Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

S100A5 Gene

protein-coding   GIFtS: 55
GCID: GC01M153509

S100 Calcium Binding Protein A5

(Previous name: S100 calcium-binding protein A5)
(Previous symbol: S100D)
Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
S100 Calcium Binding Protein A51 2
S100D1 2 3 5
S100 Calcium-Binding Protein A51 2 3
Protein S100-A52
Protein S-100D3

External Ids:    HGNC: 104951   Entrez Gene: 62762   Ensembl: ENSG000001964207   OMIM: 1769915   UniProtKB: P337633   

Export aliases for S100A5 gene to outside databases

Previous GC identifers: GC01M151325 GC01M149292 GC01M150336 GC01M150778 GC01M150322 GC01M151776 GC01M124872


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for S100A5 Gene:
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding
motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the
regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes
include at least 13 members which are located as a cluster on chromosome 1q21. This protein has a Ca2+ affinity
20- to 100-fold higher than the other S100 proteins studied under identical conditions. This protein also binds
Zn2+ and Cu2+, and Cu2+ strongly which impairs the binding of Ca2+. This protein is expressed in very restricted
regions of the adult brain. (provided by RefSeq, Jul 2008)

GeneCards Summary for S100A5 Gene: 
S100A5 (S100 calcium binding protein A5) is a protein-coding gene. Diseases associated with S100A5 include anaplastic astrocytoma, and craniopharyngioma. GO annotations related to this gene include copper ion binding and calcium ion binding. An important paralog of this gene is S100A11.

UniProtKB/Swiss-Prot: S10A5_HUMAN, P33763
Function: Binds calcium, zinc and copper. One subunit can simultaneously bind 2 calcium ions or 2 copper ions plus
1 zinc ion. Calcium and copper ions compete for the same binding sites

Gene Wiki entry for S100A5 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_004487.19  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the S100A5 gene promoter:
         AML1a   ATF-2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidS100A5 promoter sequence
   Search SABiosciences Chromatin IP Primers for S100A5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat S100A5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21   Ensembl cytogenetic band:  1q21.3   HGNC cytogenetic band: 1q21

S100A5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
S100A5 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M153509:  view genomic region     (about GC identifiers)

Start:
153,509,623 bp from pter      End:
153,514,241 bp from pter
Size:
4,619 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: S10A5_HUMAN, P33763 (See protein sequence)
Recommended Name: Protein S100-A5  
Size: 92 amino acids; 10744 Da
Subunit: Homodimer
Sequence caution: Sequence=CAA79472.1; Type=Erroneous initiation; Sequence=CAA79475.1; Type=Erroneous initiation;
Sequence=CAA79479.1; Type=Erroneous initiation;
3 PDB 3D structures from and Proteopedia for S100A5:
2KAX (3D)        2KAY (3D)        4DIR (3D)    
Secondary accessions: Q5RHS3

Explore the universe of human proteins at neXtProt for S100A5: NX_P33763

Explore proteomics data for S100A5 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P33763

  • S100A5 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    S100A5 Protein Expression
    REFSEQ proteins: NP_002953.2  
    ENSEMBL proteins: 
     ENSP00000357707   ENSP00000357706   ENSP00000352148  

    Human Recombinant Protein Products for S100A5: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for S100A5
    OriGene Protein Over-expression Lysate for S100A5
    OriGene MassSpec for S100A5 
    OriGene Custom Protein Services for S100A5
    GenScript Custom Purified and Recombinant Proteins Services for S100A5
    Novus Biologicals S100A5 Proteins
    Novus Biologicals S100A5 Lysate
    Sino Biological Recombinant Protein for S100A5
    Browse Sino Biological Cell Lysates 
    ProSpec Recombinant Protein for S100A5
    Cloud-Clone Corp. Proteins for S100A5 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA12118070
    GO:0043025neuronal cell body IEA--

