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S100P Gene

protein-coding   GIFtS: 63
GCID: GC04P006700

S100 Calcium Binding Protein P

(Previous name: S100 calcium-binding protein P)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
S100 Calcium Binding Protein P1 2     MIG92 3
S100 Calcium-Binding Protein P1 2 3     Protein S100-P2
Migration-Inducing Gene 9 Protein2 3     S100E3
Protein S100-E2 3     

External Ids:    HGNC: 105041   Entrez Gene: 62862   Ensembl: ENSG000001639937   OMIM: 6006145   UniProtKB: P258153   
ORGUL members:         

Export aliases for S100P gene to outside databases

Previous GC identifers: GC04M006590 GC04P006816 GC04P006687 GC04P006759 GC04P006812 GC04P006695 GC04P006628 GC04P006696 GC04P006698


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for S100P Gene:
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding
motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the
regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes
include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at
4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the
etiology of prostate cancer. (provided by RefSeq, Jul 2008)

GeneCards Summary for S100P Gene:
S100P (S100 calcium binding protein P) is a protein-coding gene. Diseases associated with S100P include parachordoma, and pancreatic ductal adenocarcinoma. GO annotations related to this gene include calcium-dependent protein binding and calcium ion binding. An important paralog of this gene is S100A11.

UniProtKB/Swiss-Prot: S100P_HUMAN, P25815
Function: May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent
manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in
physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in
an autocrine manner via activation of the receptor for activated glycation end products (RAGE)

Gene Wiki entry for S100P Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000004.12  NC_018915.2  NT_006051.19  
Regulatory elements:
   Regulatory transcription factor binding sites in the S100P gene promoter:
         AREB6   NF-kappaB   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): S100P promoter sequence
   Search Chromatin IP Primers for S100P

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat S100P


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4p16   Ensembl cytogenetic band:  4p16.1   HGNC cytogenetic band: 4p16

S100P Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
S100P gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P006700:  view genomic region     (about GC identifiers)

Start:
6,694,796 bp from pter      End:
6,698,897 bp from pter
Size:
4,102 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: S100P_HUMAN, P25815 (See protein sequence)
Recommended Name: Protein S100-P  
Size: 95 amino acids; 10400 Da
Subunit: Homodimer and heterodimer with S100A1. Interacts with S100PBP and S100Z. Interacts with CACYBP in a
calcium-dependent manner. Dimeric form binds to and activates EZR/Ezrin by unmasking its F-actin binding sites.
Interacts with PPP5C (via TPR repeats); the interaction is calcium-dependent and modulates PPP5C activity
Miscellaneous: This protein binds two calcium ions
Sequence caution: Sequence=AAS00487.1; Type=Miscellaneous discrepancy; Note=Sequencing error in Met-1 codon;
2 PDB 3D structures from and Proteopedia for S100P:
1J55 (3D)        1OZO (3D)    
Secondary accessions: Q5J7W2

Explore the universe of human proteins at neXtProt for S100P: NX_P25815

Explore proteomics data for S100P at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See S100P Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_005971.1  
    ENSEMBL proteins: 
     ENSP00000296370  

    S100P Human Recombinant Protein Products:

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    S100P Assay Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    EFHAND: EF-hand domain containing
    S100: S100 calcium binding proteins

    5 InterPro protein domains:
     IPR011992 EF-hand-dom_pair
     IPR002048 EF_hand_dom
     IPR013787 S100_Ca-bd_sub
     IPR028494 S100P
     IPR001751 S100/CaBP-9k_CS

    Graphical View of Domain Structure for InterPro Entry P25815

    ProtoNet protein and cluster: P25815

    1 Blocks protein domain: IPB001751 Calcium-binding protein

    UniProtKB/Swiss-Prot: S100P_HUMAN, P25815
    Similarity: Belongs to the S-100 family
    Similarity: Contains 2 EF-hand domains


    S100P for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: S100P_HUMAN, P25815
    Function: May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent
    manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in
    physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in
    an autocrine manner via activation of the receptor for activated glycation end products (RAGE)

         Genatlas biochemistry entry for S100P:
    S100 calcium binding protein P

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000287magnesium ion binding TAS15632002
    GO:0005509calcium ion binding IEA--
    GO:0005515protein binding IPI12042313
    GO:0048306calcium-dependent protein binding IPI15632002
    GO:0050786RAGE receptor binding ----
         
    S100P for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for S100P:
     Elongated cells with protrusio  Increased HPV18 LCR reporter a 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for S100P
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for S100P
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for S100P

    miRNA
    Products:
        
    miRTarBase miRNAs that target S100P:
    hsa-mir-24-3p (MIRT030424), hsa-mir-26b-5p (MIRT029220)

    Block miRNA regulation of human, mouse, rat S100P using miScript Target Protectors
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    GenScript: all cDNA clones in your preferred vector: S100P (NM_005980)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for S100P
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat S100P

