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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

S100P Gene

protein-coding   GIFtS: 63
GCID: GC04P006698

S100 Calcium Binding Protein P

(Previous name: S100 calcium-binding protein P)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
S100 Calcium Binding Protein P1 2     MIG92 3
S100 Calcium-Binding Protein P1 2 3     Protein S100-P2
Migration-Inducing Gene 9 Protein2 3     S100E3
Protein S100-E2 3     

External Ids:    HGNC: 105041   Entrez Gene: 62862   Ensembl: ENSG000001639937   OMIM: 6006145   UniProtKB: P258153   
ORGUL members:         
NONCODE14:n339830      

Export aliases for S100P gene to outside databases

Previous GC identifers: GC04M006590 GC04P006816 GC04P006687 GC04P006759 GC04P006812 GC04P006695 GC04P006628 GC04P006696


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for S100P Gene:
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding
motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the
regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes
include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at
4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the
etiology of prostate cancer. (provided by RefSeq, Jul 2008)

GeneCards Summary for S100P Gene: 
S100P (S100 calcium binding protein P) is a protein-coding gene, and is affiliated with the lncRNA class. Diseases associated with S100P include pancreatic ductal adenocarcinoma, and non-small cell lung carcinoma. GO annotations related to this gene include calcium-dependent protein binding and calcium ion binding. An important paralog of this gene is S100A11.

UniProtKB/Swiss-Prot: S100P_HUMAN, P25815
Function: May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated
glycation end products (RAGE)

Gene Wiki entry for S100P Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.2  NT_006051.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the S100P gene promoter:
         AREB6   NF-kappaB   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): S100P promoter sequence
   Search SABiosciences Chromatin IP Primers for S100P

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat S100P


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4p16   Ensembl cytogenetic band:  4p16.1   HGNC cytogenetic band: 4p16

S100P Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
S100P gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P006698:  view genomic region     (about GC identifiers)

Start:
6,694,796 bp from pter      End:
6,698,897 bp from pter
Size:
4,102 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: S100P_HUMAN, P25815 (See protein sequence)
Recommended Name: Protein S100-P  
Size: 95 amino acids; 10400 Da
Subunit: Homodimer and heterodimer with S100A1. Interacts with S100PBP and S100Z. Interacts with CACYBP in a
calcium-dependent manner. Dimeric form binds to and may activate EZR/Ezrin by unmasking its F-actin binding sites
Subcellular location: Nucleus. Cytoplasm. Note=Colocalizes with S100PBP in the nucleus
Miscellaneous: This protein binds two calcium ions
Sequence caution: Sequence=AAS00487.1; Type=Miscellaneous discrepancy; Note=Sequencing error in Met-1 codon;
2 PDB 3D structures from and Proteopedia for S100P:
1J55 (3D)        1OZO (3D)    
Secondary accessions: Q5J7W2

Explore the universe of human proteins at neXtProt for S100P: NX_P25815

Explore proteomics data for S100P at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P25815

  • S100P Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    S100P Protein Expression
    REFSEQ proteins: NP_005971.1  
    ENSEMBL proteins: 
     ENSP00000296370  

    Human Recombinant Protein Products for S100P: 
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    OriGene MassSpec for S100P 
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    Novus Biologicals S100P Proteins
    Novus Biologicals S100P Lysates
    Sino Biological Recombinant Protein for S100P
    Browse Sino Biological Cell Lysates 
    ProSpec Recombinant Protein for S100P
    Cloud-Clone Corp. Proteins for S100P 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA15632002
    GO:0005737cytoplasm TAS15632002
    GO:0031528microvillus membrane IEA--

    S100P for ontologies           About GeneDecksing



    S100P Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    EFHAND: EF-hand domain containing
    S100: S100 calcium binding proteins

    4 InterPro protein domains:
     IPR011992 EF-hand-like_dom
     IPR002048 EF_hand_dom
     IPR013787 S100_Ca-bd_sub
     IPR001751 S100/CaBP-9k_CS

    Graphical View of Domain Structure for InterPro Entry P25815

    ProtoNet protein and cluster: P25815

    1 Blocks protein domain: IPB001751 Calcium-binding protein

    UniProtKB/Swiss-Prot: S100P_HUMAN, P25815
    Similarity: Belongs to the S-100 family
    Similarity: Contains 2 EF-hand domains


    S100P for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: S100P_HUMAN, P25815
    Function: May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated
    glycation end products (RAGE)

         Genatlas biochemistry entry for S100P:
    S100 calcium binding protein P

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000287magnesium ion binding TAS15632002
    GO:0005509calcium ion binding IEA--
    GO:0005515protein binding IPI12042313
    GO:0048306calcium-dependent protein binding IPI15632002
         
