S1PR5 Gene
protein-coding GIFtS: 59
GCID: GC19M010626
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sphingosine-1-phosphate receptor 5(Previous names: endothelial differentiation, sphingolipid G-protein-coupled...)
(Previous symbol: EDG8)
| |
Aliases
for S1PR5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Sphingosine-1-Phosphate Receptor 51 2 | | S1P Receptor 52 3 | | EDG81 2 3 5 | | S1P Receptor Edg-82 3 | | Edg-81 2 | | SPPR-12 | | Endothelial Differentiation, Sphingolipid G-Protein-Coupled Receptor, 81 2 | | SPPR-22 | | Endothelial Differentiation G-Protein-Coupled Receptor 82 3 | | Sphingosine 1-Phosphate Receptor 52 | | Sphingosine 1-Phosphate Receptor Edg-82 3 | | Sphingosine 1-Phosphate Receptor EDG82 | | S1P52 3 | | |
Export aliases for S1PR5 gene to outside databasesPrevious GC identifers: GC19M010485 GC19M010201 |
Summaries
for S1PR5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for S1PR5:
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neuriteretraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1Pand the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of Gprotein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors;others (e.g., EDG2; MIM 602282) are LPA receptors.(supplied by OMIM, Mar 2008)
UniProtKB/Swiss-Prot: S1PR5_HUMAN, Q9H228Function: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid thatelicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12)subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glialcells into astrocytes and may affect proliferative activity of these cells
 summary
for S1PR5: Sphingosine-1-phosphate (S1P) receptors are a group of G-protein-coupled receptors that are currently
divided into five subtypes; S1P1, S1P2, S1P3, S1P4 and S1P5. They are expressed in a wide variety of
tissues, with each subtype exhibiting a different cell specificity, although they are found at their highest
density on leukocytes. S1P receptors couple to different G proteins to mediate a range of biological
effects; Gi/o modulates cellular survival, proliferation and motility; G12/13 modulates cytoskeletal
remodeling and cell-shape changes and Gq modulates a range of cellular effector functions.
Gene Wiki entry for S1PR5
|
Genomic Views
for S1PR5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011295.11
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the S1PR5 gene promoter:
USF1 MIF-1 GATA-2 Arnt Egr-4 Max USF-1 Pax-4a c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for S1PR5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat S1PR5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13.2 Ensembl cytogenetic band: 19p13.2 HGNC cytogenetic band: 19p13.2S1PR5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M010626: view genomic region
(about GC identifiers)
Start:
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10,623,418 bp from pter |
End:
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10,628,668 bp from pter |
Size:
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5,251 bases |
Orientation:
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minus strand |
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Proteins
for S1PR5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: S1PR5_HUMAN, Q9H228 (See
protein sequence)Recommended Name: Sphingosine 1-phosphate receptor 5 Size: 398 amino acids; 41775 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Developmental stage: At 24 weeks of gestation, fragments of radial glial fibers are positive within the cortical plateand subplate of allocortical areas. These positive fragments often appear enlarged as varicosities and some of themterminate at blood vessels. Between 28 and 30 weeks of gestation, all iso- and allocortical areas containimmunolabeled radial glial fibers revealing curvature next to sulci. After 32 weeks of gestation, radial glial fibersgradually disappear; instead positive transitional stages between radial glia and astrocytes were found
Secondary accessions: Q6NW11Alternative splicing: 2 isoforms: Q9H228-1 Q9H228-2 Explore the universe of human proteins at neXtProt for S1PR5: NX_Q9H228
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9H228
S1PR5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001159687.1 NP_110387.1
ENSEMBL proteins: ENSP00000328472 ENSP00000416915 ENSP00000464884 Reactome Protein details: Q9H228
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005886 | plasma membrane |
TAS | -- | | GO:0016021 | integral to membrane |
IEA | -- |
S1PR5 for ontologies About GeneDecksing
S1PR5 Antibody Products:
Assay Products for S1PR5: |
Protein
Domains /
Families
for S1PR5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
S1PR5 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9H228ProtoNet protein and cluster: Q9H228 2 Blocks protein families: IPB004061 Sphingosine 1-phosphate receptor family signature IPB005386 EDG-8 sphingosine 1-phosphate receptor signature
