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Aliases & Descriptions for SALL2
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| FLJ10414 2 | | FLJ55746 2 | | HSAL2 2, 5 | | HSal2 3 | | Hsal2 1 | | KIAA0360 1, 2, 3 | | SAL2 3 | | ZNF795 1, 2 | | p150(Sal2) 2 |
| | | Descriptions |
|---|
| Zinc finger protein SALL2 3 | | sal (Drosophila)-like 2 1 | | sal-like 2 2 | | sal-like 2 (Drosophila) 2 |
|
| | Search outside databases for aliases for SALL2 genePrevious GC identifers: GC14M019361 GC14M015776 GC14M019979 GC14M019980 GC14U900549 |
Summaries for SALL2(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: SALL2_HUMAN, Q9Y467Function: Probable transcription factorGene Wiki entry for SALL2 |
Genomic Location for SALL2
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Transcription factor binding sites upstream to the SALL2 gene 
Entrez Gene cytogenetic band: 14q11.1-q12 Ensembl cytogenetic band: 14q11.2 HGNC cytogenetic band: 14q11.1-q12.1SALL2 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14M021059:
(about GC identifiers)
Start:
|
21,059,071 bp from pter |
End:
|
21,075,177 bp from pter |
Size:
|
16,107 bases |
Orientation:
|
minus strand |
RefSeq DNA sequence:- NC_000014.7 NT_026437.11
| Proteins for SALL2
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: SALL2_HUMAN, Q9Y467 (See
protein sequence)Recommended Name: Sal-like protein 2 Size: 1007 amino acids; 105399 Da
Subcellular location: Nucleus (Probable)
Developmental stage: In fetal brain exclusively in pontine nuclei
Secondary accessions: B2RMX6 Q9Y4G1Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_005398.1
ENSEMBL proteins: ENSP00000333537 ENSP00000320536
Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
2 Gene Ontology (GO) cellular component terms (links to tree view): About this table
Antibodies for SALL2: Assays for SALL2: | Protein
Domains/ Families for SALL2(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q9Y467
ProtoNet protein and cluster: Q9Y467 UniProtKB/Swiss-Prot: SALL2_HUMAN, Q9Y467Similarity: Belongs to the sal C2H2-type zinc-finger protein familySimilarity: Contains 7 C2H2-type zinc fingers | Gene Function for SALL2
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|                OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): BC024245
Applied Biosystems Silencer® siRNAs for SALL2
Sigma-Aldrich siRNA for SALL2  Sigma-Aldrich shRNA for SALL2  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_005407                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_005407                                  untagged cDNA clones in CMV expression vector (see all 2): NM_005407 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_005407
UniProtKB/Swiss-Prot: SALL2_HUMAN, Q9Y467Function: Probable transcription factorGenatlas biochemistry entry for SALL2:brain specific transcription factor,Drosophila homeotic gene Sal-like 2,expressed in different brain areas4 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Sall2):
3 Gene Ontology (GO) molecular function terms (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003700 | transcription factor activity |
NAS | -- | | GO:0008270 | zinc ion binding |
IEA | -- | | GO:0046872 | metal ion binding |
IEA | -- | About this table | Pathways & Interactions for SALL2
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
Gene Network CentralTM Interacting Genes and Proteins Network for SALL2 
1 Interacting protein for SALL2 (Q9Y4672) via UniProtKB, MINT, and/or STRINGAbout this table
2 Gene Ontology (GO) biological process terms (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006350 | transcription |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
NAS | -- | About this table
|
Drugs & Compounds for SALL2(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for SALL2
|
Transcripts for SALL2(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|                OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): BC024245
Sigma-Aldrich siRNA for SALL2  Sigma-Aldrich shRNA for SALL2  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_005407 REFSEQ mRNAs for SALL2 gene: NM_005407.1
Applied Biosystems TaqMan ® Gene Expression Assays: NM_005407               OriGene GFP tagged cDNA clone in CMV expression vector: NM_005407                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_005407                                  untagged cDNA clones in CMV expression vector (see all 2): NM_005407  Additional cDNA sequence: AB002358.2 AF465630.1 AK001276.1 AK294051.1 AK299931.1 BC136528.1 BC136529.1 CR614081.1 X98834.1 9 DOTS entries: DT.87013253 DT.92422658 DT.100755383 DT.100755384 DT.102823693 DT.100645217 DT.100664725 DT.100755386 DT.75102282
highest scoring ESTs for SALL2:AB002358 BI549867 CN399015 CN399023 CN399024 CN399027 CN399028 CN399032 X98834 AA211861 Unigene Clusters for SALL2: Sal-like 2 (Drosophila) Hs.416358 [show with all ESTs], Hs.719293 [show with all ESTs]Unigene Representative Sequences: AK296414, NM_005407
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for SALL2 (see all 6
)
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5 | ^ | 6a | · | 6b | |
| SP1: | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | |
| SP3: | |   | |   | - |   | - |   | |   | |   | - |   | - |   | - |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   |
About this scheme
ECgene alternative splicing isoforms for SALL2
2 Ensembl transcripts including schematic representations: ENST00000327430
ENST00000317492
|
Expression for SALL2
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| SALL2 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for SALL2
1 / 2 / 3 3 probe-sets matching SALL2 gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene clusters: Hs.416358 Hs.719293
Expression variation in blood from EXPOLDB for SALL2 UniProtKB/Swiss-Prot: SALL2_HUMAN, Q9Y467Tissue specificity: Highest levels in adult brain (in different areas). Lower levels in heart; very low levels in kidney and pancreas |
Orthologs for SALL2
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for SALL2 gene from 5 species
About this table Species with no ortholog for SALL2
ENSEMBL Gene Tree for SALL2 | Paralogs for SALL2(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| Paralogs for SALL2 gene
- ZNF2362
|
SNPs/Variants for SALL2(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for SALL2 (up to first 250kb)
|
Disorders & Mutations for SALL2
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 602219
|
Medical News for SALL2(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for SALL2 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 10/16 PubMed articles for SALL2 gene (see all 16
): |
Search for SALL2
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing SALL2
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing SALL2
(According to HUGE)
About This Section
| |
Specialized Databases showing SALL2(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for SALL2(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for SALL2:

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GeneCards Homepage - Last full update: 1 Jul 2009
Incremental update: 13 Oct 2009
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