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serum amyloid A3 pseudogene
(Previous symbol: SAA3)
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Aliases
for SAA3P gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 8
| Aliases |
|---|
| Serum Amyloid A3 Pseudogene1 2 | | SAA31 2 |
| External Ids: | HGNC: 105151 | Entrez Gene: 62902 | Ensembl: ENSG000001667877 | | ORGUL members: | |
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| NONCODE:n372406 | |
Export aliases for SAA3P gene to outside databasesPrevious GC identifers: GC11M019254 GC11M019076 GC11M018174 GC11M018098 GC11M017816
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Summaries
for SAA3P gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for SAA3P gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_009237.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SAA3P gene promoter:
Max1 TBP FOXD3 POU2F1a POU2F1b FOXJ2 (long isoform) HOXA5 FOXJ2 POU2F1c c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for SAA3P
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SAA3P |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11p15.1 Ensembl cytogenetic band: 11p15.1 HGNC cytogenetic band: 11p15.1SAA3P Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M018090: view genomic region
(about GC identifiers)
Start:
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18,134,019 bp from pter |
End:
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18,137,679 bp from pter |
Size:
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3,661 bases |
Orientation:
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minus strand |
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Proteins
for SAA3P gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB: --
|
Protein
Domains /
Families
for SAA3P gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| -- |
Function
for SAA3P gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
Genatlas biochemistry entry for SAA3P:serum amyloid A3,pseudogene,constitutively expressed
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Pathways & Interactions
for SAA3P gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Unified GeneCards pathways About this table 
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Selenium Pathway | |
1  BioSystems Pathway for SAA3P
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SAA3P
|
Drugs & Compounds
for SAA3P gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SAA3P
Search CenterWatch for drugs/clinical trials and news about SAA3P
|
Transcripts
for SAA3P gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
Unigene Cluster for SAA3P: Serum amyloid A3 pseudogene Hs.454496 Unigene Representative Sequence: AY2091882 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000534768(uc001mnt.3) ENST00000533267
Additional cDNA sequence: AY209188.1 NR_026576.1 1 AceView cDNA sequence: AY209188
GeneLoc Exon Structure
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Expression
for SAA3P gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SAA3P expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CAGAGGATTC
About this image
Genevestigator expression for SAA3P
SOURCE GeneReport for Unigene cluster: Hs.454496
SABiosciences Custom PCR Arrays for SAA3P
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat SAA3P | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SAA3P | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SAA3P |
Orthologs
for SAA3P gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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--
ENSEMBL Gene Tree for SAA3P (if available)
TreeFam Gene Tree for SAA3P (if available) |
Paralogs
for SAA3P gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for SAA3P gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SAA3P (18134019 - 18137679 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SAA3P: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SAA3P |
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Disorders
/ Diseases
for SAA3P gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SAA3P for disorders About GeneDecksing
3  diseases for SAA3P: About MalaCardsrheumatoid arthritis hyperglycemia arthritis
1 Novoseek disease relationship for SAA3P gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| atherosclerosis |
13.3 |
1 |
15590982 (1) |
Export disorders for SAA3P gene to outside databases
|
Publications
for SAA3P gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SAA3P gene, integrated from 9 sources (see all 18):
(articles sorted by number of sources associating them with SAA3P) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Localization of four human serum amyloid A (SAA) protein superfamily genes to chromosome 11p: characterization of a fifth SAA-related gene sequence. (PubMed id 8325654)1, 3 Sellar G.C. and Whitehead A.S. (1993)
- The human serum amyloid A (SAA)-encoding gene GSAA1: nucleotide sequence and possible autocrine-collagenase-inducer function. (PubMed id 2558975)1, 3 Sack G.H. Jr. and Talbot C.C. Jr. (1989)
- Induction of human mammary-associated serum amyloid A3 expression by prolactin or lipopolysaccharide. (PubMed id 12589816)1, 9 Larson M.A....McDonald T.L. (2003)
- The human plasma proteome: a nonredundant list developed by combination of four separate sources. (PubMed id 14718574)1 Anderson N.L....Lobley A. (2004)
- Nonexpression of the human serum amyloid A three (SAA3) gene. (PubMed id 1755958)1 Kluve-Beckerman B.... Benson M.D. (1991)
- The fifth serum amyloid A-related gene sequence, GSAA4, is SAA3. (PubMed id 8047850)9 Watson G....Woo P. (1994)
- The acute phase reactant serum amyloid A (SAA3) is a novel substrate for degradation by the metalloproteinases collagenase and stromelysin. (PubMed id 8461313)9 Mitchell T.I....Brinckerhoff C.E. (1993)
- Serum amyloid A3 expression is stimulated by dexamethasone and interleukin-6 in 3T3-L1 adipocytes. (PubMed id 15590982)9 Fasshauer M....Paschke R. (2004)
- Purification and characterization of the serum amyloid A3 enhancer factor. (PubMed id 10455131)9 Bing Z.... Liao W.S.-L. (1999)
- Adipose tissue depots of Holstein cows are immune res ponsive: inflammatory gene expression in vitro. (PubMed id 19914024)9 Mukesh M....Loor J.J. (2010)
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External Searches for SAA3P gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing SAA3P gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SAA3P gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SAA3P gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SAA3P | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SAA3P gene:
Search GeneIP for patents involving SAA3P
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SAA3P gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SAA3P | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SAA3P | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SAA3P | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SAA3P | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SAA3P | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SAA3P |
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 |  |  |  | |
| | | | Search Tocris compounds for SAA3P |
| |  |  |  |  | | | | |
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 | | | SAA3P Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for SAA3P |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SAA3P |
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Last full update: 18 Mar 2013 -
Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013
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