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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SAMD4A Gene

protein-coding   GIFtS: 52
GCID: GC14P055034

Sterile Alpha Motif Domain Containing 4A

(Previous name: sterile alpha motif domain containing 4)
(Previous symbol: SAMD4)
Microbiology & Infectious Diseases Congress
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Sterile Alpha Motif Domain Containing 4A1 2     SMAUG2
SAMD41 2 3     SMG2
SMAUG12 3 5     SMGA2
SAM Domain-Containing Protein 4A2 3     Protein Smaug Homolog 12
KIAA10533 5     hSmaug13
Smaug Homolog (Drosophila)1     Smaug 13
Sterile Alpha Motif Domain Containing 41     Sterile Alpha Motif Domain-Containing Protein 4A3

External Ids:    HGNC: 230231   Entrez Gene: 230342   Ensembl: ENSG000000205777   OMIM: 6107475   UniProtKB: Q9UPU93   

Export aliases for SAMD4A gene to outside databases

Previous GC identifers: GC14P054105 GC14P035197


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SAMD4A Gene:
Sterile alpha motifs (SAMs) in proteins such as SAMD4A are part of an RNA-binding domain that functions as a
posttranscriptional regulator by binding to an RNA sequence motif known as the Smaug recognition element, which
was named after the Drosophila Smaug protein (Baez and Boccaccio, 2005 (PubMed 16221671)).(supplied by OMIM, Mar
2008)

GeneCards Summary for SAMD4A Gene: 
SAMD4A (sterile alpha motif domain containing 4A) is a protein-coding gene. Diseases associated with SAMD4A include prostatitis. GO annotations related to this gene include translation repressor activity. An important paralog of this gene is SAMD4B.

UniProtKB/Swiss-Prot: SMAG1_HUMAN, Q9UPU9
Function: Acts as a translational repressor of SRE-containing messengers




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NT_026437.12  NC_018925.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SAMD4A gene promoter:
         Max1   SRF   USF1   SRF (504 AA)   Pax-2   Pax-2a   USF-1   ZID   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSAMD4A promoter sequence
   Search SABiosciences Chromatin IP Primers for SAMD4A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SAMD4A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q22.2   Ensembl cytogenetic band:  14q22.2   HGNC cytogenetic band: 14q22.2

SAMD4A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SAMD4A gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P055034:  view genomic region     (about GC identifiers)

Start:
55,033,815 bp from pter      End:
55,260,033 bp from pter
Size:
226,219 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SMAG1_HUMAN, Q9UPU9 (See protein sequence)
Recommended Name: Protein Smaug homolog 1  
Size: 718 amino acids; 79415 Da
Subcellular location: Cytoplasm. Cell projection, dendrite (By similarity). Cell junction, synapse, synaptosome
(By similarity). Note=Enriched in synaptoneurosomes (By similarity). Shuttles between the nucleus and the
cytoplasm in a CRM1-dependent manner. Colocalizes throughout the cytoplasm in granules with polyadenylated RNAs,
PABPC1 and STAU1. Also frequently colocalizes in cytoplasmic stress granule-like foci with ELAVL1, TIA1 and TIAL1
Sequence caution: Sequence=AAH57838.1; Type=Miscellaneous discrepancy; Note=Intron retention; Sequence=AAP97302.1;
Type=Miscellaneous discrepancy; Note=Intron retention;
Secondary accessions: A8MPZ5 Q0VA96 Q6PEW4
Alternative splicing: 3 isoforms:  Q9UPU9-1   Q9UPU9-2   Q9UPU9-3   

Explore the universe of human proteins at neXtProt for SAMD4A: NX_Q9UPU9

Explore proteomics data for SAMD4A at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9UPU9

  • SAMD4A Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SAMD4A Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001155048.2  NP_001155049.1  NP_056404.4  

    ENSEMBL proteins: 
     ENSP00000452535   ENSP00000251091   ENSP00000450808   ENSP00000375919   ENSP00000350261  

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    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0030054cell junction IEA--
    GO:0030425dendrite IEA--
    GO:0045202synapse IEA--

    SAMD4A for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SAMD: Sterile alpha motif (SAM) domain containing

    4 InterPro protein domains:
     IPR013761 SAM/pointed
     IPR001660 SAM
     IPR015327 Smaug_PHAT
     IPR021129 SAM_type1

    Graphical View of Domain Structure for InterPro Entry Q9UPU9

    ProtoNet protein and cluster: Q9UPU9

    1 Blocks protein domain: IPB001660 Sterile alpha motif SAM

    UniProtKB/Swiss-Prot: SMAG1_HUMAN, Q9UPU9
    Similarity: Belongs to the SMAUG family
    Similarity: Contains 1 SAM (sterile alpha motif) domain


