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Aliases for SAAL1 Gene

Aliases for SAAL1 Gene

  • Serum Amyloid A-Like 1 2 3
  • Synoviocyte Proliferation-Associated In Collagen-Induced Arthritis 1 3
  • Protein SAAL1 3
  • SPACIA1 3

External Ids for SAAL1 Gene

Previous GeneCards Identifiers for SAAL1 Gene

  • GC11M018059
  • GC11M017784

Summaries for SAAL1 Gene

GeneCards Summary for SAAL1 Gene

SAAL1 (Serum Amyloid A-Like 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SAAL1 Gene

Genomics for SAAL1 Gene

Regulatory Elements for SAAL1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SAAL1 Gene

Start:
18,069,935 bp from pter
End:
18,106,091 bp from pter
Size:
36,157 bases
Orientation:
Minus strand

Genomic View for SAAL1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SAAL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SAAL1 Gene

Proteins for SAAL1 Gene

  • Protein details for SAAL1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96ER3-SAAL1_HUMAN
    Recommended name:
    Protein SAAL1
    Protein Accession:
    Q96ER3
    Secondary Accessions:
    • A6NH05

    Protein attributes for SAAL1 Gene

    Size:
    474 amino acids
    Molecular mass:
    53558 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SAAL1 Gene

Proteomics data for SAAL1 Gene at MOPED

Post-translational modifications for SAAL1 Gene

  • Ubiquitination at Lys209 and Lys254
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for SAAL1 Gene

Domains for SAAL1 Gene

Protein Domains for SAAL1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for SAAL1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96ER3

UniProtKB/Swiss-Prot:

SAAL1_HUMAN :
  • Q96ER3
Family:
  • Belongs to the SAAL1 family.
genes like me logo Genes that share domains with SAAL1: view

No data available for Gene Families for SAAL1 Gene

Function for SAAL1 Gene

Gene Ontology (GO) - Molecular Function for SAAL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005488 binding --
genes like me logo Genes that share ontologies with SAAL1: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SAAL1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SAAL1 Gene

Localization for SAAL1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SAAL1 Gene COMPARTMENTS Subcellular localization image for SAAL1 gene
Compartment Confidence
cytosol 2
extracellular 2
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for SAAL1 Gene

Pathways for SAAL1 Gene

SuperPathways for SAAL1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SAAL1 Gene

None

No data available for Pathways by source for SAAL1 Gene

Transcripts for SAAL1 Gene

mRNA/cDNA for SAAL1 Gene

Unigene Clusters for SAAL1 Gene

Serum amyloid A-like 1:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SAAL1

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for SAAL1
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SAAL1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12 ^ 13
SP1: - - - -
SP2: - - - -
SP3: - - - -
SP4:
SP5:
SP6:

Relevant External Links for SAAL1 Gene

GeneLoc Exon Structure for
SAAL1
ECgene alternative splicing isoforms for
SAAL1

Expression for SAAL1 Gene

mRNA expression in normal human tissues for SAAL1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for SAAL1 Gene

SOURCE GeneReport for Unigene cluster for SAAL1 Gene Hs.591998

genes like me logo Genes that share expressions with SAAL1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SAAL1 Gene

Orthologs for SAAL1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SAAL1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SAAL1 35
  • 99.58 (n)
  • 99.37 (a)
SAAL1 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SAAL1 35
  • 90.49 (n)
  • 90.91 (a)
SAAL1 36
  • 64 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SAAL1 35
  • 91.49 (n)
  • 90.26 (a)
SAAL1 36
  • 90 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Saal1 35
  • 82.28 (n)
  • 79.75 (a)
Saal1 16
Saal1 36
  • 80 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SAAL1 36
  • 74 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SAAL1 36
  • 72 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC691143 35
  • 82.21 (n)
  • 79.96 (a)
chicken
(Gallus gallus)
Aves SAAL1 35
  • 72.73 (n)
  • 70.24 (a)
SAAL1 36
  • 69 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SAAL1 36
  • 63 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.7504 35
tropical clawed frog
(Silurana tropicalis)
Amphibia saal1 35
  • 59.71 (n)
  • 55.87 (a)
Str.3398 35
zebrafish
(Danio rerio)
Actinopterygii saal1 35
  • 57.25 (n)
  • 53.08 (a)
saal1 36
  • 48 (a)
OneToOne
zgc55505 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 23 (a)
OneToOne
Species with no ortholog for SAAL1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SAAL1 Gene

ENSEMBL:
Gene Tree for SAAL1 (if available)
TreeFam:
Gene Tree for SAAL1 (if available)

Paralogs for SAAL1 Gene

Selected SIMAP similar genes for SAAL1 Gene using alignment to 8 proteins:

genes like me logo Genes that share paralogs with SAAL1: view

No data available for Paralogs for SAAL1 Gene

Variants for SAAL1 Gene

Sequence variations from dbSNP and Humsavar for SAAL1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs871698 -- 18,105,762(-) CTTGC(A/G)TTTCG intron-variant
rs871699 -- 18,106,132(-) GTCCC(A/G)CCGGG upstream-variant-2KB
rs964833 -- 18,095,463(-) ATAGT(A/G)TATTT intron-variant
rs964834 -- 18,095,347(-) TTTGA(C/T)GATTA intron-variant
rs964835 -- 18,095,333(-) TATTT(G/T)TATAC intron-variant

Relevant External Links for SAAL1 Gene

HapMap Linkage Disequilibrium report
SAAL1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SAAL1 Gene

Disorders for SAAL1 Gene

No disorders were found for SAAL1 Gene.

No data available for UniProtKB/Swiss-Prot for SAAL1 Gene

Publications for SAAL1 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3
  3. Defining the human deubiquitinating enzyme interaction landscape. (PMID: 19615732) Sowa M.E. … Harper J.W. (Cell 2009) 3
  4. Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays. (PMID: 19953087) Persaud A. … Rotin D. (Mol. Syst. Biol. 2009) 3
  5. Systematic analysis of human protein complexes identifies chromosome segregation proteins. (PMID: 20360068) Hutchins J.R. … Peters J.M. (Science 2010) 3

Products for SAAL1 Gene

Sources for SAAL1 Gene

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