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SAMD11 Gene

protein-coding   GIFtS: 43
GCID: GC01P000860

Sterile Alpha Motif Domain Containing 11

  Search for SAMD11
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Sterile Alpha Motif Domain Containing 111 2     Sterile Alpha Motif Domain Containing 11 Splice Variant ASV32
SAM Domain-Containing Protein 112 3     Sterile Alpha Motif Domain Containing 11 Splice Variant ASV302
Sterile Alpha Motif Domain Containing 11 Splice Variant ASV12     Sterile Alpha Motif Domain Containing 11 Splice Variant ASV312
Sterile Alpha Motif Domain Containing 11 Splice Variant ASV102     Sterile Alpha Motif Domain Containing 11 Splice Variant ASV322
Sterile Alpha Motif Domain Containing 11 Splice Variant ASV112     Sterile Alpha Motif Domain Containing 11 Splice Variant ASV332
Sterile Alpha Motif Domain Containing 11 Splice Variant ASV122     Sterile Alpha Motif Domain Containing 11 Splice Variant ASV342
Sterile Alpha Motif Domain Containing 11 Splice Variant ASV132     Sterile Alpha Motif Domain Containing 11 Splice Variant ASV352
Sterile Alpha Motif Domain Containing 11 Splice Variant ASV142     Sterile Alpha Motif Domain Containing 11 Splice Variant ASV362
Sterile Alpha Motif Domain Containing 11 Splice Variant ASV152     Sterile Alpha Motif Domain Containing 11 Splice Variant ASV372
Sterile Alpha Motif Domain Containing 11 Splice Variant ASV162     Sterile Alpha Motif Domain Containing 11 Splice Variant ASV382
Sterile Alpha Motif Domain Containing 11 Splice Variant ASV172     Sterile Alpha Motif Domain Containing 11 Splice Variant ASV392
Sterile Alpha Motif Domain Containing 11 Splice Variant ASV182     Sterile Alpha Motif Domain Containing 11 Splice Variant ASV42
Sterile Alpha Motif Domain Containing 11 Splice Variant ASV192     Sterile Alpha Motif Domain Containing 11 Splice Variant ASV402
Sterile Alpha Motif Domain Containing 11 Splice Variant ASV22     Sterile Alpha Motif Domain Containing 11 Splice Variant ASV412
Sterile Alpha Motif Domain Containing 11 Splice Variant ASV202     Sterile Alpha Motif Domain Containing 11 Splice Variant ASV422
Sterile Alpha Motif Domain Containing 11 Splice Variant ASV212     Sterile Alpha Motif Domain Containing 11 Splice Variant ASV432
Sterile Alpha Motif Domain Containing 11 Splice Variant ASV222     Sterile Alpha Motif Domain Containing 11 Splice Variant ASV442
Sterile Alpha Motif Domain Containing 11 Splice Variant ASV232     Sterile Alpha Motif Domain Containing 11 Splice Variant ASV452
Sterile Alpha Motif Domain Containing 11 Splice Variant ASV242     Sterile Alpha Motif Domain Containing 11 Splice Variant ASV52
Sterile Alpha Motif Domain Containing 11 Splice Variant ASV252     Sterile Alpha Motif Domain Containing 11 Splice Variant ASV62
Sterile Alpha Motif Domain Containing 11 Splice Variant ASV262     Sterile Alpha Motif Domain Containing 11 Splice Variant ASV72
Sterile Alpha Motif Domain Containing 11 Splice Variant ASV272     Sterile Alpha Motif Domain Containing 11 Splice Variant ASV82
Sterile Alpha Motif Domain Containing 11 Splice Variant ASV282     Sterile Alpha Motif Domain Containing 11 Splice Variant ASV92
Sterile Alpha Motif Domain Containing 11 Splice Variant ASV292     Sterile Alpha Motif Domain-Containing Protein 112

External Ids:    HGNC: 287061   Entrez Gene: 1483982   Ensembl: ENSG000001876347   UniProtKB: Q96NU13   

Export aliases for SAMD11 gene to outside databases

Previous GC identifers: GC01P000914 GC01P000850 GC01P000132


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SAMD11 Gene:
SAMD11 (sterile alpha motif domain containing 11) is a protein-coding gene. GO annotations related to this gene include protein self-association and SAM domain binding. An important paralog of this gene is PHC1.