    SAMD4A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SMAG1_HUMAN, Q9UPU9
    Function: Acts as a translational repressor of SRE-containing messengers

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0030371translation repressor activity IDA16221671
         
    SAMD4A for ontologies           About GeneDecksing


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    SwitchGear 3'UTR luciferase reporter plasmidSAMD4A 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SAMD4A

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    5 Interacting proteins for SAMD4A (Q9UPU92, 3 ENSP000003502614) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    YWHAGP619812, 3, ENSP000003063304MINT-50895 I2D: score=3 STRING: ENSP00000306330
    SFNP319472, 3MINT-3976569 I2D: score=1 
    PAFAH1B1P430343I2D: score=4 
    THP071013I2D: score=3 
    BICD1Q96G013I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0017148negative regulation of translation IDA16221671
    GO:0045727positive regulation of translation IDA16221671

    SAMD4A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SAMD4A (SMAG1)

    Search CenterWatch for drugs/clinical trials and news about SAMD4A / SMAG1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SAMD4A gene (3 alternative transcripts): 
    NM_001161576.2  NM_001161577.1  NM_015589.5  

    Unigene Clusters for SAMD4A:

    Sterile alpha motif domain containing 4A
    Hs.98259  [show with all ESTs], Hs.733324  [show with all ESTs]
    Unigene Representative Sequences: NM_015589, BX648198
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000554335 ENST00000251091(uc001xbb.3 uc001xbc.3) ENST00000555112(uc001xba.3 uc001xbe.3)
    ENST00000555091 ENST00000557692 ENST00000557013(uc001xbf.2) ENST00000554587
    ENST00000555192 ENST00000556069 ENST00000553988 ENST00000555719 ENST00000392067
    ENST00000357634(uc001xbg.2)
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    8/141 QIAGEN miScript miRNA Assays for microRNAs that regulate SAMD4A (see all 141):
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    SwitchGear 3'UTR luciferase reporter plasmidSAMD4A 3' UTR sequence
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    Additional mRNA sequence: BX648198.1 

    14 DOTS entries:

    DT.316734  DT.92427239  DT.97841245  DT.100787078  DT.101974729  DT.91915383  DT.86849225  DT.120756214 
    DT.40119306  DT.92427240  DT.95181273  DT.91740892  DT.95180363  DT.95181288 

    24/175 AceView cDNA sequences (see all 175):

    BU634138 NM_015589 AB028976 AI090923 BM054954 AA622908 AA377422 BC021726 
    AA235435 CA407556 BM128739 BQ213310 F09903 BI829225 AI190545 AI299604 
    AK024652 BX118663 BU193631 AA411889 AA464602 BX471435 CD370605 AW955792 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for SAMD4A (see all 9)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16a · 16b ^
    SP1:              -     -     -     -     -     -     -     -     -                 -     -     -                             -                                 
    SP2:                                                                                -     -     -     -     -                 -                                 
    SP3:                                                                                                                                                            
    SP4:                                                                                -     -                                                                     
    SP5:                                -                                                                                                                           

    ExUns: 17 ^ 18a · 18b ^ 19 ^ 20a · 20b
    SP1:        -     -                     
    SP2:        -     -                     
    SP3:              -                     
    SP4:                                    
    SP5:                                    


    ECgene alternative splicing isoforms for SAMD4A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SAMD4A expression in normal human tissues (normalized intensities)      SAMD4A embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCTATATTTC
    SAMD4A Expression
    About this image


    SAMD4A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/5 selected tissues (see all 5) fully expand
     
     Testis (Reproductive System)    fully expand to see all 3 entries
             Leydig Cells Testis Interstitium
             Testis Interstitium
     
     Lung (Respiratory System)
             Basal Cells Respiratory Bronchioles
     
     Ovary (Reproductive System)
             Cumulus Cells Antral Follicle
     
     Blood (Hematopoietic System)
             Proerythroblasts Hematopoietic Bone Marrow
     
     Heart (Cardiovascular System)