UniProtKB/Swiss-Prot: S1PR5_HUMAN, Q9H228Similarity: Belongs to the G-protein coupled receptor 1 family |
Function
for S1PR5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: S1PR5_HUMAN, Q9H228Function: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid thatelicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12)subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glialcells into astrocytes and may affect proliferative activity of these cells
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for S1PR5 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for S1PR5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat S1PR5 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for S1PR5 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004930 | G-protein coupled receptor activity |
-- | -- | | GO:0038036 | sphingosine-1-phosphate receptor activity |
IEA | -- |
S1PR5 for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for S1PR5:
Animal Models:
4 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for S1pr5):
S1PR5 for phenotypes About GeneDecksing
|
Pathways & Interactions
for S1PR5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Class A/1 (Rhodopsin-like receptors) | | | 2 | Signaling by GPCR | | | 3 | S1P4 pathway | | | 4 | Lysosphingolipid and LPA receptors | | | 5 | Signal Transduction of S1P Receptor | |
Pathway sources
See GeneCards unified pathways
Show all pathways
4  BioSystems Pathways for S1PR5
5/7 
Reactome Pathways for S1PR5 (see all 7)
1 
Kegg Pathway (Kegg details for S1PR5):
S1PR5 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for S1PR5
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/149 Interacting proteins for S1PR5 (Q9H2283 ENSP000003284724) via UniProtKB, MINT, STRING, and/or I2D (see all 149)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007186 | G-protein coupled receptor signaling pathway |
-- | -- | | GO:0045664 | regulation of neuron differentiation |
IEA | -- |
S1PR5 for ontologies About GeneDecksing
|
Drugs & Compounds
for S1PR5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
S1PR5 for compounds About GeneDecksing
Compounds for S1PR5 available from Tocris Bioscience About this table
1 HMDB Compound for S1PR5 About this table
1 Novoseek chemical compound relationship for S1PR5 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| sphingosine |
78.3 |
7 |
19211033 (2) |
Search CenterWatch for drugs/clinical trials and news about S1PR5
|
Transcripts
for S1PR5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for S1PR5 gene (2 alternative transcripts): NM_001166215.1 NM_030760.4 Unigene Cluster for S1PR5: Sphingosine-1-phosphate receptor 5 Hs.501561 [show with all ESTs]Unigene Representative Sequence: NM_0011662153 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000333430(uc002mot.2) ENST00000439028(uc002mou.2) ENST00000590601
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for S1PR5 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for S1PR5 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): S1PR5 (NM_030760) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for S1PR5 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat S1PR5 |
Additional cDNA sequence: AF088014.1 AF331840.1 AF331841.1 AF331842.1 AK074661.1 AK094880.1 BC034703.1 BC067781.1 7 DOTS entries: DT.101968559 DT.405571 DT.97839596 DT.100022816 DT.97839597 DT.121453900 DT.100728241 24/49 AceView cDNA sequences (see all 49): AF088014 AF331841 NM_030760 BX349015 BE646254 BF446252 CR619597 CB049904 AF331842 BX282038 AK074661 BI604025 BI839010 BC034703 AI420856 BC067781 BI752293 N47089 AI814092 N63601 AI635837 AI439969 AF331840 BI820384
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for S1PR5 About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | · | 3c |
|---|
|
| SP1: | | | - | | - | | - | | | | | | | | |
| SP2: | | | | | | | - | | | | | | | | |
| SP3: | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for S1PR5
|
Expression
for S1PR5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| S1PR5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGAGGTTGAA
About this image
See S1PR5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for S1PR5
SOURCE GeneReport for Unigene cluster: Hs.501561
UniProtKB/Swiss-Prot: S1PR5_HUMAN, Q9H228Tissue specificity: Widely expressed in the brain, most prominently in the corpus callosum, which is predominantlywhite matter. Detected in spleen, peripheral blood leukocytes, placenta, lung, aorta and fetal spleen. Low-levelsignal detected in many tissue extracts. Overexpressed in leukemic large granular lymphocytes. Isoform 1 ispredominantly expressed in peripheral tissues. Isoform 2 is expressed in brain, spleen and peripheral blood leukocytes
SABiosciences Expression via Pathway-Focused PCR Array including S1PR5:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for S1PR5
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat S1PR5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat S1PR5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat S1PR5 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for S1PR5 |
