Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



S100A7A Gene

protein-coding   GIFtS: 47
GCID: GC01P153392

S100 Calcium Binding Protein A7A

(Previous names: S100 calcium binding protein A15, S100 calcium binding protein...)
(Previous symbols: S100A15, S100A7L1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
S100 Calcium Binding Protein A7A1 2     S100 Calcium-Binding Protein A7-Like 12 3
S100A151 2 3     S100 Calcium-Binding Protein A7A2 3
S100A7L11 2 3     NICE-22
S100 Calcium Binding Protein A151 2     S100A7f2
S100 Calcium Binding Protein A7-Like 11 2     Protein S100-A7A2
S100 Calcium-Binding Protein A152 3     

External Ids:    HGNC: 216571   Entrez Gene: 3383242   Ensembl: ENSG000001843307   UniProtKB: Q86SG53   

Export aliases for S100A7A gene to outside databases

Previous GC identifers: GC01P151655 GC01P124752


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for S100A7A Gene:
S100A7A (S100 calcium binding protein A7A) is a protein-coding gene. Diseases associated with S100A7A include psoriasis, and skin disease. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is S100A7.

UniProtKB/Swiss-Prot: S1A7A_HUMAN, Q86SG5
Function: May be involved in epidermal differentiation and inflammation and might therefore be important for the
pathogenesis of psoriasis and other diseases

Gene Wiki entry for S100A7A (S100A15) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000001.11  NT_004487.20  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the S100A7A gene promoter:
         COUP-TF1   LHX3b/Lhx3b   COUP   HNF-4alpha2   C/EBPalpha   HNF-4alpha1   COUP-TF   HOXA5   Chx10   LHX3a/Lhx3a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidS100A7A promoter sequence
   Search Chromatin IP Primers for S100A7A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat S100A7A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21.3   Ensembl cytogenetic band:  1q21.3   HGNC cytogenetic band: 1q22

S100A7A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
S100A7A gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P153392:  view genomic region     (about GC identifiers)

Start:
153,389,000 bp from pter      End:
153,395,701 bp from pter
Size:
6,702 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: S1A7A_HUMAN, Q86SG5 (See protein sequence)
Recommended Name: Protein S100-A7A  
Size: 101 amino acids; 11305 Da
1 PDB 3D structure from and Proteopedia for S100A7A:
4AQI (3D)    
Secondary accessions: D3DV38 Q5SY69

Explore the universe of human proteins at neXtProt for S100A7A: NX_Q86SG5

Explore proteomics data for S100A7A at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See S100A7A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_789793.1  
    ENSEMBL proteins: 
     ENSP00000357718   ENSP00000357717   ENSP00000329008  

    S100A7A Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for S100A7A
    OriGene Protein Over-expression Lysate for S100A7A
    OriGene MassSpec for S100A7A
    OriGene Custom Protein Services for S100A7A
    GenScript Custom Purified and Recombinant Proteins Services for S100A7A
    Novus Biologicals S100A7A Protein
    Novus Biologicals S100A7A Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for S100A7A
    Browse Proteins at Cloud-Clone Corp.

    S100A7A Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for S100A7A
    Abcam antibodies for S100A7A
    Browse Antibodies at Cloud-Clone Corp.
    Search ThermoFisher Antibodies for S100A7A
    LSBio Antibodies in human, mouse, rat for S100A7A

    S100A7A Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for S100A7A
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for S100A7A
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    EFHAND: EF-hand domain containing
    S100: S100 calcium binding proteins

    Selected InterPro protein domains (see all 6):
     IPR028477 S100A7
     IPR011992 EF-hand-dom_pair
     IPR002048 EF_hand_dom
     IPR013787 S100_Ca-bd_sub
     IPR018247 EF_Hand_1_Ca_BS

    Graphical View of Domain Structure for InterPro Entry Q86SG5

    ProtoNet protein and cluster: Q86SG5

    1 Blocks protein domain: IPB001751 Calcium-binding protein

    UniProtKB/Swiss-Prot: S1A7A_HUMAN, Q86SG5
    Similarity: Belongs to the S-100 family
    Similarity: Contains 2 EF-hand domains


    S100A7A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: S1A7A_HUMAN, Q86SG5
    Function: May be involved in epidermal differentiation and inflammation and might therefore be important for the
    pathogenesis of psoriasis and other diseases

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IEA--
    GO:0043621protein self-association ----
         
    S100A7A for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for S100A7A:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for S100A7A
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for S100A7A

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for S100A7A
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for S100A7A

    miRNA
    Products:
        
    miRTarBase miRNAs that target S100A7A:
    hsa-mir-26b-5p (MIRT030254)

    Block miRNA regulation of human, mouse, rat S100A7A using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate S100A7A
    SwitchGear 3'UTR luciferase reporter plasmidS100A7A 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for S100A7A
    Predesigned siRNA for gene silencing in human, mouse, rat S100A7A

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for S100A7A

    Clone
    Products:
         
