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Aliases for SAMD3 Gene

Aliases for SAMD3 Gene

  • Sterile Alpha Motif Domain Containing 3 2 3
  • SAM Domain-Containing Protein 3 4

External Ids for SAMD3 Gene

Previous GeneCards Identifiers for SAMD3 Gene

  • GC06M130446
  • GC06M130507
  • GC06M130465
  • GC06M128046

Summaries for SAMD3 Gene

GeneCards Summary for SAMD3 Gene

SAMD3 (Sterile Alpha Motif Domain Containing 3) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SAMD3 Gene

Genomics for SAMD3 Gene

Regulatory Elements for SAMD3 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SAMD3 Gene

130,144,302 bp from pter
130,365,425 bp from pter
221,124 bases
Minus strand

Genomic View for SAMD3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SAMD3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SAMD3 Gene

Proteins for SAMD3 Gene

  • Protein details for SAMD3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Sterile alpha motif domain-containing protein 3
    Protein Accession:
    Secondary Accessions:
    • B4DY20
    • E1P576
    • J3KQK4
    • Q4VXD8
    • Q8NAY1
    • Q8NB96

    Protein attributes for SAMD3 Gene

    520 amino acids
    Molecular mass:
    61237 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SAMD3 Gene


neXtProt entry for SAMD3 Gene

Proteomics data for SAMD3 Gene at MOPED

Post-translational modifications for SAMD3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for SAMD3 Gene

Domains for SAMD3 Gene

Gene Families for SAMD3 Gene

Protein Domains for SAMD3 Gene

Suggested Antigen Peptide Sequences for SAMD3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 SAM (sterile alpha motif) domain.
  • Contains 1 SAM (sterile alpha motif) domain.
genes like me logo Genes that share domains with SAMD3: view

Function for SAMD3 Gene

Gene Ontology (GO) - Molecular Function for SAMD3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 23455924
genes like me logo Genes that share ontologies with SAMD3: view

Animal Model Products

miRNA for SAMD3 Gene

miRTarBase miRNAs that target SAMD3

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SAMD3

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for SAMD3 Gene

Localization for SAMD3 Gene

Subcellular locations from

Jensen Localization Image for SAMD3 Gene COMPARTMENTS Subcellular localization image for SAMD3 gene
Compartment Confidence
cytosol 2
mitochondrion 2
nucleus 2
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for SAMD3 Gene

Pathways for SAMD3 Gene

SuperPathways for SAMD3 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SAMD3 Gene


No data available for Pathways by source for SAMD3 Gene

Transcripts for SAMD3 Gene

Unigene Clusters for SAMD3 Gene

Sterile alpha motif domain containing 3:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SAMD3

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SAMD3 Gene

ExUns: 1 ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14
SP1: - - - -
SP3: -

Relevant External Links for SAMD3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SAMD3 Gene

mRNA expression in normal human tissues for SAMD3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SAMD3 Gene

This gene is overexpressed in Whole Blood (16.9) and Spleen (4.6).

Protein differential expression in normal tissues for SAMD3 Gene

This gene is overexpressed in Plasma (64.4).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for SAMD3 Gene

SOURCE GeneReport for Unigene cluster for SAMD3 Gene Hs.440508

genes like me logo Genes that share expressions with SAMD3: view

Expression partners for SAMD3 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for SAMD3 Gene

Orthologs for SAMD3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SAMD3 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SAMD3 35
  • 90.78 (n)
  • 89.02 (a)
BT.47533 36
  • 89 (a)
(Canis familiaris)
Mammalia SAMD3 35
  • 86.07 (n)
  • 81.59 (a)
SAMD3 36
  • 80 (a)
(Mus musculus)
Mammalia Samd3 35
  • 84.5 (n)
  • 81.91 (a)
Samd3 16
Samd3 36
  • 82 (a)
(Pan troglodytes)
Mammalia SAMD3 35
  • 99.42 (n)
  • 99.23 (a)
SAMD3 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Samd3 35
  • 84.37 (n)
  • 82.78 (a)
(Monodelphis domestica)
Mammalia SAMD3 36
  • 77 (a)
(Ornithorhynchus anatinus)
Mammalia SAMD3 36
  • 64 (a)
(Gallus gallus)
Aves SAMD3 35
  • 67.23 (n)
  • 62.58 (a)
SAMD3 36
  • 60 (a)
Species with no ortholog for SAMD3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SAMD3 Gene

Gene Tree for SAMD3 (if available)
Gene Tree for SAMD3 (if available)

Paralogs for SAMD3 Gene

No data available for Paralogs for SAMD3 Gene

Variants for SAMD3 Gene

Sequence variations from dbSNP and Humsavar for SAMD3 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs468924 -- 130,325,392(+) cggca(C/G)gagat intron-variant
rs468868 -- 130,338,432(+) cacta(G/T)ggcac intron-variant
rs468656 -- 130,298,423(+) ccata(A/T)aagca intron-variant
rs468644 -- 130,328,361(+) ACCTA(G/T)AGGCT intron-variant
rs468008 -- 130,285,011(+) ACTGT(C/G)CCAAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SAMD3 Gene

Variant ID Type Subtype PubMed ID
esv2677571 CNV Deletion 23128226

Relevant External Links for SAMD3 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SAMD3 Gene

Disorders for SAMD3 Gene

Relevant External Links for SAMD3

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for SAMD3 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for SAMD3 Gene

Publications for SAMD3 Gene

  1. Many sequence variants affecting diversity of adult human height. (PMID: 18391951) Gudbjartsson D.F. … Stefansson K. (Nat. Genet. 2008) 3 48
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for SAMD3 Gene

Sources for SAMD3 Gene

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