V3 here soon-try beta now
Gene Search (GeneCards Home) | GeneCards Guide | User Feedback | Terms of Use | Notice about third-party sites
 

SAMD13 Gene

protein-coding   GIFtS: 40

GC01P084536
sterile alpha motif domain containing 13
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    

Aliases &
Descriptions
for SAMD13

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
OTTHUMP00000011476 2
RP11-376N17.1 2
Descriptions
dnaj-like protein (LOC148418) 2
sterile alpha motif domain containing 13 2
External Ids
HGNC: 245821
Entrez Gene: 1484182
UniProtKB: Q5VXD33
Ensembl: ENSG000002039437
Search outside databases for aliases for SAMD13 gene

Previous GC identifer: GC01P084477

Summaries
for SAMD13

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

   --

Genomic Location
for SAMD13

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the SAMD13 gene  

Entrez Gene cytogenetic band: 1p31.1   Ensembl cytogenetic band:  1p31.1   HGNC cytogenetic band: 1p31.1

SAMD13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P084536:     (about GC identifiers)

Start:
 84,536,633 bp from pter
End:
 84,589,067 bp from pter
Size:
 52,435 bases
Orientation:
 plus strand
RefSeq DNA sequence:
NC_000001.9  NT_032977.8  

Proteins
for SAMD13

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: SAM13_HUMAN, Q5VXD3 (See protein sequence)
Recommended Name: Sterile alpha motif domain-containing protein 13  
Size: 122 amino acids; 13570 Da
Secondary accessions: Q53AI4 Q5VXD2 Q5VXD4
Alternative splicing: 3 isoforms:  Q5VXD3-1   Q5VXD3-2   Q5VXD3-3   

REFSEQ proteins (3 alternative transcripts): 
NP_001010971.1  NP_001128135.1  NP_001128136.1  


ENSEMBL proteins: 
ENSP00000359701 ENSP00000359702 ENSP00000359703 ENSP00000359704 ENSP00000359705 ENSP00000359707 
ENSP00000378311 


Human Recombinant Proteins 
Browse Drug Discovery Central at Invitrogen for human recombinant proteins
Browse Purified and Recombinant Proteins at Millipore
Browse Human Recombinant Proteins at Sigma-Aldrich  
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
Browse Abcam for Recombinant Proteins
Browse Abnova for Human Recombinant Proteins
                Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 


Antibodies for SAMD13: 
Browse Antibodies Central at Invitrogen
Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Browse Antibodies at Sigma-Aldrich
Browse R&D Systems for Antibodies
Search for antibodies at Abcam and the World's Antibody Gateway (free search engine of over 150 antibody companies)
Browse Abnova for Monoclonal and Polyclonal Antibodies
Search Novus for antibodies for SAMD13

Assays for SAMD13: 
Browse Invitrogen for biochemical assays
Browse Kits and Assays available from Millipore
Browse R&D Systems for biochemical assays
Browse biochemical assays available from Enzo Life Sciences

Protein Domains/
Families
for SAMD13

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
2 InterPro domains/families:
 IPR013761 SAM_type
 IPR001660 SAM


   GeneDecks  SAMD13 for the domains selected above  
About GeneDecksing

Graphical View of Domain Structure for InterPro Entry Q5VXD3

ProtoNet protein and cluster: Q5VXD3

1 Blocks protein family: IPB001660 Sterile alpha motif SAM

UniProtKB/Swiss-Prot: SAM13_HUMAN, Q5VXD3
Similarity: Contains 1 SAM (sterile alpha motif) domain

Gene Function
for SAMD13

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section
Inhib.
RNA:		Invitrogen RNAi Products for gene knock-down (SAMD13)
Browse for Gene Knock-down Tools from Millipore
Browse Abnova for Chimera RNAi Products
               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4): XM_086188

              Applied Biosystems Silencer® siRNAs for SAMD13

              Sigma-Aldrich siRNA for SAMD13  
                     Sigma-Aldrich shRNA for SAMD13  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Clones:Browse Clone Ranger at Invitrogen for clones
Browse Clones for the Expression of Recombinant Proteins Available from Millipore
               OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_001010971
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_001010971
                                 untagged cDNA clones in CMV expression vector (see all 3): NM_001010971 

Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
              OriGene genome-wide validated SYBR primer pairs: NM_001010971

Pathways & Interactions
for SAMD13

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section


  --

Drugs & Compounds
for SAMD13

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences
Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for SAMD13

