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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

S100A2 Gene

protein-coding   GIFtS: 65
GCID: GC01M153533

S100 calcium binding protein A2

(Previous name: S100 calcium-binding protein A2 )
(Previous symbol: S100L)
 Explore 48 diseases affiliated with
S100A2 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for S100A2    

Aliases
for S100A2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
S100 Calcium Binding Protein A21 2
S100L1 2 3 5
CAN191 2 3
S100 Calcium-Binding Protein A21 2 3
Protein S100-A22
Protein S-100L3

External Ids:    HGNC: 104921   Entrez Gene: 62732   Ensembl: ENSG000001967547   OMIM: 1769935   UniProtKB: P290343   

Export aliases for S100A2 gene to outside databases

Previous GC identifers: GC01M151349 GC01M149316 GC01M150360 GC01M150802 GC01M150346 GC01M151800 GC01M124896


Summaries
for S100A2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for S100A2:
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding
motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the
regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at
least 13 members which are located as a cluster on chromosome 1q21. This protein may have a tumor suppressor function.
Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer. (provided by
RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: S10A2_HUMAN, P29034
Function: May act as a modulator against excess calcium accumulation in normal human mammary epithelial cells. May also
play a role in suppressing tumor cell growth

Gene Wiki entry for S100A2


Genomic Views
for S100A2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the S100A2 gene promoter:
         Egr-2   p53   FOXJ2 (long isoform)   FOXJ2   Nkx2-5   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: S100A2 promoter sequence
   Search SABiosciences Chromatin IP Primers for S100A2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat S100A2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21   Ensembl cytogenetic band:  1q21.3   HGNC cytogenetic band: 1q21

S100A2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
S100A2 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M153533:  view genomic region     (about GC identifiers)

Start:
 153,533,584 bp from pter      End:
 153,540,366 bp from pter
Size:
 6,783 bases      Orientation:
 minus strand

Proteins
for S100A2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: S10A2_HUMAN, P29034 (See protein sequence)
Recommended Name: Protein S100-A2  
Size: 98 amino acids; 11117 Da
Subunit: Homodimer. Interacts with FKBP4
Developmental stage: Preferentially expressed in normal human mammary epithelial cells as opposed to tumor-derived
ones. The level of S100L was shown to correlate inversely with tumor progression
Miscellaneous: This protein binds two calcium ions (By similarity)
Caution: It is uncertain whether Met-1 or Met-2 is the initiator
Sequence caution: Sequence=CAA69033.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
2 PDB 3D structures from and Proteopedia for S100A2:
2RGI (3D)        4DUQ (3D)    
Secondary accessions: O00266 Q3KRB9 Q5RHS8 Q9BU83

Explore the universe of human proteins at neXtProt for S100A2: NX_P29034

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P29034

    • S100A2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_005969.1  
    ENSEMBL proteins: 
     ENSP00000357697   ENSP00000357699   ENSP00000357698   ENSP00000357696  

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    ProSpec Recombinant Protein for S100A2
    Uscn Proteins for S100A2

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--


    S100A2 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for S100A2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    S100A2 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR018247 EF_Hand_1_Ca_BS
     IPR011992 EF-hand-like_dom
     IPR002048 EF_hand_Ca-bd
     IPR013787 S100_Ca-bd_sub
     IPR001751 S100/CaBP-9k_CS

    Graphical View of Domain Structure for InterPro Entry P29034

    ProtoNet protein and cluster: P29034

    1 Blocks protein family: IPB001751 Calcium-binding protein

    UniProtKB/Swiss-Prot: S10A2_HUMAN, P29034
    Similarity: Belongs to the S-100 family
    Similarity: Contains 2 EF-hand domains


    Function
    for S100A2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: S10A2_HUMAN, P29034
    Function: May act as a modulator against excess calcium accumulation in normal human mammary epithelial cells. May also
    play a role in suppressing tumor cell growth
    Induction: By growth factors in early G1 phase and probably by cell-cycle regulation in S phase. DNA methylation
    probably plays a direct negative role in suppressing S100L gene expression in tumor cells

