Aliases for S100A3 Gene
External Ids for S100A3 Gene
Previous HGNC Symbols for S100A3 Gene
Previous GeneCards Identifiers for S100A3 Gene
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has the highest content of cysteines of all S100 proteins, has a high affinity for Zinc, and is highly expressed in human hair cuticle. The precise function of this protein is unknown. [provided by RefSeq, Jul 2008]
GeneCards Summary for S100A3 Gene
S100A3 (S100 Calcium Binding Protein A3) is a Protein Coding gene. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is S100A6.
UniProtKB/Swiss-Prot for S100A3 Gene
Binds both calcium and zinc. May be involved in calcium-dependent cuticle cell differentiation, hair shaft and hair cuticular barrier formation.