911,572 bp from pter
169,939,175 bp from pter
27,604 bases
Plus strand

Genomic View for SAMD7 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SAMD7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SAMD7 Gene

Proteins for SAMD7 Gene

  • Protein details for SAMD7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Sterile alpha motif domain-containing protein 7
    Protein Accession:
    Secondary Accessions:

    Protein attributes for SAMD7 Gene

    446 amino acids
    Molecular mass:
    49112 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SAMD7 Gene

Proteomics data for SAMD7 Gene at MOPED

Post-translational modifications for SAMD7 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SAMD7 Gene

No data available for DME Specific Peptides for SAMD7 Gene

Domains for SAMD7 Gene

Gene Families for SAMD7 Gene

Protein Domains for SAMD7 Gene

Suggested Antigen Peptide Sequences for SAMD7 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 SAM (sterile alpha motif) domain.
  • Contains 1 SAM (sterile alpha motif) domain.
genes like me logo Genes that share domains with SAMD7: view

Function for SAMD7 Gene

Gene Ontology (GO) - Molecular Function for SAMD7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with SAMD7: view
genes like me logo Genes that share phenotypes with SAMD7: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SAMD7

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SAMD7 Gene

Localization for SAMD7 Gene

Subcellular locations from

Jensen Localization Image for SAMD7 Gene COMPARTMENTS Subcellular localization image for SAMD7 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for SAMD7 Gene

Pathways for SAMD7 Gene

SuperPathways for SAMD7 Gene

No Data Available

Interacting Proteins for SAMD7 Gene

Gene Ontology (GO) - Biological Process for SAMD7 Gene


No data available for Pathways by source for SAMD7 Gene

Transcripts for SAMD7 Gene

mRNA/cDNA for SAMD7 Gene

(9) Selected AceView cDNA sequences:
(6) Additional mRNA sequences :
(3) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SAMD7 Gene

Sterile alpha motif domain containing 7:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SAMD7

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SAMD7 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9
SP1: -

Relevant External Links for SAMD7 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SAMD7 Gene

mRNA expression in normal human tissues for SAMD7 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SAMD7 Gene

This gene is overexpressed in Testis (11.7) and Spleen (5.0).

Protein differential expression in normal tissues for SAMD7 Gene

This gene is overexpressed in Heart (37.2) and Retina (31.8).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for SAMD7 Gene

SOURCE GeneReport for Unigene cluster for SAMD7 Gene Hs.439922

genes like me logo Genes that share expressions with SAMD7: view

Expression partners for SAMD7 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for SAMD7 Gene

Orthologs for SAMD7 Gene

This gene was present in the common ancestor of animals.

Orthologs for SAMD7 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SAMD7 35
  • 82.74 (n)
  • 73.09 (a)
SAMD7 36
  • 59 (a)
(Canis familiaris)
Mammalia SAMD7 35
  • 85.72 (n)
  • 79.37 (a)
SAMD7 36
  • 78 (a)
(Mus musculus)
Mammalia Samd7 35
  • 77.55 (n)
  • 66.89 (a)
Samd7 16
Samd7 36
  • 66 (a)
(Pan troglodytes)
Mammalia SAMD7 35
  • 98.95 (n)
  • 97.76 (a)
SAMD7 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Samd7 35
  • 76.03 (n)
  • 64.38 (a)
(Monodelphis domestica)
Mammalia SAMD7 36
  • 40 (a)
(Ornithorhynchus anatinus)
Mammalia SAMD7 36
  • 37 (a)
(Gallus gallus)
Aves SAMD7 36
  • 38 (a)
(Anolis carolinensis)
Reptilia SAMD7 36
  • 44 (a)
(Danio rerio)
Actinopterygii samd7 36
  • 29 (a)
fruit fly
(Drosophila melanogaster)
Insecta Samuel 36
  • 8 (a)
Species with no ortholog for SAMD7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SAMD7 Gene

Gene Tree for SAMD7 (if available)
Gene Tree for SAMD7 (if available)

Paralogs for SAMD7 Gene

Paralogs for SAMD7 Gene

genes like me logo Genes that share paralogs with SAMD7: view

Variants for SAMD7 Gene

Sequence variations from dbSNP and Humsavar for SAMD7 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs4955694 -- 169,915,088(+) cataa(C/T)ccata intron-variant, upstream-variant-2KB
rs4572818 -- 169,913,023(+) TAAGA(A/G)AAGGC intron-variant
rs4353844 -- 169,913,021(+) CCTAA(A/G)AGAAG intron-variant
rs4256179 -- 169,910,541(+) GTTAC(A/G)TGATT upstream-variant-2KB
rs3902131 -- 169,910,681(-) GTAAC(C/T)ATATT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SAMD7 Gene

Variant ID Type Subtype PubMed ID
nsv7356 OTHER Inversion 18451855
nsv460987 CNV Loss 19166990
esv2663940 CNV Deletion 23128226
esv2726188 CNV Deletion 23290073
nsv877976 CNV Gain 21882294

Relevant External Links for SAMD7 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SAMD7 Gene

Disorders for SAMD7 Gene

No disorders were found for SAMD7 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for SAMD7 Gene

Publications for SAMD7 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4
  3. Sterile alpha motif containing 7 (samd7) is a novel crx-regulated transcriptional repressor in the retina. (PMID: 23565263) Hlawatsch J. … Langmann T. (PLoS ONE 2013) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for SAMD7 Gene

Sources for SAMD7 Gene

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