         Genatlas biochemistry entry for S100A2:
    S100 calcium binding protein A2,epidermal diffentiation complex

    miRNA
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    Gene Editing
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    Clone
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    In Situ Assay
    Products:       
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding NAS9481475


    S100A2 for ontologies           About GeneDecksing



    Pathways & Interactions
    for S100A2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Direct p53 effectors
    		Direct p53 effectors1.00
    2Selected targets of p53
    		Selected targets of p531.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for S100A2
        Selected targets of p53


    1 BioSystems Pathway for S100A2 
        Direct p53 effectors



    S100A2 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for S100A2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/36 Interacting proteins for S100A2 (P290342, 3 ENSP000003576974) via UniProtKB, MINT, STRING, and/or I2D (see all 36)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    KPNA2P522922, 3, ENSP000003324554MINT-8044917 MINT-8045244 MINT-8045302 MINT-8044951 MINT-8045267 I2D: score=1 STRING: ENSP00000332455
    FKBP4Q027902, 3, ENSP000000010084MINT-7710374 MINT-7710476 MINT-7710432 I2D: score=1 STRING: ENSP00000001008
    TP53P046372, 3, ENSP000002693054MINT-7905347 MINT-7905185 I2D: score=3 STRING: ENSP00000269305
    MDM2Q009872, 3, ENSP000004172814MINT-7905238 MINT-7905090 I2D: score=2 STRING: ENSP00000417281
    AREGBP155142, 3, ENSP000003702274MINT-7256654 I2D: score=1 STRING: ENSP00000370227
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0043542endothelial cell migration IMP15313892


    S100A2 for ontologies           About GeneDecksing



    Drugs & Compounds
    for S100A2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    S100A2 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for S100A2

    1 HMDB Compound for S100A2    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    1 DrugBank Compound for S100A2    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Olopatadine-- 113806-05-6targetantagonist11944917

    8 Novoseek chemical compound relationships for S100A2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    5-aza-2'deoxycytidine 51 5 17785578 (3), 11691825 (1)
    calcium 32.8 23 9668057 (4), 12445212 (4), 17239974 (3), 16015609 (2) (see all 10)
    zinc 29.9 16 17239974 (6), 10788426 (2), 9668057 (2), 19386136 (1)
    oligonucleotide 13 4 16367903 (2), 14519656 (1)
    etoposide 4.4 5 10094469 (4), 11005251 (1)
    tyrosine 0 3 17874182 (1), 10788426 (1), 9856822 (1)
    cysteine 0 4 10788426 (2), 10951287 (1)
    h2o2 0 7 12445212 (3), 10951287 (1)

    Search CenterWatch for drugs/clinical trials and news about S100A2 / S10A2 

    Transcripts
    for S100A2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for S100A2 gene: 
    NM_005978.3  

    Unigene Cluster for S100A2:

    S100 calcium binding protein A2
    Hs.516484  [show with all ESTs]
    Unigene Representative Sequence: BU589956
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000368708(uc001fcb.3) ENST00000487430 ENST00000497140 ENST00000368710
    ENST00000368709 ENST00000368707

    miRNA
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    hsa-miR-561 hsa-miR-3176 hsa-miR-3922-3p
    SwitchGear 3'UTR luciferase reporter plasmid: S100A2 3' UTR sequence
    Inhib. RNA
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    Clone
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    Primer
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    Additional cDNA sequence: 

    AF086003.1 BC002829.2 BC105787.1 M87068.1 

    9 DOTS entries:

    DT.91778144  DT.100889674  DT.99953485  DT.100889712  DT.100889706  DT.91778121  DT.100045252  DT.121366802 
    DT.95375649 

    24/133 AceView cDNA sequences (see all 133):

