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SAFB2 Gene

protein-coding   GIFtS: 53
GCID: GC19M005587

Scaffold Attachment Factor B2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Scaffold Attachment Factor B21 2
SAF-B22 3
KIAA01383 5

External Ids:    HGNC: 216051   Entrez Gene: 96672   Ensembl: ENSG000001302547   OMIM: 6080665   UniProtKB: Q141513   

Export aliases for SAFB2 gene to outside databases

Previous GC identifers: GC19M005527 GC19M005538 GC19M005348


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SAFB2 Gene:
SAFB2 (scaffold attachment factor B2) is a protein-coding gene. Diseases associated with SAFB2 include familial breast cancer, and breast cancer. GO annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is SLTM.

UniProtKB/Swiss-Prot: SAFB2_HUMAN, Q14151
Function: Binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor
and can also inhibit cell proliferation

Gene Wiki entry for SAFB2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000019.10  NT_011295.12  NC_018930.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SAFB2 gene promoter:
         Pax-5   Sp1   HSF2   Pax-2   ZID   Pax-2a   CUTL1   Zic3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSAFB2 promoter sequence
   Search Chromatin IP Primers for SAFB2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SAFB2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.3   Ensembl cytogenetic band:  19p13.3   HGNC cytogenetic band: 19p13.3

SAFB2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SAFB2 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M005587:  view genomic region     (about GC identifiers)

Start:
5,587,010 bp from pter      End:
5,624,057 bp from pter
Size:
37,048 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: SAFB2_HUMAN, Q14151 (See protein sequence)
Recommended Name: Scaffold attachment factor B2  
Size: 953 amino acids; 107473 Da
Subunit: Interacts with SAFB/SAFB1 and SCAM1. Interacts with isoform 2 SRPK1 and inhibits its activity
Sequence caution: Sequence=BAA09487.2; Type=Erroneous initiation;
Secondary accessions: Q8TB13

Explore the universe of human proteins at neXtProt for SAFB2: NX_Q14151

Explore proteomics data for SAFB2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys293, Lys424, Lys429, Lys616
  • Modification sites at PhosphoSitePlus

  • See SAFB2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055464.1  
    ENSEMBL proteins: 
     ENSP00000252542   ENSP00000467981   ENSP00000468505   ENSP00000468454  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RBM: RNA binding motif (RRM) containing

    3 InterPro protein domains:
     IPR012677 Nucleotide-bd_a/b_plait
     IPR003034 SAP_dom
     IPR000504 RRM_dom

    Graphical View of Domain Structure for InterPro Entry Q14151

    ProtoNet protein and cluster: Q14151

    2 Blocks protein domains:
    IPB000504 RNA-binding region RNP-1 (RNA recognition motif)
    IPB003034 DNA-binding SAP


    UniProtKB/Swiss-Prot: SAFB2_HUMAN, Q14151
    Similarity: Contains 1 RRM (RNA recognition motif) domain
    Similarity: Contains 1 SAP domain


    SAFB2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SAFB2_HUMAN, Q14151
    Function: Binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor
    and can also inhibit cell proliferation

         Gene Ontology (GO): Selected molecular function terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0003723RNA binding ----
    GO:0005515protein binding IPI12660241
         
    SAFB2 for ontologies           About GeneDecksing


    Animal Models:
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    Selected qRT-PCR Assays for microRNAs that regulate SAFB2 (see all 10):
    hsa-miR-206 hsa-miR-3673 hsa-miR-3688-3p hsa-miR-130a* hsa-miR-1 hsa-miR-23c hsa-miR-23b hsa-miR-23a
    SwitchGear 3'UTR luciferase reporter plasmidSAFB2 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SAFB2_HUMAN, Q14151: Cytoplasm. Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IEA--
    GO:0043231intracellular membrane-bounded organelle IDA--

    SAFB2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SAFB2
    Interactions:

