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SALL1 Gene

protein-coding GIFtS: 60

GC16M049727

sal-like 1 (Drosophila)
(Previous name: sal (Drosophila)-like 1 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: TBS)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
HSAL1 ^², ⁵
HSal1 ^³
Hsal1 ^¹
SAL1 ^³
TBS ^², ⁵
ZNF794 ^¹, ²

Descriptions
Spalt-like transcription factor 1 ^², ³
Zinc finger protein SALL1 ^³
sal (Drosophila)-like 1 ^¹
sal-like 1 ^²
sal-like 1 (Drosophila) ^²

External Ids
HGNC: 10524¹
Entrez Gene: 6299²
UniProtKB: Q9NSC2³
Ensembl: ENSG00000103449⁷

Search outside databases for aliases for SALL1 gene

Previous GC identifers: GC16M041583 GC16M051217 GC16M050907 GC16M050948

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for SALL1:

The protein encoded by this gene is a zinc finger transcriptional repressor and may be part of the

NuRD histone deacetylase complex (HDAC). Defects in this gene are a cause of Townes-Brocks

syndrome (TBS) as well as bronchio-oto-renal syndrome (BOR). Two transcript variants encoding

different isoforms have been found for this gene. [provided by RefSeq]

UniProtKB/Swiss-Prot: SALL1_HUMAN, Q9NSC2

Function: Transcriptional repressor involved in organogenesis (By similarity)

Gene Wiki entry for SALL1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
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Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the SALL1 gene

Entrez Gene cytogenetic band: 16q12.1 Ensembl cytogenetic band: 16q12.1 HGNC cytogenetic band: 16q12.1

SALL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 16 GeneLoc Exon Structure

GeneLoc location for GC16M049727: (about GC identifiers)

Start:	49,727,387 bp from pter
End:	49,742,684 bp from pter
Size:	15,298 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000016.8 NT_010498.15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: SALL1_HUMAN, Q9NSC2 (See protein sequence)

Recommended Name: Sal-like protein 1

Size: 1324 amino acids; 140391 Da

Subunit: Interacts with HDAC1, HDAC2, RBBP4, RBPP7, MTA1 and MTA2 (By similarity). Interacts with

FAM58A. Probably associates with NuRD histone deacetylase complex (HDAC)

Subcellular location: Nucleus (By similarity)

Developmental stage: In fetal brain exclusively in neurons of the subependymal region of

hypothalamus lateral to the third ventricle

Secondary accessions: Q99881 Q9NSC3 Q9P1R0

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (2 alternative transcripts):

NP_001121364.1 NP_002959.2

ENSEMBL proteins:

ENSP00000251020

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (SALL1)
	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	IEA	--
GO:0005634	nucleus	IEA	--

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Antibodies for SALL1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse Antibodies at Sigma-Aldrich
	R&D Systems Antibodies for SALL1
	Antibodies from Abcam (SALL1), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (SALL1)
	Search Novus for antibodies for SALL1

Assays for SALL1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry Q9NSC2

ProtoNet protein and cluster: Q9NSC2

UniProtKB/Swiss-Prot: SALL1_HUMAN, Q9NSC2

Similarity: Belongs to the sal C2H2-type zinc-finger protein family

Similarity: Contains 9 C2H2-type zinc fingers

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (SALL1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (SALL1)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_002968

Applied Biosystems Silencer® siRNAs for SALL1

Sigma-Aldrich siRNA for SALL1

Sigma-Aldrich shRNA for SALL1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001127892
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001127892
untagged cDNA clones in CMV expression vector (see all 2): NM_001127892

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_002968

UniProtKB/Swiss-Prot: SALL1_HUMAN, Q9NSC2

Function: Transcriptional repressor involved in organogenesis (By similarity)

Genatlas biochemistry entry for SALL1:

brain specific transcription factor,Drosophila homeotic gene Sal-like 1,expressed in corpus

callosum and substantia nigra

12 MGI mutant phenotypes (inferred from 5 alleles) (MGI details for Sall1):

	behavior/neurological	digestive/alimentary	embryogenesis	growth/size
hearing/vestibular/ear	lethality-prenatal/perinatal	life span-post-weaning/aging	limbs/digits/tail	nervous system
renal/urinary system	skeleton

