Aliases for S100A5 Gene
External Ids for S100A5 Gene
Previous HGNC Symbols for S100A5 Gene
Previous GeneCards Identifiers for S100A5 Gene
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has a Ca2+ affinity 20- to 100-fold higher than the other S100 proteins studied under identical conditions. This protein also binds Zn2+ and Cu2+, and Cu2+ strongly which impairs the binding of Ca2+. This protein is expressed in very restricted regions of the adult brain. [provided by RefSeq, Jul 2008]
GeneCards Summary for S100A5 Gene
S100A5 (S100 Calcium Binding Protein A5) is a Protein Coding gene. GO annotations related to this gene include calcium ion binding and copper ion binding. An important paralog of this gene is S100A6.
UniProtKB/Swiss-Prot for S100A5 Gene
Binds calcium, zinc and copper. One subunit can simultaneously bind 2 calcium ions or 2 copper ions plus 1 zinc ion. Calcium and copper ions compete for the same binding sites.