        Search GeneGlobe Interaction Network for SAFB2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for SAFB2 (Q141511, 2, 3 ENSP000002525424) via UniProtKB, MINT, STRING, and/or I2D (see all 38)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SAFBQ154241, 3, ENSP000002921234EBI-352869,EBI-348298 I2D: score=4 STRING: ENSP00000292123
    SAFB2Q141511, 2EBI-352869,EBI-352869 MINT-7228483 MINT-7228306
    CHGBP050602, 3MINT-64171 I2D: score=5 
    MAP1LC3BQ9GZQ81, 3EBI-352869,EBI-373144 I2D: score=2 
    GABARAPL1Q9H0R81, 3EBI-352869,EBI-746969 I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--

    SAFB2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SAFB2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SAFB2 gene: 
    NM_014649.2  

    Unigene Cluster for SAFB2:

    Scaffold attachment factor B2
    Hs.655392  [show with all ESTs]
    Unigene Representative Sequence: NM_014649
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000252542(uc002mcd.3 uc010xio.1 uc010xip.1) ENST00000587802
    ENST00000589925 ENST00000590000 ENST00000585449 ENST00000591123 ENST00000592599
    ENST00000591101 ENST00000591310 ENST00000591120 ENST00000590262
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate SAFB2 (see all 10):
    hsa-miR-206 hsa-miR-3673 hsa-miR-3688-3p hsa-miR-130a* hsa-miR-1 hsa-miR-23c hsa-miR-23b hsa-miR-23a
    SwitchGear 3'UTR luciferase reporter plasmidSAFB2 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector: SAFB2 (NM_014649)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SAFB2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SAFB2
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    OriGene qSTAR qPCR primer pairs in human, mouse for SAFB2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SAFB2
      QuantiTect SYBR Green Assays in human, mouse, rat SAFB2
      QuantiFast Probe-based Assays in human, mouse, rat SAFB2

    Additional mRNA sequence: 

    AK123246.1 AK296552.1 AK300501.1 BC001216.1 BC014784.1 BC025279.1 D50928.1 

    Selected DOTS entries (see all 26):

    DT.95284311  DT.75176560  DT.99958547  DT.99977968  DT.40110022  DT.100814583  DT.97860337  DT.121455574 
    DT.75103418  DT.91742864  DT.121455580  DT.40306882  DT.450237  DT.91863535  DT.95363107  DT.100040325 
    DT.100811853  DT.65287715  DT.75119206  DT.92030453  DT.97819785  DT.97820339  DT.100705744  DT.100737017 

    Selected AceView cDNA sequences (see all 194):

    BE395325 BM746190 BU181609 BX283817 BU161744 BQ271895 BM929597 BQ883292 
    BE408763 CA395703 AK123246 BM708690 BQ058036 BM772135 BC014784 BU527192 
    AW136754 AI168419 BM552232 BM683580 BM174910 BU195637 BE395118 BM741943 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for SAFB2 (see all 8)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14a · 14b ^ 15 ^ 16 ^ 17 ^ 18a · 18b · 18c ^ 19 ^ 20a ·
    SP1:                                                                                                                                                            
    SP2:        -     -                                                                                                                                             
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 20b ^ 21
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for SAFB2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SAFB2 expression in normal human tissues (normalized intensities)      SAFB2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGTAGCTCA
    SAFB2 Expression
    About this image


    SAFB2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Eye (Sensory Organs)
             Retina
     
     Ovary (Reproductive System)
    SAFB2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SAFB2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.655392

    UniProtKB/Swiss-Prot: SAFB2_HUMAN, Q14151
    Tissue specificity: Expressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number
    of breast cancer cell lines

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SAFB2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SAFB2 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Safb21 , 5 scaffold attachment factor B21, 5 77.17(n)1
    74.23(a)1
      17 (29.39 cM)5
    2249021  NM_001029979.21  NP_001025150.21 
     565609655 
    chicken
    (Gallus gallus)
    Aves --
    --
    Uncharacterized protein
    63(a)
    59(a)
    many ↔ many
    many ↔ many
    28(1289385-1302977)
    28(1274595-1288936)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    51(a)
    many ↔ many
    GL343717.1(6762-34210)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.54902 Xenopus laevis transcribed sequence with moderate similarity more 76.44(n)    BJ626792.1 
    zebrafish
    (Danio rerio)
    Actinopterygii safb6
    scaffold attachment factor B
    47(a)
    1 → many
    22(15841906-15850925) ENSDARG00000020467
    fruit fly
    (Drosophila melanogaster)
    Insecta Saf-B6
    Scaffold attachment factor B
    23(a)
    1 → many
    3R(20643186-20648072)


