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S100A9 Gene

protein-coding GIFtS: 60

GC01P151596

S100 calcium binding protein A9
(Previous names: S100 calcium-binding protein A9 (calgranulin B), S100 calcium binding protein A9 (calgranulin B) )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbols: CAGB, CFAG)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
60B8AG ^¹, ²
CAGB ^², ³, ⁵
CFAG ^², ³, ⁵
CGLB ^¹, ²
Calgranulin-B ^³
L1AG ^²
LIAG ^¹, ²
MAC387 ^¹, ²
MIF ^¹, ²
MRP-14 ^³
MRP14 ^¹, ², ³
NIF ^¹, ²
OTTHUMP00000015331 ^²
P14 ^¹, ², ³

Descriptions
Calprotectin L1H subunit ^³
Leukocyte L1 complex heavy chain ^³
Migration inhibitory factor-related protein 14 ^³
S100 calcium binding protein A9 ^²
S100 calcium binding protein A9 (calgranulin B) ^¹
S100 calcium-binding protein A9 ^², ³
S100 calcium-binding protein A9 (calgranulin B) ^¹, ²
calgranulin B ^²

External Ids
HGNC: 10499¹
Entrez Gene: 6280²
UniProtKB: P06702³
Ensembl: ENSG00000163220⁷

Search outside databases for aliases for S100A9 gene

Previous GC identifers: GC01P151146 GC01P149113 GC01P150105 GC01P150546 GC01P150143

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for S100A9:

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand

calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide

range of cells, and involved in the regulation of a number of cellular processes such as cell

cycle progression and differentiation. S100 genes include at least 13 members which are located as

a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and

altered expression of this protein is associated with the disease cystic fibrosis. [provided by

RefSeq]

UniProtKB/Swiss-Prot: S10A9_HUMAN, P06702

Function: Expressed by macrophages in acutely inflammated tissues and in chronic inflammations.

Seem to be an inhibitor of protein kinases. Also expressed in epithelial cells constitutively or

induced during dermatoses. May interact with components of the intermediate filaments in monocytes

and epithelial cells

Gene Wiki entry for S100A9

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the S100A9 gene

Entrez Gene cytogenetic band: 1q21 Ensembl cytogenetic band: 1q21.3 HGNC cytogenetic band: 1q21

S100A9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01P151596: (about GC identifiers)

Start:	151,596,954 bp from pter
End:	151,600,127 bp from pter
Size:	3,174 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000001.9 NT_004487.18

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: S10A9_HUMAN, P06702 (See protein sequence)

Recommended Name: Protein S100-A9

Size: 114 amino acids; 13242 Da

Subunit: Interacts with CEACAM3 in a calcium-dependent manner

Miscellaneous: Has been shown to bind calcium

PDB structure from and Proteopedia :

1IRJ (3D)

1XK4 (3D)

Secondary accessions: Q6FGA1 Q9NYM0 Q9UCJ1

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_002956.1

ENSEMBL proteins:

ENSP00000357727

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Macrophage L1 protein Calprotectin, MRP8 + MRP14, S100A9)
	Human Recombinant Proteins from Abnova (S100A9)

OriGene Purified Recombinant Human Protein: S100A9

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	18029348
GO:0005730	NOT nucleolus	IDA	18029348
GO:0005737	cytoplasm	IDA	18029348

About this table

Antibodies for S100A9:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for S100A9
	R&D Systems Antibodies for S100A9
	Antibodies from Abcam (Macrophage L1 protein Calprotectin, MRP8 + MRP14, S100A9), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (S100A9)
	Novus Biologicals Antibodies for S100A9

Assays for S100A9:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P06702

ProtoNet protein and cluster: P06702

1 Blocks protein family: IPB001751 Calcium-binding protein

UniProtKB/Swiss-Prot: S10A9_HUMAN, P06702

Similarity: Belongs to the S-100 family

Similarity: Contains 2 EF-hand domains

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (S100A9)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (S100A9)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002965

Applied Biosystems Silencer® siRNAs for S100A9

Sigma-Aldrich siRNA for S100A9

Sigma-Aldrich shRNA for S100A9

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for S100A9
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_002965
Myc/DDK tagged cDNA clone in CMV expression vector: NM_002965
untagged cDNA clone in CMV expression vector: NM_002965

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_002965

UniProtKB/Swiss-Prot: S10A9_HUMAN, P06702

Function: Expressed by macrophages in acutely inflammated tissues and in chronic inflammations.