    S100A5 for ontologies           About GeneDecksing



    S100A5 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for S100A5
    GenScript Custom Superior Antibodies Services for S100A5
    Novus Biologicals S100A5 Antibodies
    Abcam antibodies for S100A5
    Cloud-Clone Corp. Antibodies for S100A5 
    Search ThermoFisher Antibodies for S100A5
    LSBio Antibodies in human, mouse, rat for S100A5 

    Assay Products for S100A5: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for S100A5
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for S100A5
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for S100A5 
    Cloud-Clone Corp. CLIAs for S100A5


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    EFHAND: EF-hand domain containing
    S100: S100 calcium binding proteins

    5 InterPro protein domains:
     IPR018247 EF_Hand_1_Ca_BS
     IPR011992 EF-hand-like_dom
     IPR002048 EF_hand_dom
     IPR013787 S100_Ca-bd_sub
     IPR001751 S100/CaBP-9k_CS

    Graphical View of Domain Structure for InterPro Entry P33763

    ProtoNet protein and cluster: P33763

    1 Blocks protein domain: IPB001751 Calcium-binding protein

    UniProtKB/Swiss-Prot: S10A5_HUMAN, P33763
    Similarity: Belongs to the S-100 family
    Similarity: Contains 2 EF-hand domains


    S100A5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: S10A5_HUMAN, P33763
    Function: Binds calcium, zinc and copper. One subunit can simultaneously bind 2 calcium ions or 2 copper ions plus
    1 zinc ion. Calcium and copper ions compete for the same binding sites

         Genatlas biochemistry entry for S100A5:
    S100 calcium binding protein A5,epidermal differentiation complex

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005507copper ion binding IDA19536568
    GO:0005509calcium ion binding IDA19536568
    GO:0008270zinc ion binding IDA19536568
    GO:0042803protein homodimerization activity IPI19536568
         
    S100A5 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for S100A5:
     Increased cell death in breast 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for S100A5 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for S100A5

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for S100A5 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for S100A5 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat S100A5
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate S100A5
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for S100A5
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat S100A5

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for S100A5
    Sirion Biotech Customized adenovirus for overexpression of S100A5

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for S100A5 (see all 6)
    OriGene ORF clones in mouse, rat for S100A5
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: S100A5 (NM_002962)
    Sino Biological Human cDNA Clone for S100A5
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for S100A5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat S100A5
    Sirion Biotech Customized lentivirus for stable overexpression of S100A5 
                         Customized lentivirus expression plasmids for stable overexpression of S100A5 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for S100A5
    Search LifeMap BioReagents cell lines for S100A5
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for S100A5


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for S100A5

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for S100A5 (P337632, 3 ENSP000003521484) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AREGP155142, 3MINT-7256693 I2D: score=1 
    AREGBP155142, 3, ENSP000003702274MINT-7256693 I2D: score=1 STRING: ENSP00000370227
    S100A4ENSP000003462944STRING: ENSP00000346294
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for S100A5 (S10A5)

    Search CenterWatch for drugs/clinical trials and news about S100A5 / S10A5

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for S100A5 gene: 
    NM_002962.1  

    Unigene Cluster for S100A5:

    S100 calcium binding protein A5
    Hs.2960  [show with all ESTs]
    Unigene Representative Sequence: BG200838
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000368718 ENST00000368717 ENST00000359215(uc001fbx.3)

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat S100A5
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate S100A5
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for S100A5
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat S100A5
    Clone
    Products:
         
    OriGene clones in human, mouse for S100A5 (see all 6)
    OriGene ORF clones in mouse, rat for S100A5
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: S100A5 (NM_002962)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for S100A5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat S100A5
    Sirion Biotech Customized lentivirus for stable overexpression of S100A5 
                         Customized lentivirus expression plasmids for stable overexpression of S100A5 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for S100A5
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat S100A5
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat S100A5
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat S100A5

    Additional mRNA sequence: 

    BC093955.1 BC093957.2 Z18954.1 

    2 DOTS entries:

    DT.306595  DT.92070646 

    10 AceView cDNA sequences:

    NM_002962 Z18954 AW090645 AA810909 BG208555 BG212210 BG207000 BG201757 
    BG209078 BG200838 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    S100A5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    S100A5 Expression
    About this image