Transcripts
for SAMD13

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section
Inhib.
RNA:		Invitrogen RNAi Products for gene knock-down (SAMD13)
Browse for Gene Knock-down Tools from Millipore
Browse Abnova for Chimera RNAi Products
               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4): XM_086188

              Sigma-Aldrich siRNA for SAMD13  
                     Sigma-Aldrich shRNA for SAMD13  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Applied Biosystems Silencer® siRNAs: 

NM_001010971  NM_001134663  NM_001134664  

REFSEQ mRNAs for SAMD13 gene (3 alternative transcripts): 

NM_001010971.2   NM_001134663.1   NM_001134664.1   

Applied Biosystems TaqMan ® Gene Expression Assays: 

NM_001010971  NM_001134663  NM_001134664  

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_001010971
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_001010971
                                 untagged cDNA clones in CMV expression vector (see all 3): NM_001010971 

Additional cDNA sequence: 

AK056937.1 AK311207.1 AY604569.1 AY604570.1 BC037973.1 CR615899.1 CR617905.1 

6 DOTS entries:

DT.408382  DT.100016382  DT.65287831  DT.121454623  DT.99999749  DT.303134 

24/41 AceView cDNA sequences (see all 41 ):

BX092540 CK821789 BX281193 CD107636 CR615899 AA913464 BC037973 CR617905 
CK821788 BI759190 BX325328 BM926925 CB047557 BU853107 AI696679 AA846694 
BU680318 AI631824 AA609154 AA812514 AA465293 AW262750 BF000472 AA496252 

highest scoring ESTs for SAMD13:

AI631824 AA465293 AA491039 AA496252 AA812514 AA846694 AA913464 AI219980 AI696679 AK056937 

Unigene Cluster for SAMD13:

Sterile alpha motif domain containing 13
Hs.591445  [show with all ESTs]
Unigene Representative Sequence: NM_001010971


GeneLoc Exon Structure

7 Ensembl transcripts including schematic representations:
ENST00000370667  ENST00000370668  ENST00000370669  ENST00000370670  ENST00000370671  ENST00000370673  
ENST00000394834  

Expression
for SAMD13

(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

SAMD13 expression in normal and diseased human tissues

 Applied Biosystems TaqMan ® Gene Expression Assays for SAMD13

1 / 2 / 3

3 probe-sets matching SAMD13 gene


Affymetrix
probe-set		 Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
58113_at2, 3 U95-B 1 1.00 1.00 1.00 1.00 AI631824 1.00 1.00 1.00 1

229402_at2, 3 U133-B 1 1.00 1.00 -- -- AI631824 1.00 1.00 1.00 1

229402_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
GeneDecks  SAMD13 for binary patterns associated with the probe-sets selected above  
About GeneDecksing
About this table    
Data from (Publications) and GNF BioGPS
    About these images
About these images

CGAP SAGE TAG: ATGGTGTAAT

SOURCE GeneReport for Unigene cluster: Hs.591445

Orthologs
for SAMD13

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section
Orthologs for SAMD13 gene from 5/6 species (see all 6 )
Organism Gene Locus Description Human
Similarity		 NCBI accessions
dog
(Canis familiaris)		 SAMD131   -- sterile alpha motif domain containing 13 94.5(n)
98.97(a)		 479974  XM_537098.2  XP_537098.2 
chimpanzee
(Pan troglodytes)		 SAMD131   -- sterile alpha motif domain containing 13 99.71(n)
100(a)		 456976  XM_513519.2  XP_513519.2 
cow
(Bos taurus)		 SAMD131   -- sterile alpha motif domain containing 13 93.81(n)
96.91(a)		 614782  XM_866638.2  XP_871731.1 
mouse
(Mus musculus)		 Samd135 3 sterile alpha motif domain containing 13   -- -
zebrafish
(Danio rerio)		 zgc:1533761   -- zgc:153376 73.54(n)
80.41(a)		 767772  NM_001076739.1  NP_001070207.1 
About this table        Species with no ortholog for SAMD13