    See SAMD4A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SAMD4A

    SOURCE GeneReport for Unigene clusters: Hs.98259 Hs.733324
        SABiosciences Custom PCR Arrays for SAMD4A
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SAMD4A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SAMD4A gene from 7/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Samd41 , 5 sterile alpha motif domain containing 41, 5 92.63(n)1
    96.34(a)1
      14 (24.41 cM)5
    744801  NM_001037221.21  NP_001032298.11 
     468828545 
    chicken
    (Gallus gallus)
    Aves SAMD4A1 sterile alpha motif domain containing 4A 84.16(n)
    88.09(a)
      423559  XM_421450.3  XP_421450.2 
    lizard
    (Anolis carolinensis)
    Reptilia SAMD4A6
    Uncharacterized protein
    85(a)
    1 ↔ 1
    GL343533.1(300058-450479)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.201602 Transcribed sequence with moderate similarity to protein more 78.96(n)    BX755234.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1001498581 protein Smaug homolog 1-like 69.25(n)
    72.73(a)
      100149858  XM_001920663.2  XP_001920698.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta smg6
    smaug
    14(a)
    1 → many
    3L(8983417-8991089)
    worm
    (Caenorhabditis elegans)
    Secernentea ZC190.46
    Protein ZC190.4
    14(a)
    1 → many
    V(8666065-8670969)


    ENSEMBL Gene Tree for SAMD4A (if available)
    TreeFam Gene Tree for SAMD4A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SAMD4A gene
    SAMD4B2  
    2 SIMAP similar genes for SAMD4A using alignment to 4 protein entries:     SMAG1_HUMAN (see all proteins):
    DKFZp434H0350    SAMD4B

    SAMD4A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/4779 SNPs in SAMD4A are shown (see all 4779)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs722339931,2
    C--35231731(+) AAAAT-/ACACACACACA
    CACACACACACAC
    ACACA
    2 -- int10--------
    rs569003471,2
    C--36122066(+) TTTTT-/T/T   
       T
    /TTT
    CTTCA
    2 -- int11NA 2
    rs1892425391,2
    --55032837(+) TCCGCA/GAGCCG 2 -- us2k10--------
    rs1472112041,2
    --55032999(+) AGGGCC/TCCCGA 2 -- us2k10--------
    rs128887091,2
    --55033050(+) TACGGC/G/TCCTCG 2 -- us2k10--------
    rs1406130761,2
    --55033195(+) CCCGCC/TGGCGG 2 -- us2k10--------
    rs1162642491,2
    C,F--55033955(+) CAGCCG/TTTGGC 2 -- us2k11Minor allele frequency- T:0.01WA 118
    rs45487931,2
    C,F,H--55034066(+) GGAGGG/AGGCGG 2 -- us2k116Minor allele frequency- A:0.16NS EA NA CSA WA 1966
    rs2010073091,2
    C--55034152(+) CCTCG-/CCCCCC 2 -- us2k10--------
    rs601478601,2
    C--55034377(+) TCGTTA/-TTTTT 2 -- ut512Minor allele frequency- -:0.25CSA 4

    HapMap Linkage Disequilibrium report for SAMD4A (55033815 - 55260033 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for SAMD4A:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2670707CNV Deletion23128226
    esv1004703CNV Deletion20482838
    esv2675932CNV Deletion23128226
    nsv1282CNV Insertion18451855
    nsv436788CNV Insertion17901297
    nsv832802CNV Loss17160897


    Human Gene Mutation Database (HGMD): SAMD4A
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing SAMD4A
    DNA2.0 Custom Variant and Variant Library Synthesis for SAMD4A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610747    OMIM disorders: --

    2 diseases for SAMD4A:    About MalaCards
    prostatitis    


    SAMD4A for disorders           About GeneDecksing

    Genetic Association Database (GAD): SAMD4A
    Human Genome Epidemiology (HuGE) Navigator: SAMD4A (4 documents)

    Export disorders for SAMD4A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SAMD4A gene, integrated from 9 sources (see all 24):
    (articles sorted by number of sources associating them with SAMD4A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Mammalian Smaug is a translational repressor that forms cytoplasmic foci similar to stress granules. (PubMed id 16221671)1, 2, 3 Baez M.V. and Boccaccio G.L. (2005)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    3. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    4. Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10470851)1, 2 Kikuno R....Ohara O. (1999)
    5. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (2012)
    6. Smaug1 mRNA-silencing foci respond to NMDA and modula te synapse formation. (PubMed id 22201125)1 Baez M.V....Boccaccio G.L. (2011)
    7. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
    8. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
    9. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (2007)
    10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23034 HGNC: 23023 AceView: SAMD4 Ensembl:ENSG00000020577 euGenes: HUgn23034
    ECgene: SAMD4A H-InvDB: SAMD4A

    (According to HUGE)
    About This Section
    HUGE: KIAA1053

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SAMD4A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SAMD4A gene:
    Search GeneIP for patents involving SAMD4A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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