Seem to be an inhibitor of protein kinases. Also expressed in epithelial cells constitutively or

induced during dermatoses. May interact with components of the intermediate filaments in monocytes

and epithelial cells

Genatlas biochemistry entry for S100A9:

S100 calcium binding protein A9,calgranulin B,epidermal differentiation complex expressed in

monocytes and granulocytes

3 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for S100a9):

homeostasis/metabolism

immune system

normal

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004871	signal transducer activity	TAS	3313057
GO:0005509	calcium ion binding	TAS	2149559
GO:0005515	protein binding	IPI	17353931 17620599

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for S100A9

5/48 Interacting proteins for S100A9 (P06702¹ ENSP00000357727³) via UniProtKB, MINT, and/or STRING (see all 48 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ARRB1	P49407¹	EBI-1055001, EBI-743313
ARRB2	P32121¹	EBI-1055001, EBI-714559
ILK	Q13418¹	EBI-1055001, EBI-747644
NUAK1	O60285¹	EBI-1055001, EBI-1046789
PAK7	Q9P286¹	EBI-1055001, EBI-1051061

About this table

5 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006954	inflammatory response	TAS	3313057
GO:0007267	cell-cell signaling	TAS	3313057
GO:0030595	leukocyte chemotaxis	IEA	--
GO:0031532	actin cytoskeleton reorganization	IEA	--
GO:0045113	regulation of integrin biosynthetic process	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for S100A9
10/23 Novoseek chemical compound relationships for S100A9 gene (see all 23 )

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
scca1	69.15	4	16035113 (2), 16273201 (1), 17638865 (1)
triethylene glycol dimethacrylate	46.55	3	14647409 (1), 12874078 (1)
monosodium urate	40.08	2	12905486 (2)
calcium	28.91	50	10536818 (3), 8053890 (2), 8558004 (2), 8499645 (2) (see all 23)
arachidonic acid	21.23	8	12553726 (2), 8898915 (1), 17135363 (1), 17429438 (1) (see all 6)
1,25 dihydroxy vitamin d3	20.92	3	10212853 (1), 2292594 (1), 8499645 (1)
orthophosphate	18.60	1	15905572 (1)
zinc	14.87	6	12167632 (1), 18755861 (1), 12874078 (1), 8645219 (1)
glyceraldehyde 3-phosphate	13.63	4	17722226 (1), 11489294 (1), 15355353 (1)
cytochalasin b	11.55	1	8898915 (1)

About this table

2 PharmGKB drug compound relationships for S100A9 gene

Drug compound	PharmGKB Relations	PubMed IDs for articles supporting these relationships
mercaptopurine	PD FA GN	12704389
methotrexate	PD FA GN	12704389

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (S100A9)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (S100A9)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002965

Sigma-Aldrich siRNA for S100A9

Sigma-Aldrich shRNA for S100A9

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_002965

REFSEQ mRNAs for S100A9 gene:

NM_002965.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_002965

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_002965
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_002965
                                 untagged cDNA clone in CMV expression vector: NM_002965

Additional cDNA sequence:

AF086362.1 AK311882.1 BC047681.2 CR542207.1 CR542224.1 M26311.1 X06233.1

6 DOTS entries:

DT.215083 DT.91908747 DT.95259360 DT.92432962 DT.95240936 DT.95259359

24/244 AceView cDNA sequences (see all 244 ):

AW449213 BU681394 BU540419 BQ072542 BM681155 BQ774304 AJ705888 BI060803

BX644886 BI060870 BQ422337 BM712918 AJ712988 F26504 CR542207 BI060732

BC047681 H49366 BQ933527 AF086362 AJ705905 AJ346834 BI060709 BQ949176

highest scoring ESTs for S100A9:

AA320415 AA320692 AA321204 AA321506 AA581931 AA582314 AA582879 AA583762 AA583821 AA583933

Unigene Cluster for S100A9:

S100 calcium binding protein A9

Hs.112405 [show with all ESTs]

Unigene Representative Sequence: BQ927179

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for S100A9

ExUns:	1a	·	1b	^	2a	·	2b
SP1:			-
SP2:

