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Aliases for SAA2-SAA4 Gene

Aliases for SAA2-SAA4 Gene

  • SAA2-SAA4 Readthrough 2 3 5

External Ids for SAA2-SAA4 Gene

Previous GeneCards Identifiers for SAA2-SAA4 Gene

  • GC11U901751
  • GC11M018254
  • GC11M018232

Summaries for SAA2-SAA4 Gene

Entrez Gene Summary for SAA2-SAA4 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring serum amyloid A2 and serum amyloid A4 genes on chromosome 11. The read-through transcript produces a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Dec 2010]

GeneCards Summary for SAA2-SAA4 Gene

SAA2-SAA4 (SAA2-SAA4 Readthrough) is a Protein Coding gene. An important paralog of this gene is SAA1.

Additional gene information for SAA2-SAA4 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SAA2-SAA4 Gene

Genomics for SAA2-SAA4 Gene

Regulatory Elements for SAA2-SAA4 Gene

Enhancers for SAA2-SAA4 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11H018253 0.4 ENCODE 0.7 -4.8 -4835 0.2 TEAD3 SAA2-SAA4 SAA2 GC11M018255
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SAA2-SAA4 on UCSC Golden Path with GeneCards custom track

Genomic Locations for SAA2-SAA4 Gene

Genomic Locations for SAA2-SAA4 Gene
17,320 bases
Minus strand

Genomic View for SAA2-SAA4 Gene

Genes around SAA2-SAA4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SAA2-SAA4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SAA2-SAA4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SAA2-SAA4 Gene

Proteins for SAA2-SAA4 Gene

  • Protein details for SAA2-SAA4 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    SAA2-SAA4 readthrough
    Protein Accession:

    Protein attributes for SAA2-SAA4 Gene

    208 amino acids
    Molecular mass:
    23353 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SAA2-SAA4 Gene

Post-translational modifications for SAA2-SAA4 Gene

No Post-translational modifications

Other Protein References for SAA2-SAA4 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SAA2-SAA4 Gene

Domains & Families for SAA2-SAA4 Gene

Gene Families for SAA2-SAA4 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for SAA2-SAA4 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SAA2-SAA4: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SAA2-SAA4 Gene

Function for SAA2-SAA4 Gene

Phenotypes From GWAS Catalog for SAA2-SAA4 Gene

Gene Ontology (GO) - Molecular Function for SAA2-SAA4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0042056 chemoattractant activity IBA --
genes like me logo Genes that share ontologies with SAA2-SAA4: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SAA2-SAA4 Gene

Localization for SAA2-SAA4 Gene

Gene Ontology (GO) - Cellular Components for SAA2-SAA4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IBA --
genes like me logo Genes that share ontologies with SAA2-SAA4: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for SAA2-SAA4 Gene

Pathways & Interactions for SAA2-SAA4 Gene

SuperPathways for SAA2-SAA4 Gene

No Data Available

Interacting Proteins for SAA2-SAA4 Gene

Gene Ontology (GO) - Biological Process for SAA2-SAA4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0050918 positive chemotaxis IEA --
GO:0060326 cell chemotaxis IBA --
genes like me logo Genes that share ontologies with SAA2-SAA4: view

No data available for Pathways by source and SIGNOR curated interactions for SAA2-SAA4 Gene

Drugs & Compounds for SAA2-SAA4 Gene

No Compound Related Data Available

Transcripts for SAA2-SAA4 Gene

mRNA/cDNA for SAA2-SAA4 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for SAA2-SAA4 Gene

No ASD Table

Relevant External Links for SAA2-SAA4 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SAA2-SAA4 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SAA2-SAA4 Gene

mRNA differential expression in normal tissues according to GTEx for SAA2-SAA4 Gene

This gene is overexpressed in Liver (x49.4).
genes like me logo Genes that share expression patterns with SAA2-SAA4: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SAA2-SAA4 Gene

Orthologs for SAA2-SAA4 Gene

This gene was present in the common ancestor of mammals.

Orthologs for SAA2-SAA4 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SAA4 33
  • 99.36 (n)
(Bos Taurus)
Mammalia SAA4 33
  • 75.97 (n)
(Rattus norvegicus)
Mammalia Saa4 33
  • 72.82 (n)
(Mus musculus)
Mammalia Saa4 33 16
  • 71.54 (n)
Species where no ortholog for SAA2-SAA4 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SAA2-SAA4 Gene

Gene Tree for SAA2-SAA4 (if available)
Gene Tree for SAA2-SAA4 (if available)

Paralogs for SAA2-SAA4 Gene

Paralogs for SAA2-SAA4 Gene

genes like me logo Genes that share paralogs with SAA2-SAA4: view

Variants for SAA2-SAA4 Gene

Sequence variations from dbSNP and Humsavar for SAA2-SAA4 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000157604 -- 18,246,593(+) ACTGG(A/T)GCAAT intron-variant
rs1000208051 -- 18,246,471(+) GTACT(A/G)ATACT intron-variant
rs1000319066 -- 18,233,676(+) CAGCT(-/A)AATTT intron-variant
rs1000390383 -- 18,240,393(+) TTCCA(A/G)CATCT intron-variant
rs1000414249 -- 18,236,392(+) CCCCA(C/T)TTCCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SAA2-SAA4 Gene

Variant ID Type Subtype PubMed ID
nsv982990 CNV duplication 23825009
nsv519650 CNV loss 19592680

Relevant External Links for SAA2-SAA4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SAA2-SAA4 Gene

Disorders for SAA2-SAA4 Gene

Relevant External Links for SAA2-SAA4

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SAA2-SAA4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SAA2-SAA4 Gene

Publications for SAA2-SAA4 Gene

  1. A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder. (PMID: 20889312) Wang KS … Aragam N (Schizophrenia research 2010) 3 60
  2. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T … Taylor TD (PloS one 2010) 3 60

Products for SAA2-SAA4 Gene

Sources for SAA2-SAA4 Gene

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