    BF149223 BM549544 AA593632 NM_005978 BM839923 AA586847 C00151 AI436747 
    CD365047 BM979834 BM980620 AA594885 BM976343 BM550262 BI335835 H64656 
    CA435200 AA458884 AA459074 BX119419 C00271 AA596012 CA748677 AF086003 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for S100A2    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4
    SP1:                                    
    SP2:                          -         
    SP3:                          -         
    SP4:              -           -         


    ECgene alternative splicing isoforms for S100A2

    Expression
    for S100A2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    S100A2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GATCTCTTGG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    S100A2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Cardiomyocyte-like cells (Spontaneous differen...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See S100A2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for S100A2

    SOURCE GeneReport for Unigene cluster: Hs.516484

    UniProtKB/Swiss-Prot: S10A2_HUMAN, P29034
    Tissue specificity: A subset of epithelial cells including normal human mammary epithelial cells and keratinocytes

        SABiosciences Custom PCR Arrays for S100A2
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    In Situ
    Assay Products:     
         		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for S100A2

    Orthologs
    for S100A2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for S100A2 gene from 1/5 species (see all 5)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    zebrafish
    (Danio rerio)    		 Actinopterygii icn6
    icn26
    (see all 4)    		 ictacalcin 2
    (see all 4)    		 51(a)
    47(a)
    (see all 4)    		 many ↔ many
    many ↔ many
    (see all 4)    		 16(25670482-25671845)
    16(25726344-25730386)


    ENSEMBL Gene Tree for S100A2 (if available)
    TreeFam Gene Tree for S100A2 (if available) 

    Paralogs
    for S100A2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for S100A2 gene
    S100A112  S100A62  S100A12  S100A122  S100A82  S100B2  S100A42  S100A32  
    S100A102  S100Z2  S100P2  S100A52  S100A92  
    18/19 SIMAP similar genes for S100A2 using alignment to 2 protein entries:     S10A2_HUMAN (see all proteins) (see all similar genes):
    S100A9    HRNR    S100A4    S100A16    S100B    FLG2
    S100A11    S100A12    S100A13    S100A5    S100G    S100A6
    S100Z    S100A1    RPTN    S100P    S100A3    S100A8

    S100A2 for paralogs           About GeneDecksing



    Genomic Variants
    for S100A2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/147 NCBI SNPs in S100A2 are shown (see all 147)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 1 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1159684451,2
    		F,--153533183(+) CAGGTT/GCAAGC 1 -- ds50011Minor allele frequency- G:0.10NA 120
    rs1432363801,2
    		--153533231(+) CAGGCA/GTGTAC 1 -- ds50010--------
    rs1390818691,2
    		--153533385(+) TGCTCA/GGTCTA 1 -- ds50010--------
    rs1815539001,2
    		--153533438(+) TAATTA/CATATC 1 -- ds50010--------
    rs1862778341,2
    		--153533501(+) CTGTCC/TTTTAT 1 -- ds50010--------
    rs752827961,2
    		--153533840(+) AAGTTC/TATTGA 1 -- ut310--------
    rs22338691,2
    		C,--153533893(-) TCCTGC/GCATGG 1 -- ut310--------
    rs84011,2
    		C,F,H,--153533898(-) TGACTT/CCCTGC 1 -- ut3125Minor allele frequency- C:0.18NA NS EA WA CSA EU 3583
    rs1440546051,2
    		C,F--153533923(+) GGGTCG/AGTCTG 2 /R /* stg11Minor allele frequency- A:0.00NA 4552
    rs413008571,2
    		C,,--153534013(+) GTCACC/TGTTCT 2 S G mis10--------

    HapMap Linkage Disequilibrium report for S100A2 (153533584 - 153540366 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for S100A2: --

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    Disorders / Diseases
    for S100A2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    S100A2 for disorders           About GeneDecksing