About this scheme

ECgene alternative splicing isoforms for S100A9

1 Ensembl transcript including schematic representation:

ENST00000368738

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

S100A9 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for S100A9

¹ / ² / ³

3 probe-sets matching S100A9 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
41471_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	W72424	0.80	1.00	0.91	1
203535_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_002965	0.60	1.00	0.82	1
203535_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks S100A9 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GTGGCCACGG

SOURCE GeneReport for Unigene cluster: Hs.112405
Expression variation in blood from EXPOLDB for S100A9

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for S100A9 gene from 5 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	S100A9¹	--	S100 calcium binding protein A9	75.81(n) 66.37(a)	490463 XM_547585.2 XP_547585.2
chimpanzee (Pan troglodytes)	S100A9¹	--	S100 calcium binding protein A9	98.25(n) 99.12(a)	457998 XM_514430.2 XP_514430.1
cow (Bos taurus)	S100A9¹	--	S100 calcium binding protein A9	78.07(n) 70.18(a)	532569 NM_001046328.1 NP_001039793.1
rat (Rattus norvegicus)	S100a9¹	--	S100 calcium binding protein A9	71.7(n) 65.09(a)	94195 NM_053587.1 NP_446039.1
mouse (Mus musculus)	S100a9^{1, 5}	3 (43.60 cM)⁵	S100 calcium binding protein A9 (calgranulin B)^{1, 5}	71.7(n)¹ 60.38(a)¹	20202¹ NM_009114.2¹ NP_033140.1¹ AJ250496⁵ AK143826⁵ (see all 11)

About this table Species with no ortholog for S100A9

ENSEMBL Gene Tree for S100A9

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for S100A9 gene

S100A12² S100A8² S100P²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/31 NCBI SNPs in S100A9 are shown (see all 31 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 69)

AB	SNP ID	Valid	Chr 1 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs3014866^1,2	A,C,F,H,O	151595695(+)	`GTGTCC/TCTCTT`	1	--	ng5¹		15	NA EU EA WA	1342
	rs2070864^1,2	A,C,F,H,O	151600424(+)	`CAAAAA/GGGCAT`	1	--	ng3¹		8	EA NA EU WA	2030
	rs2916197^1,2	A,C,F,H	151594959(-)	`ATGAAT/CGGTGC`	1	--	ng5¹		8	EU EA WA NA	628
	rs11205276^1,2	A,C,F,H	151595508(+)	`GGAAGG/CCTTCA`	1	--	ng5¹		8	EU EA WA	840
	rs12119788^1,2	C,F,H	151596802(+)	`AAGGCG/ACTCTG`	1	--	ng5¹		8	EU EA WA	838
	rs2916196^1,2	C,F,H	151594971(-)	`GCCTAT/CGAATG`	1	--	ng5¹		12	EU EA WA NS NA	654
	rs6691934^1,2	A,F,H	151595195(+)	`gttgcA/Gtaaat`	1	--	ng5¹ tfbs³		2	EA	156
	rs3014868^1,2	F,H	151600129(+)	`GTCAGT/CGCTCT`	1	--	ng3¹		4	EU EA WA	418
	rs1063933^1,2	C	151599879(+)	`TGCACG/AAGGGT`	1	K/E	mis¹ ese³		1	MN	184
	rs9988616^1,2	A,F,H	151598183(+)	`TCCCCC/TGCTCC`	1	--	int¹ trp³		4	EU EA WA	406

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HapMap Linkage Disequilibrium images for S100A9 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 123886

10/50 Novoseek disease relationships for S100A9 gene (see all 50 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
inflammation	52.60	31	1524561 (2), 17138858 (2), 1490735 (2), 9549523 (1) (see all 23)
psoriasis	46.17	7	16792753 (2), 11493312 (1), 12704215 (1), 15740587 (1) (see all 6)
inflammatory bowel diseases	40.57	2	9759608 (1), 17553524 (1)
cystic fibrosis	36.59	11	7517672 (2), 7762618 (2), 15901828 (1), 2292594 (1) (see all 7)
spondylarthropathies	33.89	1	12794836 (1)
rheumatoid arthritis	29.96	6	16613612 (1), 12794836 (1), 2292594 (1), 17553524 (1) (see all 6)
dermatomyositis	29.23	2	2292594 (1), 12937135 (1)
mixed connective tissue disease	26.52	1	2292594 (1)
sclerosis systemic	26.17	1	2292594 (1)
polymyositis	24.95	2	2292594 (1), 12937135 (1)