    S100P for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for S100P:
     Elongated cells with protrusio  Increased HPV18 LCR reporter a 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for S100P 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for S100P

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for S100P 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for S100P 

    miRNA
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    Products:
        
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    Gene Editing
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    Clone
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for S100P


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for S100P About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Gastric cancer network 1
    Gastric cancer network 1
    2"Ca, cAMP and Lipid Signaling"
    "Ca, cAMP and Lipid Signaling"

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for S100P
        Ca, cAMP and Lipid Signaling

    1 BioSystems Pathway for S100P
        Gastric cancer network 1




    S100P for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for S100P

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    5/22 Interacting proteins for S100P (P258151, 2, 3 ENSP000002963704) via UniProtKB, MINT, STRING, and/or I2D (see all 22)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AGERQ151091, 3, ENSP000003642174EBI-743700,EBI-1646426 I2D: score=3 STRING: ENSP00000364217
    ENSG00000206320Q151091, 3EBI-743700,EBI-1646426 I2D: score=3 
    ENSG00000229058Q151091, 3EBI-743700,EBI-1646426 I2D: score=3 
    ENSG00000230514Q151091, 3EBI-743700,EBI-1646426 I2D: score=3 
    ENSG00000231268Q151091, 3EBI-743700,EBI-1646426 I2D: score=3 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0010033response to organic substance IEP17486081
    GO:0043542endothelial cell migration IMP15313892

    S100P for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for S100P

    1 HMDB Compound for S100P    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    1 DrugBank Compound for S100P    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Cromoglicic acidAcide Cromoglicique [INN-French] (see all 7)16110-51-3targetantagonist17179482

    Search CenterWatch for drugs/clinical trials and news about S100P

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for S100P gene: 
    NM_005980.2  

    Unigene Cluster for S100P:

    S100 calcium binding protein P
    Hs.2962  [show with all ESTs]
    Unigene Representative Sequence: BG571732
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000296370(uc003gjl.3) ENST00000513778
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat S100P
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate S100P
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for S100P
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat S100P
    Clone
    Products:
         
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: S100P (NM_005980)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for S100P
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat S100P
    Sirion Biotech Customized lentivirus for stable overexpression of S100P 
                         Customized lentivirus expression plasmids for stable overexpression of S100P 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for S100P
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    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat S100P
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat S100P
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat S100P

    Additional mRNA sequence: 

    AY423724.1 BC006819.1 BT007289.1 X65614.1 

    5 DOTS entries:

    DT.100033798  DT.117002  DT.91859610  DT.121276401  DT.97859416 

    24/179 AceView cDNA sequences (see all 179):

    AA369104 AA369141 BM851677 BM855906 AF539739 X65614 BM850689 BM850792 
    BM854679 BM756238 BM850623 BM782257 BM748812 BM756382 AI148603 AA039888 
    AI433932 BM848333 BM829138 AA486010 BM756243 BM765018 BE784569 BG059275 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    S100P expression in normal human tissues (normalized intensities)      S100P embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TACCTCTGAT
    S100P Expression
    About this image


    S100P expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/18 selected tissues (see all 18) fully expand
     
     Epithelium (Uncategorized)    fully expand to see all 7 entries
             Human Bronchial Epithelial Cells (HBEpiC)   
     
     Lung (Respiratory System)    fully expand to see all 6 entries
             Human Bronchial Epithelial Cells (HBEpiC)   
             Trachea   
     
     Bone (Muscoskeletal System)    fully expand to see all 5 entries
             Bone Marrow
             HyStem+BMP4-induced 4D20.8 cells
     
     Cartilage (Muscoskeletal System)    fully expand to see all 4 entries
             HyStem+BMP4-induced 4D20.8 cells
     
     Liver (Hepatobiliary System)    fully expand to see all 2 entries
             Human Hepatocyte (HH)   

    See S100P Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for S100P

    SOURCE GeneReport for Unigene cluster: Hs.2962

    UniProtKB/Swiss-Prot: S100P_HUMAN, P25815
    Tissue specificity: Detected in all of the tissues except brain, testis and small intestine, expression level is
    higher in placenta, heart, lung, skeletal muscle, spleen and leukocyte. Up-regulated in various pancreatic ductal
    adenocarcinomas and pancreatic intraepithelial neoplasias

        SABiosciences Custom PCR Arrays for S100P
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for S100P

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of mammals.