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003700	transcription factor activity	TAS	9425907
GO:0008270	zinc ion binding	IEA	--
GO:0046872	metal ion binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Gene Network Central^TM Interacting Genes and Proteins Network for SALL1

5/16 Interacting proteins for SALL1 (ENSP00000251020³) via UniProtKB, MINT, and/or STRING (see all 16 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SIX1	ENSP00000247182³	STRING (score=.94)
SHH	ENSP00000297261³	STRING (score=.875)
EPHA3	ENSP00000337451³	STRING (score=.865)
HOXA13	ENSP00000222753³	STRING (score=.865)
EPHA4	ENSP00000281821³	STRING (score=.845)

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5 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001657	ureteric bud development	IEA	--
GO:0006350	transcription	IEA	--
GO:0006355	regulation of transcription, DNA-dependent	IEA	--
GO:0009653	anatomical structure morphogenesis	TAS	9425907
GO:0031129	inductive cell-cell signaling	IEA	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for SALL1
1 Novoseek chemical compound relationship for SALL1 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
zinc	60.68	13	16088922 (2), 11102974 (1), 10965108 (1), 12925729 (1) (see all 12)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (SALL1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (SALL1)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_002968

Sigma-Aldrich siRNA for SALL1

Sigma-Aldrich shRNA for SALL1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001127892 NM_002968

REFSEQ mRNAs for SALL1 gene (2 alternative transcripts):

NM_001127892.1 NM_002968.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001127892 NM_002968

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001127892
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001127892
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_001127892

Additional cDNA sequence:

AK295103.1 AK307835.1 BC113881.1 BC113906.1 BC131548.1 Y18265.1

3 DOTS entries:

DT.408356 DT.95196922 DT.75196640

24/29 AceView cDNA sequences (see all 29 ):

AA932313 AU132405 AW166367 AA709028 BP350402 AU131453 AU123635 BP360753

NM_002968 AI376951 AI291817 AU130989 AA071082 AI002870 AI762905 BX505300

BM465643 Y18265 AI221270 AA856601 BF923314 AW768829 AU152837 AI291969

highest scoring ESTs for SALL1:

AA856601 BM465643 Y18265 AA071082 AA709028 AA932313 AI002870 AI174371 AI221270 AI245549

Unigene Cluster for SALL1:

Sal-like 1 (Drosophila)

Hs.135787 [show with all ESTs]

Unigene Representative Sequence: NM_001127892

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000251020

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

SALL1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for SALL1

¹ / ² / ³

6 probe-sets matching SALL1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
32985_at²^{, 3}	U95-A	1	1.00	1.00	0.97	0.87	AF017655	0.20	1.00	0.72	1
76244_at²^{, 3}	U95-E	1	1.00	1.00	0.98	1.16	AA856601	0.80	1.00	0.91	1
206893_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_002968	0.60	1.00	0.82	1
229273_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AU152837	0.60	1.00	0.82	1
206893_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
229273_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks SALL1 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: CACTTTCTTG

SOURCE GeneReport for Unigene cluster: Hs.135787
Expression variation in blood from EXPOLDB for SALL1
UniProtKB/Swiss-Prot: SALL1_HUMAN, Q9NSC2
Tissue specificity: Highest levels in kidney. Lower levels in adult brain (enriched in corpus
callosum, lower expression in substantia nigra) and liver

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for SALL1 gene from 5/11 species (see all 11 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	SALL1¹	--	sal-like 1 (Drosophila)	91.17(n) 94.1(a)	487284 XM_544410.2 XP_544410.2
chimpanzee (Pan troglodytes)	SALL1¹	--	sal-like 1 (Drosophila)	99.49(n) 99.15(a)	473281 XM_528651.2 XP_528651.2
cow (Bos taurus)	SALL1¹	--	sal-like 1 (Drosophila)	90.24(n) 93.38(a)	514467 XM_592327.3 XP_592327.2
rat (Rattus norvegicus)	Sall1¹	--	sal-like 1 (Drosophila)	88.04(n) 91.17(a)	307740 XM_226329.4 XP_226329.2
mouse (Mus musculus)	Sall1^{1, 5}	8⁵	sal-like 1 (Drosophila)^{1, 5}	87.69(n)¹ 90.83(a)¹	58198¹ NM_021390.2¹ NP_067365.1¹ AA386439⁵ AB051409⁵ (see all 12)