    OMIM gene information: 176993    OMIM disorders: --

    20/48 diseases for S100A2 (see all 48):    About MalaCards
    malignant peripheral nerve sheath tumor    breast cancer    non-small cell lung carcinoma    squamous cell carcinoma
    actinic keratosis    barrett's esophagus    laryngeal squamous cell carcinoma    pilocytic astrocytoma
    pilomatrixoma    oral squamous cell carcinoma    esophageal squamous cell carcinoma    lung squamous cell carcinoma
    atopic dermatitis    keratosis    anaplastic astrocytoma    chondroblastoma
    barrett's adenocarcinoma    carcinoma    craniopharyngioma    oral cancer

    1 disease from the University of Copenhagen DISEASES database for S100A2:
    Carcinoma

    10/23 Novoseek disease relationships for S100A2 gene (see all 23)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    carcinoma squamous cell 57.7 20 11304580 (3), 16273244 (3), 16908593 (2), 11956617 (2) (see all 12)
    nsclc 44.8 28 19118029 (6), 15800916 (3), 19238334 (3), 18656279 (2) (see all 8)
    adenocarcinoma 44.6 11 17032501 (2), 17940995 (1), 16015609 (1), 18656279 (1) (see all 7)
    tumors 41.5 66 17032501 (4), 11956617 (4), 9481475 (3), 11304580 (3) (see all 28)
    oral cancer 33.3 3 15792606 (3)
    pancreatic cancer 31.8 7 17940995 (4), 17200013 (3)
    melanoma 31.6 15 9291441 (4), 12652189 (2), 9162739 (2), 9274623 (2) (see all 6)
    cancer 27.5 9 11813862 (1), 17289885 (1), 12506178 (1), 16908593 (1) (see all 7)
    cancer lung 27.3 5 15800916 (1), 19118029 (1), 18656279 (1), 11691825 (1)
    adenocarcinoma lung 24.6 6 16367903 (4), 16232198 (1)

    Genetic Association Database (GAD): S100A2
    Human Genome Epidemiology (HuGE) Navigator: S100A2 (4 documents)

    Export disorders for S100A2 gene to outside databases

    Publications
    for S100A2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for S100A2 gene, integrated from 9 sources (see all 122):
    (articles sorted by number of sources associating them with S100A2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Repression of the candidate tumor suppressor gene S100A2 in breast cancer is mediated by site-specific hypermethylation. (PubMed id 9481475)1, 2, 9 Wicki R.... Schaefer B.W. (1997)
    2. S100A2 coding sequence polymorphism: characterization and lack of association with psoriasis. (PubMed id 11260185)1, 4, 9 Stoll S.W....Elder J.T. (2001)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Six S100 genes are clustered on human chromosome 1q21: identification of two genes coding for the two previously unreported calcium-binding proteins S100D and S100E. (PubMed id 8341667)1, 3 Engelkamp D.... Heizmann C.W. (1993)
    6. Down-regulation of a member of the S100 gene family in mammary carcinoma cells and reexpression by azadeoxycytidine treatment. (PubMed id 1372446)1, 2 Lee S.W.... Sager R. (1992)
    7. Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes. (PubMed id 1286667)1, 2 Rasmussen H.H....Vandekerckhove J. (1992)
    8. Differential responses of S100A2 to oxidative stress and increased intracellular calcium in normal, immortalized, and malignant human keratinocytes. (PubMed id 12445212)1, 9 Zhang T....Elder J.T. (2002)
    9. Biochemical characterization of S100A2 in human keratinocytes: subcellular localization, dimerization, and oxidative cross-linking. (PubMed id 10951287)1, 9 Deshpande R....Elder J.T. (2000)
    10. Expression and clinical significance of S100A2 and p6 3 in esophageal carcinoma. (PubMed id 19725154)1, 9 Cao L.Y....Zhang H.F. (2009)

    External Searches for S100A2 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  
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    Genome Databases showing S100A2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6273 HGNC: 10492 AceView: S100A2 Ensembl:ENSG00000196754 euGenes: HUgn6273
    ECgene: S100A2 H-InvDB: S100A2

    Other Databases showing S100A2 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing S100A2 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for S100A2 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for S100A2 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for S100A2 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for S100A2 gene:
    Search GeneIP for patents involving S100A2

    GeneCards and IP:
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