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Aliases for SAMD5 Gene

Aliases for SAMD5 Gene

  • Sterile Alpha Motif Domain Containing 5 2 3
  • SAM Domain-Containing Protein 5 3 4
  • Sterile Alpha Motif Domain-Containing Protein 5 3
  • SAM Domain Containing 1 3
  • DJ875H10.1 3
  • SAMDC1 4

External Ids for SAMD5 Gene

Previous GeneCards Identifiers for SAMD5 Gene

  • GC00U914193
  • GC06U900641
  • GC06P147873
  • GC06P145393

Summaries for SAMD5 Gene

GeneCards Summary for SAMD5 Gene

SAMD5 (Sterile Alpha Motif Domain Containing 5) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SAMD5 Gene

Genomics for SAMD5 Gene

Regulatory Elements for SAMD5 Gene

Genomic Location for SAMD5 Gene

Start:
147,508,692 bp from pter
End:
147,737,547 bp from pter
Size:
228,856 bases
Orientation:
Plus strand

Genomic View for SAMD5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SAMD5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SAMD5 Gene

Proteins for SAMD5 Gene

  • Protein details for SAMD5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5TGI4-SAMD5_HUMAN
    Recommended name:
    Sterile alpha motif domain-containing protein 5
    Protein Accession:
    Q5TGI4
    Secondary Accessions:

    Protein attributes for SAMD5 Gene

    Size:
    173 amino acids
    Molecular mass:
    19231 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SAMD5 Gene

Proteomics data for SAMD5 Gene at MOPED

Post-translational modifications for SAMD5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SAMD5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SAMD5 Gene

Domains for SAMD5 Gene

Gene Families for SAMD5 Gene

HGNC:
  • SAMD :Sterile alpha motif (SAM) domain containing

Protein Domains for SAMD5 Gene

Suggested Antigen Peptide Sequences for SAMD5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5TGI4

UniProtKB/Swiss-Prot:

SAMD5_HUMAN :
  • Q5TGI4
Domain:
  • Contains 1 SAM (sterile alpha motif) domain.
genes like me logo Genes that share domains with SAMD5: view

Function for SAMD5 Gene

Gene Ontology (GO) - Molecular Function for SAMD5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with SAMD5: view

miRNA for SAMD5 Gene

miRTarBase miRNAs that target SAMD5

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for SAMD5 Gene

Localization for SAMD5 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SAMD5 Gene COMPARTMENTS Subcellular localization image for SAMD5 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for SAMD5 Gene

Pathways for SAMD5 Gene

SuperPathways for SAMD5 Gene

No Data Available

Interacting Proteins for SAMD5 Gene

Gene Ontology (GO) - Biological Process for SAMD5 Gene

None

No data available for Pathways by source for SAMD5 Gene

Transcripts for SAMD5 Gene

mRNA/cDNA for SAMD5 Gene

(70) Selected AceView cDNA sequences:
(1) Additional mRNA sequences :
(2) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SAMD5 Gene

Sterile alpha motif domain containing 5:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SAMD5 Gene

No ASD Table

Relevant External Links for SAMD5 Gene

GeneLoc Exon Structure for
SAMD5
ECgene alternative splicing isoforms for
SAMD5

Expression for SAMD5 Gene

mRNA expression in normal human tissues for SAMD5 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SAMD5 Gene

This gene is overexpressed in Esophagus - Mucosa (6.2), Kidney - Cortex (5.2), and Liver (4.5).

SOURCE GeneReport for Unigene cluster for SAMD5 Gene Hs.567973

genes like me logo Genes that share expressions with SAMD5: view

No data available for Protein expression and mRNA Expression by UniProt/SwissProt for SAMD5 Gene

Orthologs for SAMD5 Gene

This gene was present in the common ancestor of animals.

Orthologs for SAMD5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SAMD5 35
  • 99.42 (n)
  • 98.84 (a)
SAMD5 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SAMD5 35
  • 92.1 (n)
  • 90.17 (a)
SAMD5 36
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Samd5 35
  • 87.6 (n)
  • 90.7 (a)
Samd5 16
Samd5 36
  • 90 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SAMD5 36
  • 71 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SAMD5 36
  • 83 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Samd5 35
  • 87.86 (n)
  • 91.33 (a)
chicken
(Gallus gallus)
Aves SAMD5 36
  • 89 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SAMD5 36
  • 62 (a)
OneToOne
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.3472 35
zebrafish
(Danio rerio)
Actinopterygii LOC100148561 35
  • 59.23 (n)
  • 62.16 (a)
SAMD5 36
  • 52 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG34377 36
  • 16 (a)
OneToMany
SKIP 36
  • 7 (a)
OneToMany
Species with no ortholog for SAMD5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SAMD5 Gene

ENSEMBL:
Gene Tree for SAMD5 (if available)
TreeFam:
Gene Tree for SAMD5 (if available)

Paralogs for SAMD5 Gene

No data available for Paralogs for SAMD5 Gene

Variants for SAMD5 Gene

Sequence variations from dbSNP and Humsavar for SAMD5 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs471833 -- 147,517,279(+) ttcca(A/G)ttgaa intron-variant
rs472577 -- 147,515,082(+) CGTTC(A/G)TGACA intron-variant
rs480456 -- 147,526,387(+) AATTA(C/T)AGTCT intron-variant
rs494234 -- 147,524,170(+) TATAC(C/T)TACCT intron-variant
rs494395 -- 147,513,691(+) AAAGC(A/G)AAAGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SAMD5 Gene

Variant ID Type Subtype PubMed ID
esv2662219 CNV Deletion 23128226
nsv819870 CNV Gain 19587683

Relevant External Links for SAMD5 Gene

HapMap Linkage Disequilibrium report
SAMD5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SAMD5 Gene

Disorders for SAMD5 Gene

Relevant External Links for SAMD5

Genetic Association Database (GAD)
SAMD5
genes like me logo Genes that share disorders with SAMD5: view

No data available for UniProtKB/Swiss-Prot for SAMD5 Gene

Publications for SAMD5 Gene

  1. Common genetic variation and the control of HIV-1 in humans. (PMID: 20041166) Fellay J. … Goldstein D.B. (PLoS Genet. 2009) 3 48
  2. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3
  3. Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project. (PMID: 17903300) Fox C.S. … Atwood L.D. (BMC Med. Genet. 2007) 48
  4. Genome-wide scan of copy number variation in late-onset Alzheimer's disease. (PMID: 20061627) Heinzen E.L. … Goldstein D.B. (J. Alzheimers Dis. 2010) 48
  5. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 4

Products for SAMD5 Gene

Sources for SAMD5 Gene

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