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Aliases &
Descriptions
for SAMD1
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| | | Descriptions |
|---|
| SAM domain containing 1 2 | | Sterile alpha motif domain-containing protein 1 3 | | sterile alpha motif domain containing 1 2 |
|
| |
Search outside databases for aliases for SAMD1 genePrevious GC identifer: GC19U990301 |
Summaries
for SAMD1(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: SAMD1_HUMAN, Q6SPF0Function: May play a role in atherogenesis by immobilizing LDL in the atherial wall |
Genomic Location
for SAMD1
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences)
About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
 Transcription factor binding sites upstream to the SAMD1 gene 
Entrez Gene cytogenetic band: 19p13.12 Ensembl cytogenetic band: 19p13.12 HGNC cytogenetic band: 19p13.13SAMD1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M014062:
(about GC identifiers)
Start:
|
14,059,676 bp from pter |
End:
|
14,062,885 bp from pter |
Size:
|
3,210 bases |
Orientation:
|
minus strand |
RefSeq DNA sequence:- NC_000019.8 NT_011295.10
| Proteins
for SAMD1
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: SAMD1_HUMAN, Q6SPF0 (See
protein sequence)Recommended Name: Atherin Size: 538 amino acids; 56052 Da
Subcellular location: Cytoplasm. Secreted
Secondary accessions: Q6P0R3 Q6PIS7 Q96IM4Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_612361.1
ENSEMBL proteins: ENSP00000269724 ENSP00000380611
Human Recombinant Proteins  Browse Origene for full length recombinant human proteins expressed in human HEK293 cells
2 Gene Ontology (GO) cellular component terms (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005576 | extracellular region |
IEA | -- | | GO:0005737 | cytoplasm |
IEA | -- |
About this table
Antibodies for SAMD1:
Assays for SAMD1: | Protein
Domains/
Families
for SAMD1(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q6SPF0
ProtoNet protein and cluster: Q6SPF0 1 Blocks protein family: IPB001660 Sterile alpha motif SAM
UniProtKB/Swiss-Prot: SAMD1_HUMAN, Q6SPF0Similarity: Contains 1 SAM (sterile alpha motif) domain | Gene Function
for SAMD1
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_138352
 Applied Biosystems Silencer® siRNAs for SAMD1
 Sigma-Aldrich siRNA for SAMD1
Sigma-Aldrich shRNA for SAMD1
Explore Sigma-Aldrich super-pooled esiRNAs
OriGene GFP tagged cDNA clone in CMV expression vector: NM_138352
Myc/DDK tagged cDNA clone in CMV expression vector: NM_138352
untagged cDNA clones in CMV expression vector (see all 2): NM_138352
Primers:  Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
OriGene genome-wide validated SYBR primer pairs: NM_138352
UniProtKB/Swiss-Prot: SAMD1_HUMAN, Q6SPF0Function: May play a role in atherogenesis by immobilizing LDL in the atherial wall | Pathways & Interactions
for SAMD1
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
-- |
Drugs & Compounds
for SAMD1(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for SAMD1
|
Transcripts
for SAMD1(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene,
Expression Assays from Applied Biosystems)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_138352
Sigma-Aldrich siRNA for SAMD1
Sigma-Aldrich shRNA for SAMD1
Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer® siRNAs: NM_138352 REFSEQ mRNAs for SAMD1 gene: NM_138352.1
Applied Biosystems TaqMan ® Gene Expression Assays: NM_138352
OriGene GFP tagged cDNA clone in CMV expression vector: NM_138352
Myc/DDK tagged cDNA clone in CMV expression vector: NM_138352
untagged cDNA clones in CMV expression vector (see all 2): NM_138352
Additional cDNA sequence: AY453840.1 BC007384.2 BC030129.2 BC065477.1 BC080588.1 CR607932.1 7 DOTS entries: DT.97781471 DT.454102 DT.99983488 DT.100812555 DT.100812556 DT.415619 DT.95272179 24/167 AceView cDNA sequences (see all 167
):BC065477 AW236552 AI199022 AI186973 AA132083 N45729 BM840318 CR607932 BM842690 CA449494 BE746961 AI569682 AA029172 AI271358 BU735933 BF058975 AI379283 AI674176 BM792162 AA682370 AI470106 AA471046 AI660679 AI123580
 highest scoring ESTs for SAMD1:AA029068 AA341319 AA649303 AA743778 AA765474 AA766034 AA766164 AA769505 AA804533 AA806888 Unigene Cluster for SAMD1: Sterile alpha motif domain containing 1 Hs.140309 [show with all ESTs]Unigene Representative Sequence: AY453840
GeneLoc Exon Structure
2 Ensembl transcripts including schematic representations: ENST00000269724
ENST00000397471
|
Expression
for SAMD1
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| SAMD1 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for SAMD1
1 / 2 / 3 3 probe-sets matching SAMD1 gene Data from
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: CCCCCCTTCT
SOURCE GeneReport for Unigene cluster: Hs.140309
UniProtKB/Swiss-Prot: SAMD1_HUMAN, Q6SPF0Tissue specificity: Expressed in atherosclerotic lesions, not in normal intima |
Orthologs
for SAMD1
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for SAMD1 gene from 3 species
About this table Species with no ortholog for SAMD1
ENSEMBL Gene Tree for SAMD1 | Paralogs
for SAMD1(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for SAMD1 gene
- SAMD132
|
SNPs/Variants
for SAMD1(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
The following additional 14 SNP(s) have been
found in Applied Biosystems data source:
(Click
for
Applied Biosystems TaqMan ® Genotyping Assay)
HapMap Linkage Disequilibrium images for SAMD1 (up to first 250kb)
|
Disorders & Mutations
for SAMD1
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
| -- |
Medical News
for SAMD1(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for SAMD1 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 8 PubMed articles for SAMD1 gene:- Atherin: a newly identified, lesion-specific, LDL-binding protein in human atherosclerosis. (PubMed id 16159594)1, 3, 4 Lees A.M.... Lees R.S. (2005)
- Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336)4 Cantin G.T....Yates J.R. III (2008)
- Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)4 Daub H.... Mann M. (2008)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)4 Dephoure N.... Gygi S.P. (2008)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)4 Olsen J.V....Mann M. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)4 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)3 Strausberg R.L....Marra M.A. (2002)
- Identifying polymer-forming SAM domains. (PubMed id 18831011)1 Meruelo A.D. and Bowie J.U. (2009)
|
Search for SAMD1
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SAMD1
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing SAMD1
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SAMD1(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| About This Section
| --
| Services
for SAMD1(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section
| 
Products for SAMD1:
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