UniProtKB/Swiss-Prot: SAM11_HUMAN, Q96NU1
Function: May play a role in photoreceptor development (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NC_018912.2  NT_032977.10  
Regulatory elements:
   Search for regulatory transcription factor binding sites for SAMD11
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSAMD11 promoter sequence
   Search Chromatin IP Primers for SAMD11

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SAMD11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.33   Ensembl cytogenetic band:  1p36.33   HGNC cytogenetic band: 1p36.33

SAMD11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SAMD11 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P000860:  view genomic region     (about GC identifiers)

Start:
860,260 bp from pter      End:
879,961 bp from pter
Size:
19,702 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SAM11_HUMAN, Q96NU1 (See protein sequence)
Recommended Name: Sterile alpha motif domain-containing protein 11  
Size: 681 amino acids; 72708 Da
Subunit: Homodimer (By similarity)
Sequence caution: Sequence=BAB70781.1; Type=Erroneous initiation; Sequence=CAI15563.3; Type=Erroneous gene model
prediction; Sequence=CAI15564.3; Type=Erroneous gene model prediction;
Secondary accessions: A2AA76 I7FV78 I7FV81 I7G0Z6 Q5SV96 Q5SV99 Q5SVA0 Q8N195 Q8TB59
Alternative promoter usage, Alternative splicing: 6 isoforms:  Q96NU1-3   Q96NU1-1   Q96NU1-2   Q96NU1-4   Q96NU1-5   Q96NU1-6   (Produced by alternative splicing)

Explore the universe of human proteins at neXtProt for SAMD11: NX_Q96NU1

Explore proteomics data for SAMD11 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SAMD11 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_689699.2  
    ENSEMBL proteins: 
     ENSP00000411579   ENSP00000393181   ENSP00000342313   ENSP00000349216   ENSP00000412228  

    SAMD11 Human Recombinant Protein Products:

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    Browse Sino Biological Cell Lysates
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    Search LSBio for Antibodies for SAMD11

    SAMD11 Assay Products:

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    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SAMD: Sterile alpha motif (SAM) domain containing

    3 InterPro protein domains:
     IPR013761 SAM/pointed
     IPR001660 SAM
     IPR011510 SAM_2

    Graphical View of Domain Structure for InterPro Entry Q96NU1

    ProtoNet protein and cluster: Q96NU1

    2 Blocks protein domains:
    IPB001660 Sterile alpha motif SAM
    IPB011510 Sterile alpha motif homology 2


    UniProtKB/Swiss-Prot: SAM11_HUMAN, Q96NU1
    Similarity: Contains 1 SAM (sterile alpha motif) domain


    SAMD11 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SAM11_HUMAN, Q96NU1
    Function: May play a role in photoreceptor development (By similarity)

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0032093SAM domain binding IEA--
    GO:0042731PH domain binding IEA--
    GO:0043621protein self-association IEA--
         
    SAMD11 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SAMD11
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SAMD11

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SAMD11
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SAMD11

    miRNA
    Products:
        
    miRTarBase miRNAs that target SAMD11:
    hsa-mir-124-3p (MIRT022194), hsa-mir-375 (MIRT019690)

    Block miRNA regulation of human, mouse, rat SAMD11 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate SAMD11:
    hsa-miR-504
    SwitchGear 3'UTR luciferase reporter plasmidSAMD11 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SAMD11
    Predesigned siRNA for gene silencing in human, mouse, rat SAMD11

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SAMD11

    Clone
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    OriGene clones in human, mouse for SAMD11 (see all 6)
    OriGene ORF clones in mouse, rat for SAMD11
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SAMD11 (NM_152486)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SAMD11
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SAMD11

