SAMD10 Gene
protein-coding GIFtS: 39
GCID: GC20M062605
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sterile alpha motif domain containing 10(Previous name: chromosome 20 open reading frame 136 )
(Previous symbol: C20orf136)
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Aliases
for SAMD10 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Sterile Alpha Motif Domain Containing 101 2 | | D930033N23Rik2 | | C20orf1361 2 3 | | DJ591C201 | | SAM Domain-Containing Protein 102 3 | | DJ591C20.71 | | Chromosome 20 Open Reading Frame 1361 | | Sterile Alpha Motif Domain-Containing Protein 102 |
Export aliases for SAMD10 gene to outside databasesPrevious GC identifers: GC20M062075 GC20M059340 |
Summaries
for SAMD10 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for SAMD10 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011333.6
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SAMD10 gene promoter:
STAT1 p53 Brachyury STAT1beta HNF-4alpha2 Nkx2-5 STAT1alpha HNF-4alpha1 PPAR-gamma1 HFH-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for SAMD10
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SAMD10 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20q13.33 Ensembl cytogenetic band: 20q13.33 HGNC cytogenetic band: 20q13.33SAMD10 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20M062605: view genomic region
(about GC identifiers)
Start:
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62,605,466 bp from pter |
End:
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62,611,361 bp from pter |
Size:
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5,896 bases |
Orientation:
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minus strand |
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Proteins
for SAMD10 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SAM10_HUMAN, Q9BYL1 (See
protein sequence)Recommended Name: Sterile alpha motif domain-containing protein 10 Size: 202 amino acids; 22770 DaExplore the universe of human proteins at neXtProt for SAMD10: NX_Q9BYL1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9BYL1
SAMD10 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_542188.1
ENSEMBL proteins: ENSP00000358902 ENSP00000404839
Human Recombinant Protein Products:
SAMD10 Antibody Products:
Assay Products for SAMD10: |
Protein
Domains /
Families
for SAMD10 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SAMD10 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9BYL1ProtoNet protein and cluster: Q9BYL1 2 Blocks protein families: IPB001660 Sterile alpha motif SAM IPB011510 Sterile alpha motif homology 2
UniProtKB/Swiss-Prot: SAM10_HUMAN, Q9BYL1Similarity: Contains 1 SAM (sterile alpha motif) domain |
Function
for SAMD10 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SAMD10 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SAMD10
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for SAMD10 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SAMD10 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SAMD10 |
|
Pathways & Interactions
for SAMD10 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SAMD10
|
Drugs & Compounds
for SAMD10 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SAMD10
Search CenterWatch for drugs/clinical trials and news about SAMD10 / SAM10
|
Transcripts
for SAMD10 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SAMD10 gene: NM_080621.4 Unigene Cluster for SAMD10: Sterile alpha motif domain containing 10 Hs.27189 [show with all ESTs]Unigene Representative Sequence: BC0673624 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000369886(uc002yhm.2 uc002yhn.2) ENST00000498830 ENST00000478694
ENST00000450107
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SAMD10 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SAMD10
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SAMD10 (NM_080621) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SAMD10 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SAMD10 |
Additional cDNA sequence: BC041436.1 BC067362.1 5 DOTS entries: DT.100775448 DT.92068341 DT.92068340 DT.95163039 DT.97832303 24/161 AceView cDNA sequences (see all 161): BQ102387 BM761742 BI792939 BM126579 BM846832 AA085380 BC067362 AI768920 BC041436 BX344567 BE858902 AW276028 BE563161 CA848672 AI567790 AL834525 BM712657 BM713680 AA886921 BI964067 AW136926 NM_020713 BM068760 BU526555
GeneLoc Exon Structure
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Expression
for SAMD10 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SAMD10 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGAAGTAAAG
About this image
See SAMD10 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SAMD10
SOURCE GeneReport for Unigene cluster: Hs.27189
SABiosciences Custom PCR Arrays for SAMD10
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SAMD10
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SAMD10 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SAMD10 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SAMD10 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SAMD10 |
Orthologs
for SAMD10 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of animals.
Orthologs for SAMD10 gene from 5/15 species (see all 15) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
SAMD101 |
sterile alpha motif domain containing 10 |
80.49(n)
79.88(a) |
|
428153 XM_425711.2 XP_425711.2 |
lizard
(Anolis carolinensis) |
Reptilia |
SAMD106 |
-- |
75(a) |
1 ↔ 1 |
4(155753906-155783839) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.143132 |
Xenopus laevis transcribed sequence with weak similarity more |
71.73(n) |
|
BX848353.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
samd10b1 |
sterile alpha motif domain containing 10b |
71.51(n)
67.44(a) |
|
100147927 XM_001922974.1 XP_001923009.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
ave6 |
aveugle |
29(a) |
1 → many |
2R(10640031-10640774) |
ENSEMBL Gene Tree for SAMD10 (if available)
TreeFam Gene Tree for SAMD10 (if available) |
Paralogs
for SAMD10 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SAMD10 gene
- SAMD122
1 SIMAP similar gene for SAMD10 using alignment to 2 protein entries: SAM10_HUMAN (see all proteins):SAMD12
SAMD10 for paralogs About GeneDecksing
|
Genomic Variants
for SAMD10 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 20 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SAMD10 (62605466 - 62611361 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for SAMD10
2 CNVs: 2252 31047 | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for SAMD10 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for SAMD10 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SAMD10 gene integrated from 9 sources:
(articles sorted by number of sources associating them with SAMD10) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
- Transcriptome analysis of human gastric cancer. (PubMed id 16341674)1 Oh J.H....Kim N.S. (2005)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for SAMD10 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing SAMD10 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SAMD10 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SAMD10 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SAMD10 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for SAMD10 gene:
Search GeneIP for patents involving SAMD10
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SAMD10 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SAMD10 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SAMD10 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SAMD10 | | | OriGene Protein Over-expression Lysate for SAMD10 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SAMD10 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SAMD10 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SAMD10 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | | Search Tocris compounds for SAMD10 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SAMD10 |
|  |  |  | | | | Search ThermoFisher Antibodies for SAMD10 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SAMD10 |
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