About this table Species with no ortholog for SALL1

ENSEMBL Gene Tree for SALL1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for SALL1 gene

SALL3² SALL4²

Pseudogenes

1 related pseudogene

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/87 NCBI SNPs in SALL1 are shown (see all 87 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 45)

AB	SNP ID	Valid	Chr 16 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs9938285^1,2	A,C,F,H	49744541(+)	`CGCCCC/TAATTC`	1	--	ng3¹		4		EU EA WA	414
--	rs4614723^1,2	C,F,H	49728676(+)	`ACTAAT/CAGGTG`	2	I/V	mis¹ ese³		5		WA EU EA	536
--	rs4785505^1,2	A,C	49743978(+)	`CTGAGA/CGCAGC`	1	--	ng3¹		0	--	--	--	--
--	rs1054478^1,2	C	49727522(-)	`CATGCA/CCTTTC`	2	--	ut3¹		1		MN	184
--	rs13336129^1,2	C	49733159(+)	`GCCGCC/TGCTGC`	2	S/G	mis¹ ese³		0	--	--	--	--
	rs3743767^1,2	F	49728332(+)	`GTTATA/GTCGCT`	2	--	ut3¹		1		EA	1492
	rs1965024^1,2	A,C,F,H,O	49731060(-)	`CCCCTC/TGAGAT`	2	L/L	syn¹ ese³		7		NA PA EU EA WA	670
	rs11645288^1,2	A,C,F,H	49730178(+)	`CTCTCA/GTGAAT`	2	H/H	syn¹ ese³		3		EU EA	300
--	rs3743768^1,2	F	49728788(+)	`GCTGCA/GTACTG`	2	Y/Y	syn¹ ese³		1		EA	1496
	rs1465338^1,2	A,C,F,H	49729171(-)	`AGAGAA/GTGAAC`	1	--	int¹		4		EU EA WA	412

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HapMap Linkage Disequilibrium images for SALL1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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OMIM: 602218 disorders: 107480 107480

UniProtKB/Swiss-Prot: SALL1_HUMAN, Q9NSC2

Defects in SALL1 are the cause of Townes-Brocks syndrome (TBS) [MIM:107840]. TBS is a

rare, autosomal dominant malformation syndrome with a combination of imperforate anus,

triphalangeal and supernumerary thumbs, malformed ears and sensorineural hearing loss

Defects in SALL1 may cause a phenotype overlapping with TBS, similar to bronchio-oto-renal

syndrome (BOR) [MIM:113650]. BOR is an autosomal dominant disorder, manifested by various

combinations of preauricular pits, branchial fistulae or cysts, lacrimal duct stenosis, hearing

loss, structural defects of the outer, middle, or inner ear, and renal dysplasia. Associated

defects include asthenic habitus, long narrow facies, constricted palate, deep overbite, and

myopia. Hearing loss may be due to Mondini type cochlear defect and stapes fixation

9 Novoseek disease relationships for SALL1 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
townes-brocks syndrome	99.26	43	16088922 (2), 16429401 (2), 17295837 (2), 19005989 (2) (see all 34)
okihiro syndrome	91.56	2	18818376 (1), 16790473 (1)
limb malformation	72.20	2	18000979 (2)
renal agenesis	62.87	1	16670092 (1)
renal dysplasia	56.91	1	10654325 (1)
developmental disabilities	49.89	2	18818376 (1), 18024993 (1)
heart defects congenital	41.35	2	15158448 (1), 17295837 (1)
congenital malformation	26.51	1	16670092 (1)
renal failure chronic	13.06	1	16971658 (1)

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GeneTests: SALL1

Townes-Brocks Syndrome

Human Gene Mutation Database: SALL1

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/63 PubMed articles for SALL1 gene (see all 63 ):