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for SAMD11 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SAMD11


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SAM11_HUMAN, Q96NU1: Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2
    mitochondrion1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    SAMD11 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SAMD11
    Interactions:

        Search GeneGlobe Interaction Network for SAMD11

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IEA--

    SAMD11 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SAMD11 (SAM11)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SAMD11 gene: 
    NM_152486.2  

    Unigene Cluster for SAMD11:

    Sterile alpha motif domain containing 11
    Hs.335293  [show with all ESTs]
    Unigene Representative Sequence: NM_152486
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000420190(uc001abv.1) ENST00000437963 ENST00000342066(uc001abw.1)
    ENST00000341065(uc001abx.1) ENST00000455979 ENST00000478729 ENST00000474461
    ENST00000466827 ENST00000464948
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SAMD11 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate SAMD11:
    hsa-miR-504
    SwitchGear 3'UTR luciferase reporter plasmidSAMD11 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SAMD11
    Predesigned siRNA for gene silencing in human, mouse, rat SAMD11
    Clone
    Products:
         
    OriGene clones in human, mouse for SAMD11 (see all 6)
    OriGene ORF clones in mouse, rat for SAMD11
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SAMD11 (NM_152486)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SAMD11
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SAMD11
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for SAMD11
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat SAMD11
      QuantiTect SYBR Green Assays in human, mouse, rat SAMD11
      QuantiFast Probe-based Assays in human, mouse, rat SAMD11

    Additional mRNA sequence: 

    BC024295.2 BC033213.1 JX093066.1 JX093067.1 JX093068.1 JX093069.1 JX093070.1 JX093071.1 
    JX093072.1 JX093073.1 JX093074.1 JX093075.1 JX093076.1 JX093077.1 JX093078.1 JX093079.1 
    JX093080.1 JX093081.1 JX093082.1 JX093083.1 JX093084.1 JX093085.1 JX093086.1 JX093087.1 
    JX093088.1 JX093089.1 JX093090.1 JX093091.1 JX093092.1 JX093093.1 JX093094.1 JX093095.1 
    JX093096.1 JX093097.1 JX093098.1 JX093099.1 JX093100.1 JX093101.1 JX093102.1 JX093103.1 
    JX093104.1 JX093105.1 JX093106.1 JX093107.1 JX093108.1 JX093109.1 JX093110.1 

    9 DOTS entries:

    DT.100812602  DT.92449043  DT.431656  DT.100812601  DT.91667087  DT.100812599  DT.40125956  DT.97855405 
    DT.121329402 

    Selected AceView cDNA sequences (see all 69):

    BM708219 CA396407 CA389330 CK820075 BQ070703 BQ670036 BM052997 BU732060 
    CD672892 BM055344 BM055062 BQ636129 BU955824 NM_152486 BM876236 BU688963 
    BM972064 BM876494 BM273155 AW473561 AI765077 BC024295 BE515227 AI681255 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for SAMD11    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b · 10c
    SP1:              -                                                                           
    SP2:                                                                                          
    SP3:                                                                                          
    SP4:                                                                          -               
    SP5:                                                                                          


    ECgene alternative splicing isoforms for SAMD11

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SAMD11 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGAAAAATA
    SAMD11 Expression
    About this image


    SAMD11 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Neural Crest (Gastrulation Derivatives)
             PureStem 7SMOO32, NCr-fac & Meso Progenitor
     
     Adipose (Muscoskeletal System)
             HyStem+BMP4-induced SM30 cells
     
     Bone (Muscoskeletal System)
             HyStem+BMP4-induced SM30 cells
     
     Mesoderm (Gastrulation Derivatives)
             PureStem 7SMOO32, NCr-fac & Meso Progenitor
     
     Blood (Hematopoietic System)
             Proerythroblasts Hematopoietic Bone Marrow
    SAMD11 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SAMD11 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.335293
        Custom PCR Arrays for SAMD11
    Primer
    Products:
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SAMD11

