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Aliases for SAMD10 Gene

Aliases for SAMD10 Gene

  • Sterile Alpha Motif Domain Containing 10 2 3 5
  • SAM Domain-Containing Protein 10 3 4
  • C20orf136 3 4
  • Sterile Alpha Motif Domain-Containing Protein 10 3
  • Chromosome 20 Open Reading Frame 136 2
  • D930033N23Rik 3
  • DJ591C20.7 3
  • DJ591C20 3

External Ids for SAMD10 Gene

Previous HGNC Symbols for SAMD10 Gene

  • C20orf136

Previous GeneCards Identifiers for SAMD10 Gene

  • GC20M062075
  • GC20M062605
  • GC20M059340

Summaries for SAMD10 Gene

GeneCards Summary for SAMD10 Gene

SAMD10 (Sterile Alpha Motif Domain Containing 10) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is SAMD12.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SAMD10 Gene

Genomics for SAMD10 Gene

Regulatory Elements for SAMD10 Gene

Enhancers for SAMD10 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around SAMD10 on UCSC Golden Path with GeneCards custom track

Promoters for SAMD10 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for SAMD10 Gene

63,974,113 bp from pter
63,980,986 bp from pter
6,874 bases
Minus strand

Genomic View for SAMD10 Gene

Genes around SAMD10 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SAMD10 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SAMD10 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SAMD10 Gene

Proteins for SAMD10 Gene

  • Protein details for SAMD10 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Sterile alpha motif domain-containing protein 10
    Protein Accession:

    Protein attributes for SAMD10 Gene

    202 amino acids
    Molecular mass:
    22770 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SAMD10 Gene

Post-translational modifications for SAMD10 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SAMD10 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SAMD10 Gene

Domains & Families for SAMD10 Gene

Gene Families for SAMD10 Gene

Protein Domains for SAMD10 Gene

Suggested Antigen Peptide Sequences for SAMD10 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 SAM (sterile alpha motif) domain.
  • Contains 1 SAM (sterile alpha motif) domain.
genes like me logo Genes that share domains with SAMD10: view

Function for SAMD10 Gene

Phenotypes for SAMD10 Gene

genes like me logo Genes that share phenotypes with SAMD10: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SAMD10 Gene

Localization for SAMD10 Gene

Subcellular locations from

Jensen Localization Image for SAMD10 Gene COMPARTMENTS Subcellular localization image for SAMD10 gene
Compartment Confidence
nucleus 3
cytosol 1
extracellular 1
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for SAMD10 Gene

Pathways & Interactions for SAMD10 Gene

SuperPathways for SAMD10 Gene

No Data Available

Interacting Proteins for SAMD10 Gene

Selected Interacting proteins: Q9BYL1-SAM10_HUMAN for SAMD10 Gene via IID

Gene Ontology (GO) - Biological Process for SAMD10 Gene


No data available for Pathways by source and SIGNOR curated interactions for SAMD10 Gene

Drugs & Compounds for SAMD10 Gene

No Compound Related Data Available

Transcripts for SAMD10 Gene

Unigene Clusters for SAMD10 Gene

Sterile alpha motif domain containing 10:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SAMD10 Gene

No ASD Table

Relevant External Links for SAMD10 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SAMD10 Gene

mRNA expression in normal human tissues for SAMD10 Gene

mRNA differential expression in normal tissues according to GTEx for SAMD10 Gene

This gene is overexpressed in Brain - Cerebellum (x4.1).

Protein differential expression in normal tissues from HIPED for SAMD10 Gene

This gene is overexpressed in Tlymphocyte (64.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SAMD10 Gene

Protein tissue co-expression partners for SAMD10 Gene

NURSA nuclear receptor signaling pathways regulating expression of SAMD10 Gene:


SOURCE GeneReport for Unigene cluster for SAMD10 Gene:

genes like me logo Genes that share expression patterns with SAMD10: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for SAMD10 Gene

Orthologs for SAMD10 Gene

This gene was present in the common ancestor of animals.

Orthologs for SAMD10 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SAMD10 34
  • 90.43 (n)
  • 92.08 (a)
SAMD10 35
  • 92 (a)
(Canis familiaris)
Mammalia SAMD10 34
  • 91.25 (n)
  • 95.05 (a)
SAMD10 35
  • 95 (a)
(Mus musculus)
Mammalia Samd10 34
  • 89.27 (n)
  • 92.08 (a)
Samd10 16
Samd10 35
  • 92 (a)
(Pan troglodytes)
Mammalia SAMD10 34
  • 99.83 (n)
  • 100 (a)
SAMD10 35
  • 100 (a)
(Rattus norvegicus)
Mammalia Samd10 34
  • 89.6 (n)
  • 93.07 (a)
(Monodelphis domestica)
Mammalia SAMD10 35
  • 85 (a)
(Ornithorhynchus anatinus)
Mammalia SAMD10 35
  • 69 (a)
(Gallus gallus)
Aves SAMD10 34
  • 79.92 (n)
  • 79.53 (a)
SAMD10 35
  • 75 (a)
(Anolis carolinensis)
Reptilia SAMD10 35
  • 61 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.14313 34
(Danio rerio)
Actinopterygii samd10b 34
  • 70.76 (n)
  • 66.67 (a)
samd10a 35
  • 51 (a)
samd10b 35
  • 66 (a)
fruit fly
(Drosophila melanogaster)
Insecta ave 35
  • 31 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 28 (a)
Species where no ortholog for SAMD10 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SAMD10 Gene

Gene Tree for SAMD10 (if available)
Gene Tree for SAMD10 (if available)

Paralogs for SAMD10 Gene

Paralogs for SAMD10 Gene

(1) SIMAP similar genes for SAMD10 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with SAMD10: view

Variants for SAMD10 Gene

Sequence variations from dbSNP and Humsavar for SAMD10 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs1046513 -- 63,974,683(-) TGGGC(C/T)TTCCC utr-variant-3-prime
rs817339 -- 63,974,631(+) GCCCT(A/G)GGAAG utr-variant-3-prime
rs817340 -- 63,974,671(+) GAAAG(A/C)AGCAA utr-variant-3-prime
rs817341 -- 63,975,412(+) CATCC(C/T)GCAGG utr-variant-3-prime
rs817342 -- 63,975,620(+) CTCCT(A/G)AGGTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SAMD10 Gene

Variant ID Type Subtype PubMed ID
nsv1160691 CNV deletion 26073780
nsv428381 CNV gain+loss 18775914
nsv469773 CNV gain 16826518
nsv509784 CNV insertion 20534489
nsv586703 CNV loss 21841781
nsv953309 CNV deletion 24416366
nsv9830 CNV gain 18304495

Variation tolerance for SAMD10 Gene

Residual Variation Intolerance Score: 39.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.45; 28.45% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SAMD10 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SAMD10 Gene

Disorders for SAMD10 Gene

Relevant External Links for SAMD10

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SAMD10 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SAMD10 Gene

Publications for SAMD10 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 65
  2. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3 4 65
  3. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. (PMID: 23535732) Eeles R.A. … Easton D.F. (Nat. Genet. 2013) 3 65
  4. Transcriptome analysis of human gastric cancer. (PMID: 16341674) Oh J.H. … Kim N.S. (Mamm. Genome 2005) 3 65
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 65

Products for SAMD10 Gene

Sources for SAMD10 Gene

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