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Aliases for SAMD14 Gene

Aliases for SAMD14 Gene

  • Sterile Alpha Motif Domain Containing 14 2 3
  • SAM Domain-Containing Protein 14 4

External Ids for SAMD14 Gene

Previous GeneCards Identifiers for SAMD14 Gene

  • GC17M045544
  • GC17M048188
  • GC17M043557

Summaries for SAMD14 Gene

GeneCards Summary for SAMD14 Gene

SAMD14 (Sterile Alpha Motif Domain Containing 14) is a Protein Coding gene. Diseases associated with SAMD14 include lung adenoma. An important paralog of this gene is PPP1R9A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SAMD14 Gene

Genomics for SAMD14 Gene

Regulatory Elements for SAMD14 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SAMD14 Gene

Start:
50,110,040 bp from pter
End:
50,129,882 bp from pter
Size:
19,843 bases
Orientation:
Minus strand

Genomic View for SAMD14 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SAMD14 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SAMD14 Gene

Proteins for SAMD14 Gene

  • Protein details for SAMD14 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IZD0-SAM14_HUMAN
    Recommended name:
    Sterile alpha motif domain-containing protein 14
    Protein Accession:
    Q8IZD0
    Secondary Accessions:
    • A5D8V1
    • Q8N2X0

    Protein attributes for SAMD14 Gene

    Size:
    417 amino acids
    Molecular mass:
    45056 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SAMD14 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SAMD14 Gene

Proteomics data for SAMD14 Gene at MOPED

Post-translational modifications for SAMD14 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SAMD14 Gene

No data available for DME Specific Peptides for SAMD14 Gene

Domains for SAMD14 Gene

Gene Families for SAMD14 Gene

HGNC:
  • SAMD :Sterile alpha motif (SAM) domain containing

Protein Domains for SAMD14 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for SAMD14 Gene

Graphical View of Domain Structure for InterPro Entry

Q8IZD0

UniProtKB/Swiss-Prot:

SAM14_HUMAN :
  • Q8IZD0
Domain:
  • Contains 1 SAM (sterile alpha motif) domain.
genes like me logo Genes that share domains with SAMD14: view

Function for SAMD14 Gene

Gene Ontology (GO) - Molecular Function for SAMD14 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with SAMD14: view

Animal Model Products

CRISPR Products

miRNA for SAMD14 Gene

miRTarBase miRNAs that target SAMD14

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SAMD14

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for SAMD14 Gene

Localization for SAMD14 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SAMD14 Gene COMPARTMENTS Subcellular localization image for SAMD14 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for SAMD14 Gene

Pathways for SAMD14 Gene

SuperPathways for SAMD14 Gene

No Data Available

Interacting Proteins for SAMD14 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000424474%0d%0a9606.ENSP00000354837%0d%0a9606.ENSP00000411459%0d%0a
Selected Interacting proteins: ENSP00000424474 for SAMD14 Gene via STRING

Gene Ontology (GO) - Biological Process for SAMD14 Gene

None

No data available for Pathways by source for SAMD14 Gene

Transcripts for SAMD14 Gene

Unigene Clusters for SAMD14 Gene

Sterile alpha motif domain containing 14:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SAMD14

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for SAMD14

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SAMD14 Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b
SP1: - - - - - -
SP2: - - - - - - -
SP3: - - -
SP4: - -
SP5: - - - - -
SP6:
SP7:
SP8: -

Relevant External Links for SAMD14 Gene

GeneLoc Exon Structure for
SAMD14
ECgene alternative splicing isoforms for
SAMD14

Expression for SAMD14 Gene

mRNA expression in normal human tissues for SAMD14 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SAMD14 Gene

This gene is overexpressed in Brain - Cerebellum (7.3) and Brain - Cerebellar Hemisphere (6.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for SAMD14 Gene

SOURCE GeneReport for Unigene cluster for SAMD14 Gene Hs.567769

genes like me logo Genes that share expressions with SAMD14: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for SAMD14 Gene

Orthologs for SAMD14 Gene

This gene was present in the common ancestor of animals.

Orthologs for SAMD14 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SAMD14 35
  • 99.48 (n)
  • 98.88 (a)
SAMD14 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SAMD14 35
  • 91.13 (n)
  • 95.92 (a)
SAMD14 36
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SAMD14 35
  • 92.25 (n)
  • 97.36 (a)
SAMD14 36
  • 77 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Samd14 35
  • 88.25 (n)
  • 94.48 (a)
Samd14 16
Samd14 36
  • 94 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SAMD14 36
  • 87 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SAMD14 36
  • 62 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Samd14 35
  • 88.49 (n)
  • 94.96 (a)
chicken
(Gallus gallus)
Aves SAMD14 35
  • 70.95 (n)
  • 67.89 (a)
SAMD14 36
  • 61 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SAMD14 36
  • 72 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii LOC100537418 35
  • 53.02 (n)
  • 50.86 (a)
SAMD14 36
  • 39 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta Spn 36
  • 4 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea nab-1 36
  • 11 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 10 (a)
OneToOne
Species with no ortholog for SAMD14:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for SAMD14 Gene

ENSEMBL:
Gene Tree for SAMD14 (if available)
TreeFam:
Gene Tree for SAMD14 (if available)

Paralogs for SAMD14 Gene

Paralogs for SAMD14 Gene

Selected SIMAP similar genes for SAMD14 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with SAMD14: view

Variants for SAMD14 Gene

Sequence variations from dbSNP and Humsavar for SAMD14 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs705967 -- 50,118,634(-) CAGAC(C/G)TTAAA intron-variant
rs739499 -- 50,118,550(-) ATCAC(A/C)CGGCG intron-variant
rs739500 -- 50,118,454(-) TCTGT(A/G)CTCCC intron-variant
rs847681 -- 50,131,329(-) catgt(A/G)atcca upstream-variant-2KB
rs847682 -- 50,130,910(-) TCTTC(A/G)GTGTC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SAMD14 Gene

Variant ID Type Subtype PubMed ID
nsv908588 CNV Loss 21882294
nsv908590 CNV Loss 21882294
dgv3225n71 CNV Loss 21882294
dgv3226n71 CNV Loss 21882294
dgv3227n71 CNV Loss 21882294
esv1003562 CNV Loss 20482838

Relevant External Links for SAMD14 Gene

HapMap Linkage Disequilibrium report
SAMD14

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SAMD14 Gene

Disorders for SAMD14 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for SAMD14 Gene including...

Search for SAMD14 Gene in MalaCards »

(1) University of Copenhagen DISEASES for SAMD14 Gene

genes like me logo Genes that share disorders with SAMD14: view

No data available for UniProtKB/Swiss-Prot for SAMD14 Gene

Publications for SAMD14 Gene

  1. A "double adaptor" method for improved shotgun library construction. (PMID: 8619474) Andersson B. … Gibbs R.A. (Anal. Biochem. 1996) 2 3
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3
  5. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PMID: 8125298) Maruyama K. … Sugano S. (Gene 1994) 3

Products for SAMD14 Gene

Sources for SAMD14 Gene

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