    Orthologs for S100P gene from 1/3 species (see all 3)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    dog
    (Canis familiaris)
    Mammalia S100P1 S100 calcium binding protein P 81.56(n)
    81.91(a)
      610295  XM_847763.2  XP_852856.2 


    ENSEMBL Gene Tree for S100P (if available)
    TreeFam Gene Tree for S100P (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for S100P gene
    S100A112  S100A62  S100A12  S100A122  S100B2  S100A42  S100A32  S100A102  
    S100Z2  S100A22  S100A52  S100A92  
    18/20 SIMAP similar genes for S100P using alignment to 1 protein entry:     S100P_HUMAN(see all similar genes):
    S100A1    S100A9    S100B    S100A4    S100Z    S100A16
    S100A6    S100G    S100A10    S100A2    S100A11    S100A12
    FLG2    RPTN    S100A13    TCHH    S100A5    S100A8

    S100P for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/194 SNPs in S100P are shown (see all 194)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs732117331,2
    C--6672935(+) AAACCC/TCCAAA 1 -- us2k15Minor allele frequency- T:0.19WA CSA NA EA 362
    rs76630571,2
    C,F--6673018(+) aaaccG/Aggaag 1 -- us2k12Minor allele frequency- A:0.08CSA WA 119
    rs357764461,2
    C--6673092(+) CATCGCAAA/-  
            
    CAAAC
    1 -- us2k11Minor allele frequency- -:0.50CSA 2
    rs1477081721,2
    --6673111(+) AACAA-/ACAAAAA 1 -- us2k10--------
    rs711734591,2
    C--6673112(+) ACAAA-/CAAA  
            
    AAATA
    1 -- us2k11Minor allele frequency- CAAA:0.00NA 2
    rs2015734281,2
    --6673117(+) AAAAA-/ATATATA 1 -- us2k10--------
    rs2008051171,2
    --6673133(+) GTGTA-/TATC  
            
    TATAT
    1 -- us2k10--------
    rs750078841,2
    C--6673146(+) TATATA/GTGTGT 1 -- us2k10--------
    rs2007028781,2
    --6673151(+) ATGTG-/TGTGTA
            
    TATAC
    1 -- us2k10--------
    rs1883198531,2
    --6673157(+) GTGTAC/TATACA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for S100P (6694796 - 6698897 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for S100P:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv829849CNV Loss17160897
    esv34196OTHER Inversion12058347

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing S100P
    DNA2.0 Custom Variant and Variant Library Synthesis for S100P

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 600614    OMIM disorders: --

    19 diseases for S100P:    About MalaCards
    pancreatic ductal adenocarcinoma    non-small cell lung carcinoma    prostate cancer, progression of    lung adenocarcinoma
    prostate cancer    prostatitis    pancreatic cancer    adenocarcinoma
    ischemia    pancreatitis    endometriosis    cholangiocarcinoma
    colon cancer    cervicitis    lung cancer    hepatocellular carcinoma
    adenoma    ovarian cancer    endotheliitis

    2 diseases from the University of Copenhagen DISEASES database for S100P:
    Pancreatic cancer     Parachordoma

    S100P for disorders           About GeneDecksing


    Export disorders for S100P gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for S100P gene, integrated from 9 sources (see all 75):
    (articles sorted by number of sources associating them with S100P)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of the tissue-specific expression of the s100P gene which encodes an EF-hand Ca2+-binding protein. (PubMed id 14672411)1, 2, 9 Jin G....Mao Y. (2003)
    2. Expression of S100P and its novel binding partner S100PBPR in early pancreatic cancer. (PubMed id 15632002)1, 2 Dowen S.E....Lemoine N.R. (2005)
    3. NMR structure of the Apo-S100P protein. (PubMed id 15213440)1, 2 Lee Y.C....Luxon B.A. (2004)
    4. S100P stimulates cell proliferation and survival via receptor for activated glycation end products (RAGE). (PubMed id 14617629)1, 2 Arumugam T....Logsdon C.D. (2004)
    5. Heterodimeric interaction and interfaces of S100A1 an d S100P. (PubMed id 15171681)1, 2 Wang G....Barraclough R. (2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Ca2+-dependent binding and activation of dormant ezrin by dimeric S100P. (PubMed id 12808036)1, 2 Koltzscher M....Gerke V. (2003)
    8. The crystal structure at 2A resolution of the Ca2+ -binding protein S100P. (PubMed id 12507480)1, 2 Zhang H.... Rao Z. (2003)
    9. Isolation of a YAC clone covering a cluster of nine S100 genes on human chromosome 1q21: rationale for a new nomenclature of the S100 calcium-binding protein family. (PubMed id 7759097)1, 3 Schafer B.W....Heizmann C.W. (1995)
    10. Six S100 genes are clustered on human chromosome 1q21: identification of two genes coding for the two previously unreported calcium-binding proteins S100D and S100E. (PubMed id 8341667)1, 3 Engelkamp D.... Heizmann C.W. (1993)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6286 HGNC: 10504 AceView: S100P Ensembl:ENSG00000163993 euGenes: HUgn6286
    ECgene: S100P H-InvDB: S100P

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for S100P Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for S100P Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for S100P gene:
    Search GeneIP for patents involving S100P

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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