S1PR4 Gene
protein-coding GIFtS: 56
GCID: GC19P003178
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sphingosine-1-phosphate receptor 4(Previous names: endothelial differentiation, G-protein-coupled receptor...)
(Previous symbol: EDG6)
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Aliases
for S1PR4 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Sphingosine-1-Phosphate Receptor 41 2 | | S1P Receptor 42 3 | | EDG61 2 3 5 | | S1P Receptor Edg-62 3 | | S1P42 3 5 | | LPC12 | | Endothelial Differentiation, G-Protein-Coupled Receptor 61 2 | | SLP42 | | Endothelial Differentiation, Lysophosphatidic Acid G-Protein-Coupled Receptor,61 2 | | Endothelial Differentiation, G Protein Coupled Receptor 62 | | Endothelial Differentiation G-Protein Coupled Receptor 62 3 | | Sphingosine 1-Phosphate Receptor 42 | | Sphingosine 1-Phosphate Receptor Edg-62 3 | | |
Export aliases for S1PR4 gene to outside databasesPrevious GC identifers: GC19P003130 GC19P002945 |
Summaries
for S1PR4 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for S1PR4:
This gene is a member of the endothelial differentiation, G-protein-coupled (EDG)) receptor gene family. EDG receptorsbind lysophospholipids or lysosphingolipids as ligands, and are involved in cell signalling in many different celltypes. This EDG receptor gene is intronless and is specifically expressed in the lymphoid tissue. (provided by RefSeq,Jul 2008)
UniProtKB/Swiss-Prot: S1PR4_HUMAN, O95977Function: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid thatelicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processesthat are specific for lymphocytes
 summary
for S1PR4: Sphingosine-1-phosphate (S1P) receptors are a group of G-protein-coupled receptors that are currently
divided into five subtypes; S1P1, S1P2, S1P3, S1P4 and S1P5. They are expressed in a wide variety of
tissues, with each subtype exhibiting a different cell specificity, although they are found at their highest
density on leukocytes. S1P receptors couple to different G proteins to mediate a range of biological
effects; Gi/o modulates cellular survival, proliferation and motility; G12/13 modulates cytoskeletal
remodeling and cell-shape changes and Gq modulates a range of cellular effector functions.
Gene Wiki entry for S1PR4
|
Genomic Views
for S1PR4 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011255.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the S1PR4 gene promoter:
GR Pax-5 NRSF form 1 HSF1 (long) NRSF form 2 C/EBPalpha PPAR-alpha HEN1 HOXA5 HSF1short
Other transcription factors
Search SABiosciences Chromatin IP Primers for S1PR4
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat S1PR4 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13.3 Ensembl cytogenetic band: 19p13.3 HGNC cytogenetic band: 19p13.3S1PR4 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P003178: view genomic region
(about GC identifiers)
Start:
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3,172,344 bp from pter |
End:
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3,180,330 bp from pter |
Size:
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7,987 bases |
Orientation:
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plus strand |
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Proteins
for S1PR4 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: S1PR4_HUMAN, O95977 (See
protein sequence)Recommended Name: Sphingosine 1-phosphate receptor 4 Size: 384 amino acids; 41623 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
1 PDB 3D structure from  and Proteopedia  for S1PR4:2DCO (3D)
Secondary accessions: D6W612Explore the universe of human proteins at neXtProt for S1PR4: NX_O95977
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O95977
S1PR4 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_003766.1
ENSEMBL proteins: ENSP00000246115 Reactome Protein details: O95977
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
S1PR4 for ontologies About GeneDecksing
S1PR4 Antibody Products:
Assay Products for S1PR4: |
Protein
Domains /
Families
for S1PR4 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
S1PR4 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O95977ProtoNet protein and cluster: O95977 2 Blocks protein families: IPB004061 Sphingosine 1-phosphate receptor family signature IPB004064 EDG-6 sphingosine 1-phosphate receptor signature
UniProtKB/Swiss-Prot: S1PR4_HUMAN, O95977Similarity: Belongs to the G-protein coupled receptor 1 family |
Function
for S1PR4 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: S1PR4_HUMAN, O95977Function: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid thatelicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processesthat are specific for lymphocytes
Clone
Products: |  | EMD Millipore Clones for the Expression of S1PR4 | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for S1PR4 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for S1PR4 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: S1PR4 (NM_003775) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for S1PR4 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat S1PR4 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for S1PR4 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
S1PR4 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for S1PR4:
Animal Models:
Mouse knock-out S1pr4tm1Lipp for S1PR4
3 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for S1pr4):
S1PR4 for phenotypes About GeneDecksing
|
Pathways & Interactions
for S1PR4 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Class A/1 (Rhodopsin-like receptors) | | | 2 | Signaling by GPCR | | | 3 | Lysosphingolipid and LPA receptors | | | 4 | S1P4 pathway | | | 5 | Prostanoid ligand receptors | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3  BioSystems Pathways for S1PR4
5/7 
Reactome Pathways for S1PR4 (see all 7)
1 
Kegg Pathway (Kegg details for S1PR4):
S1PR4 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for S1PR4
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/154 Interacting proteins for S1PR4 (O959773 ENSP000002461154) via UniProtKB, MINT, STRING, and/or I2D (see all 154)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
S1PR4 for ontologies About GeneDecksing
|
Drugs & Compounds
for S1PR4 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
S1PR4 for compounds About GeneDecksing
Compounds for S1PR4 available from Tocris Bioscience About this table
1 HMDB Compound for S1PR4 About this table
1 Novoseek chemical compound relationship for S1PR4 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| lysophospholipid |
87.2 |
1 |
10753843 (1) |
Search CenterWatch for drugs/clinical trials and news about S1PR4
|
Transcripts