    See S100A5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for S100A5

    SOURCE GeneReport for Unigene cluster: Hs.2960
        SABiosciences Custom PCR Arrays for S100A5
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for S100A5
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat S100A5
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat S100A5
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat S100A5
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for S100A5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for S100A5 gene from 3/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia S100a51 , 5 S100 calcium binding protein A51, 5 90.94(n)1
    94.57(a)1
      3 (39.27 cM)5
    201991  NM_011312.21  NP_035442.11 
     906085235 
    chicken
    (Gallus gallus)
    Aves --
    --
    44(a)
    1 → many
    25(727119-727862)
    zebrafish
    (Danio rerio)
    Actinopterygii icn6
    icn26
    ictacalcin 2
    40(a)
    39(a)
    many ↔ many
    many ↔ many
    16(25670482-25671845)
    16(25726344-25730386)


    ENSEMBL Gene Tree for S100A5 (if available)
    TreeFam Gene Tree for S100A5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for S100A5 gene
    S100A112  S100A62  S100A12  S100A122  S100B2  S100A42  S100A32  S100A102  
    S100Z2  S100P2  S100A22  S100A92  
    16 SIMAP similar genes for S100A5 using alignment to 2 protein entries:     S10A5_HUMAN (see all proteins):
    S100B    S100A2    S100A6    S100A4    S100A1    S100Z
    S100A12    S100G    S100A13    HRNR    S100A11    S100A3
    S100A9    S100A10    S100A8    S100P

    S100A5 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/151 SNPs in S100A5 are shown (see all 151)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0013054
    ----see VAR_0013052 D G mis40--------
    rs1414845671,2
    --153510752(+) CCTGAA/TGTCCC 1 -- int10--------
    rs1444419941,2
    --153510776(+) TAGGAC/TGATGG 1 -- int10--------
    rs1479924921,2
    --153510828(+) AGCAGA/TTCCTG 1 -- int10--------
    rs1838682031,2
    --153510853(+) TTGCCA/GTCAGC 1 -- int10--------
    rs1416754621,2
    --153510897(+) AAGGCA/GGAAAC 1 -- int10--------
    rs1886459691,2
    --153510908(+) TGCTTC/GTCTGT 1 -- int10--------
    rs1505413131,2
    C--153510969(+) CTGGGA/CGTCTC 1 -- int10--------
    rs1404678551,2
    --153510970(+) TGGGCA/GTCTCT 1 -- int10--------
    rs1446137191,2
    C--153511030(+) ATTAA-/CCTCCA 1 -- int10--------

    HapMap Linkage Disequilibrium report for S100A5 (153509623 - 153514241 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for S100A5:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv831603CNV Gain17160897

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing S100A5
    DNA2.0 Custom Variant and Variant Library Synthesis for S100A5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 176991    OMIM disorders: --

    11 diseases for S100A5:    About MalaCards
    anaplastic astrocytoma    craniopharyngioma    pilocytic astrocytoma    astrocytoma
    meningioma    cholesteatoma    atopic dermatitis    glioblastoma
    dermatitis    alzheimer's disease    endotheliitis


    S100A5 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    4 Novoseek inferred disease relationships for S100A5 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    anaplastic astrocytoma 58.4 1 9989446 (1)
    meningioma 51.4 9 15043715 (5), 15492810 (1), 15542977 (1)
    glioblastoma 40.1 1 9989446 (1)
    tumors 0 4 9989446 (2), 15542977 (1)

    Genetic Association Database (GAD): S100A5
    Human Genome Epidemiology (HuGE) Navigator: S100A5 (1 document)