About this table

1 PharmGKB disease relationship for S100A9 gene

Disease	PharmGKB Relations	PubMed IDs for articles supporting these relationships
Leukemia, Lymphocytic, Acute, L1	PD FA GN	12704389

About this table

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/291 PubMed articles for S100A9 gene (see all 291 ):

The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)^{3, 4} Gregory S.G.... Bentley D.R. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
The microbial receptor CEACAM3 is linked to the calprotectin complex in granulocytes. (PubMed id 11708798)^{3, 4} Streichert T....Bruemmer J. (2001)
In vitro antimicrobial activity of the human neutrophil cytosolic S- 100 protein complex, calprotectin, against Capnocytophaga sputigena. (PubMed id 8423249)^{3, 4} Miyasaki K.T.... Lehrer R.I. (1993)
Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes. (PubMed id 1286667)^{3, 4} Rasmussen H.H....Vandekerckhove J. (1992)
Ionomycin-regulated phosphorylation of the myeloid calcium-binding protein p14. (PubMed id 2478889)^{3, 4} Edgeworth J.... Hogg N. (1989)
A protein containing the cystic fibrosis antigen is an inhibitor of protein kinases. (PubMed id 2656677)^{3, 4} Murao S.... Huberman E. (1989)
Cloning and expression of two human genes encoding calcium-binding proteins that are regulated during myeloid differentiation. (PubMed id 3405210)^{3, 4} Lagasse E. and Clerc R.G. (1988)
Two calcium-binding proteins in infiltrate macrophages of rheumatoid arthritis. (PubMed id 3313057)^{3, 4} Odink K.... Sorg C. (1987)
Expression of MRP14 gene is frequently down-regulated in Chinese human esophageal cancer. (PubMed id 15040889)^{1, 3} Wang J....Wang M.R. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 6280	HGNC: 10499	AceView: S100A9	Ensembl:ENSG00000163220	euGenes: HUgn6280
ECgene: S100A9	H-InvDB: S100A9

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for S100A9
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for S100A9:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for S100A9-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for S100A9		Antibodies for S100A9
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for S100A9		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (S100A9)
	Antibodies (S100A9)
	Chimera RNAi (S100A9)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (Macrophage L1 protein Calprotectin, MRP8 + MRP14, S100A9)
	Antibodies (Macrophage L1 protein Calprotectin, MRP8 + MRP14, S100A9)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

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Antibodies for S100A9

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S100A9 Gene

protein-coding GIFtS: 60

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for S100A9

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for S100A9

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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

S100A9 (Gene Symbol)
60B8AG
CAGB
CFAG
CGLB
Calgranulin-B
L1AG
LIAG
MAC387
MIF
MRP-14
MRP14
NIF
OTTHUMP00000015331
P14
Calprotectin L1H subunit
Leukocyte L1 complex heavy chain
Migration inhibitory factor-related protein 14
S100 calcium binding protein A9
S100 calcium binding protein A9 (calgranulin B)
S100 calcium-binding protein A9
S100 calcium-binding protein A9 (calgranulin B)
calgranulin B

S100A9 Gene

protein-coding GIFtS: 60

Aliases & Descriptionsfor S100A9

Summariesfor S100A9

Genomic Locationfor S100A9

Proteinsfor S100A9

Protein Domains/Familiesfor S100A9

Gene Functionfor S100A9

Pathways & Interactionsfor S100A9

Drugs & Compoundsfor S100A9

Transcriptsfor S100A9

Expression for S100A9

Orthologsfor S100A9

Paralogsfor S100A9

SNPs/Variantsfor S100A9

Disorders & Mutationsfor S100A9

Medical Newsfor S100A9

Publicationsfor S100A9

Search for S100A9

Genome Databases showing S100A9

Other Databases showing S100A9

Specialized Databases showing S100A9

Licensable Technologiesfor S100A9

Servicesfor S100A9

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for S100A9

Summaries
for S100A9

Genomic Location
for S100A9

Proteins
for S100A9

Protein Domains/
Families
for S100A9

Gene Function
for S100A9

Pathways & Interactions
for S100A9

Drugs & Compounds
for S100A9

Transcripts
for S100A9

Expression
for S100A9

Orthologs
for S100A9

Paralogs
for S100A9

SNPs/Variants
for S100A9

Disorders & Mutations
for S100A9

Medical News
for S100A9

Publications
for S100A9

Licensable Technologies
for S100A9

Services
for S100A9