for S1PR4 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for S1PR4 gene: NM_003775.3 Unigene Cluster for S1PR4: Sphingosine-1-phosphate receptor 4 Hs.662006 [show with all ESTs]Unigene Representative Sequence: NM_0037752 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000591346 ENST00000246115(uc002lxg.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for S1PR4 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for S1PR4 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: S1PR4 (NM_003775) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for S1PR4 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat S1PR4 |
Additional cDNA sequence: AJ000479.1 BC014970.1 1 DOTS entry: DT.75163397 24/49 AceView cDNA sequences (see all 49): BI908610 BI906435 CR610253 AA353166 CR590635 AW451146 BI907726 BC014970 CA314158 CR608611 AL560216 BG744043 BF974516 BI762628 BG397972 BM922943 BX119598 CB529025 BI910894 BI906532 CD370174 AJ000479 AL560608 BI905951
GeneLoc Exon Structure
|
Expression
for S1PR4 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| S1PR4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCCTGGCAAC
About this image
See S1PR4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for S1PR4
SOURCE GeneReport for Unigene cluster: Hs.662006
UniProtKB/Swiss-Prot: S1PR4_HUMAN, O95977Tissue specificity: Specifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung.Considerable level of expression in adult and fetal spleen as well as adult peripheral leukocytes and lung. Lowerexpression in adult thymus, lymph node, bone marrow, and appendix as well as in fetal liver, thymus, and lung
SABiosciences Expression via Pathway-Focused PCR Array including S1PR4:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for S1PR4
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat S1PR4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat S1PR4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat S1PR4 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for S1PR4 |
Orthologs
for S1PR4 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for S1PR4 gene from 3/11 species (see all 11) About this table
ENSEMBL Gene Tree for S1PR4 (if available)
TreeFam Gene Tree for S1PR4 (if available) |
Paralogs
for S1PR4 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for S1PR4 gene
- CNR12 GPR122 ENSG000002675342 LPAR22 CNR22 S1PR12 S1PR32 MC1R2
- LPAR12 MC3R2 MC5R2 MC2R2 GPR32 MC4R2 GPR62 LPAR32
- S1PR52
9 SIMAP similar genes for S1PR4 using alignment to 1 protein entry: S1PR4_HUMAN:EDG1 S1PR1 S1PR2 S1PR3 LPAR3 S1PR5
LPAR2 LPAR1 EDG2
S1PR4 for paralogs About GeneDecksing
|
Genomic Variants
for S1PR4 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for S1PR4 (3172344 - 3180330 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for S1PR4: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing S1PR4 |
|
Disorders
/ Diseases
for S1PR4 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
S1PR4 for disorders About GeneDecksing
OMIM gene information: 603751
OMIM disorders: --
1  disease for S1PR4: About MalaCardspertussis
Export disorders for S1PR4 gene to outside databases
|
Publications
for S1PR4 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for S1PR4 gene, integrated from 9 sources (see all 31):
(articles sorted by number of sources associating them with S1PR4) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- EDG6, a novel G protein-coupled receptor related to receptors for bioactive lysophospholipids, is specifically expressed in lymphoid tissue. (PubMed id 9790765)1, 2, 3 Graeler M.H.... Lipp M. (1998)
- Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6. (PubMed id 10753843)1, 2, 9 Van Brocklyn J.R....Spiegel S. (2000)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Edg-6 as a putative sphingosine 1-phosphate receptor coupling to Ca(2+) signaling pathway. (PubMed id 10679247)1, 2 Yamazaki Y.... Ohta H. (2000)
- A single amino acid determines preference between phospholipids and reveals length restriction for activation of the S1P4 receptor. (PubMed id 15298705)1, 9 Holdsworth G....Parrill A.L. (2004)
- Sphingosine 1-phosphate induces chemotaxis of immature and modulates cytokine-release in mature human dendritic cells for emergence of Th2 immune responses. (PubMed id 11919175)1, 9 Idzko M....Norgauer J. (2002)
- Discovery, design and synthesis of novel potent and se lective sphingosine-1-phosphate 4 receptor (S1P_4-R) agonists. (PubMed id 22119461)1 Guerrero M....Roberts E. (2012)
- Expression of sphingosine 1-phosphate receptor 4 and s phingosine kinase 1 is associated with outcome in oestrogen receptor-negative br east cancer. (PubMed id 22460268)1 Ohotski J....Edwards J. (2012)
- Sphingosine 1-phosphate receptor 4 uses HER2 (ERBB2) to regulate extracellular signal regulated kinase-1/2 in MDA-MB-453 breast canc er cells. (PubMed id 20837468)1 Long J.S....Pyne N.J. (2010)
- Shaping of terminal megakaryocyte differentiation and proplatelet development by sphingosine-1-phosphate receptor S1P4. (PubMed id 20686109)1 Golfier S....Lipp M. (2010)
|
External Searches for S1PR4 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing S1PR4 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing S1PR4 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing S1PR4 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for S1PR4 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for S1PR4 gene:
Search GeneIP for patents involving S1PR4
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for S1PR4 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for S1PR4 | | OriGene shRNA RFP for S1PR4 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for S1PR4 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for S1PR4 | | | OriGene Protein Over-expression Lysate for S1PR4 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for S1PR4 | | OriGene 3'-UTR Clone for S1PR4 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for S1PR4 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for S1PR4 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for S1PR4 | | OriGene Custom Protein Services for S1PR4 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat S1PR4 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing S1PR4 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat S1PR4 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat S1PR4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat S1PR4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat S1PR4 |
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 |  |  |  | |
| | | | Tocris compounds for S1PR4 |
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 | | | S1PR4 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for S1PR4 |
|  |  |  | | | | ThermoFisher Antibodies for S1PR4 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat S1PR4 |
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