    OriGene clones in human, mouse for S100A7A (see all 6)
    OriGene ORF clones in mouse, rat for S100A7A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: S100A7A (NM_176823)
    Sino Biological Human cDNA Clone for S100A7A
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for S100A7A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat S100A7A

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for S100A7A
    Browse ESI BIO Cell Lines and PureStem Progenitors for S100A7A 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for S100A7A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    S1A7A_HUMAN, Q86SG5: Cytoplasm (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus2
    extracellular1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--

    S100A7A for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus




        Pathway & Disease-focused RT2 Profiler PCR Arrays including S100A7A: 
              Necrosis in human mouse rat
              Molecular Toxicology PathwayFinder 384HT in human mouse rat
              Cell Death PathwayFinder in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for S100A7A

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for S100A7A (ENSP000003290084) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    COPS5ENSP000003505124STRING: ENSP00000350512
    FABP5ENSP000002972584STRING: ENSP00000297258
    S100A9ENSP000003577274STRING: ENSP00000357727
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for S100A7A (S1A7A)

    1 Novoseek inferred chemical compound relationship for S100A7A gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    calcium 18.9 3 17620096 (2), 16528363 (1)



    S100A7A for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for S100A7A gene: 
    NM_176823.3  

    Unigene Cluster for S100A7A:

    S100 calcium binding protein A7A
    Hs.442337  [show with all ESTs]
    Unigene Representative Sequence: AY189118
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000368729(uc001fbt.1) ENST00000368728 ENST00000329256
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat S100A7A using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate S100A7A
    SwitchGear 3'UTR luciferase reporter plasmidS100A7A 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for S100A7A
    Predesigned siRNA for gene silencing in human, mouse, rat S100A7A
    Clone
    Products:
         
    OriGene clones in human, mouse for S100A7A (see all 6)
    OriGene ORF clones in mouse, rat for S100A7A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: S100A7A (NM_176823)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for S100A7A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat S100A7A
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for S100A7A
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat S100A7A
      QuantiTect SYBR Green Assays in human, mouse, rat S100A7A
      QuantiFast Probe-based Assays in human, mouse, rat S100A7A

    Additional mRNA sequence: 

    AJ243672.2 AJ243673.1 AY189118.1 AY189119.1 BC040254.1 

    2 DOTS entries:

    DT.91670968  DT.111095 

    1 AceView cDNA sequence:

    AW176058 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    S100A7A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTCCCTTATA
    S100A7A Expression
    About this image


    S100A7A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Epithelial Cells
             Intermediate Keratinocytes Embryonic Epidermis
     
     Epidermis (Integumentary System)    fully expand to see all 3 entries
             Intermediate Keratinocytes Embryonic Epidermis
     
     Hair
             Primary Hair Placode Cells Hair Follicle
     
     Neural Tube (Nervous System)
             Spinal Ventral Columns
    S100A7A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    S100A7A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.442337

    UniProtKB/Swiss-Prot: S1A7A_HUMAN, Q86SG5
    Tissue specificity: Overexpressed in psoriasis

        Pathway & Disease-focused RT2 Profiler PCR Arrays including S100A7A: 
              Necrosis in human mouse rat
              Molecular Toxicology PathwayFinder 384HT in human mouse rat
              Cell Death PathwayFinder in human mouse rat

    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for S100A7A
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat S100A7A
    QuantiTect SYBR Green Assays in human, mouse, rat S100A7A
    QuantiFast Probe-based Assays in human, mouse, rat S100A7A
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for S100A7A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of human and mouse.

    Orthologs for S100A7A gene from Selected species (see all 5)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia S100a7a5 S100 calcium binding protein A7A   --   3 (39.82 cM) 90654302 


    ENSEMBL Gene Tree for S100A7A (if available)
    TreeFam Gene Tree for S100A7A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for S100A7A gene
    S100A72  S100A7L22  
    12 SIMAP similar genes for S100A7A using alignment to 1 protein entry:     S1A7A_HUMAN:
    S100A7    S100A7L2    S100A4    S100B    S100A6    S100Z
    S100A7L3    S100P    S100A12    S100A10    S100A11    S100A8

    S100A7A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for S100A7A (see all 288)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1429005881,2
    C--153387028(+) AAACAA/TCAATG 1 -- us2k10--------
    rs1462731731,2
    --153387032(+) AACAAC/TGAGAT 1 -- us2k10--------
    rs1884521961,2
    --153387176(+) CAGTTC/TGGTGC 1 -- us2k10--------
    rs1390314761,2
    C--153387196(+) AAACTA/GAACAT 1 -- us2k10--------
    rs1430420151,2
    --153387236(+) TCTTCA/GGGATT 1 -- us2k10--------
    rs115790411,2
    C,F,H--153387260(+) tgaaaG/Acttat 1 -- us2k18Minor allele frequency- A:0.09NA WA CSA EA 370
    rs800611961,2
    F--153387297(+) GTATAT/AGAACA 1 -- us2k11Minor allele frequency- A:0.10NA 120
    rs1814438851,2
    --153387315(+) CAGTGG/TTGAAG 1 -- us2k10--------
    rs1447240081,2
    --153387324(+) AGTCCA/GGGCTT 1 -- us2k10--------
    rs1860352781,2
    --153387355(+) AACACA/GCATTG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for S100A7A (153389000 - 153395701 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for S100A7A: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing S100A7A
    DNA2.0 Custom Variant and Variant Library Synthesis for S100A7A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    3 diseases for S100A7A:    
    About MalaCards
    psoriasis    skin disease    tonsillitis