    ENSEMBL Gene Tree for SAFB2 (if available)
    TreeFam Gene Tree for SAFB2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SAFB2 gene
    SLTM2  SAFB2  
    2 SIMAP similar genes for SAFB2 using alignment to 5 protein entries:     SAFB2_HUMAN (see all proteins):
    SAFB    SLTM

    SAFB2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SAFB2 (see all 865)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1939209061,2
    Cuntested15604877(-) CATGTC/TGACAT 2 S L mis10--------
    rs1888907671,2
    --5586575(+) AGCCAC/GGGGAG 1 -- int10--------
    rs1127462771,2
    C,F--5586682(+) CAGGGC/TCTGGC 1 -- int12Minor allele frequency- T:0.04NA 122
    rs1397726221,2
    --5586707(+) ACCCAC/TGCAGA 1 -- int10--------
    rs104129191,2
    C,F,A--5586749(+) GGCCCT/CATGGT 1 -- int19Minor allele frequency- C:0.12NA WA CSA EA 369
    rs1171970991,2
    C,F--5586772(+) CTGAAG/CAATTC 1 -- int11Minor allele frequency- C:0.02NA 120
    rs7334491,2
    C,F,H--5586820(+) TCCCAT/CGATGG 1 -- int119Minor allele frequency- C:0.12NA EA NS WA CSA 1021
    rs563212831,2
    C--5586879(+) TGATGC/TAGGCA 1 -- int14Minor allele frequency- T:0.12CSA WA NA EA 360
    rs729770751,2
    --5586915(+) GCCAAC/TAGTCA 1 -- int10--------
    rs1436335921,2
    --5586940(+) CACTGA/CGCCCA 1 -- int10--------

    HapMap Linkage Disequilibrium report for SAFB2 (5587010 - 5624057 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for SAFB2:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv2395CNV Insertion18451855
    dgv3693n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SAFB2
    DNA2.0 Custom Variant and Variant Library Synthesis for SAFB2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608066    OMIM disorders: --

    2 diseases for SAFB2:    About MalaCards
    familial breast cancer    breast cancer


    SAFB2 for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: SAFB2 (1 document)

    Export disorders for SAFB2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SAFB2 gene, integrated from 10 sources (see all 49):
    (articles sorted by number of sources associating them with SAFB2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. SAFB2, a new scaffold attachment factor homolog and estrogen receptor corepressor. (PubMed id 12660241)1, 2, 3, 9 Townson S.M.... Oesterreich S. (J. Biol. Chem. 2003)
    2. The enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2. (PubMed id 19674106)1, 2 Tsianou D....Georgatsou E. (FEBS J. 2009)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (Nature 2004)
    6. Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 8590280)1, 2 Nagase T.... Nomura N. (DNA Res. 1995)
    7. No germline mutations in supposed tumour suppressor genes SAFB1 and SAFB2 in familial breast cancer with linkage to 19p. (PubMed id 19077293)1, 9 Bergman A....Nordling M. (BMC Med. Genet. 2008)
    8. Scaffold attachment factors SAFB1 and SAFB2: Innocent bystanders or critical players in breast tumorigenesis? (PubMed id 14587024)1, 9 Oesterreich S. (J. Cell. Biochem. 2003)
    9. Low SAFB levels are associated with worse outcome in breast cancer patients. (PubMed id 19137425)1, 9 Hammerich-Hille S....Oesterreich S. (Breast Cancer Res. Treat. 2010)
    10. SAFB1 mediates repression of immune regulators and apoptotic genes in breast cancer cells. (PubMed id 19901029)1, 9 Hammerich-Hille S....Oesterreich S. (J. Biol. Chem. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9667 HGNC: 21605 AceView: SAFB2 Ensembl:ENSG00000130254 euGenes: HUgn9667
    ECgene: SAFB2 H-InvDB: SAFB2

    (According to HUGE)
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    HUGE: KIAA0138

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SAFB2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SAFB2 gene:
    Search GeneIP for patents involving SAFB2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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