    Export disorders for S100A5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for S100A5 gene, integrated from 9 sources (see all 23):
    (articles sorted by number of sources associating them with S100A5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Six S100 genes are clustered on human chromosome 1q21: identification of two genes coding for the two previously unreported calcium-binding proteins S100D and S100E. (PubMed id 8341667)1, 2, 3 Engelkamp D.... Heizmann C.W. (1993)
    2. Solution structure and dynamics of S100A5 in the apo and Ca2+-bound states. (PubMed id 19536568)1, 2, 9 Bertini I....Yuan J. (2009)
    3. Hippocampal atrophy as a quantitative trait in a geno me-wide association study identifying novel susceptibility genes for Alzheimer' s disease. (PubMed id 19668339)1, 4 Potkin S.G....Macciardi F. (2009)
    4. Variation in genes of the epidermal differentiation c omplex in German atopic dermatitis patients. (PubMed id 19601998)1, 4 Stemmler S....Hoffjan S. (2009)
    5. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    6. Brain S100A5 is a novel calcium-, zinc-, and copper ion-binding protein of the EF-hand superfamily. (PubMed id 10882717)1, 2 Schaefer B.W.... Cox J.A. (2000)
    7. Differential expression of S100 proteins in the developing human hippocampus and temporal cortex. (PubMed id 12645008)1, 9 Chan W.Y....Yew D.T. (2003)
    8. Restricted expression of calcium-binding protein S100A5 in human kidney. (PubMed id 11855835)1, 9 Teratani T....Nozawa R. (2002)
    9. Development and progression of malignancy in human colon tissues are correlated with expression of specific Ca(2+)-binding S100 proteins. (PubMed id 11510959)1, 9 Bronckart Y....Heizman C.W. (2001)
    10. Clustered organization of S100 genes in human and mouse. (PubMed id 9920416)1, 9 Ridinger K....Schafer B.W. (1998)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6276 HGNC: 10495 AceView: S100A5 Ensembl:ENSG00000196420 euGenes: HUgn6276
    ECgene: S100A5 H-InvDB: S100A5

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for S100A5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for S100A5 gene:
    Search GeneIP for patents involving S100A5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for S100A5  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for S100A5  
     OriGene MassSpec something-or-other for S100A5   OriGene clones in human, mouse for S100A5  
     OriGene qSTAR qPCR primer pairs in human, mouse for S100A5   OriGene Purified Protein for S100A5  
     OriGene ORF clones in mouse, rat for S100A5   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for S100A5   OriGene Custom Protein Services for S100A5  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat S100A5
     QIAGEN SeqTarget long-range PCR primers for resequencing S100A5
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat S100A5
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat S100A5
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat S100A5
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat S100A5
     GenScript Custom Purified and Recombinant Proteins Services for S100A5 GenScript cDNA clones with any tag delivered in your preferred vector for S100A5
     GenScript Custom Assay Services for S100A5 GenScript Custom Superior Antibodies Services for S100A5
     GenScript Custom overexpressing Cell Line Services for S100A5 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in S100A5 promoter
     Search Chromatin IP Primers for S100A5
     RT2 qPCR Primer Assay in human, mouse, rat S100A5
     Search GNC Networks for S100A5
     SABiosciences Custom PCR Arrays for S100A5
     Search Tocris compounds for S100A5 (S10A5)
     Proteins and Antibodies for S100A5
     Browse Sino Biological Cell Lysates
     cDNA Clones for S100A5
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     S100A5 antibodies
     S100A5 proteins
     S100A5 lysates
     Antibodies for S100A5
     See all of Abcam's Antibodies, Kits and Proteins for S100A5
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Recombinant Protein for S100A5




     Proteins for S100A5
     Antibodies for S100A5
     ELISAs for S100A5
     CLIAs for S100A5
     Search LifeMap BioReagents cell lines for S100A5
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for S100A5
     Browse SwitchGear 3'UTR luciferase reporter plasmids for S100A5
     SwitchGear Promoter luciferase reporter plasmids for S100A5
     Search ThermoFisher Antibodies for S100A5
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat S100A5
     inGenious Targeting Laboratory - Custom generated mouse model solutions for S100A5
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for S100A5
    Customized:
     lentivirus for stable overexpression of S100A5
     lentivirus expression plasmids for stable overexpression of S100A5
     adenovirus for overexpression of S100A5
     LSBio Antibodies in human, mouse, rat for S100A5
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      S100A5 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4