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for S100P


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    S100P_HUMAN, P25815: Nucleus. Cytoplasm. Cell projection, microvillus membrane. Note=Colocalizes with S100PBP in
    the nucleus. Colocolizes with EZR in the microvilli in a calcium-dependent manner
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol3
    cytoskeleton2
    extracellular1
    mitochondrion1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA15632002
    GO:0005737cytoplasm TAS15632002
    GO:0031528microvillus membrane IEA--
    GO:0070062extracellular vesicular exosome IDA19056867

    S100P for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for S100P About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Gastric cancer network 1
    Gastric cancer network 1
    2Ca, cAMP and Lipid Signaling
    Ca, cAMP and Lipid Signaling

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for S100P
        Ca, cAMP and Lipid Signaling

    1 BioSystems Pathway for S100P
        Gastric cancer network 1




    S100P for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for S100P
    Interactions:

        GeneGlobe Interaction Network for S100P

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    Selected Interacting proteins for S100P (P258151, 2, 3 ENSP000002963704) via UniProtKB, MINT, STRING, and/or I2D (see all 22)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AGERQ151091, 3, ENSP000003642174EBI-743700,EBI-1646426 I2D: score=3 STRING: ENSP00000364217
    ENSG00000206320Q151091, 3EBI-743700,EBI-1646426 I2D: score=3 
    ENSG00000229058Q151091, 3EBI-743700,EBI-1646426 I2D: score=3 
    ENSG00000230514Q151091, 3EBI-743700,EBI-1646426 I2D: score=3 
    ENSG00000231268Q151091, 3EBI-743700,EBI-1646426 I2D: score=3 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0010033response to organic substance IEP17486081
    GO:0043542endothelial cell migration IMP15313892

    S100P for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for S100P

    1 HMDB Compound for S100P    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    1 DrugBank Compound for S100P    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Cromoglicic acidAcide Cromoglicique [INN-French] (see all 7)16110-51-3targetantagonist17179482



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for S100P gene: 
    NM_005980.2  

    Unigene Cluster for S100P:

    S100 calcium binding protein P
    Hs.2962  [show with all ESTs]
    Unigene Representative Sequence: BG571732
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000296370(uc003gjl.3) ENST00000513778
    miRNA
    Products:
         
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    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for S100P
    Predesigned siRNA for gene silencing in human, mouse, rat S100P
    Clone
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    GenScript: all cDNA clones in your preferred vector: S100P (NM_005980)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat S100P
    Primer
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    OriGene qPCR primer pairs and template standards for S100P
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    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat S100P
      QuantiTect SYBR Green Assays in human, mouse, rat S100P
      QuantiFast Probe-based Assays in human, mouse, rat S100P

    Additional mRNA sequence: 

    AY423724.1 BC006819.1 BT007289.1 X65614.1 

    5 DOTS entries:

    DT.100033798  DT.117002  DT.91859610  DT.121276401  DT.97859416 

    Selected AceView cDNA sequences (see all 179):

    AA369141 AA369104 AA587763 AJ706215 AA039888 BM856101 BM817911 BM851677 
    AI126103 CB138690 BM756650 NM_005980 BM765090 BE536069 BM852652 AI803595 
    AI023329 X65614 AA486010 AI148603 BC006819 CB138736 BM829138 BM766535 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    S100P expression in normal human tissues (normalized intensities)      S100P embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TACCTCTGAT
    S100P Expression
    About this image


    S100P expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 6 entries
             Bone Marrow
             Chondrocyte-like cells
     
     Cartilage (Muscoskeletal System)    fully expand to see all 5 entries
             Chondrocyte-like cells
     
     Placenta (Extraembryonic Tissues)
             Syncytiotrophoblast-like cells
     
     Blood (Hematopoietic System)
             Granulocytes Peripheral Blood
     
     Trophoblast (Extraembryonic Tissues)
             Mural Trophectoderm Cells Mural Trophectoderm
    S100P Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    S100P Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.2962

    UniProtKB/Swiss-Prot: S100P_HUMAN, P25815
    Tissue specificity: Detected in all of the tissues except brain, testis and small intestine, expression level is
    higher in placenta, heart, lung, skeletal muscle, spleen and leukocyte. Up-regulated in various pancreatic ductal
    adenocarcinomas and pancreatic intraepithelial neoplasias

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for S100P

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for S100P gene from Selected species (see all 5)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    dog
    (Canis familiaris)
    Mammalia S100P1 S100 calcium binding protein P 81.56(n)
    81.91(a)
      610295  XM_847763.3  XP_852856.2 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia s100p1 S100 calcium binding protein P 69.29(n)
    67.42(a)
      100135110  XM_002938260.2  XP_002938306.1 
    zebrafish
    (Danio rerio)
    Actinopterygii icn6
    icn26
    (see all 4)
    ictacalcin 2
    (see all 4)
    44(a)
    42(a)
    (see all 4)
    1 ↔ many
    1 ↔ many
    (see all 4)
    16(25670482-25671845) ENSDARG00000009978
    16(25726344-25730386) ENSDARG00000055514