ENSEMBL Gene Tree for SAMD13

Paralogs
for SAMD13

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section

Paralogs for SAMD13 gene
SAMD12  

SNPs/Variants
for SAMD13

(According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section


10/233 NCBI SNPs in SAMD13 are shown (see all 233 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 100)
ABGenomic DataTranscription DataAllele Frequencies
SNP IDValidChr 1 posSequenceRecsAA
Chg		TypeMoreRecsAllele
freq		PopTotal
sample		More
------------
rs3155401,2
A,C,F,H84589175(+) TGGGGC/AAAAAA 1 -- ng314Minor allele frequency- A:0.18EU EA WA 388
--
rs8686121,2
A,C,F,H84535541(-) GTTATC/TTACTA 1 -- ng517Minor allele frequency- T:0.11EU EA WA NA 542
rs12465741,2
C,F,H84534685(+) gcaccA/Ggacgt 1 -- ng514Minor allele frequency- G:0.11EU EA WA 414
rs171316171,2
F,H84588056(+) TCAAAT/CTGGGG 3 -- ut317Minor allele frequency- C:0.02NA EU EA WA 560
rs171316181,2
F,H84588659(+) GCTCCG/ATTGTG 3 -- ut317Minor allele frequency- A:0.02NA EU EA WA 562
rs8141521,2
F,H84588711(-) ATATCA/GTTACC 3 -- ut315Minor allele frequency- G:0.01MN EU EA WA 604
rs66895981,2
F,H84588170(+) GAAACG/ATTATC 3 -- ut31 ese34Minor allele frequency- A:0.01EU EA WA 420
rs175364731,2
F,H84588836(+) AGGTCA/CAAAAG 3 -- ut31 ese37Minor allele frequency- C:0.03NA EU EA WA 562
--
rs7848341,2
A84535001(+) gatcaC/Tagatc 1 -- ng510--------
--
rs125645151,2
C84535206(+) ctgcaA/Gtaaag 1 -- ng51 tfbs30--------
About this table

HapMap Linkage Disequilibrium images for SAMD13 (up to first 250kb)

Disorders & Mutations
for SAMD13

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

   --

Medical News
for SAMD13

(Possibly Related Articles in Doctor's Guide)
About This Section

   --

Publications
for SAMD13

(in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
About This Section

4 PubMed articles for SAMD13 gene:

Search for SAMD13

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

 ANDOR
Aliases
Free Text  
  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

Genome Databases showing SAMD13

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section
Entrez Gene: 148418 HGNC: 24582 AceView: LOC148418 Ensembl:ENSG00000203943 euGenes: HUgn148418
ECgene: SAMD13 H-InvDB: SAMD13

Other Databases showing SAMD13

(According to HUGE)
About This Section

   --

Specialized Databases showing SAMD13

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

   --

Licensable Technologies
for SAMD13

(Available from WIS Yeda, Salk, Tufts)
About This Section

  --

Services
for SAMD13

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section



Products for SAMD13:
 TaqMan ® Gene Expression Assays
 TaqMan ® Genotyping Assays
  Free SNP selection tool



  Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
  Invitrogen Antibodies  Invitrogen Assays
  Invitrogen Clones  Invitrogen Q-PCR Products
  Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
  Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for SAMD13-related products

 Millipore Custom Antibody & Bulk Services
 Millipore Preclinical / Clinical Development Services
 Millipore Immunoassay Services
 Millipore Target Screening & Profiling Services


 Predesigned and custom siRNAs for SAMD13 Browse antibodies at Sigma-Aldrich
 Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
 Lentivirus-delivered shRNAs for SAMD13 Browse small molecules at Sigma-Aldrich
 "Your Favorite Gene" Pathwaysfeedback


  
 Antibodies   Primer Pairs  
 Cell Culture Products   ELISAs  
 Flow Cytometry Kits   Protease Activity Assays & Reagents  
 Cell Selection/Detection Kits & Reagents   ELISA/Assay Development Kits & Reagents  
 Multiplex/Array Assay Kits & Reagents   ELISpot Kits & Development Modules  
 Recombinant & Natural Proteins  

 Search for Recombinant Proteins
 Search for Antibodies
 Search for Chimera RNAi
 Custom Service for Mouse Mab
 Custom Service for Rabbit Pab from Full-length Protein
  
 Search for Antibodies & Assays

 Search for Recombinant Proteins
 Search for Antibodies
 Search OriGene for SAMD13
 Search Tocris compounds for SAMD13




 Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
 Search Novus for antibodies for SAMD13

GeneCards Homepage    -    Last full update: 1 Jul 2009        Incremental update: 13 Oct 2009

Random Gene From GIFtS : about GIFtS

Gene Index:   3   5   A   B   C   D   E   F   G   H   I   J   K   L   M   N   O   P   Q   R   S   T   U   V   W   X   Y   Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science



The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
SAMD13 Gene at Home site.
Version 2.41.1
server5.xennexinc.com