Free for academic non-profit institutions. Other users need a Commercial license

Aliases for S100A7L2 Gene

Aliases for S100A7L2 Gene

  • S100 Calcium Binding Protein A7 Like 2 2 3 5
  • S100a7b 3 4
  • S100 Calcium Binding Protein A7-Like 2 2
  • S100 Calcium-Binding Protein A7-Like 2 4
  • Protein S100-A7-Like 2 3

External Ids for S100A7L2 Gene

Previous GeneCards Identifiers for S100A7L2 Gene

  • GC01M150626
  • GC01U901079
  • GC01M151677
  • GC01M124772

Summaries for S100A7L2 Gene

GeneCards Summary for S100A7L2 Gene

S100A7L2 (S100 Calcium Binding Protein A7 Like 2) is a Protein Coding gene. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is S100A7A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for S100A7L2 Gene

Genomics for S100A7L2 Gene

Regulatory Elements for S100A7L2 Gene

Enhancers for S100A7L2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F153577 1.6 FANTOM5 Ensembl ENCODE 11.1 -138.3 -138333 2.7 CTCF KLF1 JUN KLF17 ZIC2 ZNF664 FOSL1 ZNF121 ZFHX2 GATA3 S100A3 S100A16 S100A14 S100A1 S100A13 CHTOP S100A7L2 SNAPIN ILF2 NPR1
GH01F153552 1.6 FANTOM5 Ensembl ENCODE 5.7 -113.7 -113674 2.6 CTCF HDAC1 FEZF1 DMAP1 ZFHX2 ZNF766 ZNF366 POLR2A ZBTB48 PRDM10 S100A3 CHTOP S100A13 S100A16 S100A14 S100A1 INTS3 ENSG00000233222 ENSG00000243613 ILF2
GH01F153531 1 FANTOM5 ENCODE 5.3 -95.1 -95104 8.2 HDGF PKNOX1 CREB3L1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZNF143 FOS S100A3 INTS3 CHTOP ENSG00000272654 RN7SL44P S100A7L2 PGLYRP3 SLC39A1 PIR41635 S100A6
GH01F153572 1.3 FANTOM5 Ensembl ENCODE 2.6 -132.8 -132774 2.4 ATF1 PKNOX1 ARID4B SIN3A DMAP1 ZNF48 GLIS2 CBX5 ZNF143 KLF7 S100A3 S100A9 S100A7L2 S100A12 S100A4 S100A2 PIR44602
GH01F153561 1.3 FANTOM5 ENCODE 2.4 -125.5 -125535 8.8 HDGF PKNOX1 WRNIP1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF207 ZNF143 INTS3 S100A6 S100A3 S100A5 ENSG00000238279 S100A16 S100A13 S100A14 ENSG00000272654 SNAPIN
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around S100A7L2 on UCSC Golden Path with GeneCards custom track

Genomic Location for S100A7L2 Gene

153,436,995 bp from pter
153,440,027 bp from pter
3,033 bases
Minus strand

Genomic View for S100A7L2 Gene

Genes around S100A7L2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
S100A7L2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for S100A7L2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for S100A7L2 Gene

Proteins for S100A7L2 Gene

  • Protein details for S100A7L2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein S100-A7-like 2
    Protein Accession:

    Protein attributes for S100A7L2 Gene

    101 amino acids
    Molecular mass:
    11302 Da
    Quaternary structure:
    No Data Available

neXtProt entry for S100A7L2 Gene

Post-translational modifications for S100A7L2 Gene

No Post-translational modifications

Other Protein References for S100A7L2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for S100A7L2 Gene

Domains & Families for S100A7L2 Gene

Gene Families for S100A7L2 Gene

Protein Domains for S100A7L2 Gene

Suggested Antigen Peptide Sequences for S100A7L2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 2 EF-hand domains.
  • Belongs to the S-100 family.
  • Contains 2 EF-hand domains.
  • Belongs to the S-100 family.
genes like me logo Genes that share domains with S100A7L2: view

Function for S100A7L2 Gene

Gene Ontology (GO) - Molecular Function for S100A7L2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005509 calcium ion binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with S100A7L2: view

Phenotypes for S100A7L2 Gene

genes like me logo Genes that share phenotypes with S100A7L2: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for S100A7L2 Gene

Localization for S100A7L2 Gene

Subcellular locations from

Jensen Localization Image for S100A7L2 Gene COMPARTMENTS Subcellular localization image for S100A7L2 gene
Compartment Confidence
cytosol 2
endoplasmic reticulum 1
extracellular 1
mitochondrion 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for S100A7L2 Gene

Pathways & Interactions for S100A7L2 Gene

SuperPathways for S100A7L2 Gene

No Data Available

Interacting Proteins for S100A7L2 Gene

Gene Ontology (GO) - Biological Process for S100A7L2 Gene


No data available for Pathways by source and SIGNOR curated interactions for S100A7L2 Gene

Transcripts for S100A7L2 Gene

mRNA/cDNA for S100A7L2 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for S100A7L2 Gene

No ASD Table

Relevant External Links for S100A7L2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for S100A7L2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for S100A7L2 Gene

Protein differential expression in normal tissues from HIPED for S100A7L2 Gene

This gene is overexpressed in Esophagus (65.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for S100A7L2 Gene

Protein tissue co-expression partners for S100A7L2 Gene

NURSA nuclear receptor signaling pathways regulating expression of S100A7L2 Gene:


SOURCE GeneReport for Unigene cluster for S100A7L2 Gene:

genes like me logo Genes that share expression patterns with S100A7L2: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for S100A7L2 Gene

Orthologs for S100A7L2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for S100A7L2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia S100A7L2 34 35
  • 99.7 (n)
(Bos Taurus)
Mammalia -- 35
  • 52 (a)
S100A7 35
  • 50 (a)
(Monodelphis domestica)
Mammalia -- 35
  • 25 (a)
Species where no ortholog for S100A7L2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for S100A7L2 Gene

Gene Tree for S100A7L2 (if available)
Gene Tree for S100A7L2 (if available)

Paralogs for S100A7L2 Gene

Paralogs for S100A7L2 Gene

(6) SIMAP similar genes for S100A7L2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with S100A7L2: view

Variants for S100A7L2 Gene

Sequence variations from dbSNP and Humsavar for S100A7L2 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs10888561 -- 153,438,346(+) AAAAG(A/C)CTTCA reference, missense
rs111432201 -- 153,437,242(+) ACACG(C/T)AAGAA intron-variant
rs111530393 -- 153,438,895(+) GAGCG(C/T)GGACA intron-variant
rs112403134 -- 153,438,288(+) ATCGC(A/G)ACTAT reference, synonymous-codon
rs112518869 -- 153,441,549(+) GGGGA(C/T)TGGGG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for S100A7L2 Gene

Variant ID Type Subtype PubMed ID
esv33204 CNV gain 17666407
nsv1002705 CNV gain 25217958
nsv831603 CNV gain 17160897

Variation tolerance for S100A7L2 Gene

Gene Damage Index Score: 2.17; 39.35% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for S100A7L2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for S100A7L2 Gene

Disorders for S100A7L2 Gene

Relevant External Links for S100A7L2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for S100A7L2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for S100A7L2 Gene

Publications for S100A7L2 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 64
  2. Genomic and phylogenetic analysis of the S100A7 (psoriasin) gene duplications within the region of the S100 gene cluster on human chromosome 1q21. (PMID: 12664160) Kulski J.K. … Bellgard M. (J. Mol. Evol. 2003) 3 4 64

Products for S100A7L2 Gene

Sources for S100A7L2 Gene

Loading form....