Mutations in the SALL1 putative transcription factor gene cause Townes-Brocks syndrome. (PubMed id 9425907)^{1, 2, 3, 4} Kohlhase J.... Engel W. (1998)
Molecular analysis of SALL1 mutations in Townes-Brocks syndrome. (PubMed id 9973281)^{1, 3, 4} Kohlhase J.... Engel W. (1999)
Townes-Brocks syndrome: detection of a SALL1 mutation hot spot and evidence for a position effect in one patient. (PubMed id 10533063)^{1, 3, 4} Marlin S.... Petit C. (1999)
A SALL1 mutation causes a branchio-oto-renal syndrome-like phenotype. (PubMed id 10928856)^{1, 3, 4} Engels S.... McGaughran J. (2000)
Isolation, characterization, and organ-specific expression of two novel human zinc finger genes related to the Drosophila gene spalt. (PubMed id 8975705)^{3, 4} Kohlhase J.... Stick R. (1996)
Detection of heterozygous SALL1 deletions by quantitative real time PCR proves the contribution of a SALL1 dosage effect in the pathogenesis of Townes-Brocks syndrome. (PubMed id 16429401)^{1, 3} Borozdin W....Kohlhase J. (2006)
Transcriptional activation of the SALL1 by the human SIX1 homeodomain during kidney development. (PubMed id 16670092)^{1, 3} Chai L....Ma Y. (2006)
SALL1 mutation analysis in Townes-Brocks syndrome: twelve novel mutations and expansion of the phenotype. (PubMed id 16088922)^{1, 3} Botzenhart E.M....Kohlhase J. (2005)
Molecular cloning, chromosomal localization, and expression of the murine SALL1 ortholog Sall1. (PubMed id 10965108)^{1, 3} Buck A....Kohlhase J. (2000)
The association of an epibulbar dermoid and Duane syndrome in a patient with a SALL1 mutation (Townes-Brocks Syndrome). (PubMed id 19005989)^{1, 3} Barry J.S. and Reddy M.A. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Disorders
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 6299	HGNC: 10524	AceView: SALL1	Ensembl:ENSG00000103449	euGenes: HUgn6299
ECgene: SALL1	H-InvDB: SALL1

(According to HUGE)
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(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
GeneReviews	http://www.genetests.org/query?gene=SALL1

Licensable Technologies for SALL1
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for SALL1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for SALL1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for SALL1		Browse antibodies at Sigma-Aldrich
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
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SALL1 Gene

protein-coding GIFtS: 60

Aliases &
Descriptions
for SALL1

Summaries
for SALL1

Genomic Location
for SALL1

Proteins
for SALL1

Protein Domains/
Families
for SALL1

Gene Function
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Pathways & Interactions
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Transcripts
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Expression
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Orthologs
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for SALL1

Search for SALL1

Genome Databases showing SALL1

Other Databases showing SALL1

Specialized Databases showing SALL1

Licensable Technologies
for SALL1

Services
for SALL1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

SALL1 Gene

protein-coding GIFtS: 60

Aliases & Descriptionsfor SALL1

Summariesfor SALL1

Genomic Locationfor SALL1

Proteinsfor SALL1

Protein Domains/Familiesfor SALL1

Gene Functionfor SALL1

Pathways & Interactionsfor SALL1

Drugs & Compoundsfor SALL1

Transcriptsfor SALL1

Expression for SALL1

Orthologsfor SALL1

Paralogsfor SALL1

SNPs/Variantsfor SALL1

Disorders & Mutationsfor SALL1

Medical Newsfor SALL1

Publicationsfor SALL1

Search for SALL1

Genome Databases showing SALL1

Other Databases showing SALL1

Specialized Databases showing SALL1

Licensable Technologiesfor SALL1

Servicesfor SALL1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for SALL1

Summaries
for SALL1

Genomic Location
for SALL1

Proteins
for SALL1

Protein Domains/
Families
for SALL1

Gene Function
for SALL1

Pathways & Interactions
for SALL1

Drugs & Compounds
for SALL1

Transcripts
for SALL1

Expression
for SALL1

Orthologs
for SALL1

Paralogs
for SALL1

SNPs/Variants
for SALL1

Disorders & Mutations
for SALL1

Medical News
for SALL1

Publications
for SALL1

Licensable Technologies
for SALL1

Services
for SALL1