    ENSEMBL Gene Tree for S100P (if available)
    TreeFam Gene Tree for S100P (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for S100P gene
    S100A112  S100A62  S100A12  S100A122  S100B2  S100A42  S100A32  S100A102  
    S100Z2  S100A22  S100A52  S100A92  
    Selected SIMAP similar genes for S100P using alignment to 1 protein entry:     S100P_HUMAN(see all similar genes):
    S100A1    S100A9    S100B    S100A4    S100Z    S100A16
    S100A6    S100G    S100A10    S100A2    S100A11    S100A12
    FLG2    RPTN    S100A13    TCHH    S100A5    S100A8

    S100P for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for S100P (see all 194)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs732117331,2
    C--6672935(+) AAACCC/TCCAAA 1 -- us2k15Minor allele frequency- T:0.19WA CSA NA EA 362
    rs76630571,2
    C,F--6673018(+) aaaccG/Aggaag 1 -- us2k12Minor allele frequency- A:0.08CSA WA 119
    rs357764461,2
    C--6673092(+) CATCGCAAA/-  
            
    CAAAC
    1 -- us2k11Minor allele frequency- -:0.50CSA 2
    rs1477081721,2
    --6673111(+) AACAA-/ACAAAAA 1 -- us2k10--------
    rs711734591,2
    C--6673112(+) ACAAA-/CAAA  
            
    AAATA
    1 -- us2k11Minor allele frequency- CAAA:0.00NA 2
    rs2015734281,2
    --6673117(+) AAAAA-/ATATATA 1 -- us2k10--------
    rs2008051171,2
    --6673133(+) GTGTA-/TATC  
            
    TATAT
    1 -- us2k10--------
    rs750078841,2
    C--6673146(+) TATATA/GTGTGT 1 -- us2k10--------
    rs2007028781,2
    --6673151(+) ATGTG-/TGTGTA
            
    TATAC
    1 -- us2k10--------
    rs1883198531,2
    --6673157(+) GTGTAC/TATACA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for S100P (6694796 - 6698897 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for S100P:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv829849CNV Loss17160897
    esv34196OTHER Inversion12058347

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 600614    OMIM disorders: --

    Selected diseases for S100P (see all 24):    About MalaCards
    parachordoma    pancreatic ductal adenocarcinoma    lung adenocarcinoma    prostate cancer
    bile duct carcinoma    pleomorphic adenoma    prostatitis    endometriosis
    pancreatitis    pancreatic cancer    intrahepatic cholangiocarcinoma    adenocarcinoma
    ischemia    cholangiocarcinoma    ovarian cancer    myocardial infarction
    hepatocellular carcinoma    adenoma    lung cancer    cervicitis

    2 diseases from the University of Copenhagen DISEASES database for S100P:
    Pancreatic cancer     Parachordoma

    S100P for disorders           About GeneDecksing


    Export disorders for S100P gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for S100P gene, integrated from 10 sources (see all 79):
    (articles sorted by number of sources associating them with S100P)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of the tissue-specific expression of the s100P gene which encodes an EF-hand Ca2+-binding protein. (PubMed id 14672411)1, 2, 9 Jin G.... Mao Y. (Mol. Biol. Rep. 2003)
    2. Generation and characterization of a novel, permanently active S100P mutant. (PubMed id 19111582)1, 2 Austermann J....Gerke V. (Biochim. Biophys. Acta 2009)
    3. Expression of S100P and its novel binding partner S100PBPR in early pancreatic cancer. (PubMed id 15632002)1, 2 Dowen S.E....Lemoine N.R. (Am. J. Pathol. 2005)
    4. NMR structure of the Apo-S100P protein. (PubMed id 15213440)1, 2 Lee Y.C.... Luxon B.A. (J. Biomol. NMR 2004)
    5. S100P stimulates cell proliferation and survival via receptor for activated glycation end products (RAGE). (PubMed id 14617629)1, 2 Arumugam T.... Logsdon C.D. (J. Biol. Chem. 2004)
    6. Heterodimeric interaction and interfaces of S100A1 and S100P. (PubMed id 15171681)1, 2 Wang G.... Barraclough R. (Biochem. J. 2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Ca2+-dependent binding and activation of dormant ezrin by dimeric S100P. (PubMed id 12808036)1, 2 Koltzscher M.... Gerke V. (Mol. Biol. Cell 2003)
    9. The crystal structure at 2A resolution of the Ca2+ -binding protein S100P. (PubMed id 12507480)1, 2 Zhang H.... Rao Z. (J. Mol. Biol. 2003)
    10. Isolation of a YAC clone covering a cluster of nine S100 genes on human chromosome 1q21: rationale for a new nomenclature of the S100 calcium-binding protein family. (PubMed id 7759097)1, 3 SchAofer B.W....Heizmann C.W. (Genomics 1995)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 6286 HGNC: 10504 AceView: S100P Ensembl:ENSG00000163993 euGenes: HUgn6286
    ECgene: S100P H-InvDB: S100P

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for S100P Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for S100P Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for S100P gene:
    Search GeneIP for patents involving S100P

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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