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SAMD11 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Samd111 , 5 sterile alpha motif domain containing 111, 5 77.24(n)1
    73.73(a)1
      45
    2310041  NM_001110516.11  NP_001103986.11 
     1562469735 
    chicken
    (Gallus gallus)
    Aves SAMD111 sterile alpha motif domain containing 11 68.15(n)
    62.06(a)
      419434  NM_001030877.1  NP_001026048.1 
    lizard
    (Anolis carolinensis)
    Reptilia SAMD116
    sterile alpha motif domain containing 11
    44(a)
    1 ↔ 1
    GL343334.1(672918-708986)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ039981.12   -- 75.14(n)    BJ039981.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.111612 Transcribed sequence with weak similarity to protein more 72.06(n)    57095892 
    fruit fly
    (Drosophila melanogaster)
    Insecta Samuel6
    SAM-motif ubiquitously expressed punctatedly local...
    11(a)
    1 → many
    2L(11013221-11066997)


    ENSEMBL Gene Tree for SAMD11 (if available)
    TreeFam Gene Tree for SAMD11 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SAMD11 gene
    PHC12  PHC32  PHC22  SAMD72  
    3 SIMAP similar genes for SAMD11 using alignment to 40 protein entries:     SAM11_HUMAN (see all proteins):
    HPH1    PHC3    SAMD13

    SAMD11 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for SAMD11
    PGOHUM00000236902


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SAMD11 (see all 657)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1885349881,2
    --859206(+) CCGCCA/GGATGC 1 -- us2k10--------
    rs715094441,2
    C--859404(+) ACCCCG/CGAGAG 1 -- us2k13Minor allele frequency- C:0.00NA 6
    rs1115727041,2
    C,F--859685(+) CCGGGG/ACGCAC 1 -- us2k11Minor allele frequency- A:0.50NA 2
    rs715094451,2
    C,F--859690(+) GCGCAG/CTAGCG 1 -- us2k11Minor allele frequency- C:0.00NA 2
    rs715094461,2
    C--859701(+) GACGGG/CGTGGG 1 -- us2k11Minor allele frequency- C:0.00NA 2
    rs1127039631,2
    C,F--859913(+) CTGCCG/AGGCTA 1 -- us2k11Minor allele frequency- A:0.03NA 120
    rs285464611,2
    C--860045(+) CACGAG/TGCCGC 1 -- us2k11Minor allele frequency- T:0.00NA 2
    rs614644281,2
    C--860416(+) GGCTCG/AGCCGA 1 -- us2k15Minor allele frequency- A:0.45NA CSA WA EA 361
    rs574651181,2
    C,F--860461(+) CCCCCA/GCCGCG 1 -- us2k16Minor allele frequency- G:0.41NA CSA WA EA 364
    rs780330731,2
    C,F--860504(+) CCCCCG/ACTGCA 1 -- us2k11Minor allele frequency- A:0.14EA 120

    HapMap Linkage Disequilibrium report for SAMD11 (860260 - 879961 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for SAMD11 (see all 24):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1732269CNV Deletion17803354
    esv2723916CNV Deletion23290073
    esv1062785CNV Deletion17803354
    esv2722805CNV Deletion23290073
    esv2663451CNV Deletion23128226
    esv2066434CNV Deletion18987734
    esv2721694CNV Deletion23290073
    nsv509035CNV Insertion20534489
    dgv8n71CNV Loss21882294
    dgv9n71CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SAMD11 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with SAMD11)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of novel alternative splice variants of human SAMD11. (PubMed id 23978614)1, 2 Jin G....Shen H. (Gene 2013)
    2. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    6. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (Nat. Biotechnol. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 148398 HGNC: 28706 AceView: SAMD11 Ensembl:ENSG00000187634 euGenes: HUgn148398
    ECgene: SAMD11 H-InvDB: SAMD11

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for SAMD11 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for SAMD11 gene:
    Search GeneIP for patents involving SAMD11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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