    S100A7A for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for S100A7A gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    psoriasis 67.6 3 16682778 (2), 17620096 (1)


    Export disorders for S100A7A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for S100A7A gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with S100A7A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genomic and phylogenetic analysis of the S100A7 (psoriasin) gene duplications within the region of the S100 gene cluster on human chromosome 1q21. (PubMed id 12664160)1, 2, 9 Kulski J.K.... Bellgard M. (J. Mol. Evol. 2003)
    2. Molecular cloning and characterization of alternatively spliced mRNA isoforms from psoriatic skin encoding a novel member of the S100 family. (PubMed id 12923069)1, 2, 9 Wolf R.... Ruzicka T. (FASEB J. 2003)
    3. Structural characterization of S100A15 reveals a novel zinc coordination site among S100 proteins and altered surface chemistry with functional implications for receptor binding. (PubMed id 22747601)1, 2 Murray J.I.... Boulanger M.J. (BMC Struct. Biol. 2012)
    4. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    5. Identification of human epidermal differentiation complex (EDC)- encoded genes by subtractive hybridization of entire YACs to a gridded keratinocyte cDNA library. (PubMed id 11230159)1, 3 Marenholz I....Mischke D. (Genome Res. 2001)
    6. Purification, crystallization and preliminary X-ray diffraction of human S100A15. (PubMed id 16682778)1, 9 Boeshans K.M....Ahvazi B. (Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 2006)
    7. Human S100A15 splice variants are differentially expressed in inflammatory skin diseases and regulated through Th1 cytokines and calcium. (PubMed id 17620096)1, 9 Wolf R....Ruzicka T. (Exp. Dermatol. 2007)
    8. Chemotactic activity of S100A7 (Psoriasin) is mediated by the receptor for advanced glycation end products and potentiates inflammation with highly homologous but functionally distinct S100A15. (PubMed id 18606705)1 Wolf R....Yuspa S.H. (J. Immunol. 2008)
    9. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    10. S100A15, an antimicrobial protein of the skin: regulation by E. coli through Toll-like receptor 4. (PubMed id 17625598)1 BA1chau A.S....Ruzicka T. (J. Invest. Dermatol. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 338324 HGNC: 21657 AceView: S100A7L1.2 Ensembl:ENSG00000184330 euGenes: HUgn338324
    ECgene: S100A7A H-InvDB: S100A7A

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for S100A7A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for S100A7A gene:
    Search GeneIP for patents involving S100A7A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for S100A7A  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for S100A7A  
     OriGene MassSpec something-or-other for S100A7A   OriGene clones in human, mouse for S100A7A  
     OriGene qSTAR qPCR primer pairs in human, mouse for S100A7A   OriGene Purified Protein for S100A7A  
     OriGene ORF clones in mouse, rat for S100A7A   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for S100A7A   OriGene Custom Protein Services for S100A7A  

     
     
     Block miRNA regulation of human, mouse, rat S100A7A using miScript Target Protectors SeqTarget long-range PCR primers for resequencing S100A7A
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat S100A7A Predesigned siRNA for gene silencing in human, mouse, rat S100A7A
     QuantiFast Probe-based Assays in human, mouse, rat S100A7A QuantiTect SYBR Green Assays in human, mouse, rat S100A7A
     PCR Arrays including human, mouse / rat S100A7A Search Chromatin IP Primers for S100A7A
     Pre-validated RT2 qPCR Primer Assay in human, mouse / rat S100A7A  Search GeneGlobe Interaction Network for S100A7A
     Regulatory tfbs in S100A7A promoter
     GenScript Custom Purified and Recombinant Proteins Services for S100A7A GenScript cDNA clones with any tag delivered in your preferred vector for S100A7A
     GenScript Custom Assay Services for S100A7A GenScript Custom overexpressing Cell Line Services for S100A7A
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for S100A7A (S1A7A)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for S100A7A
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     S100A7A proteins
     S100A7A lysates
     Antibodies for S100A7A
     See all of Abcam's Antibodies, Kits and Proteins for S100A7A
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Recombinant Protein for S100A7A
     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.



     Browse ESI BIO Cell Lines and PureStem Progenitors for S100A7A
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for S100A7A
     SwitchGear 3'UTR luciferase reporter plasmids for S100A7A
     SwitchGear Promoter luciferase reporter plasmids for S100A7A
     Search ThermoFisher Antibodies for S100A7A
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat S100A7A
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for S100A7A
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for S100A7A
     LSBio Antibodies in human, mouse, rat for S100A7A
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      S100A7A gene at Home site.
    Version: 3.12.142 28 July 2014
    hostname: 356980-web2.xennexinc.com index build: 126 solr: 1.4