Orthologs
for S1PR5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for S1PR5 gene from 2/9 species (see all 9) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
S1PR56 |
-- |
53(a) |
1 ↔ 1 |
2(80239345-80240472) |
zebrafish
(Danio rerio) |
Actinopterygii |
s1pr5b6s1pr5a6 |
sphingosine-1-phosphate receptor 5a |
49(a)44(a) |
1 ↔ 1possible ortholog |
6(75011-79866) 3(19186846-19190333) |
ENSEMBL Gene Tree for S1PR5 (if available)
TreeFam Gene Tree for S1PR5 (if available) |
Paralogs
for S1PR5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for S1PR5 gene
- CNR12 GPR122 ENSG000002675342 LPAR22 CNR22 S1PR12 S1PR32 MC1R2
- LPAR12 MC3R2 MC5R2 MC2R2 GPR32 MC4R2 S1PR42 GPR62
- LPAR32
11 SIMAP similar genes for S1PR5 using alignment to 3 protein entries: S1PR5_HUMAN (see all proteins):EDG1 S1PR3 S1PR1 S1PR2 S1PR4 EDG2
LPAR1 LPAR3 LPAR2 GPR12 GPR3
S1PR5 for paralogs About GeneDecksing
|
Genomic Variants
for S1PR5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for S1PR5 (10623418 - 10628668 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for S1PR5: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing S1PR5 |
|
Disorders
/ Diseases
for S1PR5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
S1PR5 for disorders About GeneDecksing
OMIM gene information: 605146
OMIM disorders: --
7  diseases for S1PR5: About MalaCardscorpus callosum pertussis prostate cancer obesity
prostatitis leukemia neuronitis
Human Genome Epidemiology (HuGE) Navigator: S1PR5 (1 document)
Export disorders for S1PR5 gene to outside databases
|
Publications
for S1PR5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for S1PR5 gene, integrated from 9 sources (see all 29):
(articles sorted by number of sources associating them with S1PR5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization of the human and mouse sphingosine 1-phosphate receptor, S1P5 (Edg-8): structure-activity relationship of sphingosine1-phosphate receptors. (PubMed id 11705398)1, 2, 9 Im D.-S.... Lynch K.R. (2001)
- Evidence for the presence of the sphingosine-1-phosphate receptor Edg-8 in human radial glial fibers. (PubMed id 15530552)1, 2, 9 Ulfig N. and Briese M. (2004)
- Characterization of a human sphingosine-1-phosphate receptor gene (S1P5) and its differential expression in LGL leukemia. (PubMed id 12427546)1, 2, 9 Kothapalli R.... Loughran T.P. Jr. (2002)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
- Identification of G protein-coupled receptor genes from the human genome sequence. (PubMed id 12044878)1, 2 Takeda S.... Mitaku S. (2002)
- Comparative analysis of human and rat S1P(5) (edg8): differential expression profiles and sensitivities to antagonists. (PubMed id 12234605)1, 2 Niedernberg A.... Kostenis E. (2002)
- Characterization of a novel sphingosine 1-phosphate receptor, Edg-8. (PubMed id 10799507)1, 3 Im D.S....Lynch K.R. (2000)
- The sphingosine 1-phosphate receptor 5 and sphingosine kinases 1 and 2 are localised in centrosomes: possible role in regulating cell division. (PubMed id 19211033)1, 9 Gillies L....Pyne S. (2009)
|
External Searches for S1PR5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing S1PR5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing S1PR5 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing S1PR5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for S1PR5 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for S1PR5 gene:
Search GeneIP for patents involving S1PR5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for S1PR5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for S1PR5 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for S1PR5 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for S1PR5 | | | OriGene Protein Over-expression Lysate for S1PR5 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for S1PR5 | | OriGene 3'-UTR Clone for S1PR5 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for S1PR5 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for S1PR5 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for S1PR5 | | OriGene Custom Protein Services for S1PR5 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat S1PR5 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing S1PR5 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat S1PR5 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat S1PR5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat S1PR5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat S1PR5 |
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| | | | Tocris compounds for S1PR5 |
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 | | | S1PR5 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for S1PR5 |
|  |  |  | | | | ThermoFisher Antibodies for S